<i>KRAS</i>, <i>NRAS</i>, and <i>BRAF</i> Hot-Spot Mutations in Relation to Sidedness of Primary Colorectal Cancer: A Retrospective Cohort Study by Omer Abdelgadir, Yong-Fang Kuo, Anthony O. Okorodudu, M. Firoze Khan, Yu-Wei Cheng, Jianli Dong

“…<b>Methods:</b> We performed a retrospective cohort analysis of 722 patients diagnosed with primary CRC and tested for <i>KRAS</i>, <i>NRAS</i>, and <i>BRAF</i> hot-spot mutations at the University of Texas Medical Branch (UTMB) from January 2016 through July 2023. Multivariable logistic regressions analyses were conducted. <b>Results:</b><i>KRAS</i>, <i>NRAS</i>, and <i>BRAF</i> hot-spot mutations rates were 37.8%, 4.6%, and 6.1%, respectively. …”
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Vitamin D binding protein genetic isoforms, serum vitamin D, and cancer risk in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. by Stephanie J Weinstein, Dominick Parisi, Alison M Mondul, Tracy M Layne, Jiaqi Huang, Rachael Z Stolzenberg-Solomon, Regina G Ziegler, Mark P Purdue, Wen-Yi Huang, Christian C Abnet, Neal D Freedman, Kai Yu, Demetrius Albanes

“…Multivariable-adjusted logistic regression models estimated odds ratios (ORs) and 95% confidence intervals (CIs) of cancer risk according to 25(OH)D quantiles, stratified by Gc isoform. …”
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Aldehyde Dehydrogenase 2 rs671 Polymorphism is Associated with Susceptibility of Coronary Atherosclerosis in Patients with Hypertension by Hou H, Huang S, Huang W, Huang L, Zhang Z, Liang L

“…The frequency of the ALDH2 rs671 G/A genotype, and the levels of TC, LDL-C, PIV, SII, and SIRI in patients with coronary atherosclerosis were higher than those in controls. Logistic analysis showed that body mass index (BMI) ≥ 24.0 kg/m2 (odds ratio (OR): 1.670, 95% confidence interval (CI): 1.185– 2.352, p=0.003), history of smoking (OR: 2.024, 95% CI: 1.263– 3.243, p=0.003), ALDH2 rs671 G/A genotype (OR: 1.821, 95% CI: 1.280– 2.589, p=0.001), high TC (OR: 1.592, 95% CI: 1.021– 2.485, p=0.040), high SII (OR: 2.290, 95% CI: 1.386– 3.784, p=0.001), and high SIRI (OR: 1.727, 95% CI: 1.126– 2.650, p=0.012) were associated with coronary atherosclerosis in patients with hypertension.Conclusion: Overweight (BMI ≥ 24.0 kg/m2), history of smoking, ALDH2 rs671 G/A genotype, high TC, SII, and SIRI levels were associated risk factors for coronary atherosclerosis in patients with hypertension.Keywords: coronary atherosclerosis, hypertension, ALDH2, systemic immune inflammation index, system inflammation response index…”
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Inpatient autopsy rate and associated factors in a Chinese megacity: a population-based retrospective cohort study by Yu Wang, Jiming Zhu, Zihan Wang, Dachun Zhao, Hange Li, Yanrong He, Xidong Guo, Hanbo Zhang, Huatang Zeng

“…Among them, a total of 34 577 cases with complete data, classified hospital and Chinese nationality, were included for further multivariable rare events logistic regression and Poisson pseudo maximum likelihood regression.Outcome measures Whether the inpatient death was autopsied or not.Results The autopsy procedure was performed in 0.9% (319/35 272) of hospital deaths. …”
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Explore the factors related to the death of offspring under age five and appraise the hazard of child mortality using machine learning techniques in Bangladesh by Ashikur Rahman, Md. Habibur Rahman

“…Six ML-based algorithms were implemented for predicting child mortality, such as Naïve Bayes, Classification and Regression Trees, Random Forest, C5.0 Classification, Gradient Boosting Machine, and Logistic Regression. Model evaluation metrics like accuracy, specificity, sensitivity, negative predictive value, $$F_1$$ F 1 score, positive predictive value, k-fold cross-validation, and area under the curve (AUC) techniques were used to evaluate the performance of the models. …”
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Psychological Status and Related Factors in Medical Isolated Persons during Outbreak of COVID-19 by Qin WANG, LI Li, Xia ZHOU, Zhimei LIU, Bingshan GUO, Renqi DONG

“…The General Anxiety Disorder Scale-7 (GAD-7) was used to evaluate anxiety state, and the Patient Health Questionnaire-9 (PHQ-9) depression screening scale was used to evaluate depression state.Results:1) Among the 124 medical isolation residents,106 (85.48%) had anxiety-related mood changes (GAD-7&gt;4) and 96 (77.42%) had depression-related mood changes (PHQ-9&gt;4).2) Univariate analysis showed that the educational level, the scores of GAD-7 were statistically significant with different educational levels, the amount of negative information received about the COVID-19 and occupational classification (<italic>P</italic>=0.03, <italic>P</italic>=0.002, <italic>P</italic>=0.04), while the scores of PHQ-9 were statistically significant with different marital status, educational levels, occupational classification (<italic>P</italic>=0.04, <italic>P</italic>=0.002, <italic>P</italic>=0.02).3) Multiple <italic>Logistic</italic> regression analysis showed that the amount of negative information received about the COVID-19 (<italic>OR</italic>=2.855, <italic>P</italic>&lt;0.001) was a risk factor for anxiety among medical isolated persons during the epidemic, while there was a protective factor in educational level (<italic>OR</italic>=0.656, <italic>P</italic>=0.175). …”
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Predictive Value of NT-proBNP for Functional Outcome of Ischemic Stroke Without Cardiac Disease: A Prospective, Observational Study by Liu R, Chen G, Zhao N, Yue W

“…Both univariate and multivariate logistic analyses indicated that higher NT-proBNP was an independent risk factor for adverse outcomes of ischemic stroke patients at 90 days. …”
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Abnormal Expression of Peripheral Blood Leukocyte Surface Markers in Retinopathy of Prematurity Patients by Guo R, Cheng F, Meng XJ, Fan JM, Lu YL, Ma XH, Qiao X, Li JH

“…This method allowed for the quantification of specific cell subset proportions.Results: A total of 2,110 preterm infants were screened for inclusion in the study. Multivariate logistic regression analysis identified gestational age below 28 weeks, birth weight less than 1,000 g, and neonatal sepsis as independent risk factors for severe ROP. …”
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Impact of interpregnancy weight change on the risk of gestational diabetes mellitus during a second pregnancy in Chinese population: a retrospective cohort study by Ying Wang, Juan Yang, Chang Xu, Yuzhen Liu, Ao Yang, Shilin Zhong

“…Adjusted ORs (aORs) with 95% CIs attained from multivariable logistic regression were used to assess the association between IPWC and s-GDM, in both total subjects and stratified subgroups.Results In the overall analysis, s-GDM was found to be significantly associated with IPWC value (aOR 1.111; 95% CI 1.038 to 1.190) and an IPWC category of ≥3 kg/m² (aOR 1.821; 95% CI 1.197 to 2.772). …”
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核苷（酸）类似物治疗慢性ＨＢＶ感染者至ＨＢＶ ＤＮＡ阴转后ＡＬＴ异常的因素分析

“…【方法】２００６年１月至２０１４年２月期间，回顾加前瞻性随访核苷（酸）类似物初始治疗至ＨＢＶ ＤＮＡ阴转（＜２０ ＩＵ／ｍＬ）后的慢性ＨＢＶ感染者（ｎ ＝ ３８８），对比ＡＬＴ复常者（ｎ＝ ２９８）及异常者［ｎ ＝ ９０；定义为在每１ ～ ３个月的随访间隔中，连续２次以上ＡＬＴ ＞ ４０ Ｕ／Ｌ（男）或 ＞ ３５ Ｕ／Ｌ（女）］的临床特征，使用ｌｏｇｉｓｔｉｃ多因素回归分析ＡＬＴ异常的高危因素。【结果】总随访中位数为４２．０月。两组在人口学和病史数据（性别、年龄、乙肝／肝硬化／肝癌家族史、既往嗜酒史等），基线特征（ＨＢｅＡｇ阳性率、ＡＬＴ、ＡＳＴ、ＨＢＶ ＤＮＡ水平等），核苷（酸）类似物治疗方案构成比，治疗后的病毒学突破和优化治疗率、治疗中的肝癌发生率等，均无显著差异。…”
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Bacterial etiologies, antimicrobial susceptibility profiles and associated factors among patients with otitis media referred to Nekemte Public Health Research and Referral Laborato... by Endalu Tesfaye Guteta, Fedasan Alemu Abdi, Seifu Gizaw Feyisa, Betrearon Sileshi Kinfu, Tadese Bekele Tafesse

“…The data were checked for completeness and consistency, entered into EpiData version 4.6.06 and analyzed by SPSS version 25. Logistic regression analysis was performed to determine the associated factors of otitis media. …”
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Correlation Between the Ratio of Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus:A Cross-Sectional Study by Wang L, Liu L, Luo H, Wu Y, Zhu L

“…The Mantel-Haenszel chi-square test for linear association validated a pronounced positive correlation between the UHR ratio and the incidence of DR (P< 0.001). Binary logistic regression analysis revealed that age, glycated hemoglobin (HbA1c), uric acid (UA), high-density lipoprotein cholesterol (HDL-C), and the UHR ratio were all independent risk factors for the development of DR in patients with type 2 diabetes. …”
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Influencing factors and changing trends of depressive symptoms among middle and junior high school students in Eastern China from 2019 to 2023: a cross-sectional study by Xingchen Zhu, Na An, Zaixiang Tang, Jianping Huang, Qingxin Ren, Yue Wu

“…Furthermore, Trend X 2 Test and Logistic regression was employed to analyze the changing trends of depressive symptoms among the participants. …”
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Association of oxidative balance score with metabolic syndrome and its components in middle-aged and older individuals in the United States by Qu Zhang, Yemei Wu, Bo Luo

“…The OBS was calculated using 16 dietary and four lifestyle factors. Logistic regression was used to assess associations between OBS and MetS. …”
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妊娠期糖尿病孕妇产后糖尿病发生的高危因子分析 by 李璐, 徐安平, 夏勇, 纪玲

“…【结果】复查结果显示，342名GDM孕妇中有27名产后 发生2型糖尿病，发病率高于对照组，差异有统计学意义（P < 0.05），其中GDM Ⅲ组中发病率为45.23%，发病率 高于其他GDM组（P < 0.05）；在发生2型糖尿病的GDM孕妇中，与自身妊娠前和同期未发生2型糖尿病的GDM 孕妇相比，2 h血糖和HbA1c值明显增加，且差异具有统计学意义（P < 0.05）。Logistic回归分析结果显示，GDMⅢ 组别、2 h血糖和HbA1c值，这三种高危因子均是GDM孕妇发生2型糖尿病的危险因素（P < 0.05）。…”
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Anemia, Thrombocytopenia, and Changes in Biochemical Parameters Occurring in Patients with Uncomplicated Plasmodium falciparum Malaria: Data Analysis from Antimalarial Efficacy-Ran... by Khadime Sylla, Roger Tine, Doudou Sow, Souleye Lelo, Annie Abiola, Jean Louis NDiaye, Magatte NDiaye, Kuaku Folly, Léon Amath NDiaye, Oumar Gaye, Babacar Faye

“…Risks and trends were calculated using multivariate logistic random effect models. Results. A total of 720 patients with completed biological data were included in the analysis (320 in the AL arm, 160 in the ASMQ arm, 120 in the DHAPQ arm, and 88 in the ASAQ arm). …”
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Assessment of stress and health conditions among students in the context of the war in Ukraine by Vladimir Potop, Igor Vypasniak, Iryna Ivanyshyn, Vasyl Lutskyi, Iryna Kryventsova, Lyudmila Shesterova, Katarzyna Prusik

“…Correlation analysis was conducted between the overall PSS-10 score and measures of positive and negative affect. A logistic regression model was used to identify predictors of stress. …”
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Atlas of Fshr expression from novel reporter mice by Hongqian Chen, Hui-Qing Fang, Jin-Tao Liu, Shi-Yu Chang, Li-Ben Cheng, Ming-Xin Sun, Jian-Rui Feng, Ze-Min Liu, Yong-Hong Zhang, Clifford J Rosen, Peng Liu

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The effect of GM-CSF and predictors of treatment outcome in pediatric septic shock patients by Zhen-Hao Yu, Gui-Xiang Tian, Yao-Dong Wang, Ting-Yan Liu, Peng Shi, Jia-Yun Ying, Wei-Ming Chen, Yu-Feng Zhou, Guo-Ping Lu, Cai-Yan Zhang

“…We employed univariate and multivariate logistic regression models to assess the influence of GM-CSF on 28-day mortality and identify significant predictors of treatment outcomes. …”
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Can Early Diagnosis of Varices, Regular Praziquantel, and Reduction of Hepatitis Coinfection Reduce Mortality among Patients Attended for Periportal Fibrosis in Northwestern Tanzan... by Daniel W. Gunda, Elizabeth F. Mtui, Semvua B. Kilonzo, Paulina M. Manyiri, David C. Majinge, Humphrey D. Mazigo

“…Cumulative mortality as a major outcome was also determined, and factors associated with increased risk of mortality were assessed by a logistic regression model. Results. In total, 250 participants were included in this analysis. …”
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