Odevixibat treatment in a child with hypoplastic left heart syndrome and severe cholestatic pruritus: a case report by Rainer Ganschow, Christof Maucksch, Peter Rauschkolb, Martin B. E. Schneider

“…Odevixibat is an ileal bile acid transporter inhibitor under investigation for the treatment of cholestatic liver diseases. Here, we describe the effects of odevixibat treatment in a pediatric patient with congenital heart disease and severe cholestatic pruritus. …”
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Coinfection of Hepatitis B and C Viruses and Risk of Hepatocellular Carcinoma: Systematic Review and Meta-analysis by Abdullah A. Awadh, Abdulrahman A. Alharthi, Basil A. Alghamdi, Seraj T. Alghamdi, Mohammed K. Baqays, Ibrahim S. Binrabaa, Israa A. Malli

“…The hepatitis B virus-hepatitis C virus (HBV-HCV) coinfection leads to a faster progression to advanced liver diseases and higher hepatocellular carcinoma (HCC) risk than monoinfection. …”
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Incidence, Antibiogram, and Comorbid Conditions of Nontyphoidal Salmonella Infections Before and After the COVID-19 Outbreak: A Retrospective, Cross-sectional Study by Kundoly V. Suseela, Aiswariya Alex, Subi Das, V. Geethalakshmi

“…Malignancy was the leading comorbid condition (11.91%) followed by chronic liver diseases (10.31%). Conclusions: A significant rise in NTS diarrheal cases was detected following the COVID-19 outbreak. …”
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Hyponatremia In Ischemic Stroke Patients And Its Relationship To Clinical Outcomes In Such Patients by Maria Zafar, Aneza Jalil, Amber Ghaffer, Mahnoor Yousaf, Sadia Batool

“…All patients with hemorrhagic stroke, having previous history of stroke, recent head injury, CNS infection, already using sodium lowering diuretics, or with end-stage diseases like Heart failure, chronic kidney disease and decompensated liver diseases were excluded from the study. Primary outcome measures were in-hospital mortality and duration of hospital stay (LOS). …”
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Outer Membrane Vesicles Derived from Adherent-Invasive Escherichia coli Induce Inflammatory Response and Alter the Gene Expression of Junction-Associated Proteins in Human Intestin... by Bahareh Nadalian, Banafsheh Nadalian, Mohammad Reza Zali, Abbas Yadegar

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Rheumatoid Arthritis Effects on Kidney and Liver and their Correlations with CDAI by Tamara Salman Mohammed, Raya Ezat Maroof, Ali Hussein Al-Hafidh

“…Persistent usage of anti-rheumatic drugs has several side effects, which may cause heart, kidney, or liver diseases. This study aims to assess the influence of RA duration on kidney and liver enzymes and study the correlation between these enzyme levels and RA disease activity (CDAI). …”
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US multicenter outcomes of endoscopic ultrasound-guided gallbladder drainage with lumen-apposing metal stents for acute cholecystitis by Yakira David, Gaurav Kakked, Bradley Confer, Ruchit Shah, Harshit Khara, David L Diehl, Matthew Richard Krafft, Sardar M Shah-Khan, John Y Nasr, Petros Benias, Arvind Trindade, Thiruvengadam Muniraj, Harry Aslanian, Prabhleen Chahal, John Rodriguez, Douglas G Adler, Jason Dubroff, Rabi De Latour, Demetrios Tzimas, Lauren Khanna, Gregory Haber, Adam J Goodman, Nicholas Hoerter, Nishi Pandey, Mena Bakhit, Thomas E. Kowalski, David Loren, Austin Chiang, Alexander Schlachterman, Jose Nieto, Ameya Deshmukh, Yervant Ichkhanian, Mouen A. Khashab, Maan El Halabi, Richard S. Kwon, Anoop Prabhu, Ariosto Hernandez-Lara, Andrew Storm, Tyler M. Berzin, John Poneros, Amrita Sethi, Tamas A Gonda, Vladimir Kushnir, Natalie Cosgrove, Daniel Mullady, Abdullah Al-Shahrani, Lionel D'Souza, Jonathan Buscaglia, Juan Carlos Bucobo, Vineet Rolston, Prashant Kedia, Franklin Kasmin, Satish Nagula, Nikhil A Kumta, Christopher DiMaio

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Phenolic Compounds from Water-Ethanol Extracts of Tetrapleura tetraptera Produced in Cameroon, as Potential Protectors against In Vivo CCl4-Induced Liver Injuries by Peter William Kemewele Saague, Bruno Moukette Moukette, Jacques Romain Njimou, Prosper Cabral Nya Biapa, Francine Nzufo Tankeu, Vicky Joseline Ama Moor, Constant Anatole Pieme, Jeanne Yonkeu Ngogang

“…Background. Liver diseases are a global health problem. Medicinal plants are being increasingly used to manage a wide variety of diseases including liver disorders. …”
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Investigating the Effect and Potential Mechanism of Rhamnetin 3-<i>O</i>-α-Rhamnoside on Acute Liver Injury In Vivo and In Vitro by Dandan Deng, Borong Zhao, Hong Yang, Songsong Wang, Ziying Geng, Jiangtao Zhou, Guane Yang, Liwen Han

“…., which has been used for treating liver diseases in China. However, the protective effect of ARR on the liver has not been reported. …”
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Gene therapy by hepatocyte growth factor results in regression of experimental liver fibrosis by N. A. Dzhoyashvili, N. I. Kalinina, I. B. Beloglazova, Z. I. Tsokolayeva, P. I. Makarevich, Yu. L. Perov, Ye. V. Parfenova, V. A. Tkachuk

“…Obtained results allow to consider gene therapy by hepatocyte growth factor in composition of non-viral vectors as one of perspective methods of treatment of chronic liver diseases.…”
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Factors associated with pulmonary complications after hepatectomy and establishment of nomogram: A real-world retrospective study by Kunyu Han, Hui Liu, Ruiping Bai, Jiarui Li, Linjuan Zhang, Rui An, Di Peng, Jiamin Zhao, Mengwen Xue, Xin Shen

“…Background and Aims: Hepatectomy is currently the most effective way to treat liver diseases, and its safety has observably improved. …”
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Promotora intervention for metabolic and mental health to reduce type 2 diabetes risk: a pilot randomized controlled trial by Maria C. Vargas, Joshua B. Katz, Azucena Lopez, Arturo Carrillo, Dyanna L. Gregory, Matthew J. O’Brien

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HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients’ clinical stage by Lucile Dumolard, Theophile Gerster, Florent Chuffart, Thomas Decaens, Marie-Noelle Hilleret, Sylvie Larrat, Philippe Saas, Evelyne Jouvin-Marche, David Durantel, Patrice N. Marche, Zuzana Macek Jilkova, Caroline Aspord

“…Infected individuals who fail to control the viral infection develop chronic hepatitis B and are at risk of developing life-threatening liver diseases, such as cirrhosis or liver cancer. Dendritic cells (DCs) play important roles in the immune response against HBV but are functionally impaired in patients with chronic hepatitis B. …”
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Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study by Johan Burisch, Lene Terslev, Mikkel Østergaard, Annette Bøjer Jensen, Frank Krieger Jensen, Flemming Bendtsen, Charlotte Wiell, Mohamed Attauabi, Klaus Theede, Viktoria Fana, Hartwig Roman Siebner, Henrik S Thomsen, Jakob M Møller, Simon Francis Thomsen, Gorm Roager Madsen, Anne Vibeke Wewer, Rune Wilkens, Johan Ilvemark, Nora Vladimirova, Sanja Bay Hansen, Yousef Jesper Wirenfeldt Nielsen, Helene Andrea Sinclair Ingels, Trine Boysen, Jacob T Bjerrum, Christian Jakobsen, Maria Dorn-Rasmussen, Sabine Jansson, Yiqiu Yao, Ewa Anna Burian, Frederik Trier Møller, Kristina Bertl, Andreas Stavropoulos, Jakob B Seidelin

“…Fibroscans and dual-energy X-ray absorptiometry scans will be performed to monitor occurrence and course of chronic liver diseases, osteopenia and osteoporosis.Ethics and dissemination This study has been approved by Ethics Committee of the Capital Region of Denmark (approval number: H-20065831). …”
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Ultrasound radiomics-based logistic regression model for fibrotic NASH by Fei Xia, Wei Wei, Junli Wang, Yuhe Wang, Kun Wang, Chaoxue Zhang, Qiwei Zhu

“…To forecast the non-alcoholic steatohepatitis (NASH) probability accompanied by significant fibrosis, we propose to develop and validate a nomogram liver imaging reporting and data system, providing robust evidence for preventing and treating clinical liver diseases. Methods The study used SD rats to create a model of hepatic steatosis and fibrosis by feeding them a high-fat diet and injecting Ccl4 subcutaneously. …”
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Liver Fibrosis Scores and Hospitalization, Mechanical Ventilation, Severity, and Death in Patients with COVID-19: A Systematic Review and Dose-Response Meta-Analysis by Menglu Liu, Kaibo Mei, Ziqi Tan, Shan Huang, Fuwei Liu, Chao Deng, Jianyong Ma, Peng Yu, Xiao Liu

“…For patients with COVID-19 at admission, especially for those with coexisting chronic liver diseases, assessment of liver fibrosis scores might be useful for identifying high risk of developing severe COVID-19 cases and worse outcomes.…”
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Changes in the Structural and Functional Albumin Properties in Patients with Decompensated Liver Cirrhosis by A. A. Turkina, M. V. Maevskaya, M. S. Zharkova, V. T. Ivashkin

“…The control group consisted of 12 healthy volunteers, comparable in gender and age, without liver diseases. To assess the structural and functional ability, serum albumin was analyzed by EPR spectroscopy.Results. …”
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Oncogene mutations in non-small cell lung cancer patients in Iran: a study of their association with programmed death ligand-1 expression by Zahra Abrehdari-Tafreshi, Majid Pirestani, Zahra Mosaferi, Nasser Rakhshani, Ehsan Arefian

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Role of the Aspartate Transaminase and Platelet Ratio Index in Assessing Hepatic Fibrosis and Liver Inflammation in Adolescent Patients with HBeAg-Positive Chronic Hepatitis B by Yu Zhijian, Li Hui, Yao Weiming, Lin Zhanzhou, Chen Zhong, Zheng Jinxin, Wang Hongyan, Deng Xiangbin, Yang Weizhi, Li Duoyun, Liu Xiaojun, Deng Qiwen

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Caffeine supplement, inflammation, and hepatic function in cirrhotic patients: A randomized, placebo- controlled, clinical trial by Seyed Ali Abbas-Hashemi, Zahra Yari, Behzad Hatami, Amir Anushiravani, Shadi Kolahdoozan, Ali Zamanian, Nadia Akbarzadeh, Azita Hekmatdoost

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