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Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial
Published 2024-02-01“…We report updated efficacy and safety in all randomized patients with a minimum 4-year follow-up and an exploratory treatment-switching adjustment analysis in all treated patients who received chemotherapy and subsequent immunotherapy.Methods Adults with stage IV/recurrent non-small cell lung cancer (NSCLC), no sensitizing EGFR/ALK alterations, and ECOG performance status ≤1 were randomized 1:1 to nivolumab 360 mg every 3 weeks plus ipilimumab 1 mg/kg every 6 weeks with chemotherapy (two cycles) or chemotherapy (four cycles, with optional maintenance pemetrexed for the nonsquamous population). …”
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One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis
Published 2025-01-01Subjects: “…Multiple primary lung cancers…”
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Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developing a prognostic multivariate model
Published 2022-05-01“…However, the clinical significance of free amino acids (plasma-free amino acids (PFAAs)) and tryptophan-related metabolites in plasma has not been fully understood in patients with non-small cell lung cancer (NSCLC) who receive immune checkpoint inhibitors.Methods We conducted a single cohort observational study. …”
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Gliadin encapsulated PCOs nanoformulation: An effective therapeutic option for metastatic breast cancer
Published 2025-06-01Subjects: Get full text
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BRAF V600E-mutated lung adenocarcinoma with thyroid metastasis as the initial manifestation: a case report
Published 2025-02-01Subjects: “…non-small cell lung cancer (NSCLC)…”
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Pembrolizumab and Pemetrexed for Older Patients With Nonsquamous NSCLC and Programmed Cell Death-Ligand 1 Tumor Proportion Scores of Less Than 50%
Published 2025-03-01Subjects: “…Nonsquamous non-small cell lung cancer…”
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Glutamine deprivation confers immunotherapy resistance by inhibiting IFN-γ signaling in cancer cells
Published 2025-03-01Subjects: Get full text
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Cannabidiol Vaping–Associated Multifocal NSCLC in a 24-Year-Old Female: A Case Report
Published 2025-03-01Subjects: Get full text
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Colorimetric aptasensor coupled with a deep-learning-powered smartphone app for programmed death ligand-1 expressing extracellular vesicles
Published 2025-01-01Subjects: Get full text
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Immune Checkpoint Inhibitors +/− Chemotherapy for Patients With NSCLC and Brain Metastases: A Systematic Review and Network Meta‐Analysis
Published 2025-01-01Subjects: Get full text
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TClC effectively suppresses the growth and metastasis of NSCLC via polypharmacology
Published 2025-03-01Subjects: “…Non-small cell lung cancer…”
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Low-exhaustion peripheral circulating γδ T cells serve as a biomarker for predicting the clinical benefit rate of non-small cell lung cancer (NSCLC) patients to chemotherapy or targeted therapy: a single-center retrospective study
Published 2025-01-01“…Methods Patients with EGFR wild-type (EGFR-WT) or mutant (EGFR-Mut) non-small cell lung cancer (NSCLC), diagnosed between January 2020 and January 2024, were included in this study. …”
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Lithium-Acetate-Mediated Biginelli One-Pot Multicomponent Synthesis under Solvent-Free Conditions and Cytotoxic Activity against the Human Lung Cancer Cell Line A549 and Breast Cancer Cell Line MCF7
Published 2012-01-01“…The prepared compounds are evaluated for anticancer activity against two human cancer cell lines (lung cancer cell line A549 and breast cancer cell line MCF7).…”
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