An overview of breast cancer: Classification and related signaling pathways by Pit Foong Chan, Roslida Abd Hamid

“… The burden of cancer continues to grow in developed and developing countries, with about 70% of all cancer mortality in low- and middle-income countries. Among different cancer types, breast cancer is recognized as one of the five most common causes of death in cancer in women worldwide, right after lung cancer. …”
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Female genital tuberculosis presenting as a protruding anterior vaginal wall mass: a case report by Mequanint Melesse Bicha, Tewodros Zenabu Kebede, Ayalew Lingerih Arefeaynie, Eden Woldegerima Meressa

“…Although pulmonary tuberculosis is a common infectious disease, especially in low-and middle-income countries, female genital tract tuberculosis (TB) is rarely reported. …”
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Predicting the Effectiveness of Resilient Safety in the Building Construction Sector of Rwanda Using the ANN Model by Esperance Umuhoza, Sung-Hoon An

“…This study contributes to the awareness of key factors that may affect the effectiveness of resilient safety, and it helps to forecast the effectiveness of resilient safety not only in Rwanda, but also in other low- and middle-income countries with different conditions by stressing the importance of reducing safety-related risks in building construction projects.…”
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Role of plasmids in antibiotic resistance in clinical infections and implications for epidemiological surveillance: a review by Ayodele Oluwaseun Ajayi, Olajide Joseph Akinjogunla, Adebowale Toba Odeyemi, Akinyomade Oladipo Owolabi

“…Unfortunately, access to such technologies is limited in low- and middle-income countries (LMICs). The major aim of this review is to examine the specific contributions of plasmids to the upsurge of AR in clinical settings and elucidate the various replicon types that have been attributed to specific antibiotic-resistant infections in healthcare settings. …”
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What interventions are required to reduce road traffic injuries in Africa? A scoping review of the literature. by Emmanuel Bonnet, Lucie Lechat, Valéry Ridde

“…No progress has been reported in Low and Middle Income Countries (LMICs) and the number of deaths remains very high. …”
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Artificial intelligence (AI) or augmented intelligence? How big data and AI are transforming healthcare: Challenges and opportunities by K Moodley

“…Global guidelines are emerging to ensure governance in AI, but many low- and middle-income countries have yet to develop context- specific frameworks. …”
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Exploring shifts in values among urban Senegalese: The impact of global crises on social and cultural norms. by Yachiyo Tobita, Mandiaye Diagne, Joseph Bassama, Moussa Ndong, Mor Gueye, Kiyokazu Ujiie

“…In addition, the Russia-Ukraine war that began in 2022 resulted in rising food prices globally, severely affecting low- and middle-income countries. This study aimed to examine the impact of these unprecedented crises on individual values, focusing on Senegal's urban population. …”
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Advancing Gender Equity in Health: The Role of Medical Women’s International Association by Wajiha Rizwan, Eleanor Nwadinobi

“…MWIA’s 2022-2025 theme, "One Humanity: Health Solutions through Our Partnerships," stresses the importance of collaboration to address gender inequities, particularly in low- and middle-income countries. Notable initiatives include the Equity 2030 Alliance with UNFPA, focusing on women-centric research, and the ‘Every Woman Treaty’ advocating for global standards to end violence against women. …”
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A Comprehensive Review of the Diagnostics for Pediatric Tuberculosis Based on Assay Time, Ease of Operation, and Performance by Soumya Basu, Subhra Chakraborty

“…Pediatric tuberculosis (TB) is still challenged by several diagnostic bottlenecks, imposing a high TB burden in low- and middle-income countries (LMICs). Diagnostic turnaround time (TAT) and ease of operation to suit resource-limited settings are critical aspects that determine early treatment and influence morbidity and mortality. …”
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Estimating the Impact and Cost of the WHO 2010 Recommendations for Antiretroviral Therapy by John Stover, Lori Bollinger, Carlos Avila

“…Results indicate that switching the eligibility criterion from CD4 count <200 to <350 increases the need for ART in low- and middle-income countries (country-level) by 50% (range 34% to 70%). …”
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Barriers to and impacts of hepatitis C treatment among people who inject drugs in Kenya: A qualitative study. by Hannah N Manley, Lindsey R Riback, Mercy Nyakowa, Matthew J Akiyama, Peter Cherutich, John Lizcano, Ann Kurth, Abbe Muller

“…Despite availability of safe and effective treatment, HCV treatment access and uptake among PWID in low- and middle-income countries (LMICs) has been limited. Understanding the lived experiences of PWID in these settings who have undergone treatment provides the opportunity to gain insight into how to implement treatment programs that meet the needs of this population. …”
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Community-based model for management and follow-up by non-physician healthcare workers to improve awareness, treatment, and control of hypertension: The COTRACO study protocolDetai... by A.J. Lora Mantilla, L.A. Parra Gomez, P.A. Camacho-López, J. Otero-Wandurraga, B. Novella, A. González-Medina, O. Valdez-Tiburcio, F. Lanas, M.C. Rocha-Lezama, J. Alonzo-Arias, C. Rivilla-Piñango, C. Cáceres-Ramírez, S.J. Villabona-Flórez, Y.M. Giraldo-Castrillón, P. López-Jaramillo

“…On this basis, the COTRACO study aims to address the barriers to hypertension treatment in low- and middle-income countries by implementing a similar standardized treatment approach delivered by non-specialist health workers. …”
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Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect. by Tshokey Tshokey, Ablert I Ko, Bart J Currie, Claudia Munoz-Zanzi, Cyrille Goarant, Daniel H Paris, David A B Dance, Direk Limmathurotsakul, Emma Birnie, Eric Bertherat, Gyanendra Gongal, Jackie Benschop, Jelmer Savelkoel, John Stenos, Kartika Saraswati, Matthew T Robinson, Nicholas P J Day, Stephen R Graves, Steven R Belmain, Stuart D Blacksell, Willem J Wiersinga

“…Three potentially life-threatening endemic bacterial diseases (leptospirosis, melioidosis, and rickettsioses) are a huge public health concern especially in low- and middle-income countries. Despite their continued threat, these diseases do not receive proportionate attention from global health organizations and are not even included on the WHO list of neglected tropical diseases (NTDs). …”
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Potential Use and Limitation of Artificial Intelligence to Screen Diabetes Mellitus in Clinical Practice: A Literature Review by Aqsha Nur, Defin Yumnanisha, Sydney Tjandra, Adang Bachtiar, Dante Saksono Harbuwono

“…The burden of undiagnosed diabetes mellitus (DM) is substantial, with approximately 240 million individuals globally unaware of their condition, disproportionately affecting low- and middle-income countries (LMICs), including Indonesia. …”
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Financial inclusion for people with disability: a scoping review by Louise Puli, Natasha Layton, Diane Bell, Abu Zafar Shahriar

“…Evidence demonstrates that financial exclusion is exacerbated for people with disability and those in low- to middle-income countries (LMIC). Barriers to financial access include limited demand for services, banking inadequacies in catering to people with disability, and insufficiently accessible information technologies (ICT) and infrastructure. …”
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Exploring HIV-Related Stigma and Discrimination at the Workplace in Southwestern Uganda: Challenges and Solutions by Benedict Twinomugisha, Fungisai Gwanzura Ottemöller, Marguerite Daniel

“…Despite several health promotion interventions being carried out, HIV/AIDS remains a major cause of deaths in low and middle income countries. At the workplace, the pandemic has brought about reduction in productivity, increased staff turnover, increased production costs, high levels of stigma, etc. …”
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A manifesto for a globally diverse, equitable, and inclusive open science by Sakshi Ghai, Rémi Thériault, Patrick Forscher, Yuichi Shoda, Moin Syed, Arathy Puthillam, Hu Chuan Peng, Dana Basnight-Brown, Asifa Majid, Flavio Azevedo, Leher Singh

“…Additionally, macro-level geopolitical factors must be considered to move towards a robust behavioural science that is truly inclusive, representing the voices and experiences of the majority world (i.e., low-and-middle-income countries).…”
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A systematised review and evidence synthesis on the broader societal impact of vaccines against Salmonella by Ezgi Dilek Demirtas, Rosanna Barnard, Jungseok Lee, Mark Jit

“…We reviewed literature on these broader impacts in low- and middle-income countries to inform a conceptual framework. …”
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Investigating the Feasibility and Impact of Perinatal Depression Screening and Treatment in Rural Nsambe, Malawi by Waste Kayira, Mark Chalamanda, Kingsley Kanzoole, Kondwani Mpinga, Moses Banda Aron, Ksakred Kelly, Sarah Singer, Enoch Ndarama, Stephanie Smith, Giuseppe Raviola, Basimenye Nhlema, Emilia Connolly, Todd Ruderman

“…Perinatal depression contributes significantly to morbidity and mortality of women and children in low- and middle-income countries. However, due to low resources and little evidence on the impact of screening and treatment, few interventions are offered. …”
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Antivirals for the treatment of mild and moderate COVID-19 in South Africa by R Perumal, V Naidoo, S Govender, T N Gengiah

“…Given the low vaccine uptake in SA and other low‐ and middle‐income countries in sub‐Saharan Africa, the high prevalence of comorbidities and limited healthcare system capacity, evidence‐based interventions that reduce the risk of severe disease and death should be considered for implementation. …”
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