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Roles of Inflammasomes in Inflammatory Kidney Diseases
Published 2019-01-01“…Inflammasomes are macromolecules consisting of multiple proteins, and their formation initiates the cleavage of procaspase-1, resulting in the activation of gasdermin D as well as the maturation and release of interleukin-1β and IL-18, leading to pyroptosis. …”
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62
Research of Inonotus obliquus Oligosaccharide in Prevention of Hyperlipidemia
Published 2021-01-01“…Among them, 1,4-glycosidic bonds accounted for 9.2%, and 1,6-glycosidic bonds accounted for 85.1%. Oligosaccharide macromolecules formed a layered structure. Mouse experiments showed that IOP-2A had the function of preventing hyperlipidemia. …”
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63
Intestinal Permeability Assays: a Review
Published 2021-04-01“…The intestinal barrier integrity and permeability assays differ by the application setting (in vivo or ex vivo), subject (human or animal), marker molecules used to assess permeability (ions, various size carbohydrates, macromolecules, antigens, bacterial products and bacteria), biomaterial for the marker concentration assays (peripheral blood, portal venous blood, urine, stool). …”
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64
Physicochemical Characteristics of Chitosan–Alginate Scaffold Containing Atorvastatin
Published 2023-01-01“…Owing to its high porosity and swelling, the CS/ALG hydrogel crosslinked with PPT is an ideal scaffold for loading drugs, macromolecules, and cells.…”
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65
Study on the Interaction between Cadmium Sulphide Nanoparticles and Proteins by Resonance Rayleigh Scattering Spectra
Published 2013-01-01“…Below the isoelectric point, proteins such as bovine serum albumin (BSA), human serum albumin (HSA), lysozyme (Lys), hemoglobin (HGB), and ovalbumin (OVA) can bind with CdSn to form macromolecules by virtue of electrostatic attraction and hydrophobic force. …”
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66
Parallelizing the cryo‐EM structure determination in THUNDER using GPU cluster
Published 2025-01-01“…However, obtaining high‐resolution 3D reconstructions from innumerable noisy images of macromolecules is an extremely complicated task, involving massive image analysis and calculation on a computing cluster. …”
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67
Fenofibrate Protects Cardiomyocytes from Hypoxia/Reperfusion- and High Glucose-Induced Detrimental Effects
Published 2021-01-01“…Lesions caused by high glucose (HG), hypoxia/reperfusion (H/R), and the coexistence of both conditions in cardiomyocytes are linked to an overproduction of reactive oxygen species (ROS), causing irreversible damage to macromolecules in the cardiomyocyte as well as its ultrastructure. …”
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68
Dynamic Change of Polymer in Rice Analogues and Its Effect on Texture Quality
Published 2020-01-01“…Macromolecules will leach from the inside of rice analogues (RA) to the external environment and form escaping substances (ES) when boiling in water for a long time. …”
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69
Sulfated and Phosphorylated Agarose as Biomaterials for a Biomimetic Paradigm for FGF-2 Release
Published 2024-12-01“…To access injectable biomaterials that can mimic such natural electrostatic interactions between soluble signals and macromolecules and mechanically tunable environments, the backbone of agarose, a thermogelling marine–algae-derived polysaccharide, was modified with sulfate, phosphate, and carboxylic moieties and the interaction and release of FGF-2 from these functionalized hydrogels was assessed by ELISA in vitro and CAM assay in ovo. …”
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70
Study of the Adsorption Mechanism and the Structure of Adsorbed Layers of Polyelectrolytes at the Metal Oxide/Solution Interface
Published 2001-06-01“…The calculated concentrations of the various surface groups on ZrO 2 and Fe 2 O 3 enabled an investigation of the possible mechanism for the bonding of the studied polyelectrolytes with the surfaces of both oxides. PAA and PAM macromolecules bond with the solid surface mainly via the –OH groups of the oxides, which may interact with the carboxy groups of polyelectrolytes through hydrogen bridging. …”
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71
Scaffold-enabled high-resolution cryo-EM structure determination of RNA
Published 2025-01-01“…These difficulties are compounded for small RNAs as cryo-EM is inherently more difficult for lower molecular weight macromolecules. Here we present a strategy for fusing small RNAs to a group II intron that yields high resolution structures of the appended RNA. …”
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72
Natural Protein Films from Textile Waste for Wound Healing and Wound Dressing Applications
Published 2025-01-01“…In recent years, several studies have focused on the development of sustainable, biocompatible, and biodegradable films with potential applications in wound healing and wound dressing systems. Natural macromolecules, particularly proteins, have emerged as attractive alternatives to synthetic polymers due to their biocompatibility, biodegradability, low immunogenicity, and adaptability. …”
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73
Statistical Evaluations of the Reproducibility and Reliability of 3-Tesla High Resolution Magnetization Transfer Brain Images: A Pilot Study on Healthy Subjects
Published 2010-01-01“…At 3 Tesla (T), MT affords higher resolution and increased tissue contrast associated with macromolecules. The reliability and reproducibility of a new high-resolution MT strategy were assessed in brain images acquired from 9 healthy subjects. …”
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74
Short-term airborne ultrasound induced cell death in tobacco cells and changed their wall components
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75
Scalable fabrication of an array-type fixed-target device for automated room temperature X-ray protein crystallography
Published 2025-01-01“…Abstract X-ray crystallography is one of the leading tools to analyze the 3-D structure, and therefore, function of proteins and other biological macromolecules. Traditional methods of mounting individual crystals for X-ray diffraction analysis can be tedious and result in damage to fragile protein crystals. …”
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76
New fruit waste-derived activated carbons of high adsorption performance towards metal, metalloid, and polymer species in multicomponent systems
Published 2025-01-01“…It was noted that microwave heating favoured surface development and thus enhanced adsorbent ability to bind ions or macromolecules. Direct biomass activation led to higher microporosity compared to indirect (two-stage) one, whilst CO2-consuming activation increased aromaticity and hydrophobicity of the solids. …”
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77
MPicker: visualizing and picking membrane proteins for cryo-electron tomography
Published 2025-01-01“…Abstract Advancements in cryo-electron tomography (cryoET) allow the structure of macromolecules to be determined in situ, which is crucial for studying membrane protein structures and their interactions in the cellular environment. …”
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78
Supramolecular Biopolymers for Tissue Engineering
Published 2021-01-01“…Supramolecular biopolymers (SBPs) are those polymeric units derived from macromolecules that can assemble with each other by noncovalent interactions. …”
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79
Enter the Matrix: Fibroblast-immune cell interactions shape extracellular matrix deposition in health and disease. [version 2; peer review: 1 approved, 2 approved with reservations...
Published 2024-12-01“…Fibroblasts regulate the composition of the extracellular matrix (ECM), a 3-dimensional network of macromolecules that comprise the acellular milieu of tissues. …”
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Characteristics and microscopic mechanisms of smoke emissions of OMMT/SBS-modified asphalt
Published 2025-01-01“…The incorporation of OMMT increases the macromolecule content in the modified asphalt, showing that OMMT inhibited the decomposition of asphalt macromolecules into smaller molecules, thus reducing the release of VOCs. …”
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