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821
Recent advances in detection techniques for vitamin analysis: A comprehensive review
Published 2025-02-01“…Here, we propose a comprehensive and critical evaluation of detection methods for water- and fat-soluble vitamins that have been studied over the past five years, including microbiology-, spectroscopy-, liquid chromatography–mass spectrometry-, electrochemistry-, sensor-, and immunoassay-based analysis techniques. …”
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822
A novel LC-MS/MS analysis of vitamin D metabolites in mice serum and hair: impact of diet and light exposure
Published 2025-02-01“…Serum and hair samples from mice were analyzed under various experimental conditions for vitamin D and its metabolites using liquid chromatography-tandem mass spectrometry (LC-MS/MS). …”
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823
Metabolites induced by citrus tristeza virus and ‘Candidatus Liberibacter asiaticus’ influence the feeding behavior of Diaphorina citri: an electrical penetration graph and LC–MS/M...
Published 2025-02-01“…Hongjü plants: healthy, CLas-infected, CTV-infected, and CTV-CLas coinfected plants. Liquid chromatography with tandem mass spectrometry (LC–MS/MS) was applied to analyze the metabolites of the four groups of plants. …”
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824
Momordica Charantia Polysaccharides Attenuates MPP+-Induced Injury in Parkinson’s Disease Mice and Cell Models by Regulating TLR4/MyD88/NF-κB Pathway
Published 2021-01-01“…High-performance liquid chromatography and enzyme-linked immunosorbent assay (ELISA) were used to determine neurotransmitters and metabolites, inflammatory factors TNF-α and IL-1β, oxidative stress-related markers SOD, MDA, and GSH in striatum tissues. …”
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825
RETRACTED: Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection
Published 2021-10-01“…Our results also indicate that the brown pigment produced by the bacterium is melanin, because HppD is involved in the biosynthesis of a type of melanin called pyomelanin, and homogentisic acid, the monomeric precursor of pyomelanin, was detected by high-performance liquid chromatography-mass spectrometry analyses. In an infection assay using macrophages, the hppD-deficient mutant was internalized by THP-1 macrophage-like cells, similar to the wild-type strain, but was less able to survive within the cells, indicating that melanin protects B. parapertussis from intracellular killing in macrophages. …”
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826
Stereospecific α-glucosidase inhibition, kinetics, and molecular docking studies on isolated diastereomeric alkaloids from Uncaria longiflora
Published 2025-01-01“…Phytochemicals isolation was conducted using various chromatographic methods, with purification achieved through recycling high-performance liquid chromatography (rHPLC) and elucidation performed using various spectroscopic techniques. …”
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827
Comparative Study of Lipid Profile for Mice Treated with Cyclophosphamide by HPLC-HRMS and Bioinformatics
Published 2025-01-01“…<b>Methods:</b> In this work, we identified a set of lipid biomarkers of immunodeficiency states by performing high-performance liquid chromatography–high-resolution mass spectrometry (HPLC-HRMS) analysis of blood plasma samples from mice and processing them with bioinformatics approaches. …”
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828
Exploring the Potential Effectiveness of <i>Croton tiglium</i> Oil and Its Nano-Emulsion on <i>Earias insulana</i> (Lepidoptera: Nolidae)
Published 2025-01-01“…We assessed their biological effects across different developmental stages and performed histological and ultrastructural examinations. Gas–liquid chromatography (GLC) identified several bioactive compounds in <i>C. tiglium</i> oil crushed dry seeds, including fatty acids, hydrocarbons, and sterols. …”
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829
A new strategy for pharmacodynamic substance screening and research on gut microbiota pathway mechanisms based on UPLC-Q-orbitrap-MS and 16S rRNA
Published 2025-01-01“…Ultra-performance liquid chromatography-quadrupole-orbitrap mass spectrometer was used to identify the prototype and metabolic components of GQD in the colon during UC. …”
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830
Analysis of thyroid function and structure and serum metabolomics in pregnant rats exposed to airborne contaminants: Combined perchlorate, thiocyanate, and nitrate exposure
Published 2025-01-01“…Methods: We established a Sprague-Dawley pregnant rat model exposed to perchlorate, nitrate, and thiocyanate at different gestational stages and compared maternal serum thyroid function levels, foetal development, thyroid morphology, and pathological changes between exposed and non-exposed groups at different concentrations. We used liquid chromatography-tandem mass spectrometry metabolomics methods to investigate corresponding changes in serum metabolites and metabolic biomarkers and identify metabolism-related pathways. …”
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831
Induced Defense in Ryegrass–Epichloë Symbiosis Against <i>Listronotus bonariensis</i>: Impact on Peramine Levels and Pest Performance
Published 2025-01-01“…To evaluate peramine production and its increase in response to ASW attack, peramine levels in leaves were analyzed using liquid chromatography. Damaged E+ ryegrass plants showed significant increases in peramine, with adult and larval herbivory raising levels by 291% and 216% in stems and by 135% and 85% in leaves, respectively, compared to controls. …”
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832
Rapid Screening and Quantitative Determination of Illegal Phosphodiesterase Type 5 Inhibitors (PDE-5i) in Herbal Dietary Supplements
Published 2021-01-01“…The quality and safety of dietary supplements for enhancing male sexual performance have been questioned, raising the need for continual development of analytical methods. Liquid chromatography coupled with high-resolution mass spectrometry has become one of the most effective methods to identify and measure PDE-5i concentration. …”
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833
Metabolite profiling in assessing ulcerative colitis activity: A systematic review
Published 2025-03-01“…Qualitative analysis was performed according to the classification of gas chromatography/mass spectrometry, liquid chromatography/mass spectrometry, or nuclear magnetic resonance. …”
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834
Effects of ultra-processed foods on the liver: insights from gut microbiome and metabolomics studies in rats
Published 2025-01-01“…Some serum biochemical indices, inflammatory factors, oxidative stress markers, hematoxylin–eosin (HE) staining of the liver, 16S ribosomal RNA (rRNA) and Liquid chromatography-mass spectrometry (LC–MS) of rat feces were detected.ResultsThe UPF diet-induced simple steatosis of the liver in rats without affecting the levels of IL-6, GSH, MDA, and SOD. …”
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835
A preliminary study on the reference intervals of vitamin K in some areas of Beijing with normal physical examination population
Published 2025-01-01“…Serum VK1, MK4, and MK7 were firstly measured by high-performance liquid chromatography and mass spectrometry in 434 subjects. …”
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836
Widely targeted metabolomics analysis reveals the dynamically changes in volatile metabolites during xiaoqu baijiu fermentation
Published 2025-01-01“…In this study, ultra-performance liquid chromatography–tandem mass spectrometry and gas chromatography–tandem mass spectrometry were used to analyze a widely targeted metabolome during the xiaoqu baijiu fermentation process. …”
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837
Residual Characteristics and Dietary Risk Assessment of Dinotefuran and Tolfenpyrad in Tea Processing
Published 2025-01-01“…The samples were extracted using acetonitrile containing 5% formic acid, salted out, purified by dispersed solid phase extraction, detected by ultra-high performance liquid chromatography-tandem mass spectrometry, and quantified by an external standard method. …”
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838
Freeze-Drying for the Reduction of Fruit and Vegetable Chain Losses: A Sustainable Solution to Produce Potential Health-Promoting Food Applications
Published 2025-01-01“…The total polyphenolic content (TPC) and the main phenolics were studied using high-performance liquid chromatography (HPLC) with a diode array detector (DAD). …”
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839
Extraction, Chemical Composition and Antidiabetic Potential of Crude Polysaccharides from Centella asiatica (L.) Urban
Published 2024-05-01“…Monosaccharide composition analysis via high-performance liquid chromatography (HPLC) demonstrated enrichment of galacturonic acid, galactose, and arabinose in P50 and P70. …”
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840
Screening Southeast Asian medicinal plants: Clausena lansium, Leea indica, Strobilanthes crispa, Vitex trifolia for anti-platelet aggregation and blood coagulation effects
Published 2025-02-01“…All extracts prolonged PT and aPTT, with Leea indica and Strobilanthes crispa being most potent. Liquid chromatography and time of flight mass spectrometry (LC-ToF-MS) analysis of Leea indica revealed gallic acid, methyl gallate, epigallocatechin, epigallocatechin-3-O-gallate, and other polyphenolic compounds. …”
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