TFEB overexpression alleviates autophagy-lysosomal deficits caused by progranulin insufficiency by Wren O. Nader, Kaylan S. Brown, Nicholas R. Boyle, Azariah K. Kaplelach, Shaimaa M. Abdelaziz, Skylar E. Davis, Qays Aljabi, Ahmad R. Hakim, Amelia G. Davidson, Giacynta A. Vollmer, Leah C. Wright, J. Bailey Echols, Joelle Saad, Nicholas S. Pena, Andrew E. Arrant

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Lysosome-Mitochondrial Crosstalk in Cellular Stress and Disease by Szilvia Kiraly, Jack Stanley, Emily R. Eden

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Mucopolysachharidosis-II: A Rare Case Report by Kalgi Baxi, Ashish Jagati, Pooja Agarwal

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Mucopolysachharidosis-II: A Rare Case Report by Kalgi Baxi, Ashish Jagati, Pooja Agarwal

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Deciphering tuberculosis: lysosome-centric insights into pathogenesis and therapies by Cui Bao, Cui Bao, Yuanyuan Zhang, Yuanyuan Zhang, Jiao Feng, Jiao Feng, Xiuwen Hong, Xiuwen Hong, Nan Gao, Nan Gao, Ganzhu Feng

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Induced mitochondrial deficit by NDUFS3 transient silencing reduces RAB7 expression and causes lysosomal dysfunction in pancreatic cancer cells by Giulia Girolimetti, Sinforosa Gagliardi, Paola Cordella, Grazia Bramato, Riccardo Di Corato, Roberta Romano, Flora Guerra, Cecilia Bucci

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Construction of Triphenylamine-Based Aggregation-Induced Emission Luminogens for Lysosomes Imaging and Its Application in the Photodynamic Therapy of Cancer Cells by Zhanguo Sun, Bin Liu, Huijun Liu

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The rapidly evolving view of lysosomal storage diseases by Giancarlo Parenti, Diego L Medina, Andrea Ballabio

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Inhibition and evasion of neutrophil microbicidal responses by Legionella longbeachae by Hannah E. Hanford, Christopher T. D. Price, Silvia Uriarte, Yousef Abu Kwaik

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Caricain: A basis for enzyme therapy for coeliac disease by Hugh Cornell, Teodor Stelmasiak

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Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism by Or Kakhlon, Hilla Vaknin, Kumudesh Mishra, Jeevitha D’Souza, Monzer Marisat, Uri Sprecher, Shane Wald‐Altman, Anna Dukhovny, Yuval Raviv, Benny Da’adoosh, Hamutal Engel, Sandrine Benhamron, Keren Nitzan, Sahar Sweetat, Anna Permyakova, Anat Mordechai, Hasan Orhan Akman, Hanna Rosenmann, Alexander Lossos, Joseph Tam, Berge A. Minassian, Miguel Weil

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Granular Cell Transformation in Plexiform Ameloblastoma: Case Report and Literature Review by Aravindan S, Nikita Kashyap, Saharsh Sarawgi, Sudipta Rakshit, Srihari S, Suchitra Kisku

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Increased expression of the small lysosomal gene SVIP in the Drosophila gut suppresses pathophysiological features associated with a high-fat diet by Brennan M. Mercola, Tatiana V. Villalobos, Jocelyn E. Wood, Ankita Basu, Alyssa E. Johnson

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Naringenin and SMER28 target lysosomal reformation and rescue SPG11 and SPG15 hereditary spastic paraplegia phenotypes by Chiara Vantaggiato, Giulia Guarato, Francesca Brivio, Elena Panzeri, Beatrice Speltoni, Sentiljana Gumeni, Genny Orso, Filippo Maria Santorelli, Maria Teresa Bassi

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ESCRT III Regulates Lysosomal Perinuclear Clustering by Inhibiting Kinesin 1 Leading to Agnps Cytotoxicity in Human Cells by Tiantian Liu, Aiguo Xie, Chao Xing, RuiZhe He, Wei Ni, Yinbo Peng, Peng Xu, Yong Fang

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Identification of presenilin mutations that have sufficient gamma-secretase proteolytic activity to mediate Notch signaling but disrupt organelle and neuronal health by Zahra Ashkavand, Kerry C. Ryan, Jocelyn T. Laboy, Ritika Patel, Brian Geller, Kenneth R. Norman

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Metabolic and Structural Consequences of GM3 Synthase Deficiency: Insights from an HEK293-T Knockout Model by Elena Chiricozzi, Giulia Lunghi, Manuela Valsecchi, Emma Veronica Carsana, Rosaria Bassi, Erika Di Biase, Dorina Dobi, Maria Grazia Ciampa, Laura Mauri, Massimo Aureli, Kei-ichiro Inamori, Jin-ichi Inokuchi, Sandro Sonnino, Maria Fazzari

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A β‐galactosidase activated near‐infrared fluorescent probe for tracking cellular senescence in vitro and in vivo by Tian Su, Ruijun Shen, Dengchu Tu, Xiaoyue Han, Xianzhu Luo, Fabiao Yu

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PTEN deficiency in postnatally developing Purkinje cells disrupts metabolic signaling, leading to dendritic abnormalities and sex-specific behavioral deficits by Lindsay J. Walsh, Izabella M. Espinal-San Miguel, Ana V. Rodriguez, Ursula M. Peña, Kiley E. Flynn, Will C. Remillard, Siena R. Brazier, Natalia I. Anderson, Aidan J. Clark, Tiffany A. De Varona, Ileana Soto

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Engine breakdown of lysosomes and related organelles and the resulting physiology by Nina Bakker, Marlieke L. M. Jongsma, Jacques Neefjes

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