THE LIMBIC SYSTEM IN ADULT HUMAN BRAINS – COMPARATIVE MORPHOMETRIC ANATOMO-IMAGISTIC STUDY by Alin Horatiu Nedelcu, David-Constantin Bulgaru, Simona Alice Partene Vicoleanu, Razvan Tudor Tepordei, Cosmin Gabriel Popa, Roxana-Andreea Popa, Marius Constantin Moraru, Manuela Ursaru

“…The limbic system is made up of a vast network of components such as the cingulate gyrus, the hippocampus and the parahippocampus or ismic formation. …”
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The Neuro-Inflammatory-Vascular Circuit: Evidence for a Sex-Dependent Interrelation? by Catherine Gebhard, Catherine Gebhard, Susan Bengs, Susan Bengs, Achi Haider, Achi Haider, Michael Fiechter, Michael Fiechter, Michael Fiechter

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The association among individual gray matter volume of frontal-limbic circuitry, fatigue susceptibility, and comorbid neuropsychiatric symptoms following COVID-19 by Xuan Niu, Wenrui Bao, Zhaoyao Luo, Pang Du, Heping Zhou, Haiyang Liu, Baoqi Wang, Huawen Zhang, Bo Wang, Baoqin Guo, Hui Ma, Tao Lu, Yuchen Zhang, Junya Mu, Shaohui Ma, Jixin Liu, Ming Zhang

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Understanding gender differences in reasoning and specific paradigm using meta-analysis of neuroimaging by Lina Chen, Lina Chen, Zeqing Zheng, Jin Liang, Jin Liang, Yuerui Lin, Qingqing Miao

“…Notably, females exhibit greater activation in the limbic system compared to males, suggesting that emotional states may play a more prominent role for females when engaging in reasoning tasks.…”
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Emotion Regulation in Enhancing Adolescents’ Academic Performance by Yuliana

“…Brain involvement in emotion and learning are amygdala, hippocampus, prefrontal cortex, limbic system, and insula. Emotion regulation is very important in enhancing adolescent academic performance. …”

Effect of Aromatherapy using Lavender Oil on Audio and Visual Reaction Time: A Quasi-experimental Study by Saroj Chaudhary, Manjinder Kaur, Suman Sharma, Naren Kurmi, Khushboo Shrimali, Soniya Pipliwal, Muskan Singh

“…Introduction: Recently, the aromatheraphy has been a topic of interest in field of research and is reported to exert psychomodulatory effects through the limbic system. Lavender oil is widely researched for its effects on nervous system and shows calming effects. …”
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Serotonin Receptors in Hippocampus by Laura Cristina Berumen, Angelina Rodríguez, Ricardo Miledi, Guadalupe García-Alcocer

“…Neurons and glia, including immune cells, integrate a functional network that uses several serotonin receptors to regulate their roles in this particular part of the limbic system.…”
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Dopamine Agonists and Pathologic Behaviors by Brendan J. Kelley, Andrew P. Duker, Peter Chiu

“…Expression of the D3 receptor is particularly rich within the limbic system, where it plays an important role in modulating the physiologic and emotional experience of novelty, reward, and risk assessment. …”
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The Neuropathology of Autism by Gene J. Blatt

“…The underlying neuropathology of the disorder has been evolving in the literature to include specific brain areas in the cerebellum, limbic system, and cortex. Part(s) of structures appear to be affected most rather than the entire structure, for example, select nuclei of the amygdala, the fusiform face area, and so forth. …”
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Approaches to the Modulation of Abdominal Pain by Emeran A Mayer, Tony Lembo, Lin Chang

“…Even though the precise mechanisms and sites underlying these alterations remain incompletely understood, plausible targets for the development of effective pharmacological treatments are receptors on peripheral terminals of visceral afferent nerves (opioids and serotonin), ion channels and receptors on dorsal horn neurons within the spinal cord (opioids, glutamate, calcitonin gene-related peptide and neurokinin-1), and supraspinal targets in the brainstem within the limbic system and in the prefrontal cortex (serotonin, catecholamines, dopamine and acetylcholine). …”
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Development and Structural Variety of the Chondroitin Sulfate Proteoglycans-Contained Extracellular Matrix in the Mouse Brain by Noriko Horii-Hayashi, Takayo Sasagawa, Wataru Matsunaga, Mayumi Nishi

“…Results showed that early PNN formation was observed in several reticular formations of the brain stem related to the cranial nerves and primary somatosensory cortices. In the limbic system, PNN formation in the hippocampus started earlier than that of the amygdala. …”
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Catatonic Dilemma in a 33-Year-Old Woman: A Discussion by Alexander Koch, Karin Reich, Jan Wielopolski, Marion Clepce, Marie Fischer, Johannes Kornhuber, Norbert Thuerauf

“…The desirable effect of ECT in cases of CS might be dopaminergic stimulation in the striatum and decrease of both the dopaminergic activity in the limbic system and the serotonergic activity on 5-HT2 receptors. …”
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A semi-supervised deep neuro-fuzzy iterative learning system for automatic segmentation of hippocampus brain MRI by M Nisha, T Kannan, K Sivasankari

“…It is a crucial component of the limbic system, which is responsible for regulating emotions, memory, and spatial navigation. …”
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Theoretical Accounts of Gulf War Syndrome: From Environmental Toxins to Psychoneuroimmunology and Neurodegeneration by Eamonn Ferguson, Helen J. Cassaday

“…Such associative mechanisms could be mediated through the hypothalamus and limbic system via vagal nerve innervation and would provide an explanation for the persistence of a set of symptoms (e.g., fever) that should normally be short lived and self-limiting. …”
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Brain mapping, biomarker identification and using machine learning method for diagnosis of anxiety during emotional face in preschool children by Samira Jafari, Hamid Sharini, Aliakbar Foroughi, Afshin Almasi

“…The functional connectivity (FC) for the limbic system were extracted by ROI-to-ROI method. The fMRI biomarkers (FC) were given to machine learning models as input features to diagnose anxiety in children for angry and fearful conditions. …”
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Cerebral 18F-FDG PET in macrophagic myofasciitis: An individual SVM-based approach. by Paul Blanc-Durand, Axel Van Der Gucht, Eric Guedj, Mukedaisi Abulizi, Mehdi Aoun-Sebaiti, Lionel Lerman, Antoine Verger, François-Jérôme Authier, Emmanuel Itti

“…<h4>Results</h4>The SPM12 analysis on the training set exhibited the already reported hypometabolism pattern involving occipito-temporal and fronto-parietal cortices, limbic system and cerebellum. The SVM procedure, based on the t-test mask generated from the training set, correctly classified MMF patients of the testing set with following Se, Sp, PPV, NPV and Acc: 89%, 85%, 85%, 89%, and 87%.…”
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Monoamines, BDNF, Dehydroepiandrosterone, DHEA-Sulfate, and Childhood Depression—An Animal Model Study by O. Malkesman, T. Asaf, L. Shbiro, A. Goldstein, R. Maayan, A. Weizman, N. Kinor, E. Okun, B. Sredni, G. Yadid, A. Weller

“…WKY prepubertal rats exhibited different monoamine levels in the limbic system, reduced DHEA levels in the VTA and lower levels of BDNF in the hippocampus CA3 region compared to controls. …”
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Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications by Vincenzo Salpietro, Agata Polizzi, Gabriella Di Rosa, Anna Claudia Romeo, Valeria Dipasquale, Paolo Morabito, Valeria Chirico, Teresa Arrigo, Martino Ruggieri

“…., delayed myelination and brain atrophy) due to potential corticosteroid-related myelin damage in the developing brain and the possible impairment of limbic system ontogenesis. Idiopathic intracranial hypertension (IIH), a disorder of unclear pathophysiology characterised by increased cerebrospinal fluid (CSF) pressure, has been described in children with hypercortisolism, adrenal insufficiency, and hyperaldosteronism, reflecting the potential underlying involvement of the adrenal-brain axis in the regulation of CSF pressure homeostasis. …”
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Personality Differences of Brain Networks in Placebo Analgesia and Nocebo Hyperalgesia: A Psychophysiological Interaction (PPI) Approach in fMRI by Yu Shi, Shimin Huang, Hongrui Zhan, Yaping Wang, Yanyan Zeng, Guiyuan Cai, Jianming Yang, Wen Wu

“…We found that (1) deactivation differences of the pain-related network and limbic system play an important role in personality differences associated with placebo analgesia and (2) differences of control of anxiety and activation of dorsolateral prefrontal cortex may cause the personality differences observed in nocebo hyperalgesia.…”
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Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study by Gao Z, Cui MJ, Wang HJ, Zhang J, Xu C, Ji LX

“…Low-frequency amplitude measures revealed decreased activity in the left dorsolateral superior frontal gyrus and left postcentral gyrus, among other areas, and increased activity in the right middle frontal gyrus and the opercular part of the right inferior frontal gyrus.Conclusion: Our findings indicate that dysfunction and structural changes in the limbic system and prefrontal cortex may play a pivotal role in the progression from acute to chronic neck pain. …”
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