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741
Development of the algal pigment-based salinity transfer function for lakes on the Tibetan Plateau and evaluation of the quantitative reconstruction
Published 2025-01-01“…Here, the relationship between water environmental variables and surface sediment pigment assemblage identified by high-performance liquid chromatography (HPLC) covering 95 Tibetan lake sampling sites was investigated based on multivariate statistical analysis. …”
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742
Antioxidant Vitamins as Oxidative Stress Markers in Rat Plasma After Physical Exercise - a Short Report
Published 2014-12-01“…Vitamins in rat plasma were assessed by the high-performance liquid chromatography (HPLC). Results suggest that vitamin E and C supplemented simultaneously may provide some benefit during physical exercise. …”
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743
The concentration of selected organophosphorus pesticides associated with PM10 in agricultural ambient air in Iran: Health risk assessment using Monte Carlo simulation
Published 2025-01-01“…Active sampling was conducted using a SKC pump with a selective air inlet, and the samples were analyzed via liquid chromatography-mass spectrometry. The results indicated that Diazinon exhibited the highest average concentration among PM10-bound organophosphate pesticides, measuring 4.23 ng/m³ in suburban areas and 2.51 ng/m³ in urban environments. …”
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744
Betaxanthin Profiling in Beta vulgaris Leaves and Gymnocalycium mihanovichii Grafted Cacti: A Comprehensive Study
Published 2023-12-01“…This study was focused on the identification and quantification of betaxanthins using high-performance liquid chromatography with a diode array detector coupled to electrospray ionisation mass spectrometry (HPLC-DAD-ESI-MS) in leaves of various cultivars of Beta vulgaris (beet) and Gymnocalycium mihanovichi i grafted cacti. …”
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745
Antibiotic exposure is associated with minimal gut microbiome perturbations in healthy term infants
Published 2025-01-01“…Here, we use a prospective longitudinal birth cohort of n = 323 healthy term African American children to determine the association between antibiotic exposure and the gut microbiome through shotgun metagenomics sequencing as well as bile acid profiles through liquid chromatography-mass spectrometry. Results Stool samples were collected at ages 4, 12, and 24 months for antibiotic-exposed (n = 170) and unexposed (n = 153) participants. …”
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746
The impact of weather conditions in different years on the biochemical composition of linseed oil
Published 2021-10-01“…The content of 15 fatty acids (lauric, myristic, palmitic, palmitoleic, margaric, stearic, oleic, cis-vaccenic, linoleic, linolenic, arachidic, eicosenic, arachido nic, behenic, and lignoceric) was assessed in linseed oil using gas–liquid chromatography.Results. The tested material presented a wide diversity of genes controlling different steps of fatty acids biosynthesis and genetic mechanisms involved in the responses to the changing environment. …”
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747
Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of t...
Published 2019-01-01“…While a diagnosis of polycystic ovary syndrome (PCOS) with its associated metabolic disturbances was initially considered, serum total testosterone, androstenedione, and 17-hydroxyprogesterone (17-OHP) measured by liquid chromatography tandem mass spectrometry (LC-MS/MS) were significantly increased. …”
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748
Simultaneous Quantification of 25-Hydroxyvitamin D3 and 24,25-Dihydroxyvitamin D3 in Rats Shows Strong Correlations between Serum and Brain Tissue Levels
Published 2015-01-01“…Therefore, we developed a novel analysis method by using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) to simultaneously quantify the concentrations of 25-hydroxyvitamin D3 (25(OH)D3) and 24,25-dihydroxyvitamin D3 (24,25(OH)2D3) in the serum and brain of rats fed with different dose of vitamin D3. …”
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749
Cerebellar lipid dysregulation in SCA3: A comparative study in patients and mice
Published 2025-03-01“…However, the major constituent of white matter – lipids – remains understudied in SCA3.In this study, we conducted the first unbiased investigation of brain lipids in SCA3, focusing on the disease-vulnerable cerebellum of SCA3 postmortem patients and mouse models. Liquid chromatography-mass spectrometry uncovered widespread lipid reductions in patients with SCA3. …”
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750
Pharmacokinetics of Transdermal Flunixin Meglumine Following a Single Dose in Marine Toads (Rhinella marina)
Published 2020-01-01“…Plasma was analyzed by ultra-performance liquid chromatography-tandem mass spectrometry. Samples were analyzed individually and reported as a mean of the samples at each timepoint. …”
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751
Altered O-Glycans in stimulated whole saliva from patients with primary Sjögren’s syndrome and non-pSS sicca
Published 2024-11-01“…O-linked oligosaccharides from stimulated whole saliva (SWS) samples from 24 patients with pSS, 38 patients with non-pSS sicca, and 23 healthy controls were analyzed using liquid chromatography mass spectrometer (LC-MS). Non-fractionated reduced and alkylated saliva was dot-blotted to PVDF-membrane and O-linked oligosaccharides were released using reductive beta-elimination. …”
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752
Plasma and Milk Pharmacokinetics and Estimated Milk Withdrawal Time of Tolfenamic Acid in Lactating Sheep
Published 2024-11-01“…The concentrations of tolfenamic acid in the plasma and milk were determined using high‐pressure liquid chromatography and evaluated using non‐compartmental analysis. …”
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753
Fat Body Metabolome Revealed Glutamine Metabolism Pathway Involved in Prepupal <i>Apis mellifera</i> Responding to Cold Stress
Published 2025-01-01“…In this study, the ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS)-based non-target metabolome was analyzed between the cold-treated (CT, 20 °C, 36 h) and control (CK, 35 °C) fat body in prepupal honeybees. …”
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754
High-Performance Liquid Chromatographic Ultraviolet Determination of Memantine Hydrochloride after In Vitro Transdermal Diffusion Studies
Published 2013-01-01“…The purpose of the present work was to validate an accurate and precise high-performance liquid chromatography (HPLC) method involving ultraviolet detection for the quantitative analysis of memantine hydrochloride. …”
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755
Development and comprehensive greenness assessment of HPLC method for quality control of β-sitosterol in pharmaceutical ointments with trio-color coded evaluation
Published 2025-01-01“…Abstract A simple, rapid, and reproducible high-performance liquid chromatography (HPLC) method has been developed and validated for the determination of β-sitosterol in the pharmaceutical dosage form of moist exposed burn ointment (MEBO). …”
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756
Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy
Published 2025-01-01“…Methods: We generated a mouse model of SCM induced by lipopolysaccharide (LPS) and then obtained comprehensive metabolic and genetic data from SCM mouse hearts using ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) and RNA sequencing (RNA-seq). …”
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757
Comprehensive characterization of higher order structure changes in methionine oxidized monoclonal antibodies via NMR chemometric analysis and biophysical approaches
Published 2024-12-01“…We used a forced degradation method involving concentration-dependent oxidation by peracetic acid, in which Met oxidation is site-specifically quantified by liquid chromatography-mass spectrometry. Conventional biophysical techniques report nuanced results, in which CD detects no change to the secondary structure and little change in the tertiary structure. …”
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758
Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity
Published 2018-09-01“…Metabolomics profiling was performed from plasma samples using liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. …”
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759
Investigation of 4-Nitro-N, N-diphenylaniline as a chemical tracer under high pressure high temperature reservoir conditions for enhanced oil recovery applications
Published 2025-02-01“…Ultraviolet (UV) and high-performance liquid chromatography (HPLC) techniques were established to measure the ppm-level concentrations of 4-FBA and N-TPA in the standard brine solutions. …”
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760
Residual TPO Content of Photopolymerized Additively Manufactured Dental Occlusal Splint Materials
Published 2024-12-01“…TPO extraction was conducted using a maximum of eight extraction cycles of 72 h at a temperature of 37 °C until no more TPO eluates were detected by high-performance liquid chromatography (HPLC). The margin of safety (MoS) was calculated as the ratio between the Derived No-Effect Level (DNEL) and the estimated exposure based on the amount of TPO extracted. …”
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