Extraction efficiency and bioactive evaluation of Tamarix nilotica and Arthrocnemum macrostachyum extracts for anti-cancer potential. by Maryam Al Kaabi, Nancy A ElNaker, Nila Jan, Michael A Ochsenkühn, Shady A Amin, Lina F Yousef, Ahmed F Yousef

“…Results suggest that: 1) MAE is more efficient than maceration in recovering metabolites from plant biomass based on measurements of total phenolic content, radical scavenging activity, and bioactivity of extracts based on in vitro cytotoxicity. 2) Only T. nilotica extracts were found to be bioactive based on cytotoxicity measurements. 3) Cancer cell lines displayed differential sensitivity to T. nilotica crude extracts, with breast cancer cells being the most sensitive and lung cancer cells being the least sensitive. 4) Solid-phase fractionation of T. nilotica crude extract using different percentages of methanol resulted in several fractions that were 100-fold more cytotoxic compared to the crude unfractionated extract. …”
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Somatic Mutaome Profile in Human Cancer Tissues by Nayoung Kim, Yourae Hong, Doyoung Kwon, Sukjoon Yoon

“…The majority of tissue samples harbored 20-80 different mutant genes, on average. Lung cancer samples showed a greater number of mutations in diverse genes than other cancer subtypes. …”
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Paraneoplastic Limbic Encephalitis Resembling Acute Herpetic Encephalitis by Ioannis Markakis, Athanasios Papathanasiou, Ermioni Papageorgiou, Kostantinos Siarkos, Georgios Gkekas

“…Chest CT showed a right paratracheal lymph node mass, while a biopsy revealed neuroendocrine lung cancer. Auto antibodies to Hu were also detected. …”
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A pan-cancer analysis of MARCH8: molecular characteristics, clinical relevance, and immuno-oncology features by Zihan Quan, Songqing Fan, Hongmei Zheng, Yue Ning, Yang Yang

“…The expression of MARCH8 protein was detected via immunohistochemistry in non-small cell lung cancer (NSCLC) and non-cancerous lung tissues. …”
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Therapeutic Targeting of MOAP-1 in Cancer: A Systematic Review of Current Approaches and Future Directions by Xinwei Koong, Keyun Look, Amar Daud Iskandar Abdullah, Kuan Onn Tan, Vasudevan Mani, Hooi-Leng Ser, Khang Wen Goh, Ali Saleh Alkhoshaiban, Long Chiau Ming

“…Its potential as a therapeutic target in bladder, breast, and non-small cell lung cancer (NSCLC) offers intriguing new therapeutic approaches. …”
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Impact of stain variation and color normalization for prognostic predictions in pathology by Siyu Lin, Haowen Zhou, Mark Watson, Ramaswamy Govindan, Richard J. Cote, Changhuei Yang

“…This study used sample data from a previously reported DNN that was able to identify patients with early-stage non-small cell lung cancer (NSCLC) whose tumors did and did not metastasize, with high accuracy, based on training and then testing of digital images from H&E stained primary tumor tissue sections processed at the same time. …”
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Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases by Jialian Lv, Xinyue Song, Zixin Luo, Duoqin Huang, Li Xiao, Kang Zou

“…Luteolin has therapeutic effects on chronic obstructive pulmonary disease (COPD), acute lung injury/acute respiratory distress syndrome (ALI/ARDS), pulmonary fibrosis, allergic asthma, and lung cancer. Luteolin, a naturally occurring polyphenol, is poorly water-soluble. …”
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Research Progress of Fuzheng Jiedu Huayu Method in Reducing Toxicity and Enhancing Efficacy of Immunotherapy by Yufan CHEN, Sicong LI, Yiyuan CUI, Li FENG

“…Immune checkpoint inhibitors, which block programmed death receptor 1 or programmed death ligand 1, have been included in the first-line clinical treatment for advanced solid tumors, such as non-small cell lung cancer and malignant melanoma. However, primary or secondary drug resistance in tumors severely limits the survival benefits for patients. …”
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An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene by Fayeza Sadia Laskar, Md. Nazmul Islam Bappy, Md. Sowrov Hossain, Zenifer Alam, Dilruba Afrin, Sudeb Saha, Kazi Md. Ali Zinnah

“…These mutations can change the structure and function of MET leading to different diseases such as lung cancer, neck cancer, colorectal cancer, and many other complex syndromes. …”
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A novel hybrid CLARA and fuzzy time series Markov chain model for predicting air pollution in Jakarta by Nurtiti Sunusi, Ankaz As Sikib, Sumanta Pasari

“…Poor air quality increases risks of respiratory inflammation, tuberculosis, asthma, chronic obstructive pulmonary disease (COPD), pneumoconiosis, and lung cancer.In this context, developing reliable air pollution forecasting models is imperative for guiding effective mitigation strategies and policy interventions. …”
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Chemical tools to define and manipulate interferon-inducible Ubl protease USP18 by Griffin J. Davis, Anthony O. Omole, Yejin Jung, Wioletta Rut, Ronald Holewinski, Kiall F. Suazo, Hong-Rae Kim, Mo Yang, Thorkell Andresson, Marcin Drag, Euna Yoo

“…We further demonstrate that USP18 ABPs can be utilized to profile differential activities of USP18 in lung cancer cell lines, providing a strategy that will help define the activity-related landscape of USP18 in different disease states and unravel important (de)ISGylation-dependent biological processes.…”
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The Relationship of Sirtuin 1 and Sirtuin 2 Expression with Clinicopathological Parameters in Non Small-Cell Lung Carcinomas by Fatma Cakmak Kazanci, Nagehan Barisik Ozdemir, Sibel Sensu, Cem Cahit Barisik

“…We aimed to investigate the association between Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) immunohistochemical (IHC) protein expression in tumors and clinicopathological parameters and survival profiles in non-small cell lung cancer (NSCLC) patients. Methods: This retrospective observational study reviewed lung resections (lobectomy, segmentectomy, wedge resection, and pneumonectomy) of 186 patients diagnosed with NSCLC (adenocarcinoma, squamous cell carcinoma, and adenosquamous carcinoma). …”
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Risk of second primary malignancies among survivors of cutaneous melanoma: A nationwide population-based study in the Republic of Korea by Joon Min Jung, Do Hyung Kim, Ye-Jee Kim, Ik Jun Moon, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Chong Hyun Won

“…Additionally, specific SPMs were more common among melanoma survivors, including nonmelanoma skin cancer, oral cavity and pharyngeal cancer, renal cancer, female breast cancer, lung cancer, pancreatic cancer, and liver cancer. Independent risk factors for overall SPM development included a Charlson Comorbidity Index ≥ 1 (adjusted hazard ratio [aHR], 1.41; 95% CI, 1.07–1.87), and a body mass index ≥ 25 kg/m2 (aHR, 1.47; 95% CI, 1.04–2.08). …”
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Characterizing Radon Among Public Buildings and Small/Medium-Sized Businesses in a Canadian Province by Lily X. Yang, Tracy L. Kirkham, Laura Boksman, Anne-Marie Nicol, Paul A. Demers

“…Radon is a naturally occurring radioactive gas that causes lung cancer. It has been measured extensively in homes and mines but research in other workplaces has been limited. …”
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Minimally Invasive Bilateral Lung Resections and CABG through 5 Ports by N. Asemota, M. J. Rouhani, L. Harling, H. Raubenheimer, A. C. De Souza, E. Lim

“…An 81-year-old woman was diagnosed with T1aN0M0 left upper lobe small-cell lung cancer and underwent single-port left video-assisted thoracoscopic surgery (VATS) upper lobectomy in 2016. …”
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TEEG Induced A549 Cell Autophagy by Regulating the PI3K/AKT/mTOR Signaling Pathway by Lu Shi, Yijun Tu, Yu Xia, Siqi Ye, Chaozhi Ma, Yanwen Liu, Pengtao You

“…In the present study, we aimed to elucidate the anticancer effect and possible molecular mechanism underlying the action of TEEG against the human non-small cell lung cancer (NSCLC) cell line A549 in vitro. A549 cells were incubated with different concentrations of TEEG. …”
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Mechanisms of (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (huang qi) and (Oliv.) Diels (dang gui) in Ameliorating Hypoxia and Angiogenesis to Delay Pulmonary Nodule Malignant Tra... by Ying Guo PhD, Peng Yang MS, Zihong Wu PhD, Sanyin Zhang PhD, Fengming You PhD

“…Screening for pulmonary nodules (PN) using low-dose CT has proven effective in reducing lung cancer (LC) mortality. However, current treatments relying on follow-up and surgical excision fail to fully address clinical needs. …”
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Actin-Binding Proteins as Potential Biomarkers for Chronic Inflammation-Induced Cancer Diagnosis and Therapy by Yu-Gui Zhang, Jiang-Tao Niu, Hong-Wei Wu, Xin-Lei Si, Shu-Juan Zhang, Dong-Hui Li, Tian-Tian Bian, Yue-Feng Li, Xing-Ke Yan

“…This is the case for breast cancer, gastric cancer, lung cancer, prostate cancer, liver cancer, esophageal cancer, pancreatic cancer, melanoma, and colorectal cancer. …”
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Synthesis, Characterization, and Cytotoxicity Research of Sulfur-Containing Metal Complexes by Yanting Yang, Danqin Li, Mei Luo

“…In terms of application, the biological activity of complexes (I)–(III) in human cancer cell lines (lung cancer A549, liver cancer SMMC-7721, breast cancer MDA-MB-231, and colon cancer SW480) was tested using the MTS method. …”
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Risk of recurrence and bleeding in patients with cancer‐associated venous thromboembolism treated with rivaroxaban: A nationwide cohort study by Mette Søgaard, Peter Brønnum Nielsen, Flemming Skjøth, Jette Nordstrøm Kjældgaard, Torben Bjerregaard Larsen

“…Major bleeding occurred in 1.9% (5.3 events per 100 person‐years), in particular, in genitourinary cancer (4.5%) and lung cancer (4.2%). Eighty deaths (17.8%) occurred during follow up. …”
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