Model for hepatitis C virus transmissions by Elamin H. Elbasha

“…Hepatitis C virus (HCV) is a leading cause of chronic liver disease. Thispaper presents a deterministic model for HCV infection transmission and usesthe model to assess the potential impact of antiviral therapy. …”
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Glycogenic Hepatopathy: Resolution with Minimal Glucose Control by Abhimanyu Chandel, Brittany Scarpato, Jeanette Camacho, Miles McFarland, Shaffer Mok

“…As patients with glycogenic hepatopathy often have nonspecific complaints, diagnosis tends to be delayed and laboratory and imaging data are often indistinguishable from nonalcoholic fatty liver disease. Our patient’s diagnosis of glycogenic hepatopathy required a liver biopsy, which demonstrated the characteristic pathology. …”
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Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progression by Alena Laschtowitz, Eric L. Lindberg, Anna-Maria Liebhoff, Laura Anne Liebig, Christian Casar, Silja Steinmann, Adrien Guillot, Jun Xu, Dorothee Schwinge, Michael Trauner, Ansgar Wilhelm Lohse, Stefan Bonn, Norbert Hübner, Christoph Schramm

“…Impact and implications:: Primary sclerosing cholangitis (PSC) is an inflammatory liver disease that is characterized by multifocal inflammation of bile ducts and subsequent biliary fibrosis. …”
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Exploring the role of curcumin in mitigating oxidative stress to alleviate lipid metabolism disorders by Maojun Cheng, Maojun Cheng, Fang Ding, Fang Ding, Liyang Li, Liyang Li, Changmao Dai, Changmao Dai, Xiaolan Sun, Xiaolan Sun, Jia Xu, Jia Xu, Feier Chen, Feier Chen, Mingxiu Li, Xueping Li

“…An increasing body of research indicates that disorders of lipid metabolism can contribute to the development and progression of various diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD), diabetes mellitus, atherosclerosis, and cancer, potentially leading to poor prognoses. …”
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Prognostic factors for transplant-free survival in patients with secondary sclerosing cholangitis associated with critical illness by Christoph Schramm, Hartmut Schmidt, Christian Gerges, Alisan Kahraman, Christian M Lange, Jassin Rashidi-Alavijeh, Katharina Willuweit, Georgios Konstantis, Dorsa Ghaffar Loy Moghadam, Alexandra Frey, Nargiz Nuruzade, Moritz Passenberg

“…The C-index was 0.78 (95% CI 0.65, 0.91), surpassing the model of end-stage liver disease score’s prognostic accuracy (Concordance Index at 3 years: 66.2% vs 74.9%).Conclusion These findings provide valuable insights for establishing standard exception criteria for this rare liver disease, which could lead to improved organ allocation. …”
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Mendelian randomization studies of risk and protective factors for osteoporosis: a systematic review and meta-analysis by Wenhao Ji, Wenhao Ji, Bin Pan, Bin Pan, Xin Chen, Xin Chen, Zhaobai Lao, Zhaobai Lao, Wanlei Yang, Wanlei Yang, Yu Qian, Yu Qian

“…The combined findings from these 30 studies revealed that rheumatoid arthritis, inflammatory bowel disease, sex hormone binding globulin, depression, non-alcoholic fatty liver disease, primary biliary cholangitis and asthma are associated with increased risk of osteoporosis, while basal metabolic rate and gut microbiota (NB1n) serves as a protective factor. …”
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Interplay of PNPLA3 and HSD17B13 Variants in Modulating the Risk of Hepatocellular Carcinoma among Hepatitis C Patients by Carla De Benedittis, Mattia Bellan, Martina Crevola, Elena Boin, Matteo Nazzareno Barbaglia, Venkata Ramana Mallela, Paolo Ravanini, Elisa Ceriani, Stefano Fangazio, Pier Paolo Sainaghi, Michela Emma Burlone, Rosalba Minisini, Mario Pirisi

“…Carriage of PNPLA3 G∗ allele was associated with a trend of progressively more severe liver disease, from mild fibrosis to significant fibrosis, cirrhosis, and HCC (p=0.007). …”
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A Case of Granulomatosis with Polyangiitis in Pregnancy by Rashid Naseem Khan, Aliya Naseem, Muhammad Athar Khan, Qurat ul Ain Qurat ul Ain, Mamoona Hashim, Hafiza Laila Hashim Khan

“…A 25-year-old woman with chronic liver disease, vasculitis, protein C and S deficiency, hypothyroidism, and gestational diabetes presented at 24 weeks gestation with shortness of breath, fever, and vomiting. …”
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Seronegative autoimmune hepatitis by A. O. Buyeverov

“…According to available information one can postulate following: 1) clinical vigilance for SAH, especially at liver diseases with high biochemical activity; 2) performing liver biopsies in all cases of unclear diagnosis; 3) application of standard scoring diagnostic system at autoimmune hepatitis; 4) prescription of immunosuppressive therapy at justified suspicion for SAH (at ruling out of the other causes for liver disease). …”
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Intraoperative Cardiac Complications in Liver Transplantation: Preoperative Evaluation – A Narrative Review by Nedim Çekmen, Ahmed Uslu

“…The decisive treatment for end-stage liver disease (ESLD) is liver transplantation (LT). Perioperative management of LT is one of the most challenging issues for anesthesiologists. …”
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Gastrointestinal Bleeding Secondary to Portal Hypertensive Duodenopathy in a Patient with Decompensated Liver Cirrhosis by Rohini Krishna, Samuel O. Igbinedion, Richie Diaz, Nazneen Hussain, Moheb Boktor

“…With alcoholic cirrhosis and nonalcoholic fatty liver disease continuously on the rise in the United States, there is also a corresponding rise in portal hypertension. …”
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CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core: Canadian Guidelines for Management and Treatment of HIV/Hepatitis C Coinfection in Adults by Mark Hull, Marina Klein, Stephen Shafran, Alice Tseng, Pierre Giguère, Pierre Côté, Marc Poliquin, Curtis Cooper, on behalf of The CIHR Canadian HIV Trials Network HIV/Hepatitis C Management and Treatment Guidelines Working Group

“…HIV-HCV management is more complex due to the accelerated progression of liver disease, the timing and nature of antiretroviral and HCV therapy, mental health and addictions management, socioeconomic obstacles and drug-drug interactions between new HCV direct-acting antiviral therapies and antiretroviral regimens.…”
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Fatal Hepatic Decompensation in a Patient with Hepatitis B Cirrhosis Following Famciclovir Withdrawal by Robert P Myers, Rabindra Chaudhary, Kevin Fonseca, Samuel S Lee

“…Hepatitis B virus (HBV) infection is a major cause of chronic liver disease worldwide. Famciclovir is a nucleoside analogue with potent antiviral activity that appears promising in the management of patients with HBV infection. …”
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Pathological Features of New Animal Models for Primary Biliary Cirrhosis by Koichi Tsuneyama, Yuki Moritoki, Kentaro Kikuchi, Yasuni Nakanuma

“…Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by immune mediated biliary damage and frequent appearance of autoantibodies against mitochondrial enzymes. …”
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Selecting Candidates for Liver Transplantation: A Medical Ethics Perspective on the Microallocation of a Scarce and Rationed Resource by Eric M Yoshida

“…Following the success and acceptance of transplantation in the treatment of end-stage liver disease, there has been a progressive increase in the number of patients seeking a limited supply of donor organs. …”
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Use of Idarucizumab to Revert the Anticoagulant Effect of Dabigatran in Heart Transplant Surgery: An Institutional Experience by Álvaro Herrera-Escandón, Orlando Castaño-Cifuentes, Carlos A. Plata-Mosquera

“…Heart transplant is a surgical procedure with a high risk of perioperative bleeding in patients with a previous history of sternotomy, congestive liver disease, and/or use of oral anticoagulants. Anticoagulation is usually done with coumarin agents (warfarin, acenocoumarol), while on the waiting list, vitamin K is available allowing for partial reversal of the anticoagulant effect, although with variable INR and risk of uncontrolled bleeding. …”
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Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature by Ayane A. Rodrigues, Raíssa S. B. Andrade, Daniel F. P. Vasconcelos

“…The pathophysiology of nonalcoholic fatty liver disease (NAFLD) is related to unhealthy lifestyles that combine sedentary lifestyle, hypercaloric diets, excessive saturated fats, refined carbohydrates, and high intake of fructose as a food additive to various processed products. …”
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Predictors of Relapse to Significant Alcohol Drinking after Liver Transplantation by Zamil Karim, Pongphob Intaraprasong, Charles H Scudamore, Siegfried R Erb, John G Soos, Elsie Cheung, Polly Cooper, Andrzej K Buzckowski, Stephen W Chung, Urs P Steinbrecher, Eric M Yoshida

“…BACKGROUND: End-stage alcoholic liver disease is common, with many of these patients referred for liver transplantation (LT). …”
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Biological rhythms of the liver by Anatol Panasiuk, Mirosław Tarasewicz, Albert Chodowiec, Anna Łokić, Kacper Gan

“…Clock dysfunctions contribute to the pathogenesis of various disorders, including fatty liver disease, liver cirrhosis and different types of cancer. …”
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Granular Cell Tumour of the Bile Duct in Association with Intrahepatic Bile Duct Adenomas by F Schweiger, J Radhi, FW Coop, RW Murphy

“…The authors report the case of an asymptomatic Caucasian woman with biochemical evidence of liver disease who had a granular cell tumour of the bile duct as well as several intrahepatic bile duct adenomas.…”
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