Showing 41 - 60 results of 105 for search '"mAbs"', query time: 0.06s Refine Results
  1. 41
    GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models

    GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models by Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin

    Published 2024-12-01
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  2. 42
    Development of a novel, high-throughput imaged capillary isoelectric focusing-Western method to characterize charge heterogeneity of monoclonal antibody heavy and light chains

    Development of a novel, high-throughput imaged capillary isoelectric focusing-Western method to characterize charge heterogeneity of monoclonal antibody heavy and light chains by Gangadhar Dhulipala, Alanna Broszeit, Kun Lu, Nisha Palackal, Erica Pyles

    Published 2024-12-01
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  3. 43
    IL-2-armored peptide-major histocompatibility class I bispecific antibodies redirect antiviral effector memory CD8+ T cells to induce potent anti-cancer cytotoxic activity with limited cytokine release

    IL-2-armored peptide-major histocompatibility class I bispecific antibodies redirect antiviral effector memory CD8+ T cells to induce potent anti-cancer cytotoxic activity with lim... by John S. Schardt, Even Walseng, Kim Le, Chunning Yang, Pooja Shah, Ying Fu, Kausar Alam, Cathryn R. Kelton, Yu Gu, Fengying Huang, Jia Lin, Wenhai Liu, Andrew Dippel, Hanzhi Zhang, Kathy Mulgrew, Stacy Pryts, Vijaykumar Chennupati, Hung-Chang Chen, Jessica Denham, Xiaoru Chen, Pallab Pradhan, Yuling Wu, Colin Hardman, Chihao Zhao, Michael Kierny, Yang Song, Simon J. Dovedi, Saso Cemerski, Yariv Mazor

    Published 2024-12-01
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  4. 44
    Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors

    Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors by Geoff Hale, Jelle De Vos, Alastair Douglas Davy, Koen Sandra, Ian Wilkinson

    Published 2024-12-01
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  5. 45
    Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains

    Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains by Lewis Chinery, Jeliazko R. Jeliazkov, Charlotte M. Deane

    Published 2024-12-01
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  6. 46
    Multivariate quantitative analysis of glycan impact on IgG1 effector functions

    Multivariate quantitative analysis of glycan impact on IgG1 effector functions by Tamara Cvijić, Matej Horvat, Jakob Plahutnik, Ana Golob, Jaka Marušič

    Published 2024-12-01
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  7. 47
    Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study

    Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study by Jennifer Moore, Alicia Aylott, Wen-Hung Chen, Jerzy Daniluk, Ian A. Hawes, Sergio Parra, Prosenjit Sarkar, Yasmin Sanchez-Pearson, Megan Turner, Amanda Peppercorn, Andrew Skingsley

    Published 2025-12-01
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  8. 48
    Electrostatic properties of human germlines and biodistribution of small biologics

    Electrostatic properties of human germlines and biodistribution of small biologics by Leticia Maria De Souza Cordeiro, Kelley Christine Atkinson, Argin Aivazian, Patrick Frank Joyce, Fang Jia, Alessandro Mascioni

    Published 2024-12-01
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  9. 49
    Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration

    Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration by Paul Tamburini, Dennis Vestergaard Pedersen, Denise Devore, Josh Cone, Rekha Patel, Todd Hunter, Fang Sun, Gregers Rom Andersen, Jeffrey Hunter

    Published 2024-12-01
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  10. 50
    Biparatopic binding of ISB 1442 to CD38 in trans enables increased cell antibody density and increased avidity

    Biparatopic binding of ISB 1442 to CD38 in trans enables increased cell antibody density and increased avidity by Jeremy Loyau, Thierry Monney, Marco Montefiori, Fedir Bokhovchuk, Jeremy Streuli, Matthew Blackburn, Arnaud Goepfert, Lydia N. Caro, Samitabh Chakraborti, Stefania De Angelis, Camille Grandclément, Stanislas Blein, M. Lamine Mbow, Ankita Srivastava, Mario Perro, Stefano Sammicheli, Eugene A. Zhukovsky, Michael Dyson, Cyrille Dreyfus

    Published 2025-12-01
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  11. 51
    Antibodies to watch in 2024

    Antibodies to watch in 2024 by Silvia Crescioli, Hélène Kaplon, Alicia Chenoweth, Lin Wang, Jyothsna Visweswaraiah, Janice M. Reichert

    Published 2024-12-01
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  12. 52
    Navigating large-volume subcutaneous injections of biopharmaceuticals: a systematic review of clinical pipelines and approved products

    Navigating large-volume subcutaneous injections of biopharmaceuticals: a systematic review of clinical pipelines and approved products by Philip Green, Andreas Schneider, Jakob Lange

    Published 2024-12-01
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  13. 53
    Large-scale data mining of four billion human antibody variable regions reveals convergence between therapeutic and natural antibodies that constrains search space for biologics drug discovery

    Large-scale data mining of four billion human antibody variable regions reveals convergence between therapeutic and natural antibodies that constrains search space for biologics dr... by Pawel Dudzic, Dawid Chomicz, Jarosław Kończak, Tadeusz Satława, Bartosz Janusz, Sonia Wrobel, Tomasz Gawłowski, Igor Jaszczyszyn, Weronika Bielska, Samuel Demharter, Roberto Spreafico, Lukas Schulte, Kyle Martin, Stephen R. Comeau, Konrad Krawczyk

    Published 2024-12-01
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  14. 54
    Anti-HER2 biparatopic antibody KJ015 has near-native structure, functional balanced high affinity, and synergistic efficacy with anti-PD-1 treatment in vivo

    Anti-HER2 biparatopic antibody KJ015 has near-native structure, functional balanced high affinity, and synergistic efficacy with anti-PD-1 treatment in vivo by Zheng Wang, Yu Liu, Yunxia Xu, Lin Lu, Zhen Zhu, Baojie Lv, Xin Fang, Yao Tang, Jinhua Wang, Yu Cheng, Ying Hu, Junwen Lou, Peican Wu, Chendan Liu, Yanjun Liu, Xin Zeng, Qing Xu

    Published 2024-12-01
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  15. 55
    A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy

    A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

    Published 2024-12-01
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  16. 56
    Decoding the mannose receptor-mAb interaction: the importance of high-mannose N-glycans and glycan-pairing

    Decoding the mannose receptor-mAb interaction: the importance of high-mannose N-glycans and glycan-pairing by Julia Baumeister, Maximilian Meudt, Sybille Ebert, Frank Rosenau, Boris Mizaikoff, Michaela Blech, Kristina M. J. Aertker, Fabian Higel

    Published 2024-12-01
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  17. 57
    Can antibodies be “vegan”? A guide through the maze of today’s antibody generation methods

    Can antibodies be “vegan”? A guide through the maze of today’s antibody generation methods by Stefan Dübel

    Published 2024-12-01
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  18. 58
    Evaluation of the impact of antibody fragments on aggregation of intact molecules via size exclusion chromatography coupled with native mass spectrometry

    Evaluation of the impact of antibody fragments on aggregation of intact molecules via size exclusion chromatography coupled with native mass spectrometry by Jing Xu, John E. Coughlin, Malgorzata Szyjka, Serene Jabary, Sonal Saluja, Zoran Sosic, Yunqiu Chen, Chong-Feng Xu

    Published 2024-12-01
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  19. 59
    Antibody association in solution: cluster distributions and mechanisms

    Antibody association in solution: cluster distributions and mechanisms by Sandi Brudar, Leonid Breydo, Elisha Chung, Ken A. Dill, Nasim Ehterami, Ketan Phadnis, Samir Senapati, Mohammed Shameem, Xiaolin Tang, Muhammmad Tayyab, Barbara Hribar-Lee

    Published 2024-12-01
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  20. 60
    In-situ biophysical characterization of high-concentration protein formulations using wNMR

    In-situ biophysical characterization of high-concentration protein formulations using wNMR by Jing Song, Marc Taraban, Y. Bruce Yu, Lynn Lu, Pallavi Guha Biswas, Wei Xu, Hanmi Xi, Akhilesh Bhambhani, Guangli Hu, Yongchao Su

    Published 2024-12-01
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