An Unusual Case of Kidney Injury in a Young Woman with a Connective Tissue Disease by Roberto Rivera, Salvador Vila

“…A diagnosis of systemic lupus erythematosus was made. Due to recalcitrant thrombocytopenia, serositis, and renal insufficiency methylprednisolone was prescribed in high doses. …”
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Classification, Mechanisms of Action, and Therapeutic Applications of Inhibitory Oligonucleotides for Toll-Like Receptors (TLR) 7 and 9 by Petar S. Lenert

“…Several short ODNs have already shown promise as pathway-specific therapeutics for animal lupus. We envision their future use in human SLE, microbial DNA-dependent sepsis, and in other autoinflammatory diseases.…”
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Visual and somatosensory evoked potentials abnormalities among Behçet’s disease patients and their relation to disease activity, severity and antiphospholipid antibodies: a cross-s... by Ghada S. Nageeb, Enass A. Eliwa, Ibrahim Tharwat, Lamiaa A. Mohammad, Nada Alaa Attia

“…Vascular involvement was significantly associated with elevated lupus anticoagulant and anti-cardiolipin IgM antibodies (P < 0.05), elevated lupus anticoagulant levels were associated with optic nerve involvement and abnormal VEP. …”
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The Microbiome in Connective Tissue Diseases and Vasculitides: An Updated Narrative Review by Rossella Talotta, Fabiola Atzeni, Maria Chiara Ditto, Maria Chiara Gerardi, Piercarlo Sarzi-Puttini

“…The PubMed database was searched for articles using combinations of words or terms that included systemic lupus erythematosus, systemic sclerosis, autoimmune myositis, Sjögren’s syndrome, undifferentiated and mixed CTD, vasculitis, microbiota, microbiome, and dysbiosis. …”
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SLE and Non-Hodgkin’s Lymphoma: A Case Series and Review of the Literature by Prajwal Boddu, Abdul S. Mohammed, Chandrahasa Annem, Winston Sequeira

“…Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder punctuated by varied multiorgan complications all along the course of its natural history. …”
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Rheumatoid Arthritis and Autoimmune Hemolytic Anemia as First Manifestation of Rhupus by Alejandra Espinosa-Orantes, Martha Adriana Hernandez-Vera, Jose Daniel Juarez-Villa, Gutiérrez-Espinoza Anahí Guadalupe, Guillermo Flores

“…“Rhupus” syndrome is a rare condition that describes the coexistence of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), which prevalence among patients with SLE varies from 0.01% to 9.7%. …”
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Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the Literature by Arnaldo Toffon, Raffaella Piovesan, Consolato Francesco Minniti, Omar Caruso, Paolo Criscenti, Sabina Villalta, Maurizio Cavallo

“…The first group is called lupus anticoagulant and consists of immunoglobulins that inhibit the phospholipid dependent coagulation tests in vitro. …”
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CXCL13 Promotes Proliferation of Mesangial Cells by Combination with CXCR5 in SLE by Zhanyun Da, Liuxia Li, Jin Zhu, Zhifeng Gu, Bo You, Ying Shan, Si Shi

“…As a CXC subtype member of the chemokine superfamily, CXCL13 is considered to be involved in systemic lupus erythematosus (SLE), especially in lupus nephritis (LN). …”
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Cytokines and Cytokine Profiles in Human Autoimmune Diseases and Animal Models of Autoimmunity by Manfred Kunz, Saleh M. Ibrahim

“…In systemic lupus erythematosus, a so-called interferon signature has been identified. …”
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Cerebral Venous Thrombosis Mimicking a Discrete Brain Mass: A Case Report and Literature Review by Dana DiRenzo, Zsuzsanna H. McMahan, Naman S. Desai, Rebecca Manno, Michelle Petri

“…The differential diagnosis for a focal brain lesion in a patient with systemic lupus erythematosus (SLE) is broad and includes infection, malignancy, and vascular and inflammatory etiologies. …”
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Genetic Selection Pressure on TLR9 Gene Increases Individual Susceptibility to Systemic Inflammatory Disease: A Case Study of Kano State Population by Yusuf Jibril Habib, Mohammed Sani Jaafaru

“…This is thought to be the outcome of interactions among genetic factors and the terrain. Systemic lupus erythematosus (SLE) and other autoimmune disorders have been linked to this genetic plasticity. …”
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Hydroxychloroquine and Fabry Disease: Three Case Reports Examining an Unexpected Pathologic Link and a Review of the Literature by Rouhin Sen, Kathleen Borghoff, Kirk W. Foster, Stanley J. Radio, Alan Erickson, Michelene Hearth-Holmes

“…We will examine the case presentations of three female Caucasian patients: a 22-year-old with lupus nephritis class V, a 72-year-old with long-standing systemic lupus erythematosus, and a 74-year-old with undifferentiated connective tissue disease. …”
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Complicaciones maternas, fetales y neonatales en Embarazadas con enfermedades Autoinmunitarias sistémicas, y su seguimiento con flujometría Doppler. by Yoel Cardet Niebla, Juan Carlos Ojeda Blanco, Yosdaily Guerra Aroche, Flabia Toledo Mederos

“…Se empleó las pruebas estadísticas de homogeneidad de chi cuadrado (X 2); se fijó un nivel de confiabilidad del 95 %, para el cual, si la significación estadística del estadígrafo X 2 fue menor que 0,05, entonces se rechazó la hipótesis nula y considero hubo diferencias significativas Resultados: El Lupus eritematoso sistémico fue la enfermedad autoinmune más frecuente con un 74%, dentro de las complicaciones maternas fetales, la restricción fetal con 34 casos, la preeclampsia con 43 casos y el parto pretérmino con 27 casos y las mismas se presentaron en más del 60% de pacientes con lupus. …”
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Lack of Antilipoprotein Lipase Antibodies in Takayasu's Arteritis by Jozélio Freire de Carvalho, Rosa Maria Rodrigues Pereira, Vilma Santos Trindade Viana, Eloísa Bonfá, Yehuda Shoenfeld

“…Antilipoprotein lipase (anti-LPL) antibodies were described in rheumatic diseases. In systemic lupus erythematosus they were highly associated with inflammatory markers and dyslipidemia, and may ultimately contribute to vascular damage. …”
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Rituximab (monoclonal anti-CD20 antibody) induced posterior reversible encephalopathy syndrome (PRES): A case report and literature review by Praveen K. Sharma, MD, Sanjaykanth Balachandar, MBBS, Michael Antony Vikram, MBBS, Pujitha Duvooru Sukumar, MD

“…Here, we present a 23-year-old female patient with systemic lupus erythematosus (SLE) and lupus nephritis who developed PRES following Rituximab (a monoclonal anti-CD-20 antibody) administration. …”
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Fn14 Deficiency Ameliorates Anti-dsDNA IgG-Induced Glomerular Damage in SCID Mice by Jiawen Wu, Xiaoyun Min, Li Wang, Jie Yang, Ping Wang, Xingyin Liu, Yumin Xia

“…Many studies have demonstrated that anti-dsDNA IgG is closely associated with lupus nephritis. Recently, it was found that activation of the fibroblast growth factor-inducible 14 (Fn14) signaling pathway damages glomerular filtration barrier in MRL/lpr lupus-prone mice. …”
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A Curious Case of Rowell Syndrome by Seetharaman Venugopalan Iyer, Delnaz Palsetia, Alka A. Subramanyam

“…Rowell syndrome is a rare disease consisting of erythema multiforme-like lesions coexisting with lupus erythematosus along with characteristic immunological findings. …”
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Omalizumab for Urticarial Vasculitis: Case Report and Review of the Literature by Misbah Nasheela Ghazanfar, Simon Francis Thomsen

“…It is often idiopathic but is sometimes associated with collagen-vascular disease, particularly systemic lupus erythematosus. Treatment options include oral antihistamines, oral corticosteroids, dapsone, colchicine or hydroxychloroquine. …”
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HELLP Syndrome Complicated with Postpartum Subcapsular Ruptured Liver Hematoma and Purtscher-Like Retinopathy by Daniela Cernea, Alice Dragoescu, Marius Novac

“…Purtscher's retinopathy is usually associated with trauma, acute pancreatitis, vasculitis, lupus, and bone fractures. It was rarely described postpartum in patients with preeclampsia as well as associated with HELLP syndrome. …”
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Porphyria Cutanea Tarda with Constrictive Pericarditis: A Rare Association by Kaur Jasleen, Nidhi Sharma, Jyotika Kalsy, Mughda Sharma

“…PCT is frequently associated with diabetes mellitus, lupus erythematosus and hepetitis C virus infection. …”
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