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281
Retinal and Corneal Toxicity and Pharmacokinetic Analysis of Intraocular Injection of Ganciclovir in Rabbit Eyes
Published 2019-01-01“…Aqueous GCV concentration was detected by high-performance liquid chromatography. Potential toxicity was assessed by slit-lamp examination, optical coherence tomography, fundus examination, confocal microscopy, and histology. …”
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282
Prevalence of Pharmaceuticals in Surface Water Samples in Ghana
Published 2021-01-01“…Samples were concentrated via solid-phase extraction (SPE) while liquid chromatography was used to identify and quantify the analytes. …”
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283
HPLC Quantification of Cytotoxic Compounds from Aspergillus niger
Published 2017-01-01“…A high-performance liquid chromatography method was developed and validated for the quantification of the cytotoxic compounds produced by a marine strain of Aspergillus niger. …”
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284
Profile of Secondary Metabolite Compounds in Soybean (Glycine max L.) Leaves under Different Shading Treatments
Published 2025-01-01“…The research was conducted as follows: (i) planting several soybean varieties under different shading intensities; (ii) extracting metabolic substances from soybean leaves through maceration; (iii) identifying the extracted substances using High-Performance Liquid Chromatography (HPLC); and (iv) analyzing changes in primary metabolic substances. …”
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285
Protocol for generating protein profiles and distance-based network analysis of murine tissue slices
Published 2025-03-01“…We describe steps for preparing muscle sections and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses to generate spatial protein profiles along the longitudinal skeletal muscle axis. …”
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286
Development of the High Sensitivity and Selectivity Method for the Determination of Histamine in Fish and Fish Sauce from Vietnam by UPLC-MS/MS
Published 2020-01-01“…A selective, sensitive, and rapid method by using ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for the determination of histamine in fish and fish sauce was developed. …”
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287
Forced degradation of tacrolimus and the development of a UHPLC method for impurities determination
Published 2019-09-01“…An ultra-high performance liquid chromatography method for simultaneous determination of tacrolimus impurities in pharmaceutical dosage forms has been developed. …”
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288
Long-Term Stability of Hydromorphone in Human Plasma Frozen at −20°C for Three Years Quantified by LC-MS/MS
Published 2022-01-01“…Hydromorphone concentrations were determined by ultra-performance liquid chromatography (UPLC) with gradient elution, followed by tandem mass spectrometry with electrospray ionization. …”
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289
EFFECT OF REPRODUCTIVE STAGES ON SOME BLOOD METABOLITES IN THE SHOW AND RACEHORSE MARES IN IRAQ
Published 2025-01-01“…Blood samples were collected twice via jugular venipuncture, and blood biochemical metabolic biomarkers were evaluated by gas chromatography (GC) and high liquid chromatography (HPLC). A significant (P≤0.05) increase was observed for the concentration of serum glucose and creatine of pregnant show horse mares in the last month compared to the remaining stages. …”
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290
Rapid Separation of All Four Tocopherol Homologues in Selected Fruit Seeds via Supercritical Fluid Chromatography Using a Solid-Core C18 Column
Published 2019-01-01“…Tocopherol separations employing the same Kinetex™ C18 column via supercritical fluid chromatography (SFC) and reversed-phase liquid chromatography (RP-LC) were compared. The application of the SFC system with UV diode array detection (DAD) resulted in rapid separation of all four tocopherol homologues with a total analysis time below 2 min. …”
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291
Determination of Mycotoxin Contamination Levels in Rice and Dietary Exposure Assessment
Published 2022-01-01“…A total of 23 samples were extracted using immunoaffinity columns and analyzed by high-performance liquid chromatography (HPLC) with a fluorescence detector (FLD) and post-column photochemical derivatization. …”
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292
Determination of Progestin Residues in Fish by UPLC-Q-TOF/MS Coupled with QuEChERS
Published 2019-01-01“…A novel method was developed for simultaneous determination of 10 progestin residues in fish by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF/MS) combined with a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. …”
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293
Simplex lattice design for optimization of the mass ratio of Curcuma longa L., Curcuma zedoaria (Christm.) Roscoe and Curcuma aromatica Salisb. to maximize curcuminoids content and...
Published 2021-09-01“…The individual curcuminoids (curcumin, demethoxycurcumin and bis-demethoxycurcumin) and total curcuminoid content were determined using high-performance liquid chromatography. Curcuma longa alone provided the highest content of bis-demethoxycurcumin and demethoxycurcumin. …”
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294
New and Advanced Methods in Detection of Fruit Juice Adulteration: Focusing on Nano-Biosensor
Published 2024-01-01“…Chromatographic techniques, such as high-performance liquid chromatography (HPLC) and gas chromatography (GC), are commonly used to determine the purity of fruit juices. …”
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295
Spray-Dried Microencapsulation of Oregano (Lippia graveolens) Polyphenols with Maltodextrin Enhances Their Stability during In Vitro Digestion
Published 2022-01-01“…The analyzed physical properties were morphology measured by electron microscopy and humidity; other properties evaluated were the content of total phenolic compounds, antioxidant capacity determined by DPPH and ABTS assays, and phenolic profile by ultraperformance liquid chromatography coupled to mass spectrometry (UPLC-MS). …”
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296
Application of HPLC with ELSD Detection for the Assessment of Azelaic Acid Impurities in Liposomal Formulation
Published 2013-01-01“…In the course of research and development of a new pharmaceutical formulation of azelaic acid in the liposomal form, we developed a rapid and accurate method for the detection of impurities using high-performance liquid chromatography. A chromatographic column from Merck (Purospher Star RP C18, 250–4 mm (5 μm) was used in the assay, and the mobile phase gradient consisted of three phases: A—methanol : water (5 : 95) + 1.5% (v/v) acetic acid; B—water : methanol (5 : 95) + 1.5% (v/v) acetic acid; and C—chloroform. …”
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297
Determination of 20 Neonicotinoid Insecticides and Their Metabolites in Infant Foods by a Modified QuEChERS Method Combined with HPLC-MS/MS
Published 2022-01-01“…A rapid, effective, and reliable method for the simultaneous detection of 20 neonicotinoids and their metabolites in infant foods has been developed using liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). …”
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298
Profiling Rosmarinic Acid and Sinensetin Content of Orthosiphon aristatus. from Three Different Locations with Variety Ethanol Concentration
Published 2024-08-01“…In order to determine the levels of rosmarinic acid and sinensetin in O. aristatus as well as the correlation between the two compounds, this study used high-performance liquid chromatography (HPLC) with a UV detector to analyze O. aristatus extract from three distinct locations with four different ethanol concentrations (96%, 75%, 50%, and 25%). …”
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299
Aerobic Biodegradation of Four Groups of Steroid Hormones in Activated Sludge
Published 2020-01-01“…An analytical method was developed for simultaneously monitoring four estrogens, seven androgens, seven progestogens, and eleven glucocorticoids in a single water sample using liquid chromatography-electrospray tandem mass spectrometry. …”
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300
Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557)
Published 2016-01-01“…Homogeneity testing and stability study of chloramphenicol in methanol were examined by using high performance liquid chromatography. Additionally, the uncertainties originating from the process of CRM development were comprehensively evaluated. …”
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