Identification of robust and abundant reference transcripts for EV mRNA cargo normalization by Antje M. Zickler, Radosław Grochowski, André Görgens, Erik Bäcklin, Maximilian Kordes, J.-Matthias Löhr, Joel Z. Nordin, Samir EL Andaloussi, Daniel W. Hagey

Subjects: Get full text

SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency by Brendan Connolly, Cleo Isaacs, Lei Cheng, Kirtika H. Asrani, Romesh R. Subramanian

“…Taken together, our data suggests that SerpinA1 mRNA therapy has the potential to benefit patients suffering from AAT deficiency.…”
Get full text

Mechanism of modified mRNA structure in COVID-19 vaccines for inducing neutralizing antibodies by Sabighoh Zanjabila, Beti Ernawati Dewi

Subjects: “…mRNA vaccine…”
Get full text

Reduced UPF1 levels in senescence impair nonsense-mediated mRNA decay by Dahyeon Koh, Yebin Lee, Kyuchan Kim, Hyeong Bin Jeon, Chaehwan Oh, Sangik Hwang, Minjung Lim, Kwang-Pyo Lee, Yeonkyoung Park, Yong Ryoul Yang, Yoon Ki Kim, Donghwan Shim, Myriam Gorospe, Ji Heon Noh, Kyoung Mi Kim

“…These findings suggest that the decline in UPF1 levels during cellular senescence accelerates the senescent phenotype by impairing NMD activity and the consequent accumulation of abnormal mRNA.…”
Get full text

Developing mRNA lipid nanoparticle vaccine effective for cryptococcosis in a murine model by Yeqi Li, Suresh Ambati, Richard B. Meagher, Xiaorong Lin

“…These results support the promise of mRNA-LNP vaccines against fungal diseases.…”
Get full text

Significant Cytokine mRNA Expression Changes Immediately after Initiation of Cardiopulmonary Resuscitation by Mareen Braunstein, Martina Williamson, Thomas Kusmenkov, Jürgen Landes, Peter Biberthaler, Karl-Georg Kanz, Wolfgang Böcker, Viktoria Bogner

“…IL-1ra mRNA levels significantly increased beginning after 6 h. …”
Get full text

Translational inhalable extracellular vesicle‐based mRNA therapy for the treatment of lung cancer by Mengrui Liu, Brian Henick, Ke Cheng

Get full text

Local delivery of TGF-β1-mRNA decreases fibrosis in osteochondral defects by Gianluca Fontana, Brett Nemke, Yan Lu, Connie Chamberlain, Jae-Sung Lee, Joshua A. Choe, Hongli Jiao, Michael Nelson, Margot Amitrano, Wan-Ju Li, Mark Markel, William L. Murphy

Subjects: Get full text

Decreases in mRNA by an siRNA Complex Do not Alter Blood Pressure in Mice by Su-Min Ji, Young-Bin Shin, So-Yon Park, Hyeon-Ju Lee, Bermseok Oh

“…To validate the function of CASZ1 in blood pressure, we decreased Casz1 mRNA levels in mice by siRNA. Casz1 siRNA reduced mRNA levels by 59% in a mouse cell line. …”
Get full text

Modification of Cɛ mRNA Expression by EBV-Encoded Latent Membrane Protein 1 by Kazuhiko Hanashiro, Shigeto Ohta, Masanori Sunagawa, Mariko Nakamura, Mikio Suzuki, Tadayoshi Kosugi

“…To evaluate the effect of expression of latent membrane protein (LMP) 1 encoded by Epstein-Barr virus (EBV) on Cɛ mRNA expression, mRNA levels were examined by RT-PCR or Northern blot analysis upon transient transfection of LMP1 in the splenocytes derived from Brown-Norway rats with or without immunization with 2,4-dinitrophenyl-conjugated Ascaris suum antigen. …”
Get full text

Acute myocarditis after the third dose of COVID‐19 mRNA‐1273 vaccine by Takayuki Yamada

Get full text

Downregulated mRNA Expression of ZNF385B Is an Independent Predictor of Breast Cancer by Ning Yan, Cong Liu, Fang Tian, Ling Wang, Yimin Wang, Zhaoying Yang, Yan Jiao, Miao He

Get full text

Development and Evaluation of the Immunogenic Potential of an Unmodified Nucleoside mRNA Vaccine for Herpes Zoster by Shun Zhang, Xiaojie Wang, Tongyi Zhao, Chen Yang, Lulu Huang

Subjects: Get full text

EGR1 mRNA expression levels and polymorphisms are associated with slaughter performance in chickens by Mao Ye, Xiaohuan Chao, Chutian Ye, Lijin Guo, Zhexia Fan, Xuerong Ma, Aijun Liu, Weiming Liang, Shuya Chen, Cheng Fang, Xiquan Zhang, Qingbin Luo

Get full text

Identification of Potential miRNA-mRNA Regulatory Network Contributing to Parkinson’s Disease by Xi Yin, Miao Wang, Wei Wang, Tong Chen, Ge Song, Yixuan Niu, Ziying Jiang, Zhongbao Gao, Zhenfu Wang

“…This study aimed to explore the miRNA-mRNA regulatory network for PD. The differentially expressed miRNAs (DEmis) and genes (DEGs) between PD patients and healthy donors were screened from the miRNA dataset GSE16658 and mRNA dataset GSE100054 downloaded from the Gene Expression Omnibus (GEO) database. …”
Get full text

tRNA/mRNA Mimicry by tmRNA and SmpB in Trans-Translation by Daisuke Kurita, Akira Muto, Hyouta Himeno

“…Since accurate translation from mRNA to protein is critical to survival, cells have developed translational quality control systems. …”
Get full text

Chlamydia trachomatis Growth and Cytokine mRNA Response in a Prostate Cancer Cell Line by Ivan M. Petyaev, Naylia A. Zigangirova, Elena Y. Morgunova, Nigel H. Kyle, Elena D. Fedina, Yuriy K. Bashmakov

“…In the present paper, we report that C. trachomatis can be efficiently propagated and affect mRNA expression for two major cytokines, relevant to tumor progression, in CWR-R1 cells, a malignant prostate cell line. …”
Get full text

Differential Expression Profiling of Long Noncoding RNA and mRNA during Osteoblast Differentiation in Mouse by Minjung Kim, Youngseok Yu, Ji-Hoi Moon, InSong Koh, Jae-Hyung Lee

“…We also identified 72 mRNA and 89 lncRNAs as potential markers including several novel markers for osteoblast differentiation and activation. …”
Get full text

The mRNA-1647 vaccine: A promising step toward the prevention of cytomegalovirus infection (CMV) by Adewunmi Akingbola, Abiodun Adegbesan, Olajumoke Adewole, Kolade Adegoke, Akpevwe Emmanuella Benson, Paul Ayomide Jombo, Sandra Uchechukwu Eboson, Victor Oluwasola, Ademola Aiyenuro

Subjects: Get full text

Peripheral Mononuclear Cell Resistin mRNA Expression Is Increased in Type 2 Diabetic Women by Panayoula C. Tsiotra, Constantine Tsigos, Eleni Anastasiou, Eleni Yfanti, Eleni Boutati, Emmanouil Souvatzoglou, Ioannis Kyrou, Sotirios A. Raptis

“…Resistin mRNA levels were easily detectable in human PBMC, and found to be higher in DM2 compared to healthy women (P=.05). …”
Get full text