Prevalence of GCKR rs1260326 Variant in Subjects with Obesity Associated NAFLD and T2DM: A Case-Control Study in South Punjab, Pakistan by Tayyaba Nisar, Kashan Arshad, Zahid Abbas, Maira Ali Khan, Sohail Safdar, Rehan Sadiq Shaikh, Ali Saeed

“…The glucokinase regulatory protein (GCKR) regulates glycogen metabolism and insulin secretion, and the GCKR rs1260326 is a putative single nucleotide polymorphism (SNP) associated with metabolic disorders including nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM). …”
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Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay, and Short-Term Survival after Liver Transplantation in a High MELD Population by Mark R. Pedersen, Myunghan Choi, Jeffrey A. Brink, Anil B. Seetharam

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Hepatoprotective effects of propolis ethanol extract on D-galactose-induced aging mice: A metabolomics and transcriptomics analysis focusing on insulin resistance pathways by Jinjia Liu, Songhao Tian, Jixiang Wang, Qing Sang, Wenting Su, Jinqiang Wu, Fenglei Zai

“…These findings provide a scientific foundation for the therapeutic potential of PEE in anti-aging and liver disease.…”
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Liver cirrhosis epidemiology in Chelyabinsk region in 2006-2015 by A. I. Dolgushina, Ye. R. Olevskaya, A. N. Tarasov, M. S. Kazakova, A. Yu. Markina

“…Statistically significant increase of the both total (254.1-391.8 per 100,000 population) and primary (43.3-67.3 per 100,000 population) incidence of the liver diseases was detected. For the 10-year period of monitoring considerable sporadic fluctuations due to the liver diseases were noted. …”
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Economic Evaluation of Boceprevir for the Treatment of Patients with Genotype 1 Chronic Hepatitis C Virus Infection in Hungary by Raymond Odhiambo, Jagpreet Chhatwal, Shannon Allen Ferrante, Antoine El Khoury, Elamin Elbasha

“…The lifetime incidence of severe liver disease events (DC, HCC, LT, LD) were projected to decrease by 45% and 61% in treatment-naïve and treatment-experienced patients treated with triple therapy groups in comparison with PEG-RBV treatment. …”
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Fungal Infections in Kidney Transplant Recipients: A Comprehensive Narrative Review by Maria Mazzitelli, Federico Nalesso, Alberto Enrico Maraolo, Vincenzo Scaglione, Lucrezia Furian, Annamaria Cattelan

“…Fungal colonization, diabetes mellitus, chronic liver disease, malnutrition, and pre-existing lung conditions should all be acknowledged as possible predisposing risk factors. …”
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Factors That Could Impact on Liver Fibrosis Staging by Transient Elastography by Hugo Perazzo, Valdilea G. Veloso, Beatriz Grinsztejn, Chris Hyde, Rodolfo Castro

“…Transient elastography (TE) based on liver stiffness measurement (LSM) is one of the most validated noninvasive methods for liver fibrosis staging in patients with chronic liver diseases. This method is painless, has no potential complications, is rapid (<10 min), and can be performed at the patient’s bedside. …”
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Gel Immersion Endoscopic Mucosal Resection (EMR) for Superficial Nonampullary Duodenal Epithelial Tumors May Reduce Procedure Time Compared with Underwater EMR (with Video) by Takeshi Yamashina, Masaaki Shimatani, Yu Takahashi, Masahiro Takeo, Natsuko Saito, Hironao Matsumoto, Takeshi Kasai, Masataka Kano, Kimi Sumimoto, Toshiyuki Mitsuyama, Hiroyuki Marusawa, Akiyoshi Nishio, Takafumi Yuba, Toshihito Seki, Makoto Naganuma

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Conducting genetic epidemiology research on hyperuricaemia and gout in an indigenous community in Guam - a feasibility study by Yvette C. Paulino, Frank Camacho, Tristan VC Paulino, Delores J. Lee, Lisa Linda Natividad, Elizabeth Matisoo-Smith, Tony R. Merriman, Anna L. Gosling

“…The prevalence of metabolic conditions from highest to lowest were obesity (55.6%), hyperuricaemia (36.0%), hypertension (27.8%), gout (23.0%), diabetes (14.9%), cardiovascular disease (8.4%), kidney disease (7.3%), and liver disease (3.4%). There was variation in the prevalence of metabolic conditions among the major ethnic groups in this study. …”
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Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis by Koichi Tsuneyama, Yen-Chen Chen, Makoto Fujimoto, Yoshiyuki Sasaki, Wataru Suzuki, Tsutomu Shimada, Seiichi Iizuka, Mitsunobu Nagata, Masaki Aburada, Shao-Yuan Chen

“…The effect of hyperbaric oxygen treatment (HBOT) was examined using MSG mice, which are an animal model of obesity, hyperlipidemia, diabetes, and nonalcoholic fatty liver disease. Nineteen MSG male mice were divided into HBOT treated and control groups at 12 weeks of ages. …”
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Mortality among Alaska Native Adults with Confirmed Hepatitis C Virus Infection Compared with the General Population in Alaska, 1995–2016 by Sara S. Bressler, Dana Bruden, Leisha D. Nolen, Michael G. Bruce, Lisa Towshend-Bulson, Philip Spradling, Brian J. McMahon

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Autoimmune Hepatitis with Acute Presentation: Clinical, Biochemical, and Histological Features of 126 Patients by Álvaro Urzúa, Carolina Pizarro, Abraham Gajardo, Rafael Poniachik, Claudia Pavez, Máximo Cattaneo, Javier Brahm, Laura Carreño, Jaime Poniachik

“…Autoimmune hepatitis (AIH) is a chronic liver disease with a relevant inflammatory component and an unknown etiology. …”
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Interleukin-6 related signaling pathways as the intersection between chronic diseases and sepsis by Jie Yang, Lin Yang, Yanjiao Wang, Lu Huai, Bohan Shi, Di Zhang, Wei Xu, Di Cui

“…Focused on the interactions of sepsis and IL-6 related pathways, some chronic diseases have been studied for association with sepsis, containing insulin resistance, Alcoholic liver disease (ALD), Alzheimer disease (AD), and atherosclerosis. …”
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Comparative evaluation of multimarker algorithms for early-stage HCC detection in multicenter prospective studies by Jinlin Hou, Thomas Berg, Arndt Vogel, Teerha Piratvisuth, Jörg Trojan, Enrico N. De Toni, Masatoshi Kudo, Katarina Malinowsky, Peter Findeisen, Johannes Kolja Hegel, Wenzel Schöning, Kairat Madin, Konstantin Kroeniger, Henry Lik-Yuen Chan, Ashish Sharma

“…Impact and implications: To improve the detection of early-stage hepatocellular carcinoma (HCC) from benign chronic liver disease (CLD), algorithms combining demographic characteristics and serum biomarkers, such as GAAD and GALAD, have been developed. …”
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Glycyrrhizin attenuates renal inflammation in a mouse Con A-hepatitis model via the IL-25/M2 axis by Lingyun Li, Yuanyue Zhang, Zhongyan Wang, Xiangyu Chen, Min Fang

“…Hepatorenal syndrome (HRS) is a functional acute renal impairment that occurs in severe liver disease, and we found that kidney injury also occurs in Con A-induced experimental hepatitis in mice. …”
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Advanced Glycation End-Product-Modified Heat Shock Protein 90 May Be Associated with Urinary Stones by Takanobu Takata, Shinya Inoue, Kenshiro Kunii, Togen Masauji, Junji Moriya, Yoshiharu Motoo, Katsuhito Miyazawa

“…Although lifestyle-related diseases (LSRDs) such as hyperglycemia, type 2 diabetic mellitus, non-alcoholic fatty liver disease/non-alcoholic steatohepatitis, and cardiovascular disease are risk factors for urolithiasis, the underlying mechanisms remain unclear. …”
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Risk Factors of Multidrug-Resistant Bacteria in Lower Respiratory Tract Infections: A Systematic Review and Meta-Analysis by Gang Chen, Kailiang Xu, Fangyuan Sun, Yuxia Sun, Ziyuan Kong, Bangjiang Fang

“…The meta-analysis results suggested that prior antibiotic treatment, inappropriate antibiotic therapy, chronic lung disease, chronic liver disease and cerebral disease, prior MDR and PA infection/colonization, recent hospitalization, longer hospitalization stay, endotracheal tracheostomy and mechanical ventilation, tube feeding, nursing home residence, and higher disease severity score were independent risk factors for MDR bacteria. …”
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Prediction of Liver Steatosis and Fibrosis Based on Clinical Variables Using a Large National Survey Database by Yanal Alnimer, Touleen Alnimer

“…Vibration-controlled transient elastography (VCTA) and controlled attenuation parameter (CAP) are used more frequently to diagnose liver fibrosis and steatosis among nonalcoholic fatty liver disease patients. However, limited robust data are available on the clinical variables strongly related to these disorders and who needs to be referred for screening. …”
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Treatment with Lobeglitazone Attenuates Hepatic Steatosis in Diet-Induced Obese Mice by Sorim Choung, Kyong Hye Joung, Bo Ram You, Sang Ki Park, Hyun Jin Kim, Bon Jeong Ku

“…Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance. …”
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The Burden of NAFLD and Its Characteristics in a Nationwide Population with Type 2 Diabetes by Gabriele Forlani, Carlo Giorda, Roberta Manti, Natalia Mazzella, Salvatore De Cosmo, Maria Chiara Rossi, Antonio Nicolucci, Paolo Di Bartolo, Antonio Ceriello, Pietro Guida, AMD-Annals Study Group

“…We studied the prevalence of nonalcoholic fatty liver disease (NAFLD) and its clinical correlates in a population of patients with type 2 diabetes mellitus (T2DM). …”
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