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1241
Liposomal Formulations: A Recent Update
Published 2024-12-01“…Drug encapsulation can be optimized by creating lipid compositions that match a drug’s charge and hydrophobicity. …”
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1242
Recent approaches in the drug research and development of novel antimalarial drugs with new targets
Published 2023-03-01“…The protein kinases, choline transport inhibitors, dihydroorotate dehydrogenase inhibitors, isoprenoid biosynthesis inhibitors, and enzymes involved in the metabolism of lipids and replication of deoxyribonucleic acid, are among the most fascinating antimalarial target proteins presently being investigated. …”
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1243
Cardiovascular Risk Awareness, Exercise Practices and Metabolic Outcomes among Patients with Diabetes Mellitus in Northern Nigeria: A Cross-sectional, Multicentre Study
Published 2024-04-01“…Mean body mass index (BMI), blood pressure (BP), fasting blood glucose, serum haemoglobin A1C (HbA1c), lipid profile, urea, creatinine and uric acid were then compared among participant groups. …”
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1244
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling
Published 2025-01-01“…Furthermore, plasma membrane lipids were investigated via confocal microscopy, revealing reduced cholesterol and lipid rafts. …”
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1245
RED light promotes flavonoid and phenolic accumulation in Cichorium spp. callus culture as anti-candida agent
Published 2025-01-01“…The antifungal activity was assessed by determining the effects on acid-soluble phosphorus, total lipids, and soluble proteins in the Candida cells. …”
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1246
Biochemistry of the Thrombin-Like TLBpic and Its Purification from Bothrops pictus “Jergon de la Costa” (Reptilia: Viperidae)
Published 2019-01-01“…Within the simple substances, we have free amino acids, peptides, nucleotides, carbohydrates, lipids, and biogenic amines (organic molecules) as well as cations and anions (inorganic constituents). …”
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1247
Heart rate variability, a potential assessment tool for identifying anxiety, depression, and sleep disorders in elderly individuals
Published 2025-01-01“…Variables assessed included age, sex, body mass index (BMI), fasting blood glucose, glycated hemoglobin (HbA1c), blood lipids, blood pressure, heart rate, and histories of smoking and alcohol consumption. …”
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1248
The Function of Two <i>Brassica napus</i> β-Ketoacyl-CoA Synthases on the Fatty Acid Composition
Published 2025-01-01“…Various types of fatty acid products are used to build lipid molecules, such as oils, suberin, wax, and membrane lipids. …”
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1249
Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Af...
Published 2018-01-01“…Upon palmitic acid stimulation, intracellular contents of lipids, as well as the expression and activity of three key molecules in thyroid hormone synthesis (i.e., thyroglobulin, sodium iodide symporter, and thyroperoxidase), were determined in human primary thyrocytes. …”
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1250
Serum PCSK9 Correlates with PTX3 and Apolipoproteins B, A1, and C3 Concentrations in Patients with Type 2 Diabetes
Published 2021-01-01“…Our results indicate that circulating PCSK9 is significantly associated with inflammation marker PTX3 as well as atherogenic lipids and apolipoproteins C3, B100, and B48, which might be of value in understanding interactions between development of atherosclerosis and inflammatory state in DM2 patients.…”
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1251
Evaluation of enzymatic hydrolysis of palm kernel meal in largemouth bass (Micropterus salmoides)
Published 2025-04-01“…The control diet, labeled as SBM, was formulated to contain approximately 46 % crude protein and 13 % crude lipids. Experimental diets substituted 5 % soybean meal and 3 % wheat flour with 5 % palm kernel meal or enzymatic hydrolysis of palm kernel meal, and 3 % cotton protein concentrate (CPC) labeled as PKM and EPKM. …”
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1252
Metabolic profile of blood serum in experimental arterial hypertension
Published 2023-09-01“…To determine specific markers of diseases, various omics technologies are applied, including metabolomics, which makes it possible to evaluate the content of low-molecular compounds – amino acids, lipids, carbohydrates, nucleic acids fragments – in biological samples available for clinical analysis (blood and urine). …”
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1253
Use of ascorbic acid (vitamin C) and alpha tocopherol (vitamin E) as adjuvants in the treatment of neuropathic pain
Published 2025-01-01“…BACKGROUND AND OBJECTIVES: High concentrations of free radicals can damage nucleic acids, proteins and lipids and their accumulation may be involved in hypersensitivity to pain. …”
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1254
Characterization of food wastes from the hotel industry as a potential feedstock for energy production
Published 2025-03-01“…The average feedstock characteristics were observed to be moisture content (6.0%, p < .001, R2 = 90.70 %), total solid (93.7%, p < .001, R2 = 99.97 %), volatile solid (84.3%, p < .001, R2 = 99.80 %), ash content (4.2%, p = .005, R2= 48.54 %), fixed carbon (5.4%, p < .001, R2 = 88.61%), nitrogen (3.6%, p = .04, R2 = 36.81 %), carbon to nitrogen ratio C/N (4.0), crude protein (22.4%, p = .004, R2 = 49.36 % ), crude lipids (12.1%, p < .001, R2 = 89.06 %), total organic carbon (44%, p < . 001, R2 = 94.70%), potassium (0.6%), sodium (1.2%), calcium (0.2%), and phosphorus (0.4%). …”
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1255
Molecular genetic and morphological characteristics of Micractinium thermotolerans and M. inermum (Trebouxiophyceae, Chlorophyta) from pyroclastic deposits of the Kamchatka Peninsu...
Published 2024-11-01“…In addition, cells with colorless lipid droplets were detected in aging cultures of both species. …”
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1256
Influence of Age at Diagnosis and Time-Dependent Risk Factors on the Development of Diabetic Retinopathy in Patients with Type 1 Diabetes
Published 2016-01-01“…The influence of age at diagnosis, glycemic control, duration of diabetes, sex, blood pressure, lipids, BMI, and smoking is analyzed using Cox univariate and multivariate models with fixed and time-dependent variables. …”
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1257
Utilization of edible poultry slaughter residues: A chicken-liver hydrolysate with glucose-lowering ability and upregulating glycogenesis in type II diabetes
Published 2025-01-01“…In db/db mice, CLH supplementation improved insulin resistance, as shown by OGTT assay, HOMA-IR value and serum glucose levels, while also reducing serum lipids and liver damage indices (p<0.05). Additionally, CLH ameliorated (p<0.05) decreased hindlimb-gastrocnemius weight, and liver lipid contents, oxidative stress (sera and liver) and inflammatory cytokines. …”
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1258
The Role of Nutrients in Supporting The Immune System Against Viral Infection; Newly Emerged Coronavirus (COVID19): A Narrative Review
Published 2020-05-01“…The macronutrients such as carbohydrates, lipids, and proteins are essential for cells to generate energy and participate in immune function as well. …”
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1259
Unveiling cellular changes in leukaemia cell lines after cannabidiol treatment through lipidomics
Published 2025-01-01“…Abstract The present study was aimed at revealing the metabolic changes that occurred in the cellular lipid pattern of acute and chronic myeloid leukaemia cells following treatment with cannabidiol (CBD). …”
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1260
Network pharmacology and molecular analysis of mechanisms underlying the therapeutic effects of Rhubarb in treating atherosclerosis and abdominal aortic aneurysm
Published 2025-02-01“…The analysis indicated that Rhubarb may be effective in treating AS/AAA through processes such as lipids, atherosclerosis, extracellular matrix catabolism, collagenolytic metabolic processes, and the extracellular environment. …”
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