Purple Urine Bag Syndrome in Two Elderly Men with Urinary Tract Infection by Jan Van Keer, Daan Detroyer, Bert Bammens

“…The first patient is an 81-year-old man who was hospitalized for a newly diagnosed lymphoma with acute obstructive renal failure for which a nephrostomy procedure was performed. …”
Get full text

Long term efficacy and safety of Lorlatinib in ALK-positive non-small cell lung cancer: A case report by Jialin Qian, Tianqing Chu

“…Background: Anaplastic lymphoma kinase (ALK) rearrangement is a key oncogenic driver promoting the expression of ALK protein in non-small cell lung cancer (NSCLC). …”
Get full text

Solitary Pulmonary Nodule: A Diagnostic Dilemma by Pardeep Masuta, Ioana Amzuta

“…Initial biopsies of the nodule suggested follicular lymphoma, but after obtaining more tissue, the pathology was negative for malignancy and instead showed necrotizing pneumonia. …”
Get full text

Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis by Giorgio Berlot, Ariella Tomasini, Lorenzo Zandonà, Eugenio Leonardo, Rossana Bussani, Nadia Zarrillo

“…At the autopsy, an extremely uncommon aggressive lymphoma of Epstein-Barr virus-positive T-lymphocytes with systemic involvement was discovered.…”
Get full text

Anterior Mediastinal Mass: A Rare Presentation of Tuberculosis by Gopi C. Khilnani, Neetu Jain, Vijay Hadda, Sudheer K. Arava

“…The possibilities of lymphoma or germ cell tumour were considered. A biopsy from the mass under CT guidance was performed. …”
Get full text

Association of age, race, and ethnicity with access, response, and toxicities from CAR-T therapy in children and adults with B-cell malignancies: a review by Marco Ruella, Guido Ghilardi, Zainul S. Hasanali, Sandra P. Susanibar-Adaniya, Lena E. Winestone, Alfred L. Garfall

“…We focus on B-cell acute lymphoblastic leukemia, B-cell non-Hodgkin’s lymphoma, and multiple myeloma.…”
Get full text

A review on the potential of Bruton’s tyrosine kinase (Btk) inhibitor – Ibrutinib for treatment of Multiple Myeloma (MM) by Sze-Ting Bong, Lydia Ngiik-Shiew Law, Jodi Woan-Fei Law

“…Ibrutinib is a highly selective irreversible Btk inhibitor commonly used as treatment for B-cell malignancies such as Mantle Cell Lymphoma (MCL) and Chronic Lymphocytic Leukemia (CLL). …”
Get full text

How Reproducible Is Bioluminescent Imaging of Tumor Cell Growth? Single Time Point versus the Dynamic Measurement Approach by Shingo Baba, Steve Y. Cho, Zhaohui Ye, Linzhao Cheng, James M. Engles, Richard L. Wahl

“…To determine the most robust and reproducible parameters for noninvasively estimating tumor cell burden in a murine model, we used real-time in vivo bioluminescent imaging to assess the growth kinetics and dissemination of luciferase-transfected Raji B-cell lymphoma. Bioluminescent signals were acquired every minute for 40 minutes after luciferin injection every other day post-tumor injection. …”
Get full text

Monoclonal Antibodies Conjugated with Superparamagnetic Iron Oxide Particles Allow Magnetic Resonance Imaging Detection of Lymphocytes in the Mouse Brain by Alessandro Luchetti, Davide Milani, Francesca Ruffini, Rossella Galli, Andrea Falini, Angelo Quattrini, Giuseppe Scotti, Giancarlo Comi, Gianvito Martino, Roberto Furlan, Letterio S. Politi

“…We successfully employed vectorialized SPIO particles to image B220 + cells in a murine model of B-cell lymphoma. Likewise, we were able to identify CD3 + infiltrates in a murine model of multiple sclerosis. …”
Get full text

Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Trac... by Saad Qadwai, Tayyaba Rehman, Jonathan Barsa, Zeeshan Solangi, Edward Lebovics

“…Hepatitis C virus (HCV) is known for its oncogenic potential and has been found to be associated with hepatocellular carcinoma (HCC) and non-Hodgkin lymphoma. It has also been postulated that HCV may play a role in the development of other extrahepatic solid tumors of other organs of the body since it has been isolated from the vessel wall, kidney, and oral mucosa. …”
Get full text

Research Progress on Metabolic Regulation of Lysosomes and Their Regulatory Mechanism on Meat Tenderness by DONG Yushan, DU Rui, SU Rina, YAO Lili, DU Xuerong, LI Chenlong, WU Junqin, HOU Yanru, LUO Yulong

“…This article introduces the action mechanism and metabolic processes of lysosomes and elaborates the activation pathways of lysosomal membrane permeabilization through reactive oxygen species (ROS), sphingosine, B-cell lymphoma-2 (Bcl-2) and p53 proteins. Furthermore, it explores the pathway for the involvement of lysosomes in apoptosis, and summarizes the regulatory mechanism of lysosomes on muscle tenderization from the perspectives of the release of cathepsins and Ca2+, caspase activation and iron-induced oxidative stress. …”
Get full text

Obesity as a Major Risk Factor for Cancer by Giovanni De Pergola, Franco Silvestris

“…Reports from the International Agency for Research into Cancer and the World Cancer Research Fund (WCRF) have shown that the strongest evidence exists for an association of obesity with the following cancer types: endometrial, esophageal adenocarcinoma, colorectal, postmenopausal breast, prostate, and renal, whereas the less common malignancies are leukemia, non-Hodgkin’s lymphoma, multiple myeloma, malignant melanoma, and thyroid tumours. …”
Get full text

A New Challenging Strategy in the Prevention and Management of Tumor Lysis Syndrome in Patients with Chemo-Sensitive Hematological Malignancies by Ammar ELJack, Mohamad El Abdallah, Kadhim Al-Banaa, Kashif Chaudhry, Faisal Musa

“…We present a 24-year-old male patient with Burkitt’s lymphoma. After receiving one cycle therapy, he developed severe kidney injury from TLS. …”
Get full text

Solitary Lytic Bone Metastasis: A Rare Presentation of Small Lymphocytic Leukemia by Heather Katz, Steven Sagun, Doreen Griswold, Mohamed Alsharedi

“…Chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) is a hematologic malignancy characterized by an over accumulation of incompetent neoplastic lymphocytes. …”
Get full text

Pneumocystis carinii: A Review of an Important Opportunistic Pathogen in AIDS by M John Gill, Ron Read

“…Individuals with damaged T helper cells secondary to malignancies (eg, Hodgkin’s lymphoma), drugs (eg, cyclosporine, steroids), or certain infections (eg, human immunodeficiency virus) are at particular risk. …”
Get full text

Long-Term Follow-Up in Children with Anisocoria: Cocaine Test Results and Patient Outcome by Fabienne C. Fierz, Christina Gerth-Kahlert

“…Mediastinal Hodgkin lymphoma was found in one patient with an inconclusive cocaine test result. …”
Get full text

Pneumocystis Pneumonia Presenting as an Enlarging Solitary Pulmonary Nodule by Krunal Bharat Patel, James Benjamin Gleason, Maria Julia Diacovo, Nydia Martinez-Galvez

“…We report a case of a single nodular granulomatous Pneumocystis pneumonia in a male with diffuse large B-cell lymphoma after R-CHOP therapy. He presented with symptoms of productive cough, dyspnea, and right-sided pleuritic chest pain that failed to resolve despite treatment with multiple antibiotics. …”
Get full text

Silicone-Induced Granuloma of Breast Implant Capsule (SIGBIC): Histopathology and Radiological Correlation by Eduardo de Faria Castro Fleury, Gabriel Salum D’Alessandro, Sheila Cristina Lordelo Wludarski

“…Currently, attention has been given to complications related to breast implants, especially due to the presence of anaplastic large cell lymphoma (ALCL) related to silicone implants. Many manuscripts attempt to associate silicone presence with clinical complaints reported by patients, while others try to demonstrate the mechanisms of silicone bleeding by permeability loss of breast implant surfaces. …”
Get full text

Severe Erosive Pill Esophagitis Induced by Crizotinib Therapy: A Case Report and Literature Review by Patrick Jung, Kyle J. Fortinsky, Zane R. Gallinger, Piero Tartaro

“…Previous case reports have described esophagitis thought to be secondary to crizotinib, an oral tyrosine-kinase inhibitor used in the treatment of anaplastic lymphoma kinase- (ALK-) positive non-small cell lung cancer (NSCLC). …”
Get full text

Blocking Type I Interferon Production: A New Therapeutic Option to Reduce the HIV-1-Induced Immune Activation by Moritz Ries, Kathrin Pritschet, Barbara Schmidt

“…In this respect, the prevalence of Epstein-Barr virus-associated Hodgkin lymphoma and human papillomavirus-related anal neoplasia is rising in aging HIV-1-infected individuals despite antiretroviral therapy. …”
Get full text