-
1861
Citrus Flavonoid Effects on Obesity
Published 2017-04-01“…The use of phytochemicals as a safe and natural alternative to treat obesity is under current investigation as citrus flavonoids haven been shown to monitor energy intake versus expenditure, regulate lipid metabolism and adipose tissue, and inhibit amylase function. …”
Get full text
Article -
1862
Insulin Resistance and Endothelial Dysfunction Constitute a Common Therapeutic Target in Cardiometabolic Disorders
Published 2016-01-01“…Combined and expletive treatment of hypertension, lipid disorders, and insulin resistance with nonpharmacological interventions and conventional pharmacotherapy may inhibit the transformation of metabolic disturbances to fully developed cardiovascular disease. …”
Get full text
Article -
1863
Peroxisome Proliferator-Activated Receptors and Acute Lung Injury
Published 2007-01-01“…PPARs regulate several metabolic pathways by binding to sequence-specific PPAR response elements in the promoter region of target genes, including lipid biosynthesis and glucose metabolism. Recently, PPARs and their respective ligands have been implicated as regulators of cellular inflammatory and immune responses. …”
Get full text
Article -
1864
Bile Acids: Key Regulators and Novel Treatment Targets for Type 2 Diabetes
Published 2020-01-01“…Furthermore, we provide an overview of the mechanisms underlying the role of bile acids in glucose and lipid metabolism, as well as the occurrence and development of T2DM. …”
Get full text
Article -
1865
The Renoprotective Actions of Peroxisome Proliferator-Activated Receptors Agonists in Diabetes
Published 2012-01-01“…Pharmaceutical agonists of peroxisome proliferator-activated receptors (PPARs) are widely used in the management of type 2 diabetes, chiefly as lipid-lowering agents and oral hypoglycaemic agents. …”
Get full text
Article -
1866
In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea
Published 2018-06-01“…Organic extracts of different organs (leaf, stem and root) of these medicinal plants obtained in n-hexane, chloroform, n-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC) of both selected medicinal plants was also evaluated. …”
Get full text
Article -
1867
Intricating connections: the role of ferroptosis in systemic lupus erythematosus
Published 2025-02-01“…Although ferroptosis, an iron-dependent form of cell death, has numerous pathophysiological features similar to those of SLE, such as intracellular iron accumulation, mitochondrial dysfunction, lipid metabolism disorders and concentration of damage associated-molecular patterns (DAMPs), only a few reports have demonstrated that ferroptosis is involved in SLE progression and that the role of ferroptosis in SLE pathogenesis continues to be neglected. …”
Get full text
Article -
1868
Metabolism of bile acids, liver diseases and microbiome
Published 2018-08-01“…Bile acids are important signaling molecules that regulate lipid and glucose metabolism. Enterohepatic circulation of BA plays the central role in nutrient absorption and metabolic regulation. …”
Get full text
Article -
1869
Targeting Polymorphonuclear Leukocytes in Acute Myocardial Infarction
Published 2007-01-01“…This review, indeed, presents and discusses new data on one of the lipid kinase, the phosphoinositide 3-kinase gamma (PI3Kγ), and its role in neutrophil recruitment during AMI.…”
Get full text
Article -
1870
Chronic cholecystitis at patients with the various trophological status: mechanisms and feature of clinical course
Published 2014-09-01“…Food behavior analysis was carried out, clinical features, anthopometry were determined, bile lipid spectrum, serum content of leptin and insulin were studied by enzyme-linked immunoassay.Results. …”
Get full text
Article -
1871
Exploring the effects of perfluorooctanoic acid (PFOA) and tetrabromobisphenol A (TBBP-A) on silkworm from the insights of metabolome
Published 2025-01-01“…Exposure to these chemicals significantly altered metabolic profiles, leading to disruptions in pathways related to lipid, carbohydrate, and amino acid metabolism. These findings suggest that PFOA and TBBP-A disrupt crucial metabolic processes in silkworms, indicating potential toxicity and prompting further investigation into their effects on human health and the environment. …”
Get full text
Article -
1872
Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease
Published 2014-01-01“…Excess nutrient intake resulting in adipose tissue expansion triggers lipid release and aberrant adipokine, cytokine and chemokine production, and signaling that ultimately lead to adipose tissue inflammation, a hallmark of obesity. …”
Get full text
Article -
1873
Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion
Published 2011-01-01“…Most patients with SH suffer primary or genetic abnormality in lipid metabolism in combination with a precipitating factor such as uncontrolled diabetes mellitus, alcoholism, and drug intake. …”
Get full text
Article -
1874
Retinoid Therapy in a Case of Harlequin Ichthyosis with a Short Literature Review
Published 2024-01-01“…Harlequin ichthyosis (HI) is a genetically inherited epidermal disorder due to the mutation of the ABCA12 gene, which is responsible for lipid transportation, and presents with large keratinised scales characterised by deep erythematous fissures, with ectropion and eclabium. …”
Get full text
Article -
1875
Calcium Signaling in the Ventricular Myocardium of the Goto-Kakizaki Type 2 Diabetic Rat
Published 2018-01-01“…The GK rat is a widely used nonobese, nonhypertensive genetic model of T2DM which is characterized by insulin resistance, elevated blood glucose, alterations in blood lipid profile, and cardiac dysfunction.…”
Get full text
Article -
1876
Utilization of Cassava as Substitues of Wheat Flour for Common Carp Diets
Published 2007-08-01“…The study showed that growth rate, protein retention, lipid retention and feed efficiency of fish fed diets containing cassava meal up to 50% substitution levels were significantly (p…”
Get full text
Article -
1877
Dietary omega-3 fatty acids affect the growth performance of broiler chickens reared at high stocking density
Published 2025-01-01“…The apparent metabolizable energy (AME), digestibility of crude protein (CP), organic matter (OM), and lipid of experimental diets, were measured from days 30 to 37 of age. …”
Get full text
Article -
1878
Fasting-Evoked En Route Hypoglycemia in Diabetes (FEEHD): An Overlooked Form of Hypoglycemia in Clinical Practice
Published 2018-01-01“…Many patients with diabetes opt to fast for lab tests, especially for lipid profiles, thus missing breakfast. In parallel, recent studies and international guidelines have indicated that routine fasting for lipid panels may not be necessary. …”
Get full text
Article -
1879
Studying sex differences in responses to fibroblast growth factor 21 administration in obese mice consuming a sweet-fat diet
Published 2023-07-01“…The aim of this study was to compare the effects of FGF21 on body weight, food preferences and glucose and lipid metabolism in C57Bl/6J male and female mice with SFD-induced obesity. …”
Get full text
Article -
1880
The Validation of a Novel, Sex-Specific LDL-Cholesterol Equation and the Friedewald, Sampson-NIH, and Extended-Martin–Hopkins Equations Against Direct Measurement in Korean Adults...
Published 2025-01-01“…<b>Background/Objectives</b>: The currently established equations for calculating low-density lipoprotein cholesterol (LDLc) do not reflect the sex-specific differences in lipid metabolism. We aimed to develop a sex-specific LDLc equation (SSLE) and validate it with three established equations (Friedewald, Sampson-NIH, and ext-Martin–Hopkins) against direct LDLc measurement in Korean adults. …”
Get full text
Article