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  1. 1901

    Endoplasmic Reticulum Is at the Crossroads of Autophagy, Inflammation, and Apoptosis Signaling Pathways and Participates in the Pathogenesis of Diabetes Mellitus by Jing Su, Lei Zhou, Xiaoxia Kong, Xiaochun Yang, Xiyan Xiang, Yu Zhang, Xiaoning Li, Liankun Sun

    Published 2013-01-01
    “…The endoplasmic reticulum (ER) is a central component of cellular functions and is involved in protein folding and trafficking, lipid synthesis, and maintenance of calcium homeostasis. …”
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    Article
  2. 1902

    Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk? by Ahmad Aljada, Kshitij Ashwin Shah, Shaker A. Mousa

    Published 2009-01-01
    “…Thiazolidinediones (TZDs) are predominantly PPARγ agonists, and their primary benefit appears to be the prevention of diabetic complications by improving glycemic control and lipid profile. Recently, the cardiovascular safety of rosiglitazone was brought to center stage following meta analyses and the interim analysis of the RECORD trial. …”
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  3. 1903

    Piperine: Chemical, biological and nanotechnological applications by Quijia Christian Rafael, Araujo Victor Hugo, Chorilli Marlus

    Published 2021-06-01
    “…This review also includes advances in the development of nanosystems containing PIP, including liposomes, micelles, metal nanoparticles, nanofibers, polymeric nanoparticles, and solid-lipid nanoparticles. Finally, we discuss different in vitro and in vivo studies to evaluate the biological activity of this drug, as well as some methods for the synthesis of nanosystems and their physical characteristics.…”
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  4. 1904

    Protective effect of alirocumab, a PCSK9 inhibitor, on the sciatic nerve of rats with diabetic peripheral neuropathy by Na Cui, Yonghao Feng, Ming Wang, Xiuyan Lu, Yongmei Huang, Yinghui Chen, Xiaohong Shi

    Published 2024-03-01
    “…Proprotein convertase subtilisin-like/Kexin 9 inhibitor (PCSK9) inhibitors are a new type of lipid-lowering drug currently in clinical use. The role of PCSK9 in diabetic peripheral neuropathy is still unclear. …”
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    Article
  5. 1905

    Peroxisome Proliferator-Activated Receptors and the Heart: Lessons from the Past and Future Directions by Wang-Soo Lee, Jaetaek Kim

    Published 2015-01-01
    “…The main role of PPARs is to regulate the expression of genes involved in lipid and glucose metabolism. Several studies have demonstrated that PPAR agonists improve dyslipidemia and glucose control in animals, supporting their potential as a promising therapeutic option to treat diabetes and dyslipidemia. …”
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    Article
  6. 1906

    PPARγ and Its Role in Cardiovascular Diseases by Mini Chandra, Sumitra Miriyala, Manikandan Panchatcharam

    Published 2017-01-01
    “…Peroxisome proliferator-activated receptor Gamma (PPARγ), a ligand-activated transcription factor, has a role in various cellular functions as well as glucose homeostasis, lipid metabolism, and prevention of oxidative stress. …”
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  7. 1907

    Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology by Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu

    Published 2025-01-01
    “…Abstract A new type of nonapoptotic, iron-dependent cell death induced by lipid peroxidation is known as ferroptosis. Numerous pathological processes, including inflammation and cancer, have been demonstrated to be influenced by changes in the ferroptosis-regulating network. …”
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    Article
  8. 1908

    Immunomodulation as the main characteristic of vegetable oils: a review by D.P. Tres, S.T. Nicolau, T.S. Ayala, R.A. Menolli

    Published 2024-09-01
    “…The benefits in their consumption by the population worldwide is proven, mainly promoting the balance of the lipid profile, cardiovascular aspects, decrease in blood pressure, and healing effects when used topically. …”
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    Article
  9. 1909

    Oral Verruciform Xanthoma: A Case Report and Literature Review by Akshay Shetty, Kourosh Nakhaei, Yogesh Lakkashetty, Maryam Mohseni, Iman Mohebatzadeh

    Published 2013-01-01
    “…Histopathologically, VX is diagnosed by presence of lipid-laden foam cells in papillary region of connective tissue. …”
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    Article
  10. 1910

    Oxidative Stability and Quality Parameters of Veal During Ageing by Mateja Lušnic Polak, Mojca Kuhar, Iva Zahija, Lea Demšar, Tomaž Polak

    Published 2023-01-01
    “…Ageing time enhanced sensory-evaluated tenderness, juiciness, aroma, and flavour. The amount of the lipid oxidation product determined as thiobarbituric acid reactive substance content remained unchanged; in contrast, the amount of protein carbonyls increased, without compromising veal quality.…”
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  11. 1911

    Mitochondrial Dysfunction as a Therapeutic Target in Diabetic Cardiomyopathy: Progress and Prospects by Feng Zhang, Zhuqing Li, Yanxin Wang, Chao Li, Chengzhi Lu

    Published 2025-01-01
    “…Recent studies have highlighted the crucial roles of mitochondrial dysfunction in the pathogenesis of DCM, including aspects such as glucose-lipid metabolic disorder, oxidative stress damage, calcium regulation disorder, respiratory chain uncoupling, kinetic imbalance, and mitochondrial DNA damage. …”
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    Article
  12. 1912

    Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice by Jin Han Yang, Thi Thu Tra Tran, Van Viet Man Le

    Published 2020-01-01
    “…Addition of high-polydextrose snack to the high-fat diet resulted in significant reduction in the liver weight, the accumulation of lipid droplets in liver, and the liver damage of hyperlipidemic mice in comparison with the high-fat diet. …”
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  13. 1913

    Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro by Jun-Qin Li, Hui-Jie Jiang, Xiu-Yun Su, Li Feng, Na-Zhi Zhan, Shan-Shan Li, Zi-Jie Chen, Bo-Han Chang, Peng-Zhen Cheng, Liu Yang, Guo-Xian Pei

    Published 2022-01-01
    “…Further, Schwann cells regulate amino acid metabolism and lipid metabolism in preosteoblasts. These findings unveil the mechanism for Schwann cells to promote osteogenesis where Mif is a key factor.…”
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    Article
  14. 1914

    PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways by Jordi Camps, Anabel García-Heredia, Anna Rull, Carlos Alonso-Villaverde, Gerard Aragonès, Raúl Beltrán-Debón, Esther Rodríguez-Gallego, Jorge Joven

    Published 2012-01-01
    “…The paraoxonase (PON) group of enzymes, composed of PON1, PON2, and PON3, play an important role in decreasing oxidative stress by degrading lipid peroxides. PON1 synthesis is upregulated by PPAR. …”
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  15. 1915

    Role of Toll-Like Receptors and Their Downstream Molecules in the Development of Nonalcoholic Fatty Liver Disease by Kouichi Miura, Ekihiro Seki, Hirohide Ohnishi, David A. Brenner

    Published 2010-01-01
    “…On the other hand, these mediators alter lipid metabolism, insulin signaling, and cell survival. …”
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    Article
  16. 1916

    Role of Leukotrienes on Protozoan and Helminth Infections by Alexandre P. Rogerio, Fernanda F. Anibal

    Published 2012-01-01
    “…Leukotrienes (LTs), formed by the 5-lipoxygenase-(5-LO-) catalyzed oxidation of arachidonic acid, are lipid mediators that have potent proinflammatory activities. …”
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    Article
  17. 1917

    Clinical Trials of Probiotic Strains in Selected Disease Entities by Ruth Dudek-Wicher, Adam Junka, Justyna Paleczny, Marzenna Bartoszewicz

    Published 2020-01-01
    “…A number of studies prove that probiotics strengthen cognitive functions, reduce anxiety, and regulate the lipid metabolism in the human body. Probiotics used in humans are most often of the Lactobacillus and Bifidobacterium species. …”
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  18. 1918
  19. 1919

    Effects of intramuscular fat on the flavor of fresh sheep and goat meat: Recent insights into pre-mortem and post-mortem factors by Tianyu Su, Yu Fu, Jingjie Tan, Mohammed Gagaoua, Kathrine H. Bak, Olugbenga P. Soladoye, Zhongquan Zhao, Yongju Zhao, Wei Wu

    Published 2025-01-01
    “…The present review aims to discuss the relationships between IMF and flavor through lipid composition and fatty acid (FA) distribution, provide an overview of characteristic flavor compounds affecting the flavor of sheep and goat meat, and shed light on the impacts of pre-mortem and post-mortem factors on meat flavor attributed to changes in FAs and flavor compounds. …”
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  20. 1920

    Imaging and MR Spectroscopy in Papillary Craniopharyngioma by Ashima Mahajan, Bheru Dan Charan, Sushant Agarwal, Vinay Goel, Leve Joseph Devarajan Sebastian, Vaishali Suri, Ashish Suri, Ajay Garg

    Published 2024-05-01
    “…In this context, we report three biopsy-proven cases of suprasellar papillary craniopharyngioma where the MRS spectra derived from the solid component exhibited noticeable lipid peaks alongside reduced levels of choline and NAA. …”
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