Reproductive Cycle of Marphysa sanguinea (Montagu, 1815) (Polychaeta: Eunicidae) in the Lagoon of Tunis by Monia El Barhoumi, Patrick Scaps, Fathia Zghal

“…The cytoplasmic material of the mature oocytes (diameter superior to 200 μm) is asymmetrically distributed; large lipid droplets and large yolk spheres occupy the vegetal pole of the oocyte while smaller yolk spheres are situated in the animal hemisphere. …”
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Mycobacterium avium Infection of Multinucleated Giant Cells Reveals Association of Bacterial Survival to Autophagy and Cholesterol Utilization by Jayanthi J. Joseph, Amy Leestemaker-Palmer, Soheila Kazemi, Lia Danelishvili, Luiz E. Bermudez

“…Characterization of MGCs with transmission electron microscopy revealed an accumulation of cytoplasmic lipid droplets, autophagic activity, and multiple nuclei. …”
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Molecular Mechanism of Stem Cell Differentiation into Adipocytes and Adipocyte Differentiation of Malignant Tumor by Kexin Zhang, Xudong Yang, Qi Zhao, Zugui Li, Fangmei Fu, Hao Zhang, Minying Zheng, Shiwu Zhang

“…During this process, the preadipocytes cease to proliferate, begin to accumulate lipid droplets, and develop morphologic and biochemical characteristics of mature adipocytes. …”
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Exploring salinity induced adaptations in marine diatoms using advanced photonic techniques by Julijana Cvjetinovic, Yekaterina D. Bedoshvili, Nickolai A. Davidovich, Eugene G. Maksimov, Ekaterina S. Prikhozhdenko, Daria A. Todorenko, Daria V. Bodunova, Olga I. Davidovich, Igor S. Sergeev, Dmitry A. Gorin

“…At 60‰ salinity, anomalies are observed in the development of silica valves and polysaccharide layers, suggesting abnormalities in valve morphogenesis. Lipid droplets within the cells display a minimum diameter at 40‰, indicating metabolic adjustments to osmotic stress. …”
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Elaidic acid leads to mitochondrial dysfunction via mitochondria-associated membranes triggers disruption of mitochondrial calcium fluxes by Hui Liu, Xuenan Li, Ziyue Wang, Lu Li, Yucai Li, Haiyang Yan, Yuan Yuan

“…Swelling of the inner mitochondrial cristae and mitochondrial vacuolization occurred, with a marked increase in lipid droplets.…”
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Caffeic Acid Phenethyl Ester Regulates PPAR’s Levels in Stem Cells-Derived Adipocytes by Luca Vanella, Daniele Tibullo, Justyna Godos, Francesca Romana Pluchinotta, Claudia Di Giacomo, Valeria Sorrenti, Rosaria Acquaviva, Alessandra Russo, Giovanni Li Volti, Ignazio Barbagallo

“…Quantification of Oil Red O-stained cells showed that lipid droplets decreased following Cape treatment as well as radical oxygen species formation. …”
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Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity by Komal Sodhi, Jordan Hilgefort, George Banks, Chelsea Gilliam, Sarah Stevens, Hayden A. Ansinelli, Morghan Getty, Nader G. Abraham, Joseph I. Shapiro, Zeid Khitan

“…Uric acid increased adipogenesis by increasing NADPH oxidase expression and elevation in the adipogenesis markers C/EBPα, PPARγ, and Mest, while decreasing small lipid droplets and Wnt10b levels. We treated MSCs with fructose, a fuel source that increases uric acid levels. …”
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Quorum sensing-mediated inter-specific conidial anastomosis tube fusion between Colletotrichum gloeosporioides and C. siamense by Nikita Mehta, Abhishek Baghela

“…Movement of nuclei, mitochondria, and lipid droplets were observed during the CAT fusion. Post CAT fusion, the resulting conidia gave rise to putative heterokaryotic progenies with variable colony characteristics as compared to their parental strains. …”
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Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an essential regulator of Rab2 in the secretory pathway. by Justin J Quan, Lachezar A Nikolov, Jihui Sha, James A Wohlschlegel, Isabelle Coppens, Peter J Bradley

“…TgTBC9 knockdown also results in the formation of large lipid droplets (LDs) and multi-membranous structures surrounded by ER membranes, further indicating a disruption of ER functions. …”
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Adipose-Derived Stromal Cells Attenuate Adipose Inflammation in Obesity through Adipocyte Browning and Polarization of M2 Macrophages by Wen-Chao Zhang, Feng Qin, Xiao-Jun Wang, Zhi-Fei Liu, Lin Zhu, Ang Zeng, Ming-Zi Zhang, Nan-Ze Yu, Xiao Long

“…Furthermore, the multilocular lipid droplets located in the center was increased in differentiated brown adipocytes, and brown fat-associated proteins, UCP1, PPAR-γ, and LPL were highly expressed in brown adipocytes differentiated from ADSCs. …”
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The Expression of Thymic AQP7 and Perilipin 1 (PLIN1) in Rats Fed a High-Fructose Diet is Modified by Voluntary Physical Activity by Jülide Tozkır, Nihayet Fırat, Ebru Göncü, Onur Ersoy, Pınar Tayfur, Orkide Palabıyık

“…Perilipin 1 (PLIN1) regulates lipolysis on the surface of lipid droplets in adipocytes and promotes the transport of glycerol out of the cell via AQP7. …”
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Bisphenol S Induces Lipid Metabolism Disorders in HepG2 and SK-Hep-1 Cells via Oxidative Stress by Kai-Xing Lin, Zi-Yao Wu, Mei-Lin Qin, Huai-Cai Zeng

“…The results indicated that BPS could inhibit the mRNA expression of PPARα and carnitine palmitoyl transferase 1B (CPT1B), reduce lipid metabolism, promote mRNA or protein expression of SREBP1C and fatty acid synthase (FASN), and increase lipid synthesis. Increased lipid droplets were observed using morphological Oil Red O staining. …”
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Effects of Low or High Dosages of Dietary Sodium Butyrate on the Growth and Health of the Liver and Intestine of Largemouth Bass, Micropterus salmoides by Yiyang Ge, Shibin Yao, Ye Shi, Chunfang Cai, Chengrui Wang, Ping Wu, Xiamin Cao, Yuantu Ye

“…The size of hepatocytes was enlarged, and the intracellular lipid droplets and the degree of hepatic fibrosis were increased in the SB20 group compared to the CON group. …”
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Impact of sleep deprivation on colon cancer: Unraveling the KynA-P4HA2-HIF-1α axis in tumor lipid metabolism and metastasis by Zuojie Peng, Jia Song, Wenzhong Zhu, Haijun Bao, Yuan Hu, Yongping Shi, Xukai Cheng, Mi Jiang, Feifei Fang, Jinhuang Chen, Xiaogang Shu

“…Conclusions: Our findings reveal that sleep deprivation impairs intracellular lipolysis by KynA, leading to lipid droplets accumulation in colon cancer cells. This process ultimately promotes colon cancer liver metastasis. …”
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Sodium alginate ameliorates health in freshwater fish through gut-liver axis modulation under high carbohydrate diets by Wenlu Zhu, Huilin Zhang, Haitao Pan, Hao Zeng, Wenjun Wang, Yunfeng Liu, Zirui Wang, Qiubai Zhou, Chuanqi Yu

“…Then our outcomes evinced that LA improves various health-related parameters, including reduction of hepatosomatic index (HSI), serum glucose, triglycerides, and aminotransferase levels, as well as the decrease in hepatic lipid droplets, glycogen, and collagen fiber content. …”
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Myocardin-Related Transcription Factor A (MRTF-A) Regulates the Balance between Adipogenesis and Osteogenesis of Human Adipose Stem Cells by Laura Hyväri, Sari Vanhatupa, Heidi T. Halonen, Minna Kääriäinen, Susanna Miettinen

“…Our results of image-based quantification of Oil Red O stained lipid droplets and perilipin 1 staining denote that MRTF-A inhibition enhanced the adipogenic differentiation. …”
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Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis by Prabhakar Yellanur Konda, Vijayakumar Poondla, Krishna Kumar Jaiswal, Sreenivasulu Dasari, Reddemma Uyyala, Venkata Prasad Surtineni, Janardhan Yadav Egi, Anthony Johnson Antony Masilamani, Lakshmi Bestha, Sreenath Konanki, Muthukumaran Muthulingam, Lakshman Kumar Lingamgunta, Bindu Prasuna Aloor, Sridevi Tirumalaraju, Ankanna Sade, Venkata Ratnam Kamsala, Sreeharsha Nagaraja, Ranjani Ramakrishnan, Vijayakumar Natesan

“…Reduction (p < 0.05) in insulin resistance (5.20 ± 0.03), lipid profile (TC 120 ± 0.05; TG 160 ± 0.24; HDL 38 ± 0.03), liver lipid peroxidation (0.7 ± 0.01), hepatic enzyme markers (AST 82 ± 0.06; ALT 78 ± 0.34; ALP 42 ± 0.22), and hepatic steatosis by increasing liver antioxidant potential (CAT 1.4 ± 0.30; GSH 1.04 ± 0.04; SOD 0.82 ± 0.22) with normal hepatic triglycerides (15 ± 0.02) and glycogen (0.022 ± 0.15) contents and also showed normal liver size, less accumulation of lipid droplets with only a few congestion. It is concluded that the increased intestinal S. cerevisiae yeast can switch anti-obesity, antidiabetic, antioxidative stress, antioxidant and anti-hepatosteatosis effect. …”
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The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism by Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi

“…Results Doxycycline‐treated GSDMD‐NTki/wt × Alb‐creki/wt mice showed severe liver damage, vacuolation of hepatocytes, increased collagen fibers, and accumulation of lipid droplets. The expression of liver fibrosis related genes was greatly increased in the doxycycline‐treated mouse liver compared with untreated mouse liver. …”
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TMEM135 deficiency improves hepatic steatosis by suppressing CD36 in a SIRT1-dependent manner by Arun Chhetri, Channy Park, Hyunsoo Kim, Laxman Manandhar, Chagtsalmaa Chuluunbaatar, Jaetaek Hwang, Xiaofan Wei, Gyuho Jang, Batching Chinbold, Hyug Moo Kwon, Sang-wook Lee, Raekil Park

“…TMEM135-depleted primary hepatocytes and AML12 cells exhibited less lipid accumulation when treated with FFA compared to control cells, as shown as lipid droplets. Consistently, the effect of TMEM135 depletion on lipid accumulation was completely reversed under TMEM135 overexpression conditions. …”
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Molecular genetic and morphological characteristics of Micractinium thermotolerans and M. inermum (Trebouxiophyceae, Chlorophyta) from pyroclastic deposits of the Kamchatka Peninsu... by R. Z. Sushchenko, V. Yu. Nikulin, V. B. Bagmet, A. Yu. Nikulin

“…In addition, cells with colorless lipid droplets were detected in aging cultures of both species. …”
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