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1301
Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic SteatosisSummary
Published 2025-01-01“…Mitochondrial function and mitochondria-ER interaction (MAM) relevant to ALR-Kcr modification was evaluated for hepatocyte lipid metabolism both in in vivo and in vitro experiments. …”
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1302
The Effect of Diacerein on Type 2 Diabetic Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis
Published 2020-01-01“…Secondary outcomes were glycosylated hemoglobin A1c (HbA1c), body mass index (BMI), lipid profiles, hematological indexes including hematocrit and platelet count, and systematic inflammatory level expressed as a C-reactive protein (CRP) level. …”
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1303
Differentiation Potential of Pancreatic Fibroblastoid Cells/Stellate Cells: Effects of Peroxisome Proliferator-Activated Receptor Gamma Ligands
Published 2011-01-01“…Cells treated with ciglitazone for three days showed enhanced lipid content and induction of proteins involved in lipid metabolism. …”
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1304
The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic dysfunction-associated steatotic liver disease
Published 2025-01-01“…Anthropometric parameters, demographic information, and serum biochemical variables—including glycemic parameters, lipid profiles, liver enzymes, and Sirt-1 levels—were assessed. …”
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1305
Age- and Gender-Related Differences in LDL-Cholesterol Management in Outpatients with Type 2 Diabetes Mellitus
Published 2015-01-01“…Women were older and more obese, with longer diabetes duration, higher total-cholesterol, LDL-C, and HDL-C serum levels compared to men (P<0.0001). Lipid profile was monitored in ~75% of subjects, women being monitored less frequently than men, irrespective of age. …”
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1306
Liver GlucokinaseA456V Induces Potent Hypoglycemia without Dyslipidemia through a Paradoxical Induction of the Catalytic Subunit of Glucose-6-Phosphatase
Published 2011-01-01“…Recent reports point out the importance of the complex GK-GKRP in controlling glucose and lipid homeostasis. Several GK mutations affect GKRP binding, resulting in permanent activation of the enzyme. …”
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1307
Clinical Predictors of Aspirin Resistance in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Published 2025-01-01“…These findings imply that assessing lipid and glucose regulation could enhance the development of personalized preventive approaches for vascular complications linked to diabetes. …”
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1308
Oxidative Stability of the Meat of Broilers Fed Diets Supplemented with Various Levels of Blackcurrant Extract (Ribes nigrum L.) during Different Time Period
Published 2018-01-01“…Significant extent of lipid oxidation process was found in 1-d-chilled pectoral muscles of chickens receiving BC diet for 20 d or diet containing 2.5 g/kg of the extract. …”
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1309
Foliar application of nano biochar solution elevates tomato productivity by counteracting the effect of salt stress insights into morphological physiological and biochemical indice...
Published 2025-01-01“…Overall, NBS foliar application significantly improved all growth and yield indices, pigments, primary and secondary metabolites, leaf water content, antioxidant enzyme activities as well as reduced electrolyte leakage and lipid peroxidation rates in tomato to combat stress conditions. …”
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1310
Differential Immunogenicity and Protective Efficacy Elicited by MTO- and DMT-Adjuvanted CMFO Subunit Vaccines against Mycobacterium tuberculosis Infection
Published 2020-01-01“…In this study, we compared the immunogenicity and protective efficacy of CMFO subunit vaccines against primary progressive TB in two different adjuvant systems: the MTO oil-in-water (O/W) emulsion composed of monophosphoryl lipid A (MPL), trehalose-6,60-dibehenate (TDB), and oil in water emulsion MF59 and the DMT liposome containing dimethyldioctadecylammonium bromide (DDA), monophosphoryl lipid A (MPL), and trehalose-6,60-dibehenate (TDB). …”
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1311
Dyslipidemia rather than Type 2 Diabetes Mellitus or Chronic Periodontitis Affects the Systemic Expression of Pro- and Anti-Inflammatory Genes
Published 2017-01-01“…Anti-inflammatory genes, such as IL10, positively correlated with parameters of glucose, lipid, and periodontal profiles, while proinflammatory genes, such as IFNG, were negatively correlated with these parameters. …”
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1312
Ferroptosis Is a Potential Therapeutic Target for Pulmonary Infectious Diseases
Published 2023-01-01“…Ferroptosis is a new type of iron-dependent cell death caused by lipid peroxide (LPO) accumulation and involved in disease of pulmonary infection. …”
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1313
Signal Transduction of Sphingosine-1-Phosphate G Protein—Coupled Receptors
Published 2006-01-01“…Sphingosine-1-phosphate (S1P) is a bioactive lipid capable of eliciting dramatic effects in a variety of cell types. …”
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1314
PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia
Published 2017-01-01“…PPAR-γ plays roles in lipid homeostasis, sebocyte maturation, and peroxisome biogenesis and has shown anti-inflammatory effects. …”
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1315
Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation
Published 2012-01-01“…Molecular studies will add significantly to the concept of these flavonoids as viable and promising therapeutic agents to treat the dysregulation of lipid homeostasis, metabolic disease, and its cardiovascular complications.…”
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1316
Cytokine-Leukotriene Receptor Interactions
Published 2007-01-01“…A privileged interaction exists between these lipid mediators and another group of molecules essential for inflammation and immune modulation, namely, cytokines. …”
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1317
Mitochondrial Dynamics: Functional Link with Apoptosis
Published 2012-01-01“…Mitochondria participate in a variety of physiologic processes, such as ATP production, lipid metabolism, iron-sulfur cluster biogenesis, and calcium buffering. …”
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1318
The Role of PPARα Activation in Liver and Muscle
Published 2010-01-01“…It is a sensor for changes in levels of fatty acids and their derivatives that responds to ligand binding with PPAR target gene transcription, inasmuch as it can influence physiological homeostasis, including lipid and carbohydrate metabolism in various tissues. …”
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1319
Receptor mechanisms of PAF mediated lymphatic constriction in the canine forelimb
Published 1992-01-01“…Platelet activating factor (PAF) is a potent inflammatory lipid. In this study we assessed the ability of PAF to impact lymphatic vessel function by altering prenodal lymphatic resistance. …”
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1320
Progressive Dyspnea in a 40-Year-Old Man Caused by Giant Mediastinal Thymolipoma
Published 2016-01-01“…Clinical evaluation revealed a giant mass of lipid density filling almost the entire left hemithorax with mediastinal shift. …”
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