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2701
Parametric and non-parametric estimation of reference intervals for routine laboratory tests: an analysis of health check-up data for 260 889 young men in the South Korean military
Published 2022-07-01“…Participants with obesity showed higher RIs for CBC, some liver function tests and some lipid profiles than participants without obesity.Conclusions Using data from healthy, male Korean soldiers in their 20s, we proposed the RIs for CBC and biochemical parameters, comparing parametric and non-parametric estimation. …”
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2702
Acyl-CoA Thioesterase 1 Contributes to Transition of Steatosis to Metabolic-Associated Steatohepatitis
Published 2024-01-01“…Experimental validation showed that downregulation of ACOT1 resulted in decreased lipid accumulation and prevention of MASH in vivo. …”
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2703
Characterization and ameliorative effects of Chenopodium murale hydroethanolic extract against diethylnitrosamine-induced hepato-renal damage and malfunction
Published 2023-12-01“…Results DEN has injurious effects, associated with elevated liver enzyme activities (AST, ALT and ALP), urea and creatinine in serum. Also, lipid peroxidation and nitric oxide were elevated markedly. …”
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2704
Hepatoprotective Effects of Crude Stem Bark Extracts and Solvent Fractions of Cordia africana against Acetaminophen-Induced Liver Injury in Rats
Published 2022-01-01“…Serum levels of the liver enzymes and total bilirubin (TB), as well as lipid profiles, were determined. Histopathological examination of the liver tissues was also conducted to confirm the findings of biochemical analysis. …”
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2705
Nitrogen, Phosphorus, and Potassium Requirements to Improve <i>Portulaca oleracea</i> L. Growth, Nutrient and Water Use Efficiency in Hydroponics
Published 2025-01-01“…The recommended levels of P and K mirrored low levels in lipid peroxidation, mainly due to the increase in catalase enzymatic activity. …”
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2706
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2707
Transcriptomic characterization of the functional and morphological development of the rumen wall in weaned lambs fed a diet containing yeast co-cultures of Saccharomyces cerevisia...
Published 2025-01-01“…Ultimately, these results suggest that dietary supplementation with NM has driven the degradation of fatty acids, the induction of oxidative phosphorylation, the acceleration of lipid metabolism, the production of ATP to sustain ruminal growth, and the maintenance of intracellular NADH/NAD+ homeostasis on weaned lambs and is superior to single yeast fermentation.DiscussionThese results thus offer a theoretical foundation for further studies examining the mechanisms through which NM cultures can influence ruminal development in lambs.…”
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2708
Fracture-healing effects of Rhizoma Musae ethanolic extract: An integrated study using UHPLC-Q-Exactive-MS/MS, network pharmacology, and molecular docking.
Published 2025-01-01“…KEGG analysis suggested that EERM's mechanism may involve signaling pathways such as PI3K-Akt, lipid and atherosclerosis, EGFR tyrosine kinase inhibitor resistance, and MAPK pathways. …”
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2709
Rosuvastatin effects on the HDL proteome in hyperlipidemic patients
Published 2023-09-01“…Sixty-nine HDL proteins were identified, belonging to four main biological function clusters: lipid transport and metabolism; platelet activation, degranulation, and aggregation, wound response and wound healing; immune response; inflammatory and acute phase response. …”
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2710
The modulating effect of coat color mutations on the generation and neutralization of reactive oxygen species in the Аmerican mink (Neovison vison) as a model
Published 2015-07-01“…The direcessive sapphire (a/a р/р) combination induced high levels of antioxidant enzymes’ activities as well as of thiobarbituric acid-reactive products (TBА-RPs), characterizing lipid peroxidation level. In heart tissue, coat color mutations exerted modulating effects on both RO S generation and the level of low-molecular-weight antioxidants. …”
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2711
INVESTIGATING THE BIOCHEMICAL PROFILE AND NUTRITIONAL COMPOSITION OF VERNONIA AMYGDALINA LEAVES: A STUDY ON ANTIOXIDANT PROPERTIES, PHYTOCHEMICAL COMPOSITION, ENZYME INHIBITION, AN...
Published 2024-05-01“…The extract also demonstrated a significant 49.01% inhibition of lipid peroxidation, highlighting its potential in mitigating oxidative stress. …”
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2712
Combined effect of healthy lifestyles and obesity on cardiometabolic risks in Chinese rural adults
Published 2025-01-01“…Body mass index (BMI), waist circumference (WC), blood pressure, blood lipid, and fasting blood glucose were measured. Logistic models were applied to assess the combined associations of healthy lifestyles and obesity with cardiometabolic risks. …”
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2713
Life Stage‐ and Sex‐Specific Sensitivity to Nutritional Stress in a Holometabolous Insect
Published 2025-01-01“…Individuals starved as larvae had similar carbohydrate and lipid (i.e., fatty acid) contents as non‐starved individuals, potentially due to building up energy reserves during development, while starvation during adulthood or at both stages led to reduced energy reserves in males. …”
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2714
Proximate, Mineral Contents and Physicochemical Properties of <i>Chrysophyllum Albidum</i> (African Star Apple) Kernel Flour and Oil
Published 2019-08-01“…The results obtained from the Proximate Analysis shows the kernel has a moisture content of 10.06±0.08 %, Ash content of 2.72±007 %, Crude lipid of 13.31±008 %, Crude Protein of 7.92±0.00 %, Crude Fibre of 1.59±0.00 % and Carbohydrate of 65.41±0.05 %. …”
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2715
Genome-wide association study of the fatty liver index in the Taiwanese population reveals shared and population-specific genetic risk factors across ethnicities
Published 2025-02-01“…Pathway analysis of GWAS significant genes revealed that lipid metabolism and the peroxisome proliferator-activated receptor (PPAR) signaling pathway are causes of hepatic fat accumulation. …”
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2716
DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis
Published 2021-01-01“…Diacylglycerol O-acyltransferase 1 (DGAT1) can synthesize triglycerides by transferring acyl-CoA to diacylglycerol, which plays a key role in lipid synthesis. However, the role of DGAT1 in ovarian cancer is not yet elucidated. …”
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2717
Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification
Published 2022-01-01“…Our results indicated that quercetin, as the main active component in AMB, exerts an anti-NAFLD effect by regulating the AMPK/MAPK/TNF-α and AMPK/ACC/CPT1α signaling pathways to inhibit inflammation and alleviate lipid accumulation.…”
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2718
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis
Published 2022-01-01“…Increased generation of lipid peroxidation products (ROS and MDA) and decreased activities of antioxidant enzymes (SOD and CAT) suggested an aberrant oxidative stress status in EAP model. …”
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2719
The Nutritional Composition of Maca in Hypocotyls (Lepidium meyenii Walp.) Cultivated in Different Regions of China
Published 2017-01-01“…The essential amino acids (EAA) contents ranged from 189.19 to 312.90 mg/g protein. The crude lipid content of different maca ranged from 0.59% to 1.00% and has no significant difference (P>0.05). …”
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2720
Triglyceride-glucose index in predicting the risk of new-onset diabetes in the general population aged 45 years and older: a national prospective cohort study
Published 2025-01-01“…Improving insulin resistance by regulating glucose and lipid metabolism plays an important role in the primary prevention of diabetes.…”
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