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The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota
Published 2024-12-01“…The control diet (FO) contained only fish oil as a source of lipids, EPA and DHA fatty acids, while three experimental diets were used where fish oil was replaced at 67% by one of the following microalgae biomass blends: Microchloropsis gaditana and Isochrysis sp. …”
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1322
Mass‐Guided Single‐Cell MALDI Imaging of Low‐Mass Metabolites Reveals Cellular Activation Markers
Published 2025-02-01“…Abstract Single‐cell MALDI mass spectrometry imaging (MSI) of lipids and metabolites >200 Da has recently come to the forefront of biomedical research and chemical biology. …”
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1323
Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension
Published 2013-01-01“…We recruited 3137 nondiabetic individuals whose age, body mass index (BMI), glucose levels, blood pressure (BP), lipids, hemoglobin A1C (HbA1c), baPWV, and insulin levels were measured. …”
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1324
Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment
Published 2025-01-01“…<i>In silico</i> annotation and gene ontology analysis highlighted the activation of ethanol oxidation, ROS regulation, retinoic acid metabolism, and steroid hormone metabolism, as well as in the metabolism of lipids, amino acids, and nucleotides, and pinpointed potential new osteogenic drivers like AOX1 and ADH1A. …”
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1325
Evaluation of Arbuscular Mycorrhizal Fungi Capacity to Alleviate Abiotic Stress of Olive (Olea europaea L.) Plants at Different Transplant Conditions
Published 2014-01-01“…These conditions generate reactive oxygen species (ROS) in plant tissues causing oxidation of proteins and lipids among others. Some plants have developed adaptive mechanisms to counteract such adverse conditions such as symbiotic association with arbuscular mycorrhizal fungi (AMF). …”
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1326
Optimization of the Process for Defatting Sea Cucumber Powder by Supercritical CO2 Extraction and Its Effect on Volatile Flavor Compounds
Published 2025-02-01“…Therefore, supercritical CO2 extraction can effectively separate lipids from sea cucumber powder, while removing a large amount of volatile components with fishy odors.…”
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1327
Correlates of and Body Composition Measures Associated with Metabolically Healthy Obesity Phenotype in Hispanic/Latino Women and Men: The Hispanic Community Health Study/Study of L...
Published 2019-01-01“…., obesity and absence of cardiometabolic abnormalities: favorable levels of blood pressure, lipids, and glucose) experience lower risk of cardiovascular disease compared with those with “metabolically at-risk obesity” (MAO) phenotype (i.e., obesity with concurrent cardiometabolic abnormalities). …”
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1328
Effects of Omega-3 Fatty Acid in Nonalcoholic Fatty Liver Disease: A Meta-Analysis
Published 2016-01-01“…A meta-analysis was conducted to assess the effect of omega-3 fatty acid supplementation (n-3 PUFAs) in lowering liver fat, liver enzyme (alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT) levels), and blood lipids (triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL), and low density lipoprotein (LDL)) in patients with nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH). …”
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1329
Investigation of the physicochemical factors affecting the in vitro digestion and glycemic indices of indigenous indica rice cultivars
Published 2025-01-01“…FTIR spectral analysis revealed prominent bands at 3550-3200, 2927-2935, 1628-1650, 1420-1330, and 1300-1000 cm−1, which correspond to –OH groups, C=O, C=C, and C–OH stretches, and H–O–H and –CH bending vibrations, confirming the presence of starch, proteins, and lipids. Additionally, the FTIR ratio R(1047/1022) confirmed the ordered structure of the amylopectin. …”
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1330
Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity
Published 2025-01-01“…MTX primarily affected the processes of protein digestion and absorption, mineral absorption, membrane transport, production of aminoacyl-transfer RNA (tRNA), metabolism of nucleotides, lipids, and amino acids, as well as autophagy. Additionally, MTX increased Romboutsia, Enterococcus, and Turicibacter abundances and lowered norank_f__Muribaculaceae, Alistipes, Odoribacter, norank_f__Lachnospiraceae, norank_f__Ruminococcaceae, norank_f__Oscillospiraceae, unclassified_f__Ruminococcaceae, NK4A214_group, Colidextribacter, norank_f__norank_o__Clostridia_vadinBB60_group, Rikenella, and Anaerotruncus abundances. …”
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1331
Serum metabolic profiles in quails: Effects of age, breed, and sex
Published 2025-01-01“…At 20 days of age (D20), quails had high levels of serum thymidine and alpha-D-glucose, while at 70 days of age (D70), the lipids, including 3-isothujone, 15-deoxy-d-12,14-PGJ2, and 2-aminobut-2-enoate dominated the serum. …”
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1332
The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach
Published 2019-01-01“…The development of metabolic syndrome-associated renal dysfunction is exacerbated by a number of factors including dyslipidemia, ectopic deposition of lipids and their toxic metabolites, impairment of lipid metabolism, and insulin resistance. …”
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1333
Relationship between prenatal metals exposure and neurodevelopment in one-year-old infants in the CLIMB study
Published 2025-02-01“…Methods: This study included 189 mother-infant pairs from the Complex Lipids in Mothers and Babies (CLIMB) cohort. The concentrations of 21 metallic elements and 2 metalloids in umbilical cord blood (UCB) serum were measured using inductively coupled plasma mass spectrometry (ICP-MS). …”
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1334
Risk Factors Associated with Cardiac Autonomic Modulation in Obese Individuals
Published 2020-01-01“…HOMA-IR (β = 0.141, p=0.003) and the percentage of lipids ingested (β = −0.030, p=0.043) were negatively associated with LF/HF. …”
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1335
Aldehyde Dehydrogenase 2 rs671 Polymorphism is Associated with Susceptibility of Coronary Atherosclerosis in Patients with Hypertension
Published 2025-02-01“…Atherosclerosis is a chronic inflammatory disease caused by lipid deposition in the blood vessels, and aldehyde dehydrogenase 2 (ALDH2) is involved in this process. …”
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1336
A Review of Marine Bacterial Intracellular and Extracellular Bioactive Compounds as Novel Antibacterial and Anti-Inflammation Agents
Published 2025-01-01“…A crucial resource in the ongoing search for novel peptides, proteins, lipids, nucleosides, enzymes, alkaloids, polyketides, and terpenoids is the diversity of marine bacterium strains. …”
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1337
The relationship between walking speed and changes in cardiovascular risk factors during a 12-day walking tour to Santiago de Compostela: a cohort study
Published 2012-05-01“…We report the relationship between walking speed and changes in cardiovascular risk factors in participants of a 12-day walking tour to Santiago de Compostela.Design Prospective cohort study.Setting Single-centre study with healthy middle-aged volunteers.Participants Healthy middle-aged men (n=15) and women (n=14). Subjects using lipid-lowering medication were excluded.Intervention Participants walked 281±10 km of the classical route to Santiago de Compostela in 12 days in 2009.Primary and secondary outcome measures Walking speed was recorded and blood pressure, weight, waist circumference, lipids and glucose were measured every other day. …”
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1338
An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines
Published 2024-10-01“…Gangliosides are glycosphingolipids composed of a sialylated glycan head group and a ceramide backbone. These anionic lipids form lipid rafts and play crucial roles in regulating various proteins involved in signal transduction, adhesion, and cell–cell recognition. …”
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High HDL-C and high LDL-C are risk factors of pterygium in a population-based cross-sectional study in Southern China: the Dongguan Eye Study
Published 2022-06-01“…Objectives To investigate the relationship between serum lipids and pterygium in a large-scale rural population aged 40 years or older from Southern China.Study design The Dongguan Eye Study was a cross-sectional population-based study from September 2011 to February 2012.Setting The area was set in the rural area of Dongguan, Southern China.Participants Adult rural population aged 40 or older.Methods Participants underwent physical, haematological and ophthalmic examinations.Primary and secondary outcome measures The frequency and risk factors of pterygium.Results A total of 11 357 participants were eligible for inclusion and 8952 (78.8%) participants were enrolled for the systemic and ophthalmic examinations. …”
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Machine learning-based plasma metabolomics for improved cirrhosis risk stratification
Published 2025-02-01“…Pathway enrichment analysis revealed that disruptions in lipid and amino acid metabolism play a central role in the progression of cirrhosis. …”
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