A Rare Case of Penile Metastases as a Harbinger of Primary Pulmonary Adenosquamous Carcinoma by Partha Hota, Tejas N. Patel, Xiaofeng Zhao, Carrie Schneider, Omar Agosto

“…Although lung cancer has a high propensity for distant metastatic disease, penile metastases from primary lung neoplasms are considered particularly rare. …”
Get full text

Mucoepidermoid Carcinoma of the Lung: A Case Report and Literature Review by S. Alsidawi, J. C. Morris, K. A. Wikenheiser-Brokamp, S. L. Starnes, N. A. Karim

“…Mucoepidermoid carcinoma (MEC) of the lung is a rare form of lung cancer that is classified into low grade and high grade based on histological features. …”
Get full text

No Apparent Workup for most new Indeterminate Pulmonary Nodules in US Commercially-Insured Patients by Bruce S. Pyenson, Carol M. Bazell, Michael J. Bellanich, Melissa A. Caplen, Javier J. Zulueta

“…**Background:** A recent study estimated that more than 1.5 million Americans have an indeterminate pulmonary nodule (IPN) identified on a chest computed tomography (CT) scan each year outside of lung cancer screening programs. However, the cost and pattern of subsequent IPN workup have not been described for real-world settings. …”
Get full text

Adaptive genetic algorithm based deep feature selector for cancer detection in lung histopathological images by Avigyan Roy, Priyam Saha, Nandita Gautam, Friedhelm Schwenker, Ram Sarkar

“…The source code for this work can be found https://github.com/priyam-03/GA-Feature-Selector-Lung-Cancer .…”
Get full text

In Vitro Model for Studying Malignancy Associated Changes by Xiao Rong Sun, Yonghong Zheng, Calum MacAulay, Stephen Lam, Alexei Doudkine, Branko Palcic

“…An in vitro cell culture model system was designed to study interactions between non‐small cell lung cancer (NSCLC) and the normal bronchial epithelium of the human respiratory tract in vivo to see if the MAC‐like phenomenon can be detected in such a system. …”
Get full text

Increased PPARD Expression May Play a Protective Role in Human Lung Adenocarcinoma and Squamous Cell Carcinoma by Yong Zhu, Yedong Mi, Zhonghua Qin, Xuewei Jiang, Yibo Shan, Kamil Kural, Guiping Yu

“…Peroxisome proliferator-activated receptor-δ, encoded by gene PPARD, is overexpressed in a majority of human lung cancer subtypes, but its role in the tumor progression remains poorly understood. …”
Get full text

The discovery and characterization of K‐563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp by Ran Hori, Kozo Yamaguchi, Hidetaka Sato, Miwa Watanabe, Kyoko Tsutsumi, Susumu Iwamoto, Masayuki Abe, Hideyuki Onodera, Satoshi Nakamura, Ryuichiro Nakai

“…K‐563 also exerted synergistic combinational effects with lung cancer chemotherapeutic agents. An in vivo study in mice xenotransplanted with A549 cells to further explore the therapeutic potential of K‐563 revealed that it also inhibited Keap1/Nrf2 pathway in lung cancer tumors. …”
Get full text

Hospice Care by Suzanna Smith

“…“Recently a friend’s mother, Alice, was diagnosed with lung cancer, and even though she received all the possible treatments, the cancer was incurable. …”
Get full text

Hospice Care by Suzanna Smith

“…“Recently a friend’s mother, Alice, was diagnosed with lung cancer, and even though she received all the possible treatments, the cancer was incurable. …”
Get full text

Squeeze-and-Excitation Vision Transformer for Lung Nodule Classification by Xiaozhong Xue, Yanhe Ma, Weiwei Du, Yahui Peng

“…Lung cancer is one of the deadliest cancers. Early diagnosis of lung cancer can increase the 5-year survival rate to 70%, and the lung nodule classification is the basis for early diagnosis. …”
Get full text

Are Onconeural Antibodies a Clinical Phenomenology in Paraneoplastic Limbic Encephalitis? by Hongliang Zhang, Chunkui Zhou, Limin Wu, Fengming Ni, Jie Zhu, Tao Jin

“…Most of these clinical syndromes in adults are associated with lung cancer, especially small cell lung cancer (SCLC), lymphoma, and gynecological tumors. …”
Get full text

A Novel In Situ Dendritic Cell Vaccine Triggered by Rose Bengal Enhances Adaptive Antitumour Immunity by Lanlin Zhang, Jiangyuan Du, Qian Song, Chufan Zhang, Xianghua Wu

“…This study reveals that the RB-iDC vaccine can synergistically destroy the primary tumour, inhibit distant metastasis, and prevent tumour relapse in a lung cancer mouse model, which provides important preclinical data for the development of a novel combinatorial immunotherapy.…”
Get full text

Genetic analysis of ocular tumour-associated genes using large genomic datasets: insights into selection constraints and variant representation in the population by Jose S Pulido, Mandeep S Sagoo, Omar A Mahroo, Alexander Tanner

“…Ocular tumour-associated genes exhibited higher scores for haploinsufficiency and triplosensitivity compared with breast and lung cancer-associated genes. Pathway analysis revealed significant enrichment in cellular proliferation, differentiation and division. …”
Get full text

Characterization, Distribution, and Risk Assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in the Workplaces of an Electric Arc Furnace (EAF) Steelmaking Factory by Ying-Fang Wang, Riza P. Gumaling, Mei-Ru Chen, Yu-Chieh Kuo, Lin-Chi Wang

“…Abstract This study measured workplace polycyclic aromatic hydrocarbons (PAHs) in an electric arc furnace (EAF) factory during regular and maintenance periods and estimated workers’ lung cancer risk from 40 years of exposure using Monte Carlo Simulation. …”
Get full text

Risk factors for emergency presentation with lung and colorectal cancers: a systematic review by Una MacLeod, Elizabeth D Mitchell, Benjamin Pickwell-Smith

“…Higher deprivation increased the likelihood of lung cancer EP, but evidence for colorectal was less conclusive. …”
Get full text

Effects of Activating Mutations on EGFR Cellular Protein Turnover and Amino Acid Recycling Determined Using SILAC Mass Spectrometry by Michael J. Greig, Sherry Niessen, Scott L. Weinrich, Jun Li Feng, Manli Shi, Ted O. Johnson

“…Utilizing SILAC MS, we measured the cellular turnover rates of an important non-small cell lung cancer target, epidermal growth factor receptor (EGFR). …”
Get full text

Dramatic response of advanced pulmonary sarcomatoid carcinoma to tislelizumab combined with anlotinib: a case report by Ranran Li, Xiliang Di, Yuan Li, Hao Li, Chonghua Liu

“…Pulmonary sarcomatoid carcinoma (PSC) is a scarce pathologic type of lung cancer of non-small cell lung cancer (NSCLC) that exhibits resistance to conventional chemotherapy and radiotherapy, resulting in a poor prognosis. …”
Get full text

Pre-therapeutic efficacy of the CDK inhibitor dinaciclib in medulloblastoma cells by Marta Buzzetti, Sonia Morlando, Dimitrios Solomos, Ammara Mehmood, Alexander W. I. Cox, Mattia Chiesa, Yuri D’Alessandra, Michela Garofalo, Caroline H. Topham, Gianpiero Di Leva

Get full text

BMI1, ALDH1A1, and CD133 Transcripts Connect Epithelial-Mesenchymal Transition to Cancer Stem Cells in Lung Carcinoma by Ana Koren, Matija Rijavec, Izidor Kern, Eva Sodja, Peter Korosec, Tanja Cufer

“…Epithelial-mesenchymal transition (EMT) is the underlying mechanism of tumor invasion and metastasis. Evidences from lung cancer cellular models show EMT can trigger conversion to a cancer stem cell (CSC) phenotype. …”
Get full text

Lipid-lowering drug targets and lung related diseases: a Mendelian randomization study by Haifeng Yu, Xiaofei Zhang, Bian Wen, Shuo Hu, Bin Ni

“…RESULTS Our study did not find any significant association between genetically proxied APOB, CETP, HMGCR, NPCIL, PCSK9, and LDLR inhibition (equivalent to a one standard deviation reduction in LDL-C) with the risk of Small Cell Lung Cancer, Non-Small Cell Lung Cancer, idiopathic pulmonary fibrosis, and Pneumonia (P > 0.05). …”
Get full text