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Bridging Molecular Docking to Molecular Dynamics to Enlighten Recognition Processes of Tailored D-A/D-A-D Types' AIEgens with HSA/BSA
Published 2023-09-01“…Subsequently, molecular dynamics simu-lations were also performed for the best-docked ligands: macromolecule complexes; namely D1A1D1:BSA and D1A1:HSA, to enlighten various structural parameters. …”
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Multicomponent Nanocomposites for Complex Anticancer Therapy: Effect of Aggregation Processes on Their Efficacy
Published 2020-01-01“…The decrease in the activity of the four-component systems is explained by the aggregation process caused by the introduction of an additional component, which leads to a decrease in the hydrophilic-hydrophobic balance of the polymer macromolecule.…”
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Research progress on protective effect of polysaccharide from traditional Chinese medicine on myocardial ischemia-reperfusion injury
Published 2025-01-01“…Myocardial ischemia-reperfusion injury (MIRI) is a prevalent pathophysiological process associated with ischemic heart disease and significantly exacerbates myocardial damage, particularly in the elderly population.This condition not only poses serious risks to individual health but also brings creates substantial societal and economic burdens.Polysaccharides, natural macromolecule found in animals, plants and microorganisms, serve as active substance that confer various health benefits.Among these, polysaccharides extracted from traditional Chinese medicine(TCM) through modern scientific techniques have gained prominence in the medical field due to their safety and high efficiency, playing a vital role in the management of various cardiovascular diseases.This paper, provides a comprehensive review of the role and mechanisms of TCM-derived polysaccharide in MIRI, aiming to furnish valuable insights for the future treatment of cardiovascular diseases in the elderly.…”
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Recent advances in the anti-tumor activities of saponins through cholesterol regulation
Published 2025-01-01“…It will also outline how saponins exert their anti-cancer activities through cholesterol regulation, enhancing cytotoxicity, inhibiting tumor cell metastasis, reversing drug resistance, inducing immunotoxin macromolecule escape, and ferroptosis. This comprehensive analysis offers insights into the potential for the use of saponins anti-tumor therapies and their combinations with other drugs, advancing the understanding of their effects on cancer cells.…”
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Nutrients Release from a Novel Gel-Based Slow/Controlled Release Fertilizer
Published 2016-01-01“…A novel gel-based slow/controlled release fertilizer (G-CRF) was developed, which was produced by combining various natural, seminatural, and/or synthetic organic macromolecule materials and natural inorganic mineral with conventional NPK fertilizers. …”
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Recent Advances, Research Trends, and Clinical Relevance of Hyaluronic Acid Applied to Wound Healing and Regeneration
Published 2025-01-01“…Hyaluronan (HA) is a ubiquitous macromolecule in the human body with remarkable structure and function. …”
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Influence of the Adsorption of Polyethylene Glycol at the A1O Surface on the Electrochemical Properties of the Al O/Solution Interface
Published 1999-03-01“…The pH of the solution also affects the thickness of the adsorbed layers on the A1 2 O 3 surface by influencing the interaction between the surface groups of the oxide and the conformational structures of the adsorbed macromolecule at the alumina/polymer solution interface.…”
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Enhanced Antibacterial Activity of Hydrophobic Modified Lysozyme Against Gram-Negative Bacteria Without Accumulated Resistance
Published 2025-01-01“…Macromolecule bactericides present challenges such as low biocompatibility and not being biodegradable, so broad-spectrum bactericides without accumulated bacteria resistance are now in urgent demand all over the world. …”
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Micellization Studies on Binary Mixture of Methionine with Polyoxyethylene (10) Cetyl Ether (Brij-56) and Polyoxyethylene (20) Cetyl Ether (Brij-58)
Published 2010-01-01“…The measurement of cloud point (CP) under the influence of additives provides an excellent tool for investigation of surfactant macromolecule interaction. The CP of pure surfactant polyoxyethylene (10) cetyl ether (Brij-56) and polyoxyethylene (20) cetyl ether (Brij-58) declined with increased [Bj-56] and [Bj-58]. …”
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Separation and purification of bromelain from pineapple residue using ultrafiltration membranes: a review
Published 2024-12-01“…Ultrafiltration (UF), widely applied in macromolecule retention processes, faces significant challenges such as fouling, which limits its effectiveness. …”
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Optofluidic paper-based analytical device for discriminative detection of organic substances via digital color coding
Published 2025-01-01“…Herein, we propose an optofluidic paper-based analytical device (PAD) that consists of a macromolecule-driven flow (MDF) gate and photonic crystal (PhC) coding units, enabling portable and scalable detection and discrimination of various organic chemical, mimicking the olfactory system. …”
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A Systemic Network Triggered by Human Cytomegalovirus Entry
Published 2011-01-01“…The up-regulated network contains various functional modules, such as cell surface receptors, skeletal development, endocytosis, ion transport, and chromatin remodeling. Interestingly, macromolecule metabolism and chromatin remodeling module predominates this over-expressed system, suggesting that the fundamental nuclear process modulation is one of the most important events in HCMV entry. …”
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Recent Advances in Paper Conservation Using Nanocellulose and Its Composites
Published 2025-01-01“…As a new type of biological macromolecule, nanocellulose has been extensively utilized in paper conservation, attributed to its excellent paper compatibility, high optical transparency, outstanding mechanical strength, and large specific surface area with abundant hydroxyl groups. …”
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Adsorption of Cu (II) and Cd (II) from Wastewater by Sodium Alginate Modified Materials
Published 2020-01-01“…Natural macromolecule adsorbing materials are alternatives for remediation of heavy metals’ polluted waters. …”
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The Impact of Pore Structure on Kerogen Geomechanics
Published 2021-01-01“…Nanoporous kerogen structures across a range of densities were formed from single macromolecule units. Eight units were initially placed in a low-density cell. …”
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Optimized PCF architectures for THz detection of aquatic pathogens: Enhancing water quality monitoring.
Published 2025-01-01“…It targets bacterial macromolecule absorption peaks to increase sensitivity. …”
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Preparation and Assessment of Surface and Functional Properties of Protein Blends from Moringa oleifera and Monodora myristica Seeds
Published 2025-02-01“… Protein, an amphoteric macromolecule has proven to play important role in enhancing nutritive standard and product quality. …”
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Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival
Published 2025-01-01“…Abstract One hallmark of cancer is the upregulation and dependency on glucose metabolism to fuel macromolecule biosynthesis and rapid proliferation. Despite significant pre-clinical effort to exploit this pathway, additional mechanistic insights are necessary to prioritize the diversity of metabolic adaptations upon acute loss of glucose metabolism. …”
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