Showing 1,161 - 1,180 results of 1,182 for search '"liver diseases"', query time: 0.11s Refine Results
  1. 1161

    Prognostic value of inflammatory markers for all-cause mortality in patients with acute myocardial infarction in the coronary care unit: a retrospective study based on MIMIC-IV dat... by Fen Cao, Jun-jun Jiang, Gui Zhang, Jun Liu, Ping Xiao, Yang Tian, Wei Zhang, Sheng Zhang, Feng Hou, Zhong-Wu Bao, Kun Wu, Yong-zhi Zhu

    Published 2025-01-01
    “…Stratified analyses based on gender and comorbidities showed that the risk of death was significantly increased in male and female patients, with or without diabetes, without cerebral infarction, chronic obstructive pulmonary disease, liver disease, and renal disease in the Q4 group when compared to the Q1 group.ConclusionsNLR is nonlinearly and positively associated with all-cause mortality of AMI patients in the CCU. …”
    Get full text
    Article
  2. 1162

    Systematic identification of secondary bile acid production genes in global microbiome by Yuwei Yang, Wenxing Gao, Ruixin Zhu, Liwen Tao, Wanning Chen, Xinyue Zhu, Mengping Shen, Tingjun Xu, Tingting Zhao, Xiaobai Zhang, Lixin Zhu, Na Jiao

    Published 2025-01-01
    “…Furthermore, we highlighted the associations between secondary bile acids (SBAs) and gastrointestinal and hepatic disorders, including inflammatory bowel disease (IBD), colorectal cancer (CRC), and nonalcoholic fatty liver disease (NAFLD), further elucidating disease-specific alterations in secondary bile acid production genes. …”
    Get full text
    Article
  3. 1163

    A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma by Torsten Diesinger, Alfred Lautwein, Sebastian Bergler, Dominik Buckert, Christian Renz, Radovan Dvorsky, Vyacheslav Buko, Siarhei Kirko, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Felicitas Genze, Berthold Büchele, Thomas Simmet, Martin Haslbeck, Kai Masur, Thomas Barth, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner

    Published 2021-01-01
    “…Cytochrome P450 2E1 (CYP2E1) is a key target protein in the development of alcoholic and nonalcoholic fatty liver disease (FLD). The pathophysiological correlate is the massive production of reactive oxygen species. …”
    Get full text
    Article
  4. 1164

    The mediating role of social support in self-management and quality of life in patients with liver cirrhosis by Ying Zhang, LeYao Xiao, Qian Liu, XinYi Zhang, MingDan Li, YaLi Xu, Mei Dai, Fei Zhao, YouShu Shen, Jordan Tovera Salvador, Ping Yang

    Published 2025-02-01
    “…The patients were evaluated using a demographic questionnaire, the Self-Management Behavior Scale for Liver Cirrhosis Patients, the Social Support Rating Scale (SSRS), the Chronic Liver Disease Questionnaire (CLDQ), and the Royal Free Hospital Nutritional Prioritizing Tool (RFH-NPT). …”
    Get full text
    Article
  5. 1165

    Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome by Fabien Robert, Feriel Benchenouf, My Ngoc Ha, Alessandra Cuomo, Mina Ottaviani, Maxime Surbier, Raphaël Thuillet, Corinne Normand, Florent Dumont, Céline Verstuyft, Frederic Fiore, Frederic Guinut, Marc Humbert, Audrey Coilly, Emmanuel Gonzales, Olivier Sitbon, Ly Tu, Christophe Guignabert, Laurent Savale

    Published 2025-03-01
    “…Methods: Circulating PlGF levels were measured in 64 controls and 137 patients with liver disease, with or without HPS. Two rat models, common bile duct ligation (CBDL) and long-term partial portal vein ligation (PPVL), were used. …”
    Get full text
    Article
  6. 1166

    Factors influencing in-hospital mortality for salvage percutaneous transjugular intrahepatic portosystemic shunting in cirrhotic patients with recalcitrant variceal bleeding after... by J E J Krige, E G Jonas, M Setshedi, S J Beningfield, U K Lotze, M M Bernon, S Burmeister, J C Kloppers

    Published 2023-12-01
    “…On bivariate analysis, factors associated with death were Child-Pugh (C-P) score ≥10 (p=0.006), sodium Model for End-stage Liver Disease (MELD-Na) score ≥22 (p<0.001), ≥8 units of blood transfused (p<0.001), Sengstaken-Blakemore balloon tube placement (p<0.001), endotracheal intubation (p<0.001), inotropic support (p<0.001) and endoscopically uncontrolled bleeding (p<0.001). …”
    Get full text
    Article
  7. 1167
  8. 1168

    The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury by Xiaoxiao Luo, Dongyang Liu, Cuicui Li, Jia Liao, Wuyang Lv, Yuchen Wang, Ruxue Diao, Yingyu Jin

    Published 2025-01-01
    “…Multivariate regression identified that the SOFA score, PT, ΔScr, Tbil, chronic liver disease, and Vasopressor use as independent risk factors for persistent severe SA-AKI (P < 0.05). …”
    Get full text
    Article
  9. 1169

    Noninvasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B or C by Contrast-Enhanced Magnetic Resonance Imaging by René Hako, Pavol Kristian, Peter Jarčuška, Ivana Haková, Ivana Hockicková, Ivan Schréter, Martin Janičko

    Published 2019-01-01
    “…This test correctly identified 42,1% of patients in the control group (presumed F0 fibrosis without liver disease). Spearman's rank correlation coefficient (r = 0,86, P < .001) confirmed high agreement of biopsy and MR Triple test. …”
    Get full text
    Article
  10. 1170
  11. 1171
  12. 1172

    High-fat diet-induced liver injury in Channa argus through lipid metabolism, anti-oxidative status, apoptosis, and inflammation by Jiaxin Tian, Ying Li, Jiwu Wan, Zhinan Yang, Guiqin Wang

    Published 2025-04-01
    “…Channa argus, a valuable fish species in southern Chinese aquaculture, is susceptible to fatty liver disease. To investigate the mechanism of liver injury in C. argus caused by a high-fat diet, fish were fed diets with varying fat levels: control (CK, 11 % fat), L16 (16 % fat), and L22 (22 % fat) for 90 days. …”
    Get full text
    Article
  13. 1173

    Alcohol abuse in gastroenterological patients by M. V. Mayevskaya, I. G. Bakulin, A. A. Chirkov, Ye. O. Lyusina, V. D. Lun’Kov

    Published 2018-08-01
    “…Thirty-two percent of patients had liver cirrhosis of toxic and viral etiology, 18% had chronic toxic and viral hepatitis, 11% - non-alcoholic fatty liver disease and various biliary diseases respectively, chronic pancreatitis and chronic gastritis subgroups represented 6% of all patients each, irritable bowel syndrome and gastroesophageal reflux disease - 4% each, primary biliary cirrhosis, hepatocellular carcinoma, stomach and duodenal peptic ulcer disease - 2%. …”
    Get full text
    Article
  14. 1174

    A new prognostic model based on serum apolipoprotein AI in patients with HBV-ACLF and acutely decompensated liver cirrhosis by Ruidong Mo, Zhenglan Zhang, Yanmei Zhou, Yue Wang, Pengbo Yin, Chenxi Zhang, Haoshuang Fu, Cong Qian, Xiaogang Xiang, Rongkun Yin, Qing Xie

    Published 2025-02-01
    “…Results In the cohort, the negatively correlation was found between the Model for End-Stage Liver Disease (MELD) score and serum apoAI levels (r = -0.7946, P < 0.001). …”
    Get full text
    Article
  15. 1175

    CPEB4 modulates liver cancer progression by translationally regulating hepcidin expression and sensitivity to ferroptosis by M. Eugenia Delgado, Salvador Naranjo-Suarez, Marta Ramírez-Pedraza, Beatriz I. Cárdenas, Carmen Gallardo-Martínez, Alexandra Balvey, Eulalia Belloc, Judit Martín, Mark Boyle, Raúl Méndez, Mercedes Fernandez

    Published 2025-03-01
    “…Impact and implications:: This study addresses the pressing need for improved therapies in liver cancer, particularly given its increasing prevalence linked to obesity and metabolic-associated fatty liver disease. By uncovering the role of the RNA-binding protein cytoplasmic polyadenylation element binding protein 4 (CPEB4) in modulating iron regulation and cancer cell sensitivity to ferroptosis, our research highlights a new translational mechanism with potential therapeutic relevance. …”
    Get full text
    Article
  16. 1176

    Circulating Isthmin-1 Levels and Their Relationship with Diabetes and Metabolic Diseases in Kuwaiti Adults by Eman Alshawaf, Sulaiman K. Marafie, Mohamed Abu-Farha, Ahmed N. Albatineh, Tahani Alramah, Aldana Albuhairi, Yafa Al Qassar, Reem Zinoun, Rawan Shalabi, Sarah Behbehani, Dalal Mohammed, Fahad Alajmi, Mohammed A. Abdalla, Ebaa Al-Ozairi, Mohammad Shehab, Muhammad Abdul-Ghani, Fahd Al-Mulla, Jehad Abubaker

    Published 2025-01-01
    “…Isthmin-1 (Ism1) has recently emerged as a potential marker of metabolic health and was shown in animal studies to associate with metabolic-associated fatty liver disease (MAFLD). In this study, we aimed to investigate the circulatory levels of Ism1 in individuals with obesity compared to non-obese individuals and evaluate their association with insulin resistance, MAFLD, and T2D. …”
    Get full text
    Article
  17. 1177

    miR124a-3p inhibitor alleviates AFB1-induced hepatoxicity via targeting chicken glucocorticoid receptor mRNA by Mindie Zhao, Liang Chen, Yulan Zhao, Jie Liu, Huimin Chen, Ruqian Zhao

    Published 2025-03-01
    “…This study highlights GR and its miRNA as potential therapeutic targets for AFB1-induced liver disease, providing new insights into therapeutic strategies to mitigate the harmful effects of AFB1 exposure in poultry.…”
    Get full text
    Article
  18. 1178

    Liver Elastography for Liver Fibrosis Stratification: A Comparison of Three Techniques in a Biopsy-Controlled MASLD Cohort by Antonio Liguori, Giorgio Esposto, Maria Elena Ainora, Irene Mignini, Raffaele Borriello, Linda Galasso, Mattia Paratore, Maria Cristina Giustiniani, Laura Riccardi, Matteo Garcovich, Antonio Gasbarrini, Luca Miele, Maria Assunta Zocco

    Published 2025-01-01
    “…<b>Background:</b> The aim of this study was to investigate the accuracy in fibrosis staging of a novel shear wave elastography (SWE) device (S-Shearwave Imaging by Samsung) and a previously validated 2D-SWE by Supersonic Imagine (SSI) in patients with biopsy proven metabolic dysfunction-associated steatotic liver disease (MASLD). <b>Methods:</b> This prospective study included 75 consecutive patients with MASLD who underwent liver biopsy for suspected MASH. …”
    Get full text
    Article
  19. 1179

    Sex differences in murine MASH induced by a fructose-palmitate-cholesterol-enriched diet by Lakshmi Arivazhagan, Sofie Delbare, Robin A. Wilson, Michaele B. Manigrasso, Boyan Zhou, Henry H. Ruiz, Kaamashri Mangar, Ryoko Higa, Emily Brown, Huilin Li, Michael J. Garabedian, Ravichandran Ramasamy, Kathryn J. Moore, Edward A. Fisher, Neil D. Theise, Ann Marie Schmidt

    Published 2025-02-01
    “…Background &amp; Aims: Metabolic syndrome-associated steatotic liver disease (MASLD) and metabolic syndrome-associated steatohepatitis (MASH) have global prevalence rates exceeding 25% and 3-6%, respectively. …”
    Get full text
    Article
  20. 1180