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1961
Role of PPARs in Trypanosoma cruzi Infection: Implications for Chagas Disease Therapy
Published 2012-01-01“…The nuclear receptors known as peroxisome proliferator-activated receptors (PPARs) have emerged as key regulators of lipid metabolism and inflammation. The precise role of PPAR ligands in T. cruzi infection or in Chagas disease is poorly understood. …”
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1962
Research Progress on Structural Identification and Biological Activity of Chinese Jujube Polysaccharides
Published 2024-12-01“…As one of the major active ingredients in Chinese jujube, polysaccharides have various functions including immunoregulatory, hepatoprotective, anemia-relieving, lipid-lowering, anti-obesity and gut microbiota regulatory effects. …”
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1963
Effect of Cornelian Cherry (Cornus mas L.) Juice on Selected Quality Properties of Beef Burgers
Published 2018-01-01“…In contrast, the CCJ was highly effective in retarding lipid oxidation in beef burgers during storage wherein even a dose of 0.5 g CCJ resulted in beneficial inhibition of oxidative changes and at the same time had no negative effect on the sensory characteristics of beef burgers. …”
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1964
The Problem of Abnormal Body Weight and Dyslipidemia as Risk Factors for Cardiovascular Diseases in Children and Adolescents with Type 1 Diabetes
Published 2021-01-01“…These patients are often overweight and obese, and the percentage of lipid disorders is particularly high. The discussed markers of CVD risk in type 1 diabetes include apolipoproteins (apo-B and apo-C3), modified forms of LDL, and the role of high-density lipoprotein (HDL). …”
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1965
Effect of Rosa Mosqueta Husk Extract (Rosa rubiginosa) on Thermooxidation of Grape Seed Oil
Published 2019-01-01“…There is a growing interest in lipid behavior with nutritional contribution. In this sense, it is necessary to determine the behavior of the grape seed oil during a thermooxidation process at 180°C. …”
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1966
Seaweed nutraceuticals and their therapeutic role in disease prevention
Published 2019-09-01“…Keywords: Functional ingredients, Glucose metabolism, Lipid metabolism, Macroalgae, Bioavailability…”
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1967
Interleukin-1β Expression Is Required for Lysophosphatidic Acid-Induced Lymphangiogenesis in Human Umbilical Vein Endothelial Cells
Published 2011-01-01“…Lysophosphatidic acid (LPA) is a lipid mediator which binds to G-protein-coupled receptors and regulates various cellular responses, including inflammation of endothelial cells. …”
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1968
Research Progress on the Biosynthesis and Applications of Functional Bile Acids
Published 2025-01-01“…Bile acid (BA), as an important amphoteric sterol in bile, can regulate glucose and lipid metabolism and homeostasis, intestinal microecology, the intestinal barrier, inflammation, the immune system and the nervous system and other physiological functions through interaction with receptors and the intestinal flora, and consequently affect metabolism and nutritional health in the body. …”
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1969
Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis
Published 2011-01-01“…In contrast, the serum lipid level did not show significant changes between the two groups. …”
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1970
Isoliquiritigenin Inhibits Atherosclerosis by Blocking TRPC5 Channel Expression
Published 2020-01-01“…We found that in ApoE−/− mice ISL could attenuate atherosclerotic lesion, reduce serum lipid levels, and inhibit TRPC5 expression. In vitro, ISL inhibited Ang II-stimulated proliferation of VSMCs and suppressed Ang II-induced TRPC5 and PCNA expressions in a dose-dependent fashion. …”
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1971
Dietary protein requirement of Chinese hook snout carp (Opsariichthys bidens) and transcriptomic analysis of the liver in response to different protein diets
Published 2025-03-01“…In contrast, the P35 group presented lower amino acid and lipid metabolism (e.g., stearoyl-CoA desaturase, glutamine synthetase, and bile salt-activated lipase) expression levels. …”
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1972
Incorporation of reduced glutathione to the extender improves frozen-thawed sperm function and fertility potential in mandarin fish (Siniperca chuatsi)
Published 2025-03-01“…Sperm motion parameters, viability, mitochondrial activity, lipid peroxidation, and apoptosis were assessed after thawing. …”
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1973
Early Subclinical Atherosclerosis in Gestational Diabetes: The Predictive Role of Routine Biomarkers and Nutrigenetic Variants
Published 2018-01-01“…We aimed to assess the predictive role of 3rd trimester lipid profile during pregnancy for the susceptibility to markers of subclinical atherosclerosis (CVD susceptibility) at 3 years in a cohort of women with history of GDM. …”
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1974
Genome-wide identification of the Sec14 gene family and the response to salt and drought stress in soybean (Glycine max)
Published 2025-01-01“…Abstract Background The Sec14 domain is an ancient lipid-binding domain that evolved from yeast Sec14p and performs complex lipid-mediated regulatory functions in subcellular organelles and intracellular traffic. …”
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1975
Antifungal activity and mechanism of Phoebe bournei wood essential oil against two dermatophytes
Published 2025-02-01“…Cellular malondialdehyde (MDA) content was positively correlated with the concentration of PWEO, suggesting that lipid peroxidation of dermatophytes was caused by PWEO. …”
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1976
IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3
Published 2025-02-01“…Knockdown of tripartite motif-containing 22 (TRIM22) suppressed the levels of intracellular Fe2+ and lipid ROS. It also reduced heme oxygenase (HMOX1) protein levels and increased ferroptosis suppressor protein 1 (FSP1) levels in HT1080 cells treated with IFNβ. …”
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1977
Pengaruh Pemberian Aspartam terhadap Kadar Low-Density Lipoprotein dan High-Density Lipoprotein pada Tikus Wistar Diabetes Melitus Diinduksi Aloksan
Published 2014-09-01“…Aspartam dapat mempengaruhi metabolisme profil lipid. Tujuan dari penelitian ini adalah mengetahui pengaruh pemberian aspartam terhadap kadar LDL dan HDL tikus diabetes melitus diinduksi aloksan. …”
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1978
Apolipoprotein A-V Is a Novel Diagnostic and Prognostic Predictor in Pediatric Patients with Sepsis: A Prospective Pilot Study in PICU
Published 2020-01-01“…Sepsis induces the release of lipid mediators, which control both lipid metabolism and inflammation. …”
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1979
Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systematic network me...
Published 2025-02-01“…Regarding the efficacy of lipid reduction, four principal medications were evaluated: evolocumab and atorvastatin [mean standard deviation (MD) −3.41, 95% CI −4.81 to −2.00] and evolocumab with rosuvastatin (MD −3.44, 95% CI −5.10 to −1.78) vs. placebo; alirocumab combined with rosuvastatin (MD −2.91, 95% CI −3.95 to −1.88) and alirocumab with atorvastatin (MD −2.90, 95% CI −3.97 to −1.84) vs. placebo. …”
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1980
O-GlcNAcylation attenuates ischemia-reperfusion-induced pulmonary epithelial cell ferroptosis via the Nrf2/G6PDH pathway
Published 2025-02-01“…Thus, we generated Ogt1-conditional knockout mice and found that Ogt1 deficiency aggravated ferroptosis, as evidenced by lipid reactive oxygen species (lipid ROS), malondialdehyde (MDA), Fe2+, as well as alterations in critical protein expression glutathione peroxidase 4 (GPX4) and solute carrier family 7 member 11 (SLC7A11). …”
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