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1761
Mitochondrial Dynamics: Functional Link with Apoptosis
Published 2012-01-01“…Mitochondria participate in a variety of physiologic processes, such as ATP production, lipid metabolism, iron-sulfur cluster biogenesis, and calcium buffering. …”
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1762
Ectopic Fat and Insulin Resistance: Pathophysiology and Effect of Diet and Lifestyle Interventions
Published 2012-01-01“…Not the triglycerides per se but the accumulation of intermediates of lipid metabolism in organs, such as the liver, skeletal muscle, and heart seem to disrupt metabolic processes and impair organ function. …”
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1763
Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report
Published 2024-09-01“…While intravenous insulin typically treats the dyslipidemia in these cases, the role of lipid-lowering agents to prevent adverse outcomes in patients not responding to insulin warrants further investigation. …”
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1764
Progressive Dyspnea in a 40-Year-Old Man Caused by Giant Mediastinal Thymolipoma
Published 2016-01-01“…Clinical evaluation revealed a giant mass of lipid density filling almost the entire left hemithorax with mediastinal shift. …”
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1765
Dissection of the Interplay between Class I PI3Ks and Rac Signaling in Phagocytic Functions
Published 2010-01-01“…Molecular mechanisms underlying these processes are starting to emerge and point to the interplay between two families of crucial proteins: the PI3K lipid kinases and the Rac GTPases. This review focuses on how these two protein families contribute to migration, phagocytosis, and reactive oxygen species production, as well as their epistatic and feedback relations that finely tune these crucial aspects of the immune response.…”
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1766
2024 Polish recommendations for the management of familial hypercholesterolemia in children and adolescents
Published 2024-11-01“…This document is an update of the 2014 Position Paper of the Lipid Expert Forum.…”
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1767
The Current Knowledge of the Role of PPAR in Hepatic Ischemia-Reperfusion Injury
Published 2012-01-01“…Peroxisome proliferator-activated receptors (PPARs) are major regulators of lipid metabolism and inflammation. In this paper, we review the PPAR signaling pathways and present some of their lesser-known functions in liver regeneration. …”
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1768
Role of PPAR𝛼 in Hepatic Carbohydrate Metabolism
Published 2010-01-01“…PPAR𝛼 is the master regulator of lipid metabolism during fasting, but evidence is emerging for a role of PPAR𝛼 in balancing glucose homeostasis as well. …”
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1769
Response to: Prescribed Minimum Benefits complaints: A 5-year retrospective review
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1770
Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case-Control Study
Published 2023-01-01“…BMI (kg/m2) and blood pressure (BP) were measured. HbA1c (%) and lipid profile evaluation was performed on fasting blood samples. …”
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1771
Winery By-Products In Vitro and In Vivo Effects on Atherothrombotic Markers: Focus on Platelet-Activating Factor
Published 2025-01-01“…Wine contains micro-constituents of proper quality and quantity that exert cardioprotective actions, partly through inhibiting platelet-activating factor (PAF), a potent inflammatory and thrombotic lipid mediator. However, wine cannot be consumed extensively due to the presence of ethanol. …”
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1772
Physicochemical properties, structure, growth-promoting and antioxidant activities of Glycyrrhiza leaf polysaccharides modified by fermentation
Published 2025-01-01“…FGLP exhibited superior protective effects against lipid peroxidation and cell death induced by AAPH. …”
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1773
Effects of Resistant Starch on Patients with Chronic Kidney Disease: A Systematic Review and Meta-Analysis
Published 2022-01-01“…However, there was no significant change of RS on hs-CRP, serum creatinine, blood urea nitrogen (BUN), blood paracresol sulfate, and blood lipid. Conclusions. The intake of RS reduced the serum IS, serum phosphorus, IL-6, and uric acid levels significantly in dialysis patients, while hs-CRP, serum creatinine, BUN, serum paracresol sulfate, and blood lipid showed no significant changes.…”
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1774
6-Gingerol Normalizes the Expression of Biomarkers Related to Hypertension via PPARδ in HUVECs, HEK293, and Differentiated 3T3-L1 Cells
Published 2018-01-01“…In HEK293 cells, the expression of the epithelial sodium channel (ENaC) protein was reduced by 6-gingerol. Lipid accumulation was attenuated by 6-gingerol treatment in differentiated 3T3-L1 cells. …”
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1775
Cardiometabolic risk factors in the Swedish Werlabs cohort based on self-initiated health screening: cohort profile
Published 2025-01-01“…In an analysis restricted to 621 individuals with recorded blood pressure data between the age of 40 and 70 years and without existing cardiovascular disease, diabetes or kidney disease, 35,4% were classified as high or very high cardiovascular risk according to the 2021 ESC guidelines on cardiovascular disease prevention and with lipid levels that made them eligible for lipid-lowering therapy.Future plans The Werlabs cohort comprises a rather healthy and young population that can provide opportunities for future studies on individuals undergoing self-initiated health examinations and has the potential to impact treatment of cardiometabolic risk factors.…”
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1776
Relationship between dietary intake and atherogenic index of plasma in cardiometabolic phenotypes: a cross-sectional study from the Azar cohort population
Published 2025-02-01“…Conclusion The study found weak but meaningful correlations between energy, carbohydrate, and protein intake and AIP in the MUHO phenotype and between carbohydrate and lipid intake and AIP in the MHO phenotype. This highlights the role of energy and carbohydrates in AIP within specific subgroups. …”
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1777
Pipeline for development of acylated peptide based CGRP receptor antagonist with extended half-life for migraine treatment
Published 2025-01-01“…Our findings demonstrate that lipidation can improve hαCGRP8-37 pharmacokinetics while maintaining hαCGRP antagonism, thus demonstrating potential for a peptide-based migraine treatment strategy.…”
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1778
Mechanism of TGIF1 on glycolipid metabolism disorders in mice with type 2 diabetes
Published 2025-01-01“…Staining assays were performed to observe liver tissue pathology and lipid accumulation. Liver function and oxidative stress were measured. …”
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1779
Counteracting negative effects of salinity on Lepidium sativum L. seedlings by prepared biochar
Published 2024-10-01“…Biochar alleviated the hazardous effects of NaCl on L. sativum by decreasing free radicle formation and lipid peroxidation, thereby enhancing germination and early growth. …”
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1780
The effect of different amounts of bıotin in broilers' ration on growth performance and fatty liver syndrome
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