Comprehensive Hematological and molecular Characterization of hemoglobin Hekinan [α27(B8)Glu→Asp(α1), HBA1:c.84G > T] in a Large Thai cohort by Amornchai Suksusut, Jidapa Jaitheang, Manussavee Prapphal, Pranee Sutcharitchan, Ponlapat Rojnuckarin, Noppacharn Uaprasert

“…Background: Hemoglobin (Hb) Hekinan is a prevalent α-globin variant frequently missed in thalassemia screening centers using high-performance liquid chromatography (HPLC) or capillary electrophoresis. …”
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Recent advances in detection techniques for vitamin analysis: A comprehensive review by Xiangrui Li, Huan Lv, Wencan Luo, WenJia Yang, Linghong Kong, Qiujin Zhu, Lu Zeng

“…Here, we propose a comprehensive and critical evaluation of detection methods for water- and fat-soluble vitamins that have been studied over the past five years, including microbiology-, spectroscopy-, liquid chromatography–mass spectrometry-, electrochemistry-, sensor-, and immunoassay-based analysis techniques. …”
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Development of a metabolome-based respiratory infection prognostic during COVID-19 arrival by John I. Robinson, Laura R. Marks, Andrew L. Hinton, Jane A. O'Halloran, Charles W. Goss, Peter J. Mucha, Jeffrey P. Henderson

“…During arrival of the COVID-19 pandemic to the United States in 2020, we conducted a prognostic biomarker discovery and validation effort based upon metabolomic profiling with a liquid-chromatography-mass spectrometer (LC-MS) type used clinically for rapid toxicology. …”
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A novel LC-MS/MS analysis of vitamin D metabolites in mice serum and hair: impact of diet and light exposure by Muhammad K. Hakeem, Asma Al-Menhali, Sampath K. Elangovan, Iltaf Shah

“…Serum and hair samples from mice were analyzed under various experimental conditions for vitamin D and its metabolites using liquid chromatography-tandem mass spectrometry (LC-MS/MS). …”
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Metabolites induced by citrus tristeza virus and ‘Candidatus Liberibacter asiaticus’ influence the feeding behavior of Diaphorina citri: an electrical penetration graph and LC–MS/M... by Jingtian Zhang, Fengchun Xia, Yuhe Li, Yangyang Liu, Fengnian Wu, Xiaoling Deng, Meirong Xu

“…Hongjü plants: healthy, CLas-infected, CTV-infected, and CTV-CLas coinfected plants. Liquid chromatography with tandem mass spectrometry (LC–MS/MS) was applied to analyze the metabolites of the four groups of plants. …”
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Momordica Charantia Polysaccharides Attenuates MPP+-Induced Injury in Parkinson’s Disease Mice and Cell Models by Regulating TLR4/MyD88/NF-κB Pathway by Dengjun Guo, Jie Zhou, Meng Zhang, Reyisha Taximaimaiti, Xiaoping Wang, Hai Wang

“…High-performance liquid chromatography and enzyme-linked immunosorbent assay (ELISA) were used to determine neurotransmitters and metabolites, inflammatory factors TNF-α and IL-1β, oxidative stress-related markers SOD, MDA, and GSH in striatum tissues. …”
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Preparation, Purification, Identification and Anti-lipid Oxidation of Kidney Bean Skin Polyphenols by Lilan SUN, Kun WANG, Youliang ZHANG, Ruokun WANG, Feng ZUO

“…Purified the crude extraction with HPD600 macroporous resin, and analyzed the phenolic composition using liquid chromatography-mass spectrometer. Shelf life predication model of peanut oil was established with peroxide value as the indicator using the Arrhenius equation. …”
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RETRACTED: Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection by Yukihiro Hiramatsu, Takashi Nishida, Dendi Krisna Nugraha, Fuminori Sugihara, Yasuhiko Horiguchi

“…Our results also indicate that the brown pigment produced by the bacterium is melanin, because HppD is involved in the biosynthesis of a type of melanin called pyomelanin, and homogentisic acid, the monomeric precursor of pyomelanin, was detected by high-performance liquid chromatography-mass spectrometry analyses. In an infection assay using macrophages, the hppD-deficient mutant was internalized by THP-1 macrophage-like cells, similar to the wild-type strain, but was less able to survive within the cells, indicating that melanin protects B. parapertussis from intracellular killing in macrophages. …”
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Stereospecific α-glucosidase inhibition, kinetics, and molecular docking studies on isolated diastereomeric alkaloids from Uncaria longiflora by Nurul Aina Suzlin Sulaiman, Muhammad Farhan Syakir Nor Azman, Mohd Fadhlizil Fasihi Mohd Aluwi, Zainul Amiruddin Zakaria, Mohammad Jemain Mohammad Ridhwana, Fatimah Salim

“…Phytochemicals isolation was conducted using various chromatographic methods, with purification achieved through recycling high-performance liquid chromatography (rHPLC) and elucidation performed using various spectroscopic techniques. …”
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Comparative Study of Lipid Profile for Mice Treated with Cyclophosphamide by HPLC-HRMS and Bioinformatics by Ekaterina Demicheva, Fernando Jonathan Polanco Espino, Pavel Vedeneev, Vadim Shevyrin, Aleksey Buhler, Elena Mukhlynina, Olga Berdiugina, Alicia del Carmen Mondragon, Alberto Cepeda Sáez, Aroa Lopez-Santamarina, Alejandra Cardelle-Cobas, Olga Solovyova, Irina Danilova, Jose Manuel Miranda, Elena Kovaleva

“…<b>Methods:</b> In this work, we identified a set of lipid biomarkers of immunodeficiency states by performing high-performance liquid chromatography–high-resolution mass spectrometry (HPLC-HRMS) analysis of blood plasma samples from mice and processing them with bioinformatics approaches. …”
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Exploring the Potential Effectiveness of <i>Croton tiglium</i> Oil and Its Nano-Emulsion on <i>Earias insulana</i> (Lepidoptera: Nolidae) by Karima S. Khater, Marwa M. Abd-Elrhmman, Zeinab M. E. A. Said, Ali A. El-Sayed, Abdelhadi A. I. Ali, Lamya Ahmed Alkeridis, Laila A. Al-Shuraym, Jingwen Wang, Qichun Zhang, Ahmed A. A. Aioub

“…We assessed their biological effects across different developmental stages and performed histological and ultrastructural examinations. Gas–liquid chromatography (GLC) identified several bioactive compounds in <i>C. tiglium</i> oil crushed dry seeds, including fatty acids, hydrocarbons, and sterols. …”
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Pharmacokinetics and Bioequivalence of Two Fixed-Dose Combination Tablets of Valsartan/Amlodipine (80/5 Mg) in Healthy Chinese Subjects by Tian M, Huang J, Chen Y, Jin Q, Jiang H, Shi C, Mei J, Xu M, Yu X, Yang S

“…Plasma concentrations of valsartan and amlodipine were determined using ultrahigh-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS), and the noncompartmental analysis method was used for estimating the pharmacokinetic parameters.Results: Under fasting conditions, the within-subject standard deviations (Swr) of maximum plasma concentration (Cmax), area under the concentration–time curve from time 0 to the time of the last-measurable plasma concentration (AUC0−t), and area under the concentration–time curve from time 0 extrapolated to infinity (AUC0−∞) for valsartan were calculated to be ≥ 0.294 and evaluated by the reference-scaled average bioequivalence (RSABE) method. …”
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A new strategy for pharmacodynamic substance screening and research on gut microbiota pathway mechanisms based on UPLC-Q-orbitrap-MS and 16S rRNA by Zhiying Yu, Tong Li, Jie Yang, Jianghua He, Weijiang Zhang, Siyuan Li, Yunpeng Qi, Yihui Yin, Ling Dong, Wenjuan Xu

“…Ultra-performance liquid chromatography-quadrupole-orbitrap mass spectrometer was used to identify the prototype and metabolic components of GQD in the colon during UC. …”
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Microbial phenolic metabolites are associated with better frontal lobe cognition by Inés Domínguez-López, Isabella Parilli-Moser, Anna Vallverdú-Queralt, Anna Tresserra-Rimbau, Cinta Valls-Pedret, Zenaida Vázquez-Ruiz, Olga Castañer, Ramon Estruch, Emili Ros, Rosa M. Lamuela-Raventós

“…A novel method based on liquid chromatography coupled to mass spectrometry was used to identify urinary MPM (protocatechuic acid, enterodiol glucuronide, enterolactone glucuronide, urolithin B glucuronide, and vanillic acid glucuronide), and cognitive function was evaluated with neuropsychological tests. …”
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Analysis of thyroid function and structure and serum metabolomics in pregnant rats exposed to airborne contaminants: Combined perchlorate, thiocyanate, and nitrate exposure by Chenchen Wang, Xiaohui Xu, Jiangling Yuan, Ran An, Aierken Taxitiemuer, Yan Zhang, Tao Luo, Jing Zhou, Chang Wang, Ling Zhang, Shunhua Wu

“…Methods: We established a Sprague-Dawley pregnant rat model exposed to perchlorate, nitrate, and thiocyanate at different gestational stages and compared maternal serum thyroid function levels, foetal development, thyroid morphology, and pathological changes between exposed and non-exposed groups at different concentrations. We used liquid chromatography-tandem mass spectrometry metabolomics methods to investigate corresponding changes in serum metabolites and metabolic biomarkers and identify metabolism-related pathways. …”
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Induced Defense in Ryegrass–Epichloë Symbiosis Against <i>Listronotus bonariensis</i>: Impact on Peramine Levels and Pest Performance by Manuel Chacón-Fuentes, Gunnary León-Finalé, Marcelo Lizama, Gastón Gutiérrez-Gamboa, Daniel Martínez-Cisterna, Andrés Quiroz, Leonardo Bardehle

“…To evaluate peramine production and its increase in response to ASW attack, peramine levels in leaves were analyzed using liquid chromatography. Damaged E+ ryegrass plants showed significant increases in peramine, with adult and larval herbivory raising levels by 291% and 216% in stems and by 135% and 85% in leaves, respectively, compared to controls. …”
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Age but not vitamin D is related to sarcopenia in vitamin D sufficient male elderly in rural China by Weinuo Mi, Huifeng Zhang, Lina Zhang, Xingjia Li, Zhiguo Wang, Yu Sun, Tonggao Shen, Kuanlu Fan, Chao Liu, Shuhang Xu

“…Serum 25(OH)D levels were measured using the liquid chromatography with tandem mass spectrometry. Correlations of serum 25(OH)D level with sarcopenia and its components in Chinese elderly were identified by the binary logistic regression and linear regression analyses. …”
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A Novel Copolymer-Based Functional SPECT/MR Imaging Agent for Asialoglycoprotein Receptor Targeting by Pu Zhang MS, Zhide Guo MS, Deliang Zhang MS, Chang Liu MS, Guibing Chen MM, Rongqiang Zhuang PhD, Manli Song MS, Hua Wu PhD, Xianzhong Zhang PhD

“…Then the copolymer P(VLA-co-VNI-co-V 2 DTPA) ( p VLND 2 ) was synthesized and characterized by gel permeation chromatography, dynamic light scattering, and high-performance liquid chromatography analysis. After labeling with 99m Tc and Gd simultaneously, the radiochemical purity, toxicity, relaxivity (r 1 ), and in vivo SPECT/MR imaging in mice were evaluated. …”
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Rapid Screening and Quantitative Determination of Illegal Phosphodiesterase Type 5 Inhibitors (PDE-5i) in Herbal Dietary Supplements by Thi Oanh Nguyen, Cao-Son Tran, Thi Thu Hang Do, Thi Minh Hoa Nguyen, Quang-Dong Bui, Cao-Tien Bui, Hong-Ngoc Nguyen, Thu-Hien Dang, Viet-Chien Dinh, Thi Anh Huong Nguyen, Thi Hong Hao Le

“…The quality and safety of dietary supplements for enhancing male sexual performance have been questioned, raising the need for continual development of analytical methods. Liquid chromatography coupled with high-resolution mass spectrometry has become one of the most effective methods to identify and measure PDE-5i concentration. …”
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Metabolite profiling in assessing ulcerative colitis activity: A systematic review by Danyang Cui, Xu Han, Jiazhu Jin, Yanhong Wang, Zijia Chen, Yang Gong, Miao Jiang

“…Qualitative analysis was performed according to the classification of gas chromatography/mass spectrometry, liquid chromatography/mass spectrometry, or nuclear magnetic resonance. …”
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