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2301
Histological, physiological and transcriptomic analysis in hepatopancreas of Procambarus clarkii under heat stress
Published 2025-01-01“…Heat stress notably altered the expression of genes related to glucose, lipid, and protein metabolism, as well as oxidative phosphorylation pathways. …”
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2302
Biomarkers of racism-based stress injury: A feasibility and correlation study
Published 2025-01-01“…Elevated EDS scores were associated with adverse lipid profiles, including higher cholesterol/high-density lipoprotein (HDL) ratios and lower HDL levels, as well as elevated inflammatory markers (NF-kB activity) and reduced antiviral response (interferon response factor). …”
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2303
Correlation between MDA Level and Chitotriosidase-1 Activity in Seminal Fluid of Iraqi Infertile Males
Published 2024-12-01“…On the other hand, malondialdehyde is a marker of lipid peroxidation, reflecting oxidative stress levels. …”
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2304
Protective Role of Picralima nitida Seed Extract in High-Fat High-Fructose-Fed Rats
Published 2020-01-01“…Anthropometric and antioxidant parameters, lipid profile, plasma glucose, and insulin levels and the relative expression of some metabolic genes were assessed. …”
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2305
The Function of Two <i>Brassica napus</i> β-Ketoacyl-CoA Synthases on the Fatty Acid Composition
Published 2025-01-01“…Various types of fatty acid products are used to build lipid molecules, such as oils, suberin, wax, and membrane lipids. …”
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2306
Effect of High-Fat Diet on Spatial Learning and Memory and Regulatory Role of N-Methyl-D-Aspartate Receptors in the Dentate Gyrus
Published 2024-12-01“…Newly weaned rats were fed with high-fat diet (HFD) (containing 45% fat) for 12 weeks, and body mass, serum lipid and glucose levels were observed. The Morris water maze (MWM) test was used to evaluate the spatial learning and memory capacity of the rats; Western blot was used to detect the expression of phosphorylated Ca2+/calmodulin dependent protein kinase II (p-CaMKII) and cAMP-response element binding protein (p-CREB), pro-inflammatory cytokines, including interleukin-6 (IL-6) and IL-1β in the hippocampal dentate gyrus (DG); the expression of ionized calcium binding adapter molecule 1 (Iba1) in the DG were observed by Western blot and immunohistochemistry. …”
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2307
M2 Macrophages as a Potential Target for Antiatherosclerosis Treatment
Published 2019-01-01“…Optimal medical treatments for atherosclerotic risk factors with current antihypertensive and lipid-lowering drugs (for example, statins) are widely used in clinical practice. …”
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2308
Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Af...
Published 2018-01-01“…Upon palmitic acid stimulation, intracellular contents of lipids, as well as the expression and activity of three key molecules in thyroid hormone synthesis (i.e., thyroglobulin, sodium iodide symporter, and thyroperoxidase), were determined in human primary thyrocytes. …”
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2309
Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Me2DO2A on Experimental Articular Pain in Rats
Published 2013-01-01“…MnL4 (10−7 M) prevented the lipid peroxidation of isolated human chondrocytes when was produced by RAW 264.7. …”
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2310
Cryoimmobilized anther analysis reveals new ultrastructural insights into Rhynchospora (Cyperaceae) asymmetrical microsporogenesis
Published 2025-01-01“…Microtubules attach to centromeres located deep within holocentric chromosomes, while extensive cytoplasmic connections facilitate material exchange until callose deposition encloses meiocytes. Lipid distribution contributes to cell asymmetry, resulting in the characteristic asymmetric tetrads. …”
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2311
Comparison of the Efficiency of Lepidium sativum, Ficus carica, and Punica granatum Methanolic Extracts in Relieving Hyperglycemia and Hyperlipidemia of Streptozotocin-Induced Diab...
Published 2021-01-01“…Oral administration of F. carica and L. sativum extracts at the dosage of 100 and 200 mg/kg significantly reduced glucose, lipid profile, kidney, and liver enzyme levels. A significant increase in HbAlc levels was also observed with L. sativum extract at a dose of 200 mg/kg compared to diabetic controls. …”
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2312
Metabolic Profile in a Cohort of Young Sicilian Patients with Klinefelter’s Syndrome: The Role of Irisin
Published 2022-01-01“…In both groups of subjects, anthropometric indices, lipid profile, glucose metabolic parameters, HbA1c, the homeostasis model assessment estimate of HOMA-insulin resistance (IR), and the insulin sensitivity index (ISI) were evaluated. …”
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2313
The prognosis and metabolite changes of NSCLC patients receiving first‐line immunotherapy combined chemotherapy in different M1c categories according to 9th edition of TNM classifi...
Published 2024-09-01“…These changes predominantly involved alterations in lipid metabolism, such as decreased diacylglycerol and sphingomyelin, which may impact tumor migration and invasion.…”
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2314
Protein tyrosine phosphatase delta is a STAT3-phosphatase and suppressor of metabolic liver disease
Published 2025-01-01“…Patients with obesity and low hepatic PTPRD expression exhibit increased levels of metabolic risk factors.Conclusion Our data revealed an important regulatory role of the hepatic PTPRD-STAT3 axis in maintaining glucose/lipid homeostasis, which is recapitulated in clinical manifestations of metabolic liver disease.…”
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2315
Inhibitors of Fatty Acid Synthesis Induce PPARα-Regulated Fatty Acid β-Oxidative Genes: Synergistic Roles of L-FABP and Glucose
Published 2013-01-01“…While TOFA (acetyl CoA carboxylase inhibitor) and C75 (fatty acid synthase inhibitor) prevent lipid accumulation by inhibiting fatty acid synthesis, the mechanism of action is not simply accounted for by inhibition of the enzymes alone. …”
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2316
Systemic Lupus Erythematosus, Its Impact on Selected Cardiovascular Risk Factors, and Correlation with Duration of Illness: A Pilot Study
Published 2020-01-01“…The aim of the study was to assess cardiovascular risk factors such as BMI and lipid profile as well as left ventricular ejection fraction among patients with SLE, and a correlation of these factors with duration of the disease. …”
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2317
Molecular genetic and morphological characteristics of Micractinium thermotolerans and M. inermum (Trebouxiophyceae, Chlorophyta) from pyroclastic deposits of the Kamchatka Peninsu...
Published 2024-11-01“…In addition, cells with colorless lipid droplets were detected in aging cultures of both species. …”
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2318
Development and in vitro evaluation of biomimetic injectable hydrogels from decellularized human nerves for central nervous system regeneration
Published 2025-04-01“…Two delipidation solvents, dichloromethane: ethanol (2:1 v/v) and n-hexane: isopropanol (3:1 v/v), were evaluated, with the former achieving optimal lipid removal and better digestion. The resulting solution was crosslinked with genipin, forming an injectable hydrogel (iHPN) that gelled within 12 min at 37 °C and exhibited mechanical stiffness of approximately 400 Pa. …”
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2319
The link between sleep bruxism and oxidative stress based on a polysomnographic study
Published 2025-01-01“…Sleep bruxism is related to oxidative stress markers. Elevated markers of lipid and protein peroxidation may be associated with endovascular damage and cardiovascular risk in sleep bruxers, but further research is needed in this topic.…”
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2320
Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway
Published 2025-02-01“…The strong shear stress altered the membrane lipid microdomain structure of endocardial cells, which activated mTORC2 and PKC and promoted Notch1 cleavage even in the absence of strong ligand stimulation. …”
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