Leveraging Next-Generation Sequencing Application from Identity to Purity Profiling of Nucleic Acid-Based Products by Rucha Wadapurkar, Swarda Deo, Renuka Khanzode, Ajay Singh

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COVID-19 Vaccine Booster Dose Fails to Enhance Antibody Response to Omicron Variant in Reinfected Healthcare Workers by Leire Fernández-Ciriza, Álvaro González, José Luis del Pozo, Alejandro Fernandez-Montero, Francisco Carmona-Torre, Paula Martínez de Aguirre, María del Mar Sarasa, Silvia Carlos, Gabriel Reina

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Efficiency enhancement in main path extraction in mRNA vaccine field: A novel approach leveraging intermediate patents, with shielding origin and terminus patent edges by Ting Zhang, Zhongquan Jian, Juan Chen, Dongzi Xu, Xiaoyi Yang, Yan Lu, Shu Yan, Lizi Pan, Qingqiang Wu, Zhaolian Ouyang

Subjects: “…mRNA vaccine…”
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Avian influenza mRNA vaccine encoding hemagglutinin provides complete protection against divergent H5N1 viruses in specific-pathogen-free chickens by Zhaoyang Wang, Chongyu Tian, Jiahang Zhu, Shiqian Wang, Xiang Ao, Yanjuan He, Huixin Chen, Xiuying Liao, Deming Kong, Yongfei Zhou, Wanbo Tai, Ming Liao, Huiying Fan

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An mRNA-Based Respiratory Syncytial Virus Vaccine Elicits Strong Neutralizing Antibody Responses and Protects Rodents Without Vaccine-Associated Enhanced Respiratory Disease by Jianglong Li, Haiyan Long, Shaoyi Chen, Zhendong Zhang, Shuang Li, Qi Liu, Jun Liu, Jiaru Cai, Liping Luo, Yucai Peng

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Safety and immunogenicity of an mRNA-1273 vaccine booster in adolescents by Amparo L. Figueroa, Kashif Ali, Gary Berman, Wenqin Xu, Weiping Deng, Bethany Girard, Anne Yeakey, Karen Slobod, Jacqueline Miller, Rituparna Das, Frances Priddy

Subjects: “…mRNA vaccine…”
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Acute zonal occult outer retinopathy (AZOOR) complex associated with torpedo retinopathy following COVID-19 recombinant mRNA vaccination: a case report of a rare clinical presentation by Nai-Wen Chang, Chia-hao Kuo, Hung-Da Chou, Yi-Hsing Chen

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Heterologous vaccination with subunit protein vaccine induces a superior neutralizing capacity against BA.4/5‐included SARS‐CoV‐2 variants than homologous vaccination of mRNA vaccine by Dandan Peng, Tingmei Zhao, Weiqi Hong, Minyang Fu, Cai He, Li Chen, Wenyan Ren, Hong Lei, Jingyun Yang, Aqu Alu, Yanghong Ni, Jian Liu, Jiong Li, Wei Wang, Guobo Shen, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Yoshimasa Tanaka, Guangwen Lu, Xiangrong Song, Xiawei Wei

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Transient Pneumonitis as a Possible Adverse Reaction to the BNT162b2 COVID-19 mRNA Vaccine in a Patient with Rheumatoid Arthritis: A Case Report and Review of the Literature by Yusuke Ohkubo, Shin-ichiro Ohmura, Ryuhei Ishihara, Toshiaki Miyamoto

“…Herein, we describe a case of pneumonitis following COVID-19 mRNA vaccination in a patient with rheumatoid arthritis, which resolved spontaneously.…”
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One Year Duration of Immune Response Following a 3rd Booster Dose of mRNA Vaccine Against COVID‐19 in 292 Patients With Hematological Malignancies in University Hospital Ostrava, Czech Republic by Ondrej Šušol, Barbora Šušolová, Ondřej Klempíř, Milan Navrátil, Jaromír Gumulec, Zdeněk Kořístek, Juraj Ďuraš, Michal Kaščák, Jana Mihályová, Lukáš Stejskal, Tomáš Jelínek, Petra Richterová, Lenka Szeligová, Hana Plonková, Jana Zuchnická, Barbora Dluhošová, Ivo Demel, David Buffa, Katarína Hradská, Tereza Popková, Ludmila Muroňová, Martin Lachnit, Klára Lančová, Roman Hájek

“…ABSTRACT Aims To evaluate antibody response to mRNA vaccine, identify subgroups with poor response and to determine long‐term antibody durability in hematological patients. …”
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Impact of Metabolic States on SARS-CoV-2 Vaccine Responses in Mouse Models of Obesity and Diabetes by Olivia A. Smith, Brent Fujimoto, Teri Ann S. Wong, Albert To, Troy Odo, Aquena Ball, Brien K. Haun, Hiromi Muramatsu, Ying K Tam, Norbert Pardi, Axel T. Lehrer

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Longitudinal immunogenicity cohort study of SARS-CoV-2 mRNA vaccines across individuals with different immunocompromising conditions: heterogeneity in the immune response and crucial role of Omicron-adapted booster dosesResearch in context by Annalisa Ciabattini, Elena Pettini, Fabio Fiorino, Jacopo Polvere, Simone Lucchesi, Chiara Coppola, Simone Costagli, Gabiria Pastore, Anna Sicuranza, Monica Tozzi, Arianna Lippi, Francesca Panza, Monica Bocchia, Alessandro Bucalossi, Guido Garosi, David Bennett, Sonia Bernazzali, Massimiliano Fabbiani, Francesca Montagnani, Donata Medaglini

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Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters by Yongjun Sui, Swagata Kar, Bhavna Chawla, Tanya Hoang, YuanKai Yu, Shannon M. Wallace, Hanne Andersen, Jay A. Berzofsky

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Jet Injection of Naked mRNA Encoding the RBD of the SARS-CoV-2 Spike Protein Induces a High Level of a Specific Immune Response in Mice by Denis N. Kisakov, Larisa I. Karpenko, Lyubov A. Kisakova, Sergey V. Sharabrin, Mariya B. Borgoyakova, Ekaterina V. Starostina, Oleg S. Taranov, Elena K. Ivleva, Oleg V. Pyankov, Anna V. Zaykovskaya, Elena V. Dmitrienko, Vladimir A. Yakovlev, Elena V. Tigeeva, Irina Alekseevna Bauer, Svetlana I. Krasnikova, Nadezhda B. Rudometova, Andrey P. Rudometov, Artemiy A. Sergeev, Alexander A. Ilyichev

Subjects: “…mRNA vaccines…”
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A Spike-Based mRNA Vaccine Encapsulated in Phospholipid 1,2-Dioleoyl-sn-Glycero-3-PhosphoEthanolamine Containing Lipid Nanoparticles Induced Potent B- and T-Cell Responses Associated with Protection Against SARS-CoV-2 Infection and COVID-19-like Symptoms in Hamsters by Afshana Quadiri, Swayam Prakash, Latifa Zayou, Nisha Rajeswari Dhanushkodi, Amruth Chilukuri, Gemma Ryan, Kelly Wang, Hawa Vahed, Aziz A. Chentoufi, Lbachir BenMohamed

“…Conclusion: This study suggests mRNA vaccines encapsulated in Phospholipid 1,2-Dioleoyl-sn-Glycero-3-PhosphoEthanolamine containing LNPs induced Potent B- and T cell immunity. …”
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Antibody Avidity and Neutralizing Response against SARS-CoV-2 Omicron Variant after Infection or Vaccination by Francesca Dapporto, Serena Marchi, Margherita Leonardi, Pietro Piu, Piero Lovreglio, Nicola Decaro, Nicola Buonvino, Angela Stufano, Eleonora Lorusso, Emilio Bombardieri, Antonella Ruello, Simonetta Viviani, Eleonora Molesti, Claudia Maria Trombetta, Alessandro Manenti, Emanuele Montomoli

“…Samples were collected from 42 SARS-CoV-2 infected patients during the first pandemic wave, 50 subjects who received 2 doses of mRNA vaccine before the Omicron wave, 44 subjects who received 3 doses of mRNA vaccine, and 35 subjects who received heterologous vaccination (2 doses of adenovirus-based vaccine plus mRNA vaccine) during the Omicron wave. …”
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A 20-Year-Old Man with IgA Vasculitis following COVID-19 Vaccination by Abdulaziz Alsubaie, Abdulmajeed Alshabanat, Abdulrahman Almizel, Mohammed Omair, Rahaf Alodaini

“…Herein, we report a case of a young man who is previously healthy and who developed IgA vasculitis after the first dose of the COVID-19 mRNA vaccine Pfizer-BioNTech. The patient’s symptoms were mainly skin and joint without renal or other system involvement. …”
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First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine by Yael Raviv, Batya Betesh-Abay, Yuliya Valdman-Grinshpoun, Liora Boehm-Cohen, Michael Kassirer, Iftach Sagy

“…There are scarcely reported cases of SLE development following COVID-19 mRNA vaccination. We present a case of a 24-year-old male without preexisting conditions or family history of autoimmune disorders, presenting with SLE following the first dose of the SARS-CoV-2 Pfizer-BioNTech mRNA vaccine.…”
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Nonviral targeted mRNA delivery: principles, progresses, and challenges by Xi He, Guohong Li, Letao Huang, Haixing Shi, Sha Zhong, Siyu Zhao, Xiangyu Jiao, Jinxiu Xin, Xiaoling Yin, Shengbin Liu, Zhongshan He, Mengran Guo, Chunli Yang, Zhaohui Jin, Jun Guo, Xiangrong Song

“…Abstract Messenger RNA (mRNA) therapeutics have garnered considerable attention due to their remarkable efficacy in the treatment of various diseases. The COVID‐19 mRNA vaccine and RSV mRNA vaccine have been approved on the market. …”
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Nanomédicaments pour le traitement de maladies graves et recherches duales by Couvreur, Patrick

“…They have also contributed to groundbreaking discoveries, including the introduction of the first mRNA vaccine (against COVID-19), and have improved certain imaging and diagnostic techniques, too. …”
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