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1621
Coordinated Actions of FXR and LXR in Metabolism: From Pathogenesis to Pharmacological Targets for Type 2 Diabetes
Published 2014-01-01“…Here we review the recent progress concerning the physiological and pathophysiological roles of FXRs and LXRs in the regulation of bile acid, lipid and glucose metabolism and the implications in T2D, taking into account that these two nuclear receptors are potential pharmaceutical targets for the treatment of T2D and its complications.…”
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1622
Investigation of Antioxidant and Hepatoprotective Activity of Standardized Curcuma xanthorrhiza Rhizome in Carbon Tetrachloride-Induced Hepatic Damaged Rats
Published 2014-01-01“…In the case of hepatoprotective activity, CX hexane fraction showed significant improvement in terms of a biochemical liver function, antioxidative liver enzymes, and lipid peroxidation activity. Good recovery was observed in the treated hepatic tissues histologically. …”
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1623
Application of Pomegranate Peel Extract, a Waste Agricultural Product, as a Natural Preservative in Tahini
Published 2023-01-01“…The concentrations 1 and 2% act better to inhibit lipid peroxidation. Overall, the general acceptance of samples containing 1 and 2% PPE was recorded better than other samples. …”
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1624
Naringenin induces ferroptosis in osteosarcoma cells through the STAT3-MGST2 signaling pathway
Published 2025-02-01“…Ferroptosis is a novel form of regulated cell death induced by excessive iron accumulation, leading to lipid peroxidation that results in cellular dysfunction and death. …”
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1625
New Insights into Chemical Profiles and Health-Promoting Effects of Edible Mushroom <i>Dictyophora indusiate</i> (Vent ex. Pers.) Fischer: A Review
Published 2025-01-01“…Mushrooms help regulate metabolism and improve lipid profiles, with potential applications in managing metabolic disorders, cancer, cardiovascular diseases, diabetes, and neurodegenerative conditions. …”
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1626
Plaque morphological changes after drug-coated balloon angioplasty according to underlying plaque components
Published 2025-02-01“…The plaque volume of the lipid pool was not changed at follow-up compared with that just after DCB dilation. …”
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1627
The Roles of PPARs in the Fetal Origins of Metabolic Health and Disease
Published 2008-01-01“…These findings suggest that two separate PPAR-dependent mechanisms may be involved in the fetal adaptations to the maternal diet, one, mediated by PPAR-γ and PPAR-β/δ, regulating cell growth and differentiation; and another adapting long-term lipid metabolism via epigenetic changes in PPAR-α to optimise postnatal survival.…”
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1628
Microvascular angina in postmenopausal women.
Published 2011-10-01“…These women were tested for lipid profile. Endothelial function was measured in the brachial artery by ultrasound, and a 24 hours (Holter) lectrocardiographic study. …”
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1629
Targeting ferroptosis: a promising approach for treating lung carcinoma
Published 2025-01-01“…Ferroptosis, a distinct pattern of cell death marked by the buildup of iron-dependent lipid peroxides, has been shown to be a novel and potentially more effective treatment for lung carcinoma. …”
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1630
Ultraviolet Spectrophotometric Method for Determination of Glipizide in Presence of Liposomal/Proliposomal Turbidity
Published 2013-01-01“…A simple and sensitive ultraviolet spectrophotometric method for quantitative estimation of glipizide in presence of lipid turbidity is described to avoid false estimation due to diffraction by turbidity. …”
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1631
In vitro evaluation of stearylamine cationic nanoemulsions for improved ocular drug delivery
Published 2019-12-01“…The aim of this study was to develop a cationic ophthalmic NE with cationic lipid stearylamine (SA) as a carrier of a positive charge. …”
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1632
Phytosomes – an Effective Drug-Delivery System. Development, Technology, Application.
Published 2024-12-01“…A review of various studies on the production and application of phytosomal medical forms, which are in the form of hybrid molecules with high solubility in lipid and aqueous environments, is presented in this article. …”
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1633
Comparative Evaluation of the Antidiabetic Effects of Different Parts of Cassia fistula Linn, a Southeast Asian Plant
Published 2013-01-01“…Biochemical parameters like blood glucose, insulin, glycosylated hemoglobin, lipid profile, and serum marker enzymes were determined. …”
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1634
Recent advances in small molecule LpxC inhibitors against gram-negative bacteria (2014–2024)
Published 2025-02-01“…Uridine diphosphate-3-O-(hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) is a metalloenzyme cofactored with zinc ions, which is a key enzyme in the synthesis of outer membrane lipid A in Gram negative bacteria. LpxC is highly conserved and homologous among different Gram-negative bacteria, which makes LpxC a promising target against multidrug-resistant Gram-negative bacteria. …”
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1635
Oxidative Stress: An Effective Prognostic Tool for an Early Detection of Cardiovascular Disease in Menopausal Women
Published 2016-01-01“…They were screened for lipid profile, serum malondialdehyde (MDA), serum LDL carbonyl protein, and serum superoxide dismutase (SOD). …”
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1636
Protective Effect of Thyme Extract on Albino Rats Exposed to Paraquat
Published 2022-01-01“…Therefore, the current results indicate that, the herbicide PQ showed adverse effects through initiation of lipid peroxidation, while T.vulgaris extract produced a significant recovery in ameliorating some aspects of PQ toxicity. …”
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1637
Protective Effect of Thyme Extract on Albino Rats Exposed to Paraquat
Published 2022-01-01“…Therefore, the current results indicate that, the herbicide PQ showed adverse effects through initiation of lipid peroxidation, while T.vulgaris extract produced a significant recovery in ameliorating some aspects of PQ toxicity. …”
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1638
Exploring the effects of perfluorooctanoic acid (PFOA) and tetrabromobisphenol A (TBBP-A) on silkworm from the insights of metabolome
Published 2025-01-01“…Exposure to these chemicals significantly altered metabolic profiles, leading to disruptions in pathways related to lipid, carbohydrate, and amino acid metabolism. These findings suggest that PFOA and TBBP-A disrupt crucial metabolic processes in silkworms, indicating potential toxicity and prompting further investigation into their effects on human health and the environment. …”
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1639
Expression of protein phosphatase 4 in different tissues under hypoxia
Published 2023-07-01“…Protein phosphatase 4 (PP4) has been found as a new factor in the regulation of sugar and lipid metabolism. Here, we investigate the differential expression of PP4 at a simulated altitude of 4,500 m in the heart, lung, and brain tissues of rats. …”
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1640
Psychobiotic effects of probiotics and prebiotics
Published 2018-08-01“…Intestinal microbiome is a factor of hypothalamic-pituitary-adrenal axis formation that is involved in regulation of immunomodulation, lipid metabolism, energy balance and electrophysiologic activity of enteric nervous system. …”
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