Multi-target regulatory effects of rhaponticin in a rat model of hepatic fibrosis revealed by non-targeted metabolomics by Min Yang, Dihua Jiang, Longfei Huang, Tao Zhang, Wenfen Guo, Wenyan Lin, Jiali Zhao, Yunsheng Wei, Lang Peng, Yong-Jia Hao, Ying Zhou

“…IntroductionHepatic fibrosis (HF), a progressive chronic liver disease, is a serious threat to global public health. …”
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Cardiac Failure after Liver Transplantation Requiring a Biventricular Assist Device by Rita Jermyn, Eiei Soe, David D’Alessandro, Julia Shin, William Jakobleff, Daniel Schwartz, Milan Kinkhabwala, Paul J. Gaglio

“…This case highlights the importance of preoperatively recognizing extrahepatic iron deposition in patients referred for liver transplantation irrespective of etiology of liver disease as this may prevent postoperative complications.…”
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Prevalence of advanced hepatic fibrosis and individualization of associated risk factors by Bayesian analysis in MASLD patients in French cardio-metabolic health networks. by Michel Doffoel, Frédéric Chaffraix, Archia Chahard, Dominique Gras, Odile Bonomi, Corinne Bildstein, Simona Tripon, Maude Royant, Nicolas Meyer

“…The aim of this study was to determine the prevalence of advanced hepatic fibrosis and to individualize using Bayesian analysis its associated risk factors in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) being cared for in three Alsatian cardio-metabolic health networks in the North East of France. …”
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Quality of Life of Patients with Liver Cirrhosis by María Belén Alvarado Villavicencio, Evelyn Carolina Betancourt Rubio, Luis Roberto Villamarín Ponce

“…<strong>Foundation: l</strong>iver cirrhosis is a chronic liver disease characterized by the formation of scar tissue and a decrease in normal liver function. …”
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Apelin Serum Level in Egyptian Patients with Chronic Hepatitis C by Hala O. El-Mesallamy, Nadia M. Hamdy, Hanan H. Rizk, Abdel-Rahman El-Zayadi

“…Highlighting the apelin system would present a new therapeutic target for liver disease. Apelin; endogenous ligand for the orphan receptor APJ, was recently suggested to be associated with fibrosis progression and cirrhosis in addition to insulin resistance (IR) and inflammation. …”
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New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications by Eva Sticova, Milan Jirsa, Joanna Pawłowska

“…Phenotypic manifestation is highly variable, ranging from progressive familial intrahepatic cholestasis (PFIC)—with onset in early infancy and progression to end-stage liver disease—to a milder intermittent mostly nonprogressive form known as benign recurrent intrahepatic cholestasis (BRIC). …”
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Systematic Framework to Predict Early-Stage Liver Carcinoma Using Hybrid of Feature Selection Techniques and Regression Techniques by Marium Mehmood, Nasser Alshammari, Saad Awadh Alanazi, Fahad Ahmad

“…The liver is the human body’s mandatory organ, but detecting liver disease at an early stage is very difficult due to the hiddenness of symptoms. …”
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Noncoding RNAs Associated with PPARs in Etiology of MAFLD as a Novel Approach for Therapeutics Targets by Fatemeh Kazeminasab, Maryam Baharlooie, Kamran Ghaedi

“…Metabolic associated fatty liver disease (MAFLD) is a complex disease that results from the accumulation of fat in the liver. …”
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Diagnostic Imaging of Canine Hepatobiliary Affections: A Review by Vijay Kumar, Adarsh Kumar, A. C. Varshney, S. P. Tyagi, M. S. Kanwar, S. K. Sharma

“…The aim of clinicopathological evaluation of hepatobiliary affections is to identify and characterize hepatic damage and dysfunction, identify possible primary causes of secondary liver disease, differentiate causes of icterus, evaluate potential anaesthetic risks, assess prognosis and response to xenobiotics, and monitor response to therapy. …”
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Western Diet Decreases Hepatic Drug Metabolism in Male LDLr−/−ApoB100/100 Mice by Markus Koponen, Jaana Rysä, Anna-Kaisa Ruotsalainen, Olli Kärkkäinen, Risto O. Juvonen

“…Consumption of a Western diet is an important risk factor for several chronic diseases including nonalcoholic fatty liver disease (NAFLD), but its effect on the xenobiotic metabolizing enzyme activities in the liver has been studied incompletely. …”
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Wilson’s Disease: Diagnosis of Wilson’s Disease in Ethiopian Young Sisters by Nebiyu Bekele, Frew Ewnetu, Tigest Hailu, Zerubabel Tegegne, Abilo Tadesse

“…Both siblings had visible ocular Kayser–Fleischer rings, low serum ceruloplasmin level and increased urinary copper content, ultrasound-evidenced cirrhotic liver disease, and axial T2-weighted MRI hyperintensities in basal ganglia, thalamus, and brainstem (midbrain and pons). …”
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Prolonged Serum Alanine Aminotransferase Elevation Associated with Isotretinoin Administration by Roya S. Nazarian, Elizabeth Zheng, Caroline Halverstam, Steven R. Cohen, Allan W. Wolkoff

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Methimazole-Induced Cholestatic Jaundice: A Rare Case and Literature Review by Ahmed Mohamed Nefzi, Dhouha Cherif, Habiba Dabbebi, Haythem Yacoub, Hajer Hassine, Hela Kchir, Khadija Bellil, Nadia Maamouri

“…Concomitant causes of liver disease were ruled out. The treatment was discontinued, and a switch to corticosteroid therapy with a regimen of radioactive iodine sessions was initiated. …”
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Prevalence and associated factors of MAFLD in adults with type 2 diabetes. by Yifei He, Feng Xiao, Bin Yi, Jin Lu

“…Among the 1044 T2DM patients with metabolically associated fatty liver disease (MAFLD), 29.5% developed hepatic fibrosis (LSM>8 kPa). …”
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Deep sequencing-derived Metagenome Assembled Genomes from the gut microbiome of liver transplant patients by Goutam Banerjee, Suraya Rahman Papri, Hai Huang, Sanjaya Kumar Satapathy, Pratik Banerjee

“…Abstract Recurrence of metabolic dysfunction-associated steatotic liver disease (MASLD) after liver transplantation (LT) is a continuing concern. …”
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Safety Profile of Liver FibroScan in Patients with Cardiac Pacemakers or Implantable Cardioverter-Defibrillators by Yin Chan, Stephanie Pranke, Farid Rashidi, Shravan Nosib, Lawrence Worobetz

“…Emerging evidence suggests that nonalcoholic fatty liver disease (NAFLD) is associated with coronary artery diseases and arrhythmias. …”
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Demographics, aetiology and outcome of paediatric acute liver failure in Singapore by Fang Kuan Chiou, Veena Logarajah, Christopher Wen Wei Ho, Lynette Suk-Hui Goh, Sivaramakrishnan Venkatesh Karthik, Marion Margaret Aw, Kong Boo Phua

“…PALF was defined by: absence of chronic liver disease; biochemical evidence of acute liver injury; and coagulopathy, non-correctible by vitamin K, defined as prothrombin time (PT) ≥20 seconds or international normalised ratio (INR) ≥2.0 regardless of hepatic encephalopathy (HE) or PT ≥15 seconds or INR ≥1.5 in the presence of HE. …”
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Peritoneal Tuberculosis in an Immunocompetent, Unknown Risk Patient by Yutaka Tomizawa, Emmanuelle B. Yecies, Fiona E. Craig, Adam Sohnen

“…Physical examination was notable for new onset ascites, but no superficial lymphadenopathy or stigmata of chronic liver disease was found. CT scan demonstrated enlarged mesenteric lymph nodes, and prominent retroperitoneal lymph nodes along with moderate ascites and omental infiltration. …”
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Plasma α-Glutathione S-Transferase Evaluation in Patients with Acute and Chronic Liver Injury by Jolanta Czuczejko, Celestyna Mila-Kierzenkowska, Karolina Szewczyk-Golec

“…We aimed to investigate the significance of α-GST evaluation in monitoring of liver injury in acute and chronic liver diseases. 20 healthy volunteers and 52 patients were included in the study. …”
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Correlation between hepatic steatosis severity diagnosed by ultrasound and metabolic indexes in elderly patients with MAFLD by Zhitang Liang, Renhao Huang, Lingyun Zhang

“…ObjectiveTo explore the connection between metabolic parameters and the severity of hepatic steatosis determined through ultrasound in elderly individuals with metabolic dysfunction-associated fatty liver disease (MAFLD).Methods4,663 senior individuals who were 65 years of age or older were included in this research. …”
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