Impact of Weight Reduction on Thyroid Function and Nonalcoholic Fatty Liver among Egyptian Adolescents with Obesity by Mona Karem Amin, Ahmed Ibrahim Ali, Hesham Elsayed

“…This may explain the emergence of nonalcoholic fatty liver as the leading cause of liver disease. Several previous studies have addressed the association between thyroid function and nonalcoholic fatty liver disease. …”
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Urinary tract infections in patients with decompensated liver cirrhosis, listed for liver transplantation by P. D. Bessonov, I. V. Borzunov, E. N. Bessonova

“…To study the urinary infection rate in patients with liver cirrhosis (LC) and indications for liver transplantation with assessment of etiologic spectrum and features of the progression of liver disease at development of this complication. Material and methods. …”
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Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning by Giovanni Marasco, Sinan Sadalla, Giulio Vara, Rita Golfieri, Davide Festi, Antonio Colecchia, Matteo Renzulli

“…Several measures can be obtained from cross-sectional imaging analysis to evaluate sarcopenia in patients affected by chronic liver disease. We aimed to review the recent advances in imaging-based sarcopenia assessment, in particular in patients with chronic liver diseases. …”
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Evaluation of Adrenal Function in Nonhospitalized Patients with Cirrhosis by Maryam Moini, Mitra Yazdani Sarvestani, Mesbah Shams, Masood Nomovi

“…Categorization of liver disease severity was done according to model for end-stage liver disease (MELD) score. …”
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Direct targeting of risk factors significantly increases the detection of liver cirrhosis in primary care: a cross-sectional diagnostic study utilising transient elastography by Guruprasad P Aithal, Indra Neil Guha, Stephen D Ryder, Emilie A Wilkes, David J Harman, Martin W James, Matthew Jelpke, Dominic S Ottey, Timothy R Card

“…Objectives To assess the feasibility of a novel diagnostic algorithm targeting patients with risk factors for chronic liver disease in a community setting.Design Prospective cross-sectional study.Setting Two primary care practices (adult patient population 10 479) in Nottingham, UK.Participants Adult patients (aged 18 years or over) fulfilling one or more selected risk factors for developing chronic liver disease: (1) hazardous alcohol use, (2) type 2 diabetes or (3) persistently elevated alanine aminotransferase (ALT) liver function enzyme with negative serology.Interventions A serial biomarker algorithm, using a simple blood-based marker (aspartate aminotransferase:ALT ratio for hazardous alcohol users, BARD score for other risk groups) and subsequently liver stiffness measurement using transient elastography (TE).Main outcome measures Diagnosis of clinically significant liver disease (defined as liver stiffness ≥8 kPa); definitive diagnosis of liver cirrhosis.Results We identified 920 patients with the defined risk factors of whom 504 patients agreed to undergo investigation. …”
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Metastatic Hepatocellular Carcinoma in a Patient with Crohn’s Disease Treated with Azathioprine and Infliximab: A Case Report and Literature Review by Kyle J. Fortinsky, Ali Alali, Khursheed Jeejeebhoy, Sandra Fischer, Morris Sherman, Scott Fung

“…The patient had no history of liver disease and a complete autoimmune and viral workup was unremarkable. …”
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An Overview of In Vitro Models of Alcohol‐Related Hepatocellular Carcinoma by Anoïsia Courtois, Sophie Gérard, Damien Esparteiro, Eric Nguyen‐Khac, Ingrid Marcq, Grégory Fouquet

“…ABSTRACT Background Chronic and excessive alcohol consumption is the leading cause of death due to chronic liver disease. Alcohol‐related liver disease (ALD) encompasses a broad spectrum of clinical and pathological features, ranging from asymptomatic and reversible pathologies to hepatocellular carcinoma (HCC), a highly prevalent and deadly liver cancer. …”
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Macro-Aspartate Aminotransferase and Its Laboratory Detection: A Case Report by Goda Aleknavičiūtė-Valienė, Linas Černiauskas, Mantas Riauka, Dalius Vitkus

“…In the case of an isolated elevation of AST activity with no clinical indications of liver disease, diagnostic work-up for macro-AST should always be considered by physicians. …”
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Chronic glomerulonephritis of the mixed type in patient with HBV-infection (<i>Clinical case</i>) by V. S. Adonyeva, A. B. Botchkarev, O. S. Saurina

“…Extrahepatic manifestations of viral hepatites frequently not only mask liver disease, but determine prognosis in many respects as well. …”
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Barriers Preventing Liver Transplantation in Canadians with HIV Infection – Perceptions of HIV Specialists by Curtis L Cooper, Joanne DeForest, John Gill, Richard Lalonde, on behalf of the Canadian HIV Trials Network (CTN) Co-Infection Core Group

“…A median 20% of the nearly 12,700 HIV patients followed at these sites had concurrent liver disease (20% caused by hepatitis C virus, 5% caused by hepatitis B virus and 5% were alcohol-related). …”
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Herbicide Widespread: The Effects of Pethoxamid on Nonalcoholic Fatty Liver Steatosis In Vitro by Anna Virginia Adriana Pirozzi, Antonietta Stellavato, Chiara Schiraldi, Mariateresa Giuliano

“…Due to similarities to glyphosate, we did look at the effect of pethoxamid on impaired liver cells HepG2, using a nonalcoholic fatty liver disease (NAFLD) cell model in vitro. Pethoxamid was cytotoxic starting at 1 ppm. …”
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A Hepatitis C Educational Needs Assessment of Canadian Healthcare Providers by Reza Naghdi, Karen Seto, Carolyn Klassen, Didi Emokpare, Brian Conway, Melissa Kelley, Eric Yoshida, Hemant A. Shah

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Management of hepatorenal syndrome and associated outcomes: a systematic review by Anahid Hamidianjahromi, Jamshid Roozbeh, Shahrokh Ezzatzadegan Jahromi, Mohamad Hossein Rezazadeh, Leila Malekmakan

“…Background Hepatorenal syndrome (HRS), a multiorgan condition of acute kidney injury, is seen in advanced liver disease. This study aims to evaluate the current treatment for HRS.Methods The authors searched PubMed, Scopus and Google Scholar literature. …”
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Serum Endocan as a Survival Predictor for Patients with Liver Cirrhosis by Nobuyuki Toshikuni, Kazuaki Ozaki, Joseph George, Mikihiro Tsutsumi

“…BACKGROUND: The relationship between endocan expression and outcome in patients with chronic liver disease is not fully understood.…”
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Efficacy and Safety of a Novel Pegylated Interferon Alpha-2a in Egyptian Patients with Genotype 4 Chronic Hepatitis C by Alaa Awad Taha, Ahmad El-Ray, Maged El-Ghannam, Bahaa Mounir

“…BACKGROUND: Hepatitis C virus (HCV) genotype 4 is a common infection in Egypt and is the leading cause of liver disease.…”
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Outcomes of Adult Liver Retransplantation: A Canadian National Database Analysis by Peter D. Yoon, Madhukar S. Patel, Carla F. Murillo Perez, Tommy Ivanics, Marco P.A.W. Claasen, Hala Muaddi, David Wallace, Bettina Hansen, Gonzalo Sapisochin

“…Results. 377 (6.5%) patients underwent liver retransplantation. Autoimmune liver disease and hepatitis C virus (HCV) were the most common underlying diagnoses. …”
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An atypical presentation of autoimmune hepatitis with delayed menarche in a Nigerian adolescent: a case report by Promise Udoka Asogwa, Bruno Basil, Winifred Njideka Adiri, Nelson Ugwu, Gideon Ekene Anigbo, Evaristus Offia, Casmir Orjioke

“…Abstract Background Autoimmune hepatitis is a chronic liver disease marked by immune-mediated inflammation, necrosis, and the potential to progress to cirrhosis if not treated. …”
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TFCP2 Genetic Polymorphism Is Associated with Predisposition to and Transplant Prognosis of Hepatocellular Carcinoma by Zhikun Liu, Feng Gao, Zhou Shao, Haiyang Xie, Lin Zhou, Xiao Xu, Shusen Zheng

“…These findings indicate that rs7959378 is associated with the risk of HCC in patient with chronic liver disease and prognosis of HCC patients after liver transplantation.…”
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Влияние курсового приема L-орнитин- L-аспартата на фиброз и стеатоз печени у больных ассоциированной с нарушениями метаболизма жировой болезнью печени (неалкогольной жировой болезн... by Е. V. Garanina

“…Hyperammonaemia develops both in cirrhosis and earlier fibrotic stages during metabolic-associated fatty liver disease (MAFLD). Besides neurotropic, ammonia exerts the hepatotoxic and profibrotic effects. …”
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Acyl-CoA Thioesterase 1 Contributes to Transition of Steatosis to Metabolic-Associated Steatohepatitis by Elisa Pasini, Cristina Baciu, Marc Angeli, Bianca Arendt, Diogo Pellegrina, Jüri Reimand, Keyur Patel, George Tomlinson, Mohammad T. Mazhab-Jafari, Lakshmi P. Kotra, Sandra Fischer, Johane P. Allard, Atul Humar, Mamatha Bhat

“…Metabolic dysfunction-associated steatohepatitis (MASH) has become the leading cause of chronic liver disease, but there has been no approved pharmacotherapy to date. …”
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