Focal Adhesion Kinase and ROCK Signaling Are Switch-Like Regulators of Human Adipose Stem Cell Differentiation towards Osteogenic and Adipogenic Lineages by Laura Hyväri, Miina Ojansivu, Miia Juntunen, Kimmo Kartasalo, Susanna Miettinen, Sari Vanhatupa

“…Inhibition of these kinases with specific small molecule inhibitors diminished osteogenesis, while inhibition of FAK and ROCK activity led to elevation of adipogenic marker genes AP2 and LEP and lipid accumulation implicating adipogenesis. This denotes to a switch-like function of FAK and ROCK signaling in the osteogenic and adipogenic fates of hASCs. …”
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Effectiveness of Ascophyllum nodosum and Fucus vesiculosus on Metabolic Syndrome Components: A Real-World, Observational Study by Antonio Nicolucci, Maria Chiara Rossi, Massimiliano Petrelli

“…The impact of 180 days of administration of Gdue was assessed on body weight, waist circumference, fasting blood glucose, HbA1c, lipid profile, and blood pressure levels. The likelihood of experiencing a first major cardiovascular event over ten years was estimated using Italian risk charts. …”
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Maresin1 Alleviates Metabolic Dysfunction in Septic Mice: A 1H NMR-Based Metabolomics Analysis by Yu Hao, Hong Zheng, Ruo-Han Wang, Hui Li, Li-Li Yang, Suwas Bhandari, Yong-Jian Liu, Jun Han, Fang Gao Smith, Hong-Chang Gao, Sheng-Wei Jin

“…Maresin1 (MaR1), a new anti-inflammatory and proresolving lipid mediator, has been proven to exert organ-protective effects in septic animal models. …”
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Effect of Oxygen-Reducing Atmospheres on the Safety of Packaged Shelled Brazil Nuts during Storage by Vildes Maria Scussel, Barbara Nantua Giordano, Vanessa Simao, Daniel Manfio, Simone Galvao, Manuel Nazaré Ferreira Rodrigues

“…This work reports the application of oxygen-(O2-) reducing atmosphere methods on stored shelled Brazil nut (Bertholletia excelsa H.B.K.) packs aiming to evaluate the degree of aflatoxin degradation, nuts lipid oxidative stability, fungi control, and hygienic conditions improvement. …”
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Implications of the Intestinal Microbiota in Diagnosing the Progression of Diabetes and the Presence of Cardiovascular Complications by Alina Mihaela Leustean, Manuela Ciocoiu, Anca Sava, Claudia Florida Costea, Mariana Floria, Claudia Cristina Tarniceriu, Daniela Maria Tanase

“…Changes in the intestinal microbiota may influence the host’s sensitivity to insulin, body weight, and lipid and carbohydrate metabolism. Dysbiosis causes activation of proinflammatory mechanisms, metabolic toxicity, and insulin resistance. …”
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Low-density Lipoproteins and Degrees of Cardiovascular Risk in Adults over 40 Years of Age: Case-control Study by Abel Pérez Pavón, Francisco Sánchez Hernández, Karla Doriam Gámez Ávalos, Donovan Casas Patiño, Alejandra Rodríguez Torres

“…<br /><strong>Conclusions:</strong> the average age of the subjects was 62 years, the female sex predominated, with a greater proportion of married people, the level of schooling that predominated was high school, the catholic religion was more frequent and the subjects were from the urban area. Lipid variables such as total cholesterol and LDL-C presented statistical significance in relation to cardiovascular risk.…”
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Cell adhesion and spreading on fluid membranes through microtubules-dependent mechanotransduction by Oleg Mikhajlov, Ram M. Adar, Maria Tătulea-Codrean, Anne-Sophie Macé, John Manzi, Fanny Tabarin, Aude Battistella, Fahima di Federico, Jean-François Joanny, Guy Tran van Nhieu, Patricia Bassereau

“…On fluid substrates like supported lipid bilayers (SLBs), integrin ligands are mobile, and adhesive complexes are traditionally thought unable to anchor for cell spreading. …”
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Effect of cubebin against streptozotocin-induced diabetic nephropathy rats via inhibition TNF-α/NF-κB/TGF-β: in vivo and in silico study by Rahamat Unissa Syed, Sivakumar S. Moni, Weiam Hussein, Taghreed Mohammad Saad Alhaidan, Sondos Mohammed Y. Abumilha, Lama Khalid Alnahdi, Ling Shing Wong, Vetriselvan Subramaniyan, Vinoth Kumarasamy

“…Biochemical parameters such as glucose levels, kidney parameters, lipid profile, oxidative stress, endogenous antioxidant markers, inflammatory cytokines and histopathology were performed. …”
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Non-invasive electron paramagnetic resonance imaging detects tumor redox imbalance induced by ferroptosis by Kazuhiro Kato, Hironobu Yasui, Hideo Sato-Akaba, Miho C. Emoto, Hirotada G. Fujii, Maciej M. Kmiec, Periannan Kuppusamy, Masaki Nagane, Tadashi Yamashita, Osamu Inanami

“…Targeting ferroptosis, cell death caused by the iron-dependent accumulation of lipid peroxides, and disruption of the redox balance are promising strategies in cancer therapy owing to the physiological characteristics of cancer cells. …”
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Relationship between Peripheral Blood miR-181c, miR-101, and Cognitive Impairment in Patients with Diabetes Mellitus Complicated with Acute Stroke by Mengxian Shu, Chunhui Xiang

“…The clinical characteristics and general data (blood glucose and blood lipid) of patients were statistically analyzed. The relative expression levels of miR-181c and miR-101 in peripheral blood were detected by real-time fluorescence quantitative PCR. …”
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Effect and Safety of Pioglitazone-Metformin Tablets in the Treatment of Newly Diagnosed Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease in Shaanxi Province: A Random... by Fu Jianfang, Xiao Wanxia, Gao Xiling, Xu Jing, Yang Wenjuan, Liu Jianrong, He Qingzhen, Ma Kaiyan, Lian Jingxuan, Chen Taixiong, Xu Qian, Li Mengying, Ming Jie, Ji Qiuhe

“…There were no significant statistically differences in blood lipid, body weight, and waist circumference between the test group and the control group. …”
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Development and Evaluation of the Immunogenic Potential of an Unmodified Nucleoside mRNA Vaccine for Herpes Zoster by Shun Zhang, Xiaojie Wang, Tongyi Zhao, Chen Yang, Lulu Huang

“…The optimized mRNA sequences were assessed for protein expression levels in vitro and were subsequently used to develop a vaccine, named Vac07, encapsulated in a lipid nanoparticle (LNP) delivery system. The immunogenicity of Vac07 was evaluated in mice. …”
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Upregulated GSDMB in Clear Cell Renal Cell Carcinoma Is Associated with Immune Infiltrates and Poor Prognosis by Yuanshan Cui, Zhongbao Zhou, Yumeng Chai, Yong Zhang

“…Gasdermin B (GSDMB) is part of the gasdermin (GSDM) family, and they use varying means of domain interactions in molecules to adjust their pore-forming and lipid-binding actions. The GSDM family has roles in the regulation of cell differentiation and proliferation, particularly in the process of pyroptosis. …”
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High Plasma Glucagon Levels Correlate with Waist-to-Hip Ratio, Suprailiac Skinfold Thickness, and Deep Subcutaneous Abdominal and Intraperitoneal Adipose Tissue Depots in Nonobese... by Shajith Anoop, Anoop Misra, Surya Prakash Bhatt, Seema Gulati, Harsh Mahajan, Gokulraj Prabakaran

“…Plasma glucose and glucagon, serum insulin, hepatic transaminases, and lipid profile were measured. Significantly higher levels of fasting and postprandial glucagon (p<0.001) and fasting and postprandial insulin (p<0.001) were seen in patients with T2DM. …”
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2024 Polish recommendations for the management of familial hypercholesterolemia in children and adolescents by Małgorzata Myśliwiec, Marta Bandura, Anna Wołoszyn-Durkiewicz, Matylda Hennig, Mieczysław Walczak, Jarosław Peregut-Pogorzelski, Jolanta Sykut-Cegielska, Maria Miszczak-Knecht, Krzysztof Chlebus, Bartosz Wasąg, Agnieszka Zmysłowska, Maciej Banach

“…This document is an update of the 2014 Position Paper of the Lipid Expert Forum.…”
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PEDF Overexpression Ameliorates Cardiac Lipotoxicity in Diabetic Cardiomyopathy via Regulation of Energy Metabolism by Mao T, Wang Y

“…The excessive accumulation of lipid metabolic intermediates within the myocardium can lead to increased production of reactive oxygen species (ROS) and promote apoptosis. …”
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Effects of Grape Seed Extract, Vitamin C, and Vitamin E on Ethanol- and Aspirin-Induced Ulcers by Vivian Molina Cuevas, Yazmín Ravelo Calzado, Yohani Pérez Guerra, Ambar Oyarzábal Yera, Sonia Jiménez Despaigne, Rosa Mas Ferreiro, Daisy Carbajal Quintana

“…Effects of GSE and vitamins C and E on aspirin- and ethanol-induced gastric ulcer and associated increases of lipid peroxidation in rats were compared. Two experiments were conducted. …”
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Physicochemical properties and bioavailability of bio-calcium products from tilapia bone: A comparative study with synthetic hydroxyapatite by Kornpaka Arkanit, Theeraphol Senphan, Nursakich Issapap, Natthapong Mungmueang, Pornpimol Sriket, Soottawat Benjakul, Chodsana Sriket

“…The median particle sizes varied between 17.39 and 31.05 μm. Lipid oxidation decreased through the processing stages. …”
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HOMA-AD in Assessing Insulin Resistance in Lean Noncirrhotic HCV Outpatients by Matheus Truccolo Michalczuk, Camila Rippol Kappel, Oscar Birkhan, Ana Carolina Bragança, Mário Reis Álvares-da-Silva

“…Fasting glucose, insulin, adiponectin, and lipid profiles were determined. IR was estimated by HOMA-IR and HOMA-AD. …”
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Alteration of fecal microbiome and metabolome by mung bean coat improves diet-induced non-alcoholic fatty liver disease in mice by Dianzhi Hou, Jian Tang, Meili Huan, Fang Liu, Sumei Zhou, Qun Shen

“…Results showed that MBC could effectively alleviative the obese phenotype, reduce the lipid accumulation and insulin resistance, and improve the hepatic oxidative stress and inflammatory response. …”
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