Reproductive performance of female largemouth bass (Micropterus salmoides) broodstock was enhanced by dietary small peptides by Jie Wei, Mingwei Tao, Jiaming Huang, Hangxian Zhou, Qiyou Xu

“…The mRNA expression levels of vgr (1.90 ± 0.29), insulin-like growth factor-1 (1.53 ± 0.67), steroidogenic acute regulatory protein (2.59 ± 0.78), fshr (1.97 ± 0.35) and cyp17a (2.78 ± 1.32) in gonad were up-regulated in the HS group (P < 0.05). …”
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Interferon-γ Stimulates Monocyte Chemotactic Protein-1 Expression by Monocytes by J. M. Liebler, S. L. Kunkel, R. M. Allen, M. D. Burdick, R. M. Strieter

“…In contrast, stimulation with IFN-γ resulted in a dose dependent increase in MCP-1 protein and mRNA expression. Simultaneous stimulation with IFN-γ and IL-1β or TNF-α resulted in no further increase in MCP-1 production. …”
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Early Osteogenic Differentiation Stimulation of Dental Pulp Stem Cells by Calcitriol and Curcumin by Mohammad Samiei, Atefeh Abedi, Simin Sharifi, Solmaz Maleki Dizaj

“…Curcumin individually and in combination with calcitriol increased ALP activity and osteoblast-specific mRNA expression of ALP when DPSCs were cultured in an osteogenic medium. …”
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IL-4 induces cAMP and cGMP in human monocytic cells by B. Dugas, N. Paul-Eugene, K. Yamaoka, C. Amirand, C. Damais, J. P. Kolb

“…By RT-PCR, a type III constitutive NOS mRNA was detected in U937 monocytic cells. IL-4 also increased the [Ca2+]i in these cells. …”
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Comparative Effects of Sulforaphane and Allyl Isothiocyanate on 3T3-L1 Adipogenesis by Satoru Sakuma, Kana Yasuda, Risa Kitahara, Kaho Tsujimoto, Kishiko Yamashita, Naohiro Hoshino, Yohko Fujimoto, Keiichiro Okuhira

“…We found that, at a concentration as low as one-tenth that of allyl isothiocyanate, sulforaphane reduced triacylglycerol levels, lipid-filled adipocyte quantity, and mRNA and protein levels of CCAAT-enhancer-binding protein α (C/EBPα) and peroxisome proliferator-activated receptor γ (PPARγ). …”
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Toll-Like Receptors and Cytokines as Surrogate Biomarkers for Evaluating Vaginal Immune Response following Microbicide Administration by Sadhana M. Gupta, Clara C. Aranha, Madhu C. Mohanty, K. V. R. Reddy

“…The results revealed no alteration in the expression of TLRs and cytokines at both protein and mRNA levels. However, in SDS gel-treated group, the levels were significantly upregulated with the induction of NF-κB signalling cascade. …”
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Turnour necrosis factor stimulates endothelin-1 gene expression in cultured bovine endothelial cells by Silvia Orisio, Marina Morigi, Carla Zoja, Norberto Perico, Giuseppe Remuzzi

“…TNF-α (10 and 100 ng ml−1) increased in a time dependent manner the preproendothelin-1 mRNA levels in respect to unstimulated endothelial cells. …”
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OPTIMIZATION OF MEDICAL EVALUATION STRATEGIES IN VACCINATED WOMEN ANTI COVID-19, IN ROMANIA, TO IMPROVE THE LEVEL OF HESITATION AGAINST THE BENEFIT OF VACCINATION by Andreea Roxana Luca, Ramona Elena Teiu, Tudor Florin Ursuleanu, Roxana Grigorovici, Hlescu Cristian Stefan, Maria Paula Comanescu, Alina Ionela Calin, Alexandru Grigorovici

“…In December 2020, the first two mRNA vaccines, developed by Pfizer/BioNTech and Moderna, were approved by the FDA in the USA. …”
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Design of Nonfragile State Estimator for Discrete-Time Genetic Regulatory Networks Subject to Randomly Occurring Uncertainties and Time-Varying Delays by Yanfeng Zhao, Jihong Shen, Dongyan Chen

“…The focus of the paper is on developing a new nonfragile state estimation method to estimate the concentrations of the mRNA and the protein for considered uncertain delayed GRNs, where the randomly occurring estimator gain perturbations are allowed. …”
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Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases by Ya-Min Ma, Lan Zhao

“…They can inhibit translation or overexpression by combining with mRNA and participate in posttranscriptional regulation of genes, resulting in reduced expression of target proteins, affecting the development, growth, aging, metabolism, and other physiological and pathological processes of animals and plants. …”
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miR-214-3p Deficiency Enhances Caspase-1-Dependent Pyroptosis of Microglia in White Matter Injury by Liufang He, Tingyan Wei, Yong Huang, Xueli Zhang, Dongbo Zhu, Huazhen Liu, Zhangxing Wang

“…Treatment with miR-214-3p agomir is sufficient to relieve the white matter lesion and demyelination in WMI mice. miR-214-3p is able to bind to the 3′ region of the NLRP-3 inflammasome compartment NEK7, preventing the transcription of NEK7 mRNA. As a result, in WMI mice, the lack of miR-214-3p leads to the accumulation of NEK7 which supports NLRP 3 inflammasome activation, microglial pyroptosis, and white matter pathogenesis.…”
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Harnessing the Angiogenic Potential of Stem Cell-Derived Exosomes for Vascular Regeneration by F. Alcayaga-Miranda, M. Varas-Godoy, M. Khoury

“…Exosomes are key mediators of intercellular communication and contain a cargo that includes a modifiable content of microRNA (miRNA), mRNA, and proteins. Since the biogenesis of the MSCs-derived exosomes is regulated by the cross talk between MSCs and their niche, the content of the exosomes and consequently their biological function are dependent on the cell of origin and the physiologic or pathologic status of their microenvironment. …”
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Expression of Genes Encoding the Enzymes for Glycogen and Trehalose Metabolism in L3 and L4 Larvae of Anisakis simplex by E. Łopieńska-Biernat, E. A. Zaobidna, M. Dmitryjuk

“…The aim of this study was to investigate the expression of genes encoding the enzymes involved in the metabolism of trehalose and glycogen—trehalose-6-phosphate synthase (TPS), trehalose-6-phosphate phosphatase (TPP), glycogen synthase (GS), and glycogen phosphorylase (GP)—in stage L3 and stage L4 larvae of A. simplex. The expression of mRNA all four genes, tps, tpp, gs, and gp, was examined by real-time polymerase chain reaction. …”
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In Vivo Exposure of Deltamethrin Dysregulates the NFAT Signalling Pathway and Induces Lung Damage by Prakriti Sharma, R. S. Sethi

“…The lung samples were extracted from the Swiss albino mice following the treatment of low (2.5 mg/kg) and high (5 mg/kg) doses of deltamethrin. The mRNA expression of TCR, IL-4, and IL-13 showed upregulation, while the expression of NFAT and FOS was downregulated following a low dose of deltamethrin. …”
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FBXW7 metabolic reprogramming inhibits the development of colon cancer by down-regulating the activity of arginine/mToR pathways. by Qing Li, Yan Li, Tong Zhou, Yong Zhang, Huiyu Li, Fajia Yuan, Yanghui Bi

“…Low expression of FBXW7 was associated with poor prognosis in individuals with CRC, both at the mRNA and protein levels. FBXW7 over-expression inhibited CRC cell growth, colony formation, migration, and invasion. …”
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Interleukin-6 stimulates gene expression of extracellular matrix components in bovine mesangial cells in culture by C. Zoja, A. Benigni, G. Piccinini, M. Figliuzzi, L. Longaretti, G. Remuzzi

“…In contrast, IL-6 stimulated laminin mRNA expression only after 48 h incubation (2.5-fold upon basal level). …”
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The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degener... by Lisa Schwarz, Grit Vollmer, Christiane Richter-Landsberg

“…Microarray and immunoblot analysis revealed that HSP27 is enhanced at the mRNA and protein levels in affected brains, and that it is associated with astrocytic pathology. …”
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Production of Secretory Leucocyte Protease Inhibitor (SLPI) in Human Pancreatic β-Cells by Max Nyström, Magnus Bergenfeldt, Irena Ljungcrantz, Èsa Lindeheim, Kjell Ohlsson

“…Since SLPI is an inhibitor of pancreatic proteases we wished to investigate whether SLPI was also actually produced in the pancreas. M-RNA from human pancreatic tissue showed evidence of SLPI production using the reverse transcriptase polymer chain reaction technique (RTPCR). …”
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Recombinant Adenovirus siRNA Knocking Down the Ndufs4 Gene Alleviates Myocardial Apoptosis Induced by Oxidative Stress Injury by Beibei Wang, Jinsheng Zhang, Aijun Xu

“…The results showed that the adenovirus infection rate was about 90%, and Ndufs4 mRNA and protein were decreased by 76.7% and 64.9%, respectively. …”
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Fluo-Cast-Bright: a deep learning pipeline for the non-invasive prediction of chromatin structure and developmental potential in live oocytes by Xiangyu Zhang, Claudia Baumann, Rabindranath De La Fuente

“…Importantly, transcriptome analysis following non-invasive selection revealed that meiotically competent oocytes exhibit a higher expression of transcripts associated with RNA and protein nuclear export, maternal mRNA deadenylation, histone modifications, chromatin remodeling and signaling pathways regulating microtubule dynamics during the metaphase-I to metaphase-II transition. …”
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