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621
Evaluating Methods for Aflatoxin B1 Monitoring in Selected Food Crops Within Decentralized Agricultural Systems
Published 2025-01-01“…The objectives of this study were: (1) to evaluate common AFB1 detection methods, including enzyme-linked immunosorbent assays (ELISA) and lateral-flow assays (LFA), validated via high-performance liquid chromatography (HPLC), focusing on their suitability for possible applications in decentralized, low-resource settings; and (2) to conduct a barriers-to-use assessment for commonly available AFB1 detection methods and their applicability in low-resource settings. …”
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622
Systematic and Empirical Study of the Dependence of Polyphenol Recovery from Apricot Pomace on Temperature and Solvent Concentration Levels
Published 2018-01-01“…High-performance liquid chromatography (HPLC) analysis showed that polyphenols were influenced by the selectivity of the solvent as well as the properties of each phenolic compound. …”
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623
Inhibitory Effect of Flavonoid Extract of Lotus Leaf on Alcohol-Induced Gastric Injury by Antioxidant Capacity in Mice
Published 2020-01-01“…Five compounds, including kaempferitrin, hyperoside, astragalin, phloridzin, and quercetin, were detected in FELL using high-performance liquid chromatography. Thus, FELL has an inhibitory effect on experimental alcohol-induced gastric injury because of the antioxidant capacity of the five compounds. …”
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624
Urinary Proteomic Shifts over Time and Their Associations with eGFR Decline in Chronic Kidney Disease
Published 2025-01-01“…This follow-up study investigated urinary proteomics and clinical outcomes in 18 CKD patients (stages 1–3) and 15 healthy controls using liquid chromatography–mass spectrometry and Mascot-SwissProt for protein identification. …”
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625
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis
Published 2025-02-01“…Metabolites were analyzed and identified using ultra high liquid chromatography coupled with Q Orbitrap mass spectrometry (UPLC-HRMS), followed by verification through a self-built database. …”
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626
Phenols from Vaccinium dunalianum Wight: Secondary Mass Spectrometry Fragmentation and Neuroprotective Effect
Published 2024-12-01“…In order to elucidate the health efficacy of Vaccinium dunalianum buds as a tea substitute and to reveal the material basis for its functionality, we studied the chemical constituents of V. dunalianum buds by using separation materials such as silica gel, MICHP-20p gel, Sephadex LH-20, and RP-18 combined with preparative and semi-preparative high performance liquid chromatography (HPLC), high-resolution mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. …”
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627
Comparative Oil Composition Study of the Endemic Moroccan Olive (Olea europaea subsp. maroccana) and Wild Olive (var. Sylvestris) in Central West Morocco
Published 2021-01-01“…Additionally, the tocopherol content was determined using high-performance liquid chromatography. The total amount of unsaturated fatty acids was higher in maroccana (85.24%) than that in oleasters (79.05%). …”
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628
The metabolomic approach to the comparative analysis of wild and cultivated species of oats (Avena L.)
Published 2016-12-01“…Metabolomic analysis employed gas liquid chromatography-mass spectrometry (GLC- MS) using an Agilent 6850 chromatographer (USA). …”
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629
The prevalence of thiamine deficiency among elderly nursing home residents: A cross‐sectional study
Published 2023-05-01“…Blood thiamine concentrations were measured using a high‐performance liquid chromatography method, with TD defined as a concentration of <21.3 ng/mL. …”
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630
Serum hydroxycotinine was associated with chronic kidney disease (CKD): a cross-sectional study based on NHANES
Published 2024-12-01“…Serum hydroxycotinine was measured by an isotope-dilution high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometric (ID HPLC-APCI MS/MS) method with a lower limit of detections (LLOD) at 0.015 ng/mL. …”
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631
Comprehensive Mass Spectrometric Analysis of Snake Fruit: Salak (Salacca zalacca)
Published 2021-01-01“…Ultrahigh performance liquid chromatography coupled to a Q-Orbitrap tandem mass spectrometer was able to detect 19 phenolic compounds in the salak pulp, including 5 flavanols, 6 phenolic acids, 2 flavonols, 1 flavone, and also 5 presumably new phenolic compounds. …”
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632
Development and Validation of a LC/MS/MS Method for the Determination of Duloxetine in Human Plasma and Its Application to Pharmacokinetic Study
Published 2012-01-01“…A selective, high sensitive and high throughput liquid chromatography-tandem mass spectrometry (LC-ESI-MS/MS) method has been developed and validated for the chromatographic separation and quantitation of duloxetine in human EDTA plasma using fluoxetine (IS) as an internal standard. …”
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633
Development and Validation of an RP-HPLC Method for the Quantitative Analysis of Triclosan in Human Urine
Published 2023-01-01“…In this study, a highly sensitive, fast, and cost-effective isocratic reversed-phase high-performance liquid chromatography (RP-HPLC) method coupled with solid-phase extraction for analysis of triclosan in human urine samples was developed. …”
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634
Increased DNA Dicarbonyl Glycation and Oxidation Markers in Patients with Type 2 Diabetes and Link to Diabetic Nephropathy
Published 2015-01-01“…DNA oxidation and glycation adducts were analysed in plasma and urine by stable isotopic dilution analysis liquid chromatography-tandem mass spectrometry. DNA markers analysed were as follows: the oxidation adduct 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-OxodG) and glycation adducts of glyoxal and methylglyoxal—imidazopurinones GdG, MGdG, and N2-(1,R/S-carboxyethyl)deoxyguanosine (CEdG). …”
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635
Effects of the Salt-Processing Method on the Pharmacokinetics and Tissue Distribution of Orally Administered Morinda officinalis How. Extract
Published 2020-01-01“…To clarify the pharmacokinetics and tissue distribution of these three compounds, we employed liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) to determine the contents of the three components in rat plasma and tissues. …”
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636
Combined metabolomics and 16S rDNA sequence analyses of the gut microbiome reveal the action mechanism of Fructus Akebiae against hepatic fibrosis
Published 2025-02-01“…The gut microbiota was analyzed through 16S rDNA sequencing analysis of liver metabolites using liquid chromatography-mass spectrometry. Furthermore, network pharmacology was used to determine the specific molecular regulation mechanism of FAE in hepatic fibrosis treatment.ResultsFAE treatment markedly improved the pathological changes in the hepatic fibrosis. …”
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637
Exercise on Striatal Dopamine Level and Anxiety-Like Behavior in Male Rats after 2-VO Cerebral Ischemia
Published 2022-01-01“…In vivo microdialysis was used in conjunction with high performance liquid chromatography (HPLC) and electrochemical detection to ascertain the level of dopamine in the striatum. …”
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638
Lysine Reacts with Cholesterol Hydroperoxide to Form Secosterol Aldehydes and Lysine-Secosterol Aldehyde Adducts
Published 2020-01-01“…Here, we subjected cholesterol to photosensitized oxidation, which predominantly produces Ch-5α-OOH and minor amounts of the 6α- and 6β-hydroperoxides, exposed the hydroperoxide mixture to lysine in the presence of the antioxidant 2,6-ditertiary-butyl-4-hydroxytoluene (BHT), and analysed the reaction mixture by liquid chromatography-electrospray ionization-mass spectrometry. …”
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639
Quantitative Analysis of the Multicomponent and Spectrum–Effect Correlation of the Antispasmodic Activity of Shaoyao-Gancao Decoction
Published 2022-01-01“…In this study, high-performance liquid chromatography (HPLC) was used to establish the fingerprint and determine the multiple components of SGD. …”
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640
Prednisolone pharmacokinetics in dogs with protein‐losing enteropathy
Published 2025-01-01“…Total and non‐protein bound serum prednisolone concentrations were determined using liquid chromatography tandem‐mass spectrometry, and pharmacokinetics variables were derived from the drug concentration data. …”
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