Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur... by Lihua Huang, Liuliu He, Qingfeng Zeng, Jinjing Huang, Xiaoyan Luo, Qiuming Zhong

“…This study aimed to investigate the correlation between HbA1c levels and all-cause and cardiovascular disease (CVD) mortality in elderly individuals with non-diabetic CKD.MethodsData from the NHANES (1999-2018) were analyzed to measure HbA1c levels in whole blood using high-performance liquid chromatography (HPLC). Information on deaths and subsequent details was collected through the National Mortality Index until December 31, 2019. …”
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Effects of Simulated Circulation Temperature Changes on the Flavor of Lentinula edodes during Storage by LIU Yani, WANG Feiyu, LI Ran, GAO Hong, FAN Xiuzhi, YIN Chaomin, CHENG Shilun, YU Wei, SHI Defang

“…To investigate the effects of three circulation methods including normal temperature, cold chain, and broken cold chain on the flavor substances of fresh Lentinula edodes before and after storage and transportation, the changing trends of volatile flavor compounds and taste components of L. edodes during simulated transportation under the three temperature conditions were analyzed using an electronic nose, gas chromatography-ion mobility spectrometry (GC-IMS), an electronic tongue, high performance liquid chromatography (HPLC), and an automatic amino acid analyzer. …”
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Danggui-Shaoyao-San Can Ameliorate Alzheimer’s Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology by Zhang KX, Zhang JW, Jiang YH, Wang YR, Liu ZL, Ding PL, Wang XY, Cui WQ, Xu XQ, Wang YH

“…Kai-Xin Zhang,1 Ji-Wei Zhang,2 Yan-Hong Jiang,1 Yi-Ran Wang,1 Zhen-Ling Liu,1 Peng-Li Ding,1 Xiang-Ying Wang,1 Wen-Qiang Cui,3 Xiang-Qing Xu,3,* Ya-Han Wang3,* 1First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 2College of Acupuncture and Massage, Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 3Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiang-Qing Xu, Ya-Han Wang; Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China, Email happyxiangqing@163.com; sdwangyahan@sina.comBackground: Danggui-Shaoyao-San (DSS) is a traditional Chinese medicine prescription with a history of nearly 2000 years, originally widely used for gynecological diseases, and in recent years research has found that DSS also has a good therapeutic effect on Alzheimer’s disease (AD).Purpose: The objective is to investigate the metabolic components of the DSS in the blood and the potential mechanisms for AD.Materials and Methods: Liquid chromatography‒mass spectrometry (LC-MS) combined with gas chromatography‒mass spectrometry (GC-MS) based non-targeted metabolomics were used to conduct in-depth research. …”
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Quantitative proteomics and targeted metabolomics reveal the role of Cassia siamea L. extract in the response to high-fat diet-induced obesity in Drosophila by Ananya Dechakhamphu, Nattapong Wongchum, Theeraphan Chumroenphat, Alongklod Tanomtong, Sirithon Siriamornpun

“…Methods: CSE was obtained via extraction from C. siamea wood with 70 % ethanol and its phytochemical content was analyzed by gas chromatography–mass spectrometry (GC‒MS) and high-performance liquid chromatography (HPLC). Drosophila was used to examine the effects of supplementation with C. siamea extract on lipase activity, body weight, triglyceride levels, physical strength, survival, and antioxidant activity in Drosophila fed a high-fat diet. …”
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The effects of age and sex on reference intervals for cobalamin, homocysteine, and serum and urinary methylmalonic acid in healthy adult dogs by Anna‐Lena Proksch, Sophia Schaefer, Vanessa Dreller, Judith Langenstein, Ralph Fingerhut, Natali Bauer, Andreas Moritz

“…Cobalamin and markersB12met were determined using chemiluminescence immunoassay (cobalamin) and liquid chromatography/tandem mass spectrometry (homocysteine, sMMA, uMMA:crea). …”
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The effects of Thymus capitatus essential oil topical application on milk quality: a systems biology approach by Ralph Nehme, Chiara Gini, Elise Vanbergue, Sergine Even, Filippo Biscarini, Sonia Andrés, Lucie Rault, Faustine Noel, Valerie Hardit, Said Bouhallab, David M. Pereira, Riadh Ksouri, Philippe Roussel, Secundino López, Paola Cremonesi, Bianca Castiglioni, Donatella Caruso, Fiorenza Faré, Manuela Fontana, Fabrizio Ceciliani, Latifa Abdennebi-Najar

“…This study aimed to investigate the impact of Thymus capitatus essential oil (TCEO), known for its high antibacterial and antioxidant properties, on milk microbiota using 16S rRNA sequencing, the lipidomic profile via liquid chromatography-quadrupole time-of-flight mass spectrometry, udder skin microbiota, and inflammatory biomarkers of dairy cows at the end of lactation. …”
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Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates by Mengping Liu, Erica Cook, Yanshan Dai, Erich Ehlert, Francois du Plessis, Jacek Lubelski, Bogdan G. Sleczka, Petia Shipkova, Zhuyin Li, Joshua Gamse, David Gordon, Leonard P. Adam, Paul C. Levesque, Glen B. Banks

“…At 1 month post-dose, we compared tissue vector genomes, mRNA, and microdystrophin-FLAG protein levels by meso-scale discovery-enzyme-linked immunosorbent assay, liquid chromatography-mass spectrometry, and immunofluorescence. …”
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Vermicomposting of coir pith and cow manure: Influence of initial total phenolic content on earthworms’ performance by Kanokwan Pundee, Saengchai Akeprathumchai, Sudarut Tripetchkul

“…High performance liquid chromatography (HPLC) results showed that the total numbers of water-soluble phenolics of coir pith and cow manure were, respectively, 17 and 16 out of which 5 and 4 were unique to coir pith and cow manure, respectively. …”
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Contrasting seasonal patterns in particle aggregation and dissolved organic matter transformation in a sub-Arctic fjord by M. G. Digernes, Y. V. Bodur, M. Amargant-Arumí, O. Müller, J. A. Hawkes, S. G. Kohler, U. Dietrich, M. Reigstad, M. L. Paulsen

“…Before and after incubation, samples were collected for dissolved and particulate organic carbon concentrations (DOC, POC), extracellular polymeric substances (EPSs), microbial community (flow cytometry), and molecular composition of DOM (high-performance liquid chromatography coupled to high-resolution mass spectrometry – HPLC-HRMS). …”
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Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis by Fanxuan Zhang, Fang Wang, Lisha Zhao, Leqian Wang, Wenjing Li, Feihua Huang, Feihua Huang, Nani Wang, Nani Wang

“…Ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was applied to identify the absorbed components of YNJ.ResultsYNJ attenuated pulmonary damage in LPS-treated mice, as evidenced by reduced protein content in bronchoalveolar lavage fluid, decreased lung wet/dry weight ratio, and improved respiratory function. …”
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Isoniazid urine spectrophotometry for prediction of serum pharmacokinetics in adults with TB by P. S. Rao, K. Reed, N. Modi, D. Handler, K. Petros de Guex, S. Yu, L. Kagan, R. Reiss, N. Narayanan, C. A. Peloquin, A. Lardizabal, C. Vinnard, T. A. Thomas, Y. L. Xie, S. K. Heysell

“…Dose adjustment can be personalized by measuring peak serum concentrations; however, the process involves cold-chain preservation and laboratory techniques such as liquid chromatography (LC)/mass spectrometry (MS), which are unavailable in many high-burden settings. …”
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Identification of Adulterated Deer Blood Crystals in Traditional Chinese Medicine Based on MALDI-TOF MS Peptide Fingerprints Technique by Shen-xing WANG, Ling CAO, Qing HUANG, Cong-yu MA, Jian-bin PAN, Hao-dong ZHAO, Hai-wei SHI, Bin DI, Hong-yuan CHEN

“…Firstly, Skyline software was used to predict candidate peptides by identifying the theoretical characteristic peptides for each species, and the mass spectrometry data of the tryptic digests were collected using ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometer (UPLC-Q-TOF MS). …”
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High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report by Tsuyoshi Okura, Etsuko Ueta, Risa Nakamura, Yohei Fujioka, Keisuke Sumi, Kazuhisa Matsumoto, Kyoko Shoji, Kazuhiko Matsuzawa, Shoichiro Izawa, Yuri Nomi, Hitomi Mihara, Yuzuru Otsuka, Masahiko Kato, Shin-ichi Taniguchi, Kazuhiro Yamamoto

“…We have developed a highly sensitive liquid chromatography-tandem mass spectrometry method for measuring AGEs in human serum. …”
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Characterization of Thirty Germplasms of Millet Pepper (<i>Capsicum frutescens</i> L.) in Terms of Fruit Morphology, Capsaicinoids, and Nutritional Components by Ruihao Zhang, Mengjuan Li, Junheng Lv, Pingping Li, Yunrong Mo, Xiang Zhang, Hong Cheng, Qiaoling Deng, Min Gui, Minghua Deng

“…At the same time, high-performance liquid chromatography (HPLC) and gas chromatography (GC) were used to determine the fruit of capsaicin, dihydrocapsaicin, nordihydrocapsaicin, fatty acids, vitamin E (VE), total phenol, total sugar, and total dietary fiber. …”
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Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations by Imad Ed-Dahmani, Mohamed El Fadili, Ghizlane Nouioura, Fahd Kandsi, Yassine El Atki, Hatem A. Abuelizz, Raffaele Conte, Fatima Zahra Lafdil, Abdeslam Taleb, Abdelfattah Abdellaoui, Mustapha Taleb

“…IntroductionFerula communis has demonstrated an abundance of pharmacological and antioxidative qualities.MethodsThis study investigates the antioxidant activity of F. communis leaf aqueous extract, total polyphenol and flavonoid concentrations, and ultra-high-performance liquid chromatography (UHPLC) composition and then evaluates the toxicity of the plant’s leaves in vitro and in silico. …”
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Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro by Natalia Ardila-Chantré, Claudia Marcela Parra-Giraldo, Yerly Vargas-Casanova, Andrea Carolina Barragán-Cardenas, Ricardo Fierro-Medina, Zuly Jenny Rivera-Monroy, Jhon Erick Rivera-Monroy, Javier Eduardo García-Castañeda

“…Methods: Hybrid peptides and precursors were synthesized by solid-phase peptide synthesis using the Fmoc/tBu strategy, purified via reverse phase (RP)-solid phase extraction, and characterized by RP-high performance liquid chromatography (RP-HPLC) chromatography and mass spectrometry. …”
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Antioxidant Action and In Vivo Anti-Inflammatory and Antinociceptive Activities of Myrciaria floribunda Fruit Peels: Possible Involvement of Opioidergic System by Izabelly Bianca da Silva Santos, Bruno Santos dos Santos, João Ricardhis Saturnino de Oliveira, Wêndeo Kennedy Costa, Adrielle Zagmignan, Luís Cláudio Nascimento da Silva, Magda Rhayanny Assunção Ferreira, Vilmar Luiz Lermen, Maria Silvanete Benedito de Sousa Lermen, Alexandre Gomes da Silva, Rafael Matos Ximenes, Luiz Alberto Lira Soares, Patrícia Maria Guedes Paiva, Vera Lúcia de Menezes Lima, Maria Tereza dos Santos Correia, Márcia Vanusa da Silva

“…Finally, the chemical characterization of this extract was performed by high-performance liquid chromatography (HPLC). MfAE (extract obtained using acetone as solvent) showed the higher levels of phenols (296 mg GAE/g) and anthocyanins contents (35.65 mg Cy-3-glcE/g) that were associated with higher antioxidant activity. …”
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Exploring the metabolic dynamics, storage stability, and functional potential of Lacticaseibacillus rhamnosus Probio-M9-fermented milk by Xiaoye Liu, Kaiyang Liu, Jie Yang, Hui Qiao, Lai-Yu Kwok, Wenyi Zhang

“…Metabolite profiles were generated using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight MS with multiple segment extraction. …”
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Baccaurea ramiflora fruit peel powder supplementation prevented inflammatory cell infiltration, oxidative stress, and fibrosis in carbon tetrachloride (CCl4) administered ovariecto... by Tahsin Zahan, Mirza Alimullah, Ishrat Jahan, Md. Borhan Uddin, Khondker Ayesha Akter, Md. Junaeid Rahman, Shahnaz Siddiqua, Kamrun Nahar Ela, Sakil Amin, Khondoker Shahin Ahmed, Hemayet Hossain, Ferdous Khan, Md Ashraful Alam, Nusrat Subhan

“…Methods: High-performance liquid chromatography (HPLC) analysis was done on Baccaurea ramiflora fruit peel powder extract to confirm the presence of phenolic antioxidants. …”
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Endogenous sex hormone levels are associated with the revised Framingham Stroke Risk Profile in postmenopausal women: a longitudinal study in a Swedish cohort by Kristin Ottarsdottir, Åsa Tivesten, Claes Ohlsson, Ying Li, Margareta Hellgren, Ulf Lindblad, Bledar Daka

“…The participants were physically examined in 2002–2005 and sex hormones were analysed with liquid chromatography-tandem mass spectrometry assay (LC-MS/MS). …”
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