Editorial by Daniel Halliday

“…Similarly, proposals to tax or otherwise regulate inheritance need to be assessed not just in light of these background facts but in terms of what sort of legal reforms are defensible, how the relevant political narratives seem to evolve, and any likely impact on incentives in the jurisdiction in question. …”
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Flowering Characteristics and Expression Patterns of Key Genes in Response to Photoperiod in Different <i>Chrysanthemum</i> Varieties by Qiuling Zhang, Xueru Li, Shuyu Cai, Junzhuo Li, Jiaying Wang, Yanfei Li, Silan Dai

“…Different <i>chrysanthemum</i> varieties required different light conditions to complete the vegetative stage and reach the floral competent state. …”
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Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges by Weigao Zhang, Hu Liu, Danyang Zhang, Yuguo Yi, Liang Tao, Yunfeng Zhu, Shuxian Huang, Xunan Zhao, Qianchao Shao, Peiqi Li, Yiwen Weng, Wei Lu, Jianfa Zhang, Haibing Zhang, Yuxin Chen, Dan Weng

“…Overall, our findings revealed the role of RIPK1 in maintaining liver homeostasis during metabolic fluctuations and shed light on the intricate interplay between cell death, inflammation, and metabolism.…”
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Association of multiple environmental exposures with rhinitis and asthma symptoms in preschool children: Identifying critical risk factor by Shuang Du, Hao Tang, Han Chen, Yang Shen, Zhiping Niu, Tianyi Chen, Jing Wei, Xia Meng, Wen Su, Qun Wu, Yongqiang Tan, Jing Cai, Zhuohui Zhao

“…Regression modeling of two exposure factors adjusted for each other showed that PM1, PM2.5 and nighttime light(NTL) remained the robust significant associations with rhinitis alone, whereas NO2 had the robust significant association with wheezing &amp; rhinitis and wheezing alone. …”
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Early assessment of IL8 and PD1+ Treg predicts response and guides treatment monitoring in cemiplimab-treated cutaneous squamous cell carcinoma by Teresa Troiani, Fabiana Napolitano, Luigi Formisano, Roberto Bianco, Daniela Russo, Daniela Esposito, Giuseppe Ercolano, Angela Ianaro, Alberto Servetto, Daniela Claudia Maresca, Marcella Scala, Annarita Amato, Stefania Belli, Claudia Maria Ascione, Angela Vallefuoco, Giovanna Attanasio, Fabio Somma, Silvia Varricchio, Massimo Mascolo, Claudia Costa, Alessia Villani, Massimiliano Scalvenzi, Gianfranco Orlandino

“…Finally, IL8 mirrored the tissue results, unlike IL1β, with early (T1) and then sustained (T3) downregulation of its levels in responder patients, while increased in non-responders.Conclusions Taken together, these findings shed light on the significance of early transcriptomic and immune cell modulation in predicting responses to cemiplimab therapy. …”
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Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations by Alia Hadefi, Morgane Leprovots, Gilles Dinsart, Maryam Marefati, Marjorie Vermeersch, Daniel Monteyne, David Pérez-Morga, Anne Lefort, Frédérick Libert, Laurine Verset, Claire Liefferinckx, Christophe Moreno, Jacques Devière, Eric Trépo, Marie-Isabelle Garcia

“…Conclusion: This study provides evidence that the duodenal epithelium of MASH patients exhibits significant alterations in its nutrition-related and barrier functions. This study sheds light on the intricate dynamics of duodenal epithelial alterations in MASH, highlighting potential therapeutic avenues for restoring intestinal functions.…”
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A Comprehensive Study of Type I (Thermonuclear) Bursts in the New Transient SRGA J144459.2–604207 by Tao Fu, Zhaosheng Li, Yuanyue Pan, Long Ji, Yupeng Chen, Lucien Kuiper, Duncan K. Galloway, Maurizio Falanga, Renxin Xu, Xiaobo Li, Mingyu Ge, L. M. Song, Shu Zhang, Shuang-Nan Zhang

“…By superimposing the Insight-HXMT/LE/ME/HE light curves of 37 bursts with similar profiles and intensities, we measured a deficit of X-rays in the 40–70 keV energy band. …”
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Pathogenic variants of TUBB8 cause oocyte spindle defects by disrupting with EB1/CAKP5 interactions and potential treatment targeting microtubule acetylation through HDAC6 inhibiti... by Hui Luo, Jianhua Chen, Cao Li, Tian Wu, Siyue Yin, Guangping Yang, Yipin Wang, Zhihan Guo, Saifei Hu, Yanni He, Yingnan Wang, Yao Chen, Youqiang Su, Congxiu Miao, Yun Qian, Ruizhi Feng

“…These rescue results shed light on the strategy to treat meiotic defects in a certain group of TUBB8 mutated patients. …”
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Live imaging of excitable axonal microdomains in ankyrin-G-GFP mice by Christian Thome, Jan Maximilian Janssen, Seda Karabulut, Claudio Acuna, Elisa D'Este, Stella J Soyka, Konrad Baum, Michael Bock, Nadja Lehmann, Johannes Roos, Nikolas A Stevens, Masashi Hasegawa, Dan A Ganea, Chloé M Benoit, Jan Gründemann, Lia Y Min, Kalynn M Bird, Christian Schultz, Vann Bennett, Paul M Jenkins, Maren Engelhardt

“…Recent studies shedding light on AIS function used predominantly post-hoc approaches since no robust murine in vivo live reporters exist. …”
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A Candidate High-velocity Exoplanet System in the Galactic Bulge by Sean K. Terry, Jean-Philippe Beaulieu, David P. Bennett, Aparna Bhattacharya, Jon Hulberg, Macy J. Huston, Naoki Koshimoto, Joshua W. Blackman, Ian A. Bond, Andrew A. Cole, Jessica R. Lu, Clément Ranc, Natalia E. Rektsini, Aikaterini Vandorou

“…The combination of the host star brightness and light curve parameters yields host star and planet masses of M _host = 0.19 ± 0.03 M _⊙ and m _p = 28.92 ± 4.75 M _⊕ at a distance of D _L = 7.49 ± 0.91 kpc. …”
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Accessible moderate-to-severe obstructive sleep apnea screening tool using multidimensional obesity indicators as compact representations by Xiaoyue Zhu, Chenyang Li, Xiaoting Wang, Zhipeng Yang, Yupu Liu, Lei Zhao, Xiaoman Zhang, Yu Peng, Xinyi Li, Hongliang Yi, Jian Guan, Shankai Yin, Huajun Xu

“…We trained, validated, and tested models with logistic regression and other 5 machine learning algorithms on the clinical dataset and a community dataset. Light gradient boosting machine (LGB) had better performance of calibration and clinical utility than other algorithms in both clinical and community datasets. …”
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Unraveling the degradation mechanism of multiple pyrethroid insecticides by Pseudomonas aeruginosa and its environmental bioremediation potential by Hui Liu, Wen-Juan Chen, Zeling Xu, Shao-Fang Chen, Haoran Song, Yaohua Huang, Kalpana Bhatt, Sandhya Mishra, Mohamed A. Ghorab, Lian-Hui Zhang, Shaohua Chen

“…The findings from this study shed a new light on elucidating the degradation mechanism of P. aeruginosa PAO1 and present a useful agent for development of effective pyrethroid bioremediation strategies.…”
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Network Meta-Analysis of Factors Influencing the Carbon Sink Capacity of Urban Park Green Spaces by Yutong JI, Tianyi LIN, Lian LIU, Xiong LI

“…ObjectiveThis research mainly aims to identify the primary interactions between the factors influencing the carbon sink capacity of urban park green spaces and recognize the most effective landscape design strategies, thereby providing a foundational data set for the further development of a repository of lifecycle design strategies for urban green spaces. In light of the increasingly prominent role of urban green spaces in mitigating climate change, the research also seeks to highlight strategies that balance ecological functions with urban recreational and aesthetic needs.MethodThis research employs the network Meta-analysis method to explore the critical factors influencing the carbon sequestration potential of urban park green spaces, and conduct a systematic quantitative assessment of their respective carbon sink capacity. …”
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Макроморфологічні та мікроморфологічні дослідження ґрунтів Консулівського городища (І ст. до н. е. – ІІ ст. н. е.)... by Жанна Матвіїшина, Анатолій Кушнір, Надія Гаврилюк, Матера Марчин

“…The modern soil in the interval of 0.0–0.8 m corresponds to the characteristics of low-humus southern chernozems formed on a light loamy substrate. The soil below is genetically different, older. …”
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La datation des aqueducs lyonnais : un état des lieux by Aldo Borlenghi, Catherine Coquidé

“…As a result, a global analysis was needed.For the Mont d’Or aqueduct, a single excavation conducted around 30 years ago near the entry into Lyon (52-54 rue de la Favorite) brought to light a sherd of Drag 15/17 type terra sigillata pottery in the canal foundation trench. …”
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Kontribusi Mazhab Teologis Mu'tazilah Dalam Perkembangan Sastra Arab Era Aabbasiyah Studi Analisis Kritis Historis by Zulhelmi Zulhelmi, Hajjah Rafidah binti Haji Abdullah, Shuhaida Hanim binti Mohamad Suhane, Ashwaq Ismail S Batubara, Ashwaq Ismail S Batubara, Delami

“…Moreover, they also contributed to the creation of new literary genres, including al-Munadharah, al-Jadal, al-Mawa'id, and al-Adab al-Dini. In light of these contributions, it is hoped that Muslim scholars in the field of Arabic language and literature will acknowledge these historical achievements. …”
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African army ants at the forefront of virome surveillance in a remote tropical forest by Fritz, Matthieu, Reggiardo, Bérénice, Filloux, Denis, Claude, Lisa, Fernandez, Emmanuel, Mahé, Frédéric, Kraberger, Simona, Custer, Joy M., Becquart, Pierre, Mebaley, Telstar Ndong, Kombila, Linda Bohou, Lenguiya, Léadisaelle H., Boundenga, Larson, Mombo, Illich M., Maganga, Gael D., Niama, Fabien R., Koumba, Jean-Sylvain, Ogliastro, Mylène, Yvon, Michel, Martin, Darren P., Blanc, Stéphane, Varsani, Arvind, Leroy, Eric, Roumagnac, Philippe

“…This suggests that using predators and scavengers such as army ants to sample broad swathes of tropical forest viromes can shed light on the composition and the structure of viral populations of these complex and inaccessible ecosystems. …”
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On the Exponential Atom-Bond Connectivity Index of Graphs by Kinkar Chandra Das

“…The capacity of topological indices to discriminate is a crucial component of their study. In light of this, the literature has introduced the exponential vertex-degree-based topological index. …”
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Comprehensive Assessment of the Effect of Urban Built-Up Land Expansion and Climate Change on Net Primary Productivity by Pengyan Zhang, Yanyan Li, Wenlong Jing, Dan Yang, Yu Zhang, Ying Liu, Wenliang Geng, Tianqi Rong, Jingwen Shao, Jiaxin Yang, Mingzhou Qin

“…Based on land use data, night light data, NPP data, climate data, and a series of social and economic data, we performed a comprehensive analysis of land use change in terms of type and intensity and explored the pattern of urban expansion and its relationship with NPP and climate change for the period of 2000–2015, taking Zhengzhou, China, as an example. …”
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Le travail des peaux et du cuir durant le Haut-Empire à Bordeaux/Burdigala (Gironde), d’après les vestiges mis au jour sur le site de la rue Jean-Fleuret by Vanessa Elizagoyen, Christophe Sireix, Gisèle Allenet de Ribemont, Laurence Benquet, Philippe Borgard, Emilie Claud, Katleen Couchez, Marie-France Dietsch-Sellami, Stéphan Dubernet, Véronique Guitton, Jérôme Hénique, Yannick Le Digol, Martine Leguilloux, Sébastien Lepetz, Fabrice Leroy, Hélène Martin, Alain Queffelec, Stéphanie Raux, Nima Saedlou, Farid Sellami, Laure Simon, Serge Vigier

“…Strong clues point to the immediate proximity of the oldest glassmaking workshop in Burdigala, as well as the presence of horn makers.Within this artisanal neighbourhood, the Jean-Fleuret site offers an exceptional mix of archaeological material, including: 8,800 botanically tanned leather scraps, 26 of which bear tanners’ marks, over 6,300 animal bone remains, wooden objects and equipment, specific tools and alum amphorae from Lipari. This evidence sheds light on techniques used in hide working and the production of leather goods in the Early Roman Empire. …”
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