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2381
Adipocyte DIO2 Expression Increases in Human Obesity but Is Not Related to Systemic Insulin Sensitivity
Published 2018-01-01“…T3 not only stimulates adaptive thermogenesis but also affects adipose tissue (AT) lipid accumulation, mitochondrial function, inflammation, and potentially systemic metabolism. …”
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2382
Anticancer Potential of Green Synthesized Silver Nanoparticles Using Extract of Nepeta deflersiana against Human Cervical Cancer Cells (HeLA)
Published 2018-01-01“…Furthermore, the results also showed a significant increase in ROS and lipid peroxidation (LPO), along with a decrease in MMP and glutathione (GSH) levels. …”
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2383
Decoding the trajectory of antibiotic resistance genes in saline and alkaline soils: Insights from different fertilization regimes
Published 2025-01-01“…Meta-genomic and Meta-transcriptomic analysis consistently demonstrated bacterial antibiotic resistance was primarily associated with pyruvate, energy and lipid metabolic pathways. The functional gene related to salinity and alkalinity, like cysH, cysK, plsB and plsC showed negative correlations with MDR. …”
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2384
The Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Pan-Cancer
Published 2020-01-01“…The functions of the PPAR family (PPARA, PPARD, and PPARG) and their coactivators (PPARGC1A and PPARGC1B) in maintenance of lipid and glucose homeostasis have been unveiled. …”
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2385
Microencapsulated Escape Lysine with Tannin as an Adjuvant in Sheep Diets
Published 2025-01-01“…This study hypothesized that wax lipid matrices are effective encapsulants for escape lysine in ruminants and tested tannin extract as an adjuvant. …”
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2386
CircBAZ1B stimulates myocardial ischemia/reperfusion injury (MI/RI) by modulating miR-1252-5p/ATF3-mediated ferroptosis
Published 2024-05-01“…Cell viability, apoptosis, lipid reactive oxygen species (ROS) levels and iron content were determined via Cell Counting Kit-8 (CCK-8) and flow cytometric assays. …”
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2387
Single-cell transcriptomes of dissecting the intra-tumoral heterogeneity of breast cancer microenvironment
Published 2024-12-01“…In macrophages, two mainly tumor associated macrophages (TAMs), TAM1 and TAM2, were also detected and the highly variable genes in TAM2 were strongly enriched in IFN-α and IFN-γ. The changes of lipid metabolism pathways in macrophages are closely related to the microenvironment of breast cancer. …”
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2388
Epidemiologic features of non-alcoholic fatty liver disease in Russia
Published 2014-10-01“…Investigation included general (anthopometrical), laboratory and instrumental investigations, such as assessment of hepatites B and C markers, liver transaminases, gamma-glutamyltranspeptidase, blood lipid spectrum, glucose level, and abdominal ultrasound investigation, if required — esophagogastroduodenoscopy. …”
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2389
IDO1 inhibits ferroptosis by regulating FTO-mediated m6A methylation and SLC7A11 mRNA stability during glioblastoma progression
Published 2025-01-01“…IDO1 overexpression suppressed ferroptotic cell death, reduced ROS and lipid peroxide generation in GBM cells. IDO1 expression increased the SLC7A11 mRNA stability through FTO-dependent m6A methylation. …”
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2390
Exploring <i>RNF213</i> in Ischemic Stroke and Moyamoya Disease: From Cellular Models to Clinical Insights
Published 2024-12-01“…This gene encodes an E3 ubiquitin ligase with diverse roles in angiogenesis, vascular remodeling, lipid metabolism, and cerebral blood flow regulation, yet its exact mechanisms in cerebrovascular pathology remain incompletely understood. …”
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2391
Natural History of Metabolic Dysfunction-Associated Steatotic Liver Disease: From Metabolic Syndrome to Hepatocellular Carcinoma
Published 2025-01-01“…<i>Introduction</i>: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) stems from disrupted lipid metabolism in the liver, often linked to obesity, type 2 diabetes, and dyslipidemia. …”
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2392
Functional effects of natural silicate, yeast and saponins based product on the growth and health status of the Pacific white shrimp Litopenaeus vannamei
Published 2022-05-01“…Four isonitrogenous and iso-lipidic experimental diets were formulated to contain 0%, 0.3% NSY, 0.2% SBP and 0.6% NSY. …”
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2393
Brincidofovir Use after Foscarnet Crystal Nephropathy in a Kidney Transplant Recipient with Multiresistant Cytomegalovirus Infection
Published 2017-01-01“…Despite a large decrease in immunosuppression, CMV disease was not controlled and a salvage therapy with Brincidofovir (BCV), which is an oral lipid conjugate of cidofovir with limited nephrotoxicity, was attempted. …”
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2394
Cupric Doping Hollow Prussian Blue Nanoplatform for Enhanced Cholesterol Depletion: a Promising Strategy for Breast Cancer Therapy and Metastasis Inhibition
Published 2025-01-01“…Tumor‐responsive released Cu2+ notably augments ChOx activity, facilitating cholesterol depletion and disrupting lipid rafts, thereby impeding cell invasion and migration. …”
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2395
Azospirillum brasilense and organomineral fertilizer co-inoculated with Bradyrhizobium japonicumon oxidative stress in soybean
Published 2022-06-01“…Plant protection to stresses happened mainly by reductions in the superoxide dismutase activity, lipid peroxidation, and hydrogen peroxide concentration. …”
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2396
Intravenous Infusion of Dexmedetomidine Combined Isoflurane Inhalation Reduces Oxidative Stress and Potentiates Hypoxia Pulmonary Vasoconstriction during One-Lung Ventilation in Pa...
Published 2015-01-01“…Administration of Dex significantly reduced Qs/Qt and increased PaO2 after OLV, accompanied with reduced lipid peroxidation product malondialdehyde and higher levels of SOD activity as well as serum NO (all P<0.05 DISO versus NISO). …”
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2397
Real-World HbA1c Changes Among Type 2 Diabetes Mellitus Patients Initiating Treatment With a 1.0 Mg Weekly Dose of Semaglutide for Diabetes
Published 2024-11-01“…The majority of patients had lipid metabolism disorder (90.8%), hypertension (86.6%), diabetes with complications (86.8%), or other nutritional/endocrine/metabolic disorders (72.5%). …”
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2398
Proteome‐Wide Mendelian Randomization Identifies Therapeutic Targets for Abdominal Aortic Aneurysm
Published 2025-02-01“…Several causal proteins are involved in pathways regulating lipid metabolism, immune responses, and extracellular matrix organization. …”
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2399
Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity
Published 2019-01-01“…This could be due to impaired lipid metabolism in muscle cells.…”
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2400
Oxidative impact on lipoprotein structure: Insights from dynamic light scattering
Published 2025-03-01“…Lipoproteins, key biomolecules in lipid transport, are particularly susceptible to oxidative modifications, which can contribute to atherogenesis. …”
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