Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer by Claudia Duranti, Jessica Iorio, Valeria Manganelli, Giacomo Bagni, Rossella Colasurdo, Tiziano Lottini, Michele Martinelli, Chiara Capitani, Giulia Boso, Franco Nicolas D’Alessandro, Maurizio Sorice, Andrea Becchetti, Roberta Misasi, Tina Garofalo, Annarosa Arcangeli

“…Our study provides evidence that the complex formed by the hERG1 potassium channel and the β1 subunit of integrin receptors preferentially localizes in Lipid Rafts (LRs) in Pancreatic Ductal Adenocarcinoma (PDAC) cell lines and primary samples. …”
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Negative association between 15 obesity- and lipid-related indices and testosterone in adult males: a population based cross-sectional study by Wei Guo, Shuo Zhao, Qinzheng Chang, Jiajia Sun, Yidong Fan, Jikai Liu

“…Lipids in Health and Disease…”
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Decreased Sex Hormone-Binding Globulin Indicated Worse Biometric, Lipid, Liver, and Renal Function Parameters in Women with Polycystic Ovary Syndrome by Xi Luo, Xin-Ming Yang, Wang-Yu Cai, Hui Chang, Hong-Li Ma, Yan Peng, Xiao-Ke Wu

“…Metabolic parameters included biometric parameters, glucose and lipid panels, and liver and renal function parameters. …”
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Impaired RelA signaling and lipid metabolism dysregulation in hepatocytes: driving forces in the progression of metabolic dysfunction-associated steatotic liver disease by Yihuai He, Jinlian Jiang, Lili Ou, Yunfen Chen, Aikedaimu Abudukeremu, Guimei Chen, Weiwei Zhong, Zhigang Jiang, Nuerbiye Nuermaimaiti, Yaqun Guan

“…Impaired RelA signaling remodeled the ER stress response and lipid metabolism, and enhanced lipid accumulation and lipid toxicity. …”
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Low apolipoprotein A1 and high apolipoprotein B levels indicate specific lipid changes in treatment naïve early psoriatic arthritis by Kurt de Vlam, Rik Lories, M Van Mechelen, Sofia Pazmino, P Verschueren, Barbara Neerinckx, Lies Storms, Alla Ishchenko

“…Objectives To investigate serum lipid profile in early, treatment-naïve psoriatic arthritis (PsA) and to determine whether changes in classical lipids or apolipoproteins are specific to PsA.Methods Total cholesterol, non-high-density lipoprotein cholesterol (non-HDL-c), low-density lipoprotein cholesterol (LDL-c), HDL-c, triglycerides, apolipoprotein B (ApoB) and apolipoprotein A1 (ApoA1) were compared in newly diagnosed untreated PsA patients (n=75) to sex- and age-matched controls (healthy control (HC)) (n=61) and early untreated rheumatoid arthritis (RA) patients (n=50).Results Among classical lipid measurements, HDL-c levels were lower in PsA than in HC and RA (df 2, χ210, p=0.006, PsA vs HC p=0.013). …”
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DNA Methylation and Transcriptome Profiling Reveal the Role of the Antioxidant Pathway and Lipid Metabolism in <i>Plectropomus leopardus</i> Skin Color Formation by Yang Liu, Linna Wang, Zhentong Li, Linlin Li, Tangtang Ding, Shuai Chen, Pengfei Duan, Xinyi Wang, Yishu Qiu, Xiaoyu Ding, Yongsheng Tian

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Achieving prediabetes reversal in China: a nationwide longitudinal study on the role of blood glucose and lipid management in middle-aged and elderly adults by Hongguang Yang, Yao Liu, Zhenhe Huang, Guifang Deng

“…Additionally, evaluated blood lipid profiles reduced the odds of regression to NGR.ConclusionThis study underscores the influence of age, gender, abdominal obesity, LDL-C levels, FPG, HbA1c, and blood lipid profiles on the likelihood of regressing from prediabetes to NGR. …”
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Harmonious regulation flavor and lipid oxidation in dry-cured tenderloin through electrical stimulation: A study on lipase activity and sensory correlations by Lisha Lan, Li Chen, Xiaolin Zhong, Weiguo Cao, Ying Zhou, Jing Wan, Yuanyuan Liu, Qinjin Zhu

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The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration by Saman Heydari, Mohammad Barzegar-Jalali, Mostafa Heydari, Afsaneh Radmehr, Ana Cláudia Paiva-Santos, Maryam Kouhsoltani, Hamed Hamishehkar

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Lipid Deposition in Skeletal Muscle Tissues and Its Correlation with Intra-Abdominal Fat: A Pilot Investigation in Type 2 Diabetes Mellitus by Manoj Kumar Sarma, Andres Saucedo, Suresh Anand Sadananthan, Christine Hema Darwin, Ely Richard Felker, Steve Raman, S. Sendhil Velan, Michael Albert Thomas

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Serum Lipid and Glycemic Profile in HARRT-Naïve and HARRT-Exposed HIV Patients in Enugu State, Nigeria: A Case–Control Study by Esther A. Ekwe, Birinus A. Ezeala-Adikaibe, Basden Onwubere, Julius Okoye, Collins Ugwu, Chidinma B. Nwatu, Ijoma Chinweuba, Chidimma Orah-Okpala, Raphael Anakwue, Oladipupo O. Fasa, Celestine C. Okwara, Uchechi Q. Arinze, Paschal Njoku

“…Background: Although highly active antiretroviral therapy (HAART) has improved immunologic and virologic outcomes, as well as the quality of life of human immunodeficiency virus (HIV)-positive patients, it has worsened a wide range of metabolic derangements associated with HIV/AIDS. A wide range of lipid abnormalities and dysglycemia have been reported in patients on HARRT. …”
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Total flavonoids of Abelmoschus manihot ameliorate lipid deposition in HK-2 cells by inhibiting fatty acid uptake mediated by CD36 by Xiaofang Wang, Chenquan Tang, Yi Jiang, Yi Xue, Enchao Zhou

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The effect of magnesium supplementation on serum concentration of lipid profile: an updated systematic review and dose-response meta-analysis on randomized controlled trials by Mitra Hariri, Masoudreza Sohrabi, Ali Gholami

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Lipid Peroxidation-Mediated Inflammation Promotes Cell Apoptosis through Activation of NF-κB Pathway in Rheumatoid Arthritis Synovial Cells by Geng Yin, Ying Wang, Xiao-min Cen, Min Yang, Yan Liang, Qi-bing Xie

“…Our results indicated that products of lipid peroxidations, 4-HNE, may induce synovial intrinsic inflammations by activating NF-κB pathways and it may lead to cell apoptosis. …”
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SDZ MRL 953, A Novel Synthetic Lipid a Analogue, Induces Tolerance to the Lethal Effects of Endotoxin and Enhances Nonspecific Immunity by Charles Lam, Eberhard Schütze, Emmanuel Quakyi, Ekke Liehl, Peter Stütz

“…An attractive alternative appears to be the induction of hyporesponsiveness to LPS by synthetic lipid A analogues. SDZ MRL 953, a novel prototype of lipid A analogues. was examined for its ability to induce early-phase tolerance against experimental endotoxemia in mice following single or multiple administrations 2, 24, or 72 h before challenge. …”
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Boosting Therapeutic Effect of Turmeric, Coffee, and Chili Extracts Through Experimental Design and Encapsulation as Nanostructured Lipid Carriers for Novel Heath Supplements by Pratchaya Tipduangta, Phennapha Saokham, Jutamas Jiaranaikulwanitch, Siriporn Okonogi, Chadarat Ampasavate, Kanokwan Kiattisin

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Evaluation of the Obesity Prevention, Blood Glucose, and Blood Lipid Control of Vietnamese Rice Varieties in High-Fat Diet-Induced Obese Mice by Thuy Linh Nguyen, Khanh Son Trinh

“…The golden flower glutinous rice (GN), with low amylose and fiber content, gave worse blood lipid parameters than that of GM and LĐ. Histopathological studies of white adipose and liver tissues showed that LĐ and GM significantly reduced the symptoms of obesity and fatty liver compared with the others, especially compared to GN. …”
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Deficiency of the mitochondrial transporter SLC25A47 minimally impacts hepatic lipid metabolism in fasted and diet-induced obese mice by Brecht Attema, Montserrat A. de la Rosa Rodriguez, Evert M. van Schothorst, Sander Grefte, Guido JEJ. Hooiveld, Sander Kersten

“…Objective: The peroxisome proliferator-activated receptor-alpha (PPARα) plays a central role in lipid metabolism in the liver by stimulating the expression of hundreds of genes. …”
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Multispecies pasture diet and cow breed affect the functional lipid profile of milk across lactation in a spring-calving dairy system by Renata Kostovska, Gaetan Drouin, Joaquín J. Salas, Mónica Venegas-Calerón, Brendan Horan, John T. Tobin, Tom F. O'Callaghan, Sean A. Hogan, Alan L. Kelly, Laura G. Gómez-Mascaraque

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A Snake Venom-Secreted Phospholipase A2 Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis by Elbio Leiguez, Karina Cristina Giannotti, Mariana do Nascimento Viana, Márcio Hideki Matsubara, Cristina Maria Fernandes, José Maria Gutiérrez, Bruno Lomonte, Catarina Teixeira

“…MT-III, a snake venom GIIA sPLA2, which shares structural and functional features with mammalian GIIA sPLA2s, activates macrophage defense functions including lipid droplet (LDs) formation, organelle involved in both lipid metabolism and inflammatory processes. …”
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