Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females by Gerald Y. Minuk, Lloyd R. Sutherland, S. Chris Pappas, James K. Kelly, Sue E. Martin

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Metastatic Hepatocellular Carcinoma in a Patient with Crohn’s Disease Treated with Azathioprine and Infliximab: A Case Report and Literature Review by Kyle J. Fortinsky, Ali Alali, Khursheed Jeejeebhoy, Sandra Fischer, Morris Sherman, Scott Fung

“…The patient had no history of liver disease and a complete autoimmune and viral workup was unremarkable. …”
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SURGICAL RISK ASSESSMENT IN PATIENTS WITH LIVER CIRRHOSIS – A LITERATURE REVIEW by Elina Merashka

“…For this purpose, there are multiple classification and scoring systems for assessment – ​​Child-Pugh – Turcotte (CPT), Model of end-stage liver disease (MELD), Model of end-stage liver disease – Na (MELD – Na), Albumin – Bilirubin score (ALBI), each with specific indications for clinical use. …”
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The Liver That Cured Christmas: Case Report of Orthotopic Liver Transplant in a Patient with Hemophilia B by Jesse E. Harris, Jonathan L. Balk, Constance M. Mobley, Kirk Heyne

“…Herein, we discuss a case of a 39-year-old male with hemophilia B, who developed end-stage liver disease secondary to nonalcoholic steatohepatitis, that underwent orthotopic liver transplantation (OLT) as a curative means for his liver disease and coagulation disorder. …”
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Vibrio vulnificus Septicemia after Handling Tilapia Species Fish: A Canadian Case Report and Review by Donald C Vinh, Samira Mubareka, Bunmi Fatoye, Pierre Plourde, Pamela Orr

“…Primary septicemia is often fatal, principally affecting persons with chronic liver disease.…”
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Innate Immune Cells in Liver Inflammation by Evaggelia Liaskou, Daisy V. Wilson, Ye H. Oo

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Posttransplant Metabolic Syndrome by M. Shadab Siddiqui, Richard K. Sterling

“…In addition to cardiovascular disease, the presence of MS is also closely associated with other comorbidities including nonalcoholic fatty liver disease (NAFLD). The prevalence of MS in patients with cirrhosis and end-stage liver disease is not well established and difficult to ascertain. …”
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Prevalence of Nonalcoholic Steatohepatitis and Associated Fibrosis Stages Among US Adults Using Imaging-Based vs Biomarker-Based Noninvasive Tests by Jesse Fishman, Tom O'Connell, Christina M. Parrinello, Jonathan J. Woolley, Eric Bercaw, Michael R. Charlton

“…**Introduction:** Nonalcoholic fatty liver disease (NAFLD) is believed to be the most common chronic liver disease worldwide. …”
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Complementary and Alternative Medicine Use by Patients Chronically Infected with Hepatitis C Virus by Colin P White, Gerilynn Hirsch, Sunil Patel, Fatin Adams, Kevork M Peltekian

“…The use of CAM is also popular in patients with chronic liver disease but is not well documented. The extent of use of CAM in chronic hepatitis C virus (HCV) infected patients was determined, and the demographic and clinical data between users and nonusers of CAM was compared.…”
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A Meta-Analysis of Nutritional Supplementation for Management of Hospitalized Alcoholic Hepatitis by Ramy Antar, Phil Wong, Peter Ghali

“…BACKGROUND: Alcoholic liver disease (ALD) is associated with a high risk of morbidity and mortality. …”
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Iron depletion in “metabolic fatty liver syndromes”: a strong biological rationale with disappointing liver outcomes by Amedeo Lonardo

“…Nonalcoholic fatty liver disease (NAFLD), its more rapidly progressive steatohepatitic variant [nonalcoholic steatohepatitis, (NASH)], and the recently defined metabolic dysfunction-associated fatty liver disease (MAFLD) may be collectively alluded to as “metabolic fatty liver syndromes” (MFLS). …”
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Management of Hepatic Encephalopathy by G. Wright, A. Chattree, R. Jalan

“…Hepatic encephalopathy (HE), the neuropsychiatric presentation of liver disease, is associated with high morbidity and mortality. …”
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Motion – The Available Treatments for Hepatitis C Are Cost Effective: Arguments against the Motion by W Ray Kim

“…Available cohortbased studies suggest that only a relative minority of patients develop significant liver disease, such as cirrhosis and/or hepatocellular carcinoma. …”
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Liver Cirrhosis: Evaluation, Nutritional Status, and Prognosis by Hiroki Nishikawa, Yukio Osaki

“…Chronic hepatitis C virus infection is the major cause of chronic liver disease. Liver cirrhosis (LC) results from different mechanisms of liver injury that lead to necroinflammation and fibrosis. …”
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A Comprehensive Updated Review of Pharmaceutical and Nonpharmaceutical Treatment for NAFLD by Newaz Hossain, Pushpjeet Kanwar, Smruti R. Mohanty

“…Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the western world with prevalence of 20–33%. …”
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An Overview of In Vitro Models of Alcohol‐Related Hepatocellular Carcinoma by Anoïsia Courtois, Sophie Gérard, Damien Esparteiro, Eric Nguyen‐Khac, Ingrid Marcq, Grégory Fouquet

“…ABSTRACT Background Chronic and excessive alcohol consumption is the leading cause of death due to chronic liver disease. Alcohol‐related liver disease (ALD) encompasses a broad spectrum of clinical and pathological features, ranging from asymptomatic and reversible pathologies to hepatocellular carcinoma (HCC), a highly prevalent and deadly liver cancer. …”
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Current Treatment Approaches to HCC with a Special Consideration to Transplantation by N. Bhardwaj, M. T. P. R. Perera, M. A. Silva

“…Resectable patients with early HCC and underlying liver disease are however increasingly being considered for transplantation because of potential for better disease-free survival and resolution of underlying liver disease, although this approach is limited by the availability of donor livers, especially in resectable patients. …”
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Short-term abstinence from alcohol and changes in cardiovascular risk factors, liver function tests and cancer-related growth factors: a prospective observational study by Gautam Mehta, Rajiv Jalan, Matteo Rosselli, James Maurice, Stewart Macdonald, Alexandra Cronberg, Tanya Khera-Butler, Colin Sumpter, Safa Al-Khatib, Anjly Jain, Christos Charalambous, Amir Gander, Cynthia Ju, Talay Hakan, Roy Sherwood, Devaki Nair, Kevin P Moore

“…Exclusion criteria were known liver disease or alcohol dependence.Primary and secondary outcome measures The primary outcome was change in insulin resistance (homeostatic model assessment (HOMA) score). …”
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Direct targeting of risk factors significantly increases the detection of liver cirrhosis in primary care: a cross-sectional diagnostic study utilising transient elastography by Guruprasad P Aithal, Indra Neil Guha, Stephen D Ryder, Emilie A Wilkes, David J Harman, Martin W James, Matthew Jelpke, Dominic S Ottey, Timothy R Card

“…Objectives To assess the feasibility of a novel diagnostic algorithm targeting patients with risk factors for chronic liver disease in a community setting.Design Prospective cross-sectional study.Setting Two primary care practices (adult patient population 10 479) in Nottingham, UK.Participants Adult patients (aged 18 years or over) fulfilling one or more selected risk factors for developing chronic liver disease: (1) hazardous alcohol use, (2) type 2 diabetes or (3) persistently elevated alanine aminotransferase (ALT) liver function enzyme with negative serology.Interventions A serial biomarker algorithm, using a simple blood-based marker (aspartate aminotransferase:ALT ratio for hazardous alcohol users, BARD score for other risk groups) and subsequently liver stiffness measurement using transient elastography (TE).Main outcome measures Diagnosis of clinically significant liver disease (defined as liver stiffness ≥8 kPa); definitive diagnosis of liver cirrhosis.Results We identified 920 patients with the defined risk factors of whom 504 patients agreed to undergo investigation. …”
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Primary sclerosing cholangitis by Marina G Silveira, Keith D Lindor

“…Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, resulting in end-stage liver disease and reduced life expectancy. …”
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