Diagnostic Challenges in Primary Hepatocellular Carcinoma: Case Reports and Review of the Literature by Monika Pazgan-Simon, Sylwia Serafinska, Justyna Janocha-Litwin, Krzysztof Simon, Jolanta Zuwala-Jagiello

“…Patients with chronic liver disease, presenting with inconclusive and changeable test results, constitute a separate problem. …”
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Autoimmune hepatitis: new in diagnostics, a pathogenesis and treatment by Ye. N. Shirokova, K. V. Ivashkin, V. T. Ivashkin

“…AIH is a chronic inflammatory liver disease which is characterized by destruction of terminal plate by mononuclear infiltrate (interface hepatitis) according to histological investigation, hypergammaglobulinemia and production of autoantibodies. …”
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Efficacy of nucleoside analogues for hepatitis B virus-related liver failure: A network meta-analysis by Wu Jian, Yin Fang, Zhou Xinmin

“…The highest two- and three-month survival rate was recorded for patients using tenofovir. The end-stage liver disease (MELD) score and mortality in patients undergoing tenofovir treatment were the lowest. …”
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Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility by Rohan Patel, Fareeha Alavi, Susel Ortega, Ajsza Matela

“…Upon a detailed investigation, the patient did not have evidence of underlying liver disease or any other risk factors to explain her presentation. …”
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SUPPRESSION OF SUBGENOMIC HEPATITIS C VIRUS RNA REPLICON REPLICATION IN Huh-7 CELLS BY THE NS3 PROTEASE INHIBITOR SCH5030334: A STOCHASTIC MATHEMATICAL MODEL by E. L. Mishchenko, N. V. Ivanisenko, I. R. Akberdin, P. S. Demenkov, V. A. Likhoshvai, N. A. Kolchanov, V. A. Ivanisenko

“…Hepatitis C virus (HCV) causes a severe liver disease frequentlyassociatedwith cirrhosis andhepatocellular carcinoma. …”
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Latent Inflammation and Insulin Resistance in Adipose Tissue by I. S. Stafeev, A. V. Vorotnikov, E. I. Ratner, M. Y. Menshikov, Ye. V. Parfyonova

“…It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myocarditis, and hypertension. …”
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Evaluation of the role of unconventional prefoldin RPB5 interactor (URI1) in hepatitis B virus infection by Karolína Štaflová, Aleš Zábranský, Iva Pichová

“…Abstract Hepatitis B virus (HBV) infection can cause liver disease and lead to hepatocellular carcinoma (HCC). …”
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A Case of Prolonged Cholestatic Hepatitis Induced by Azithromycin in a Young Woman by Caterina Maggioli, Luca Santi, Giacomo Zaccherini, Vittoria Bevilacqua, Francesca Giunchi, Paolo Caraceni

“…We here report the case of a prolonged cholestatic hepatitis after administration of azithromycin in a young woman with no history of liver disease.…”
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Liver Protective Effect of Fenofibrate in NASH/NAFLD Animal Models by Ali Mahmoudi, Seyed Adel Moallem, Thomas P. Johnston, Amirhossein Sahebkar

“…Nonalcoholic fatty liver disease (NAFLD) is initiated by excessive fat buildup in the liver, affecting around 35% of the world population. …”
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A mutation in LXRα uncovers a role for cholesterol sensing in limiting metabolic dysfunction-associated steatohepatitis by Alexis T. Clark, Lillian Russo-Savage, Luke A. Ashton, Niki Haghshenas, Nicolas A. Amselle, Ira G. Schulman

“…Reengaging LXR signaling by treatment with synthetic agonist reverses MASH in LXRα mutant mice suggesting that LXRα normally functions to impede the development of liver disease.…”
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Bile acids and incretins as modulators of obesity-associated atherosclerosis by Andrijana Kirsch, Juergen Gindlhuber, Diana Zabini, Elena Osto, Elena Osto

“…Obesity is one of the major global health concerns of the 21st century, associated with many comorbidities such as type 2 diabetes mellitus (T2DM), metabolic dysfunction-associated steatotic liver disease, and early and aggressive atherosclerotic cardiovascular disease, which is the leading cause of death worldwide. …”
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Postinfantile Giant Cell Hepatitis with Features of Acute Severe Autoimmune Hepatitis Probably Triggered by Diclofenac in a Patient with Primary Myelofibrosis by Pinelopi Arvaniti, Kalliopi Zachou, George K. Koukoulis, George N. Dalekos

“…Giant cell hepatitis (GCH) is commonly reported in neonatal and infantile liver diseases but rarely in adults where the term postinfantile GCH (PIGCH) is used. …”
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MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR by Eduardo José Brommelstroet Ramos, Hugo Pinto Marques, Martin Palavecino, Timothy Pawlik, Rene Adam, Olivier Soubrane, Paulo Herman, Ricardo Lemos Cotta-Pereira

“…Patients with no bowel occlusion and with extensive liver disease are advised neoadjuvant oncological therapy. …”
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The Diagnosis Is in the Smear: A Case and Review of Spur Cell Anemia in Cirrhosis by Gabriella A. Raffa, Diana M. Byrnes, John J. Byrnes

“…We present the case of a 57-year-old woman with alcoholic cirrhosis who presented with symptomatic macrocytic anemia with a hemoglobin level of 7.4 g/dL and signs of decompensated liver disease. Notably, she had no signs of overt bleeding. …”
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Reference Gene and Protein Expression Levels in Two Different NAFLD Mouse Models by Layanne C. C. Araujo, Silvana Bordin, Carla R. O. Carvalho

“…The aim of this work was to evaluate reference gene and protein expression in models of nonalcoholic fatty liver disease, using mice fed with a high-fat diet (HFD) and mice that are genetically obese (ob/ob). …”
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Protective Effect of Thyme Extract on Albino Rats Exposed to Paraquat by Nazar M. Shareef Mahmood

“…Paraquat (PQ), as a frequently used compound in many applications while the  herbal providing is vigorously used in the curing of broad spectrum diseases such as liver disease, the influence of thyme extract or Thymus vulgaris L. …”
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The Laboratory Diagnosis of Hepatitis B Virus by Mel Krajden, Gail McNabb, Martin Petric

“…Without intervention, approximately 15% to 40% of chronically infected individuals will eventually develop cirrhosis, end-stage liver disease or hepatocellular carcinoma, or require liver transplantation. …”
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Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis by Livia Melo Villar, Cristianne Sousa Bezerra, Helena Medina Cruz, Moyra Machado Portilho, Geane Lopes Flores

“…Hepatitis B virus (HBV) is one of the major causes of chronic liver disease worldwide; however most of individuals are not aware about the infection. …”
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Life-Threatening Necrotizing Fasciitis of the Posterior Neck by Ji-An Choi, Jung-Ha Kwak, Chung-Min Yoon

“…Necrotizing fasciitis is an infection of the subcutaneous tissue that results in destruction of the fascia and is disproportionately common in patients with chronic liver disease or diabetes. Necrotizing fasciitis of the head and neck is rare, but has a high fatality rate. …”
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Why and How to Treat Chronic Hepatitis C by Stephanos J Hadziyannis

“…In clinical practice, the decision to treat should be individualized and tailored on the basis of several virus- and host-related factors, particularly the grade and stage of liver disease, HCV genotype and levels of viremia. Appropriate monitoring of therapy by careful clinical evaluation, liver biochemistry and serumHCVRNAtesting is mandatory. …”
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