Combining Bioinformatics and Biophysics to Understand Protein-Protein and Protein-Ligand Interactions by Barry Honig

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Preparation and Characterization of Cyano Complexes of Oxotungsten(IV) with Mannich Base Ligands by Mohita Sharma, Mohd Saleem, Balgar Singh, H. N. Sheikh, B. L. Kalsotra

“…The complexes have been prepared by the reaction of K3Na [WO2(CN)4].6H2O with morpholinobenzyl urea and related ligands in aqueous solution around pH of 7-8. These have been isolated as bis(triphenylphosphine)iminium or cesium salts. …”
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Unbiased picture of the ligand docking process for the hevein protein–oligosaccharide complex by Toshifumi Yui, Takuya Uto

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Synthesis and Anti-microbial Activities Investigation of New Mixed Ligand Complexes by Elaf A. Mousa, Basim I. Al-Abdaly

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Purinergic Receptors of the Central Nervous System: Biology, PET Ligands, and Their Applications by Hamideh Zarrinmayeh PhD, Paul R. Territo PhD

“…Based on their endogenous ligands, purinergic receptors are classified into P1 or adenosine, P2X and P2Y receptors. …”
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Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents by Ahmed A. El-Sherif, Mohamed M. Shoukry, Abeer T. Abd Elkarim, Mohammad H. Barakat

“…Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. …”
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Exploring the Ruthenium-Ligands Bond and Their Relative Properties at Different Computational Methods by Adebayo A. Adeniyi, Peter A. Ajibade

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Ligand-Based Pharmacophore Modeling and Virtual Screening of RAD9 Inhibitors by Nirmal K. Prasad, Vishnupriya Kanakaveti, Siddhartha Eadlapalli, Ramakrishna Vadde, Angamba Potshangbam Meetei, Vaibhav Vindal

“…The results revealed that camptothecin can act as an effective inhibitor among all the ligands taken and can be used as an RAD9 inhibitor. …”
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Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex by Xiaotong Diao, Qinghong Shang, Mengqi Guo, Yubin Huang, Meina Zhang, Xiaoyu Chen, Yinping Liang, Xiangnan Sun, Fan Zhou, Jingjing Zhuang, Shuang-Jiang Liu, Christoph F. A. Vogel, Fraydoon Rastinejad, Dalei Wu

“…Abstract The aryl hydrocarbon receptor (AHR) possesses an extraordinary capacity to sense and respond to a wide range of small-molecule ligands, ranging from polycyclic aromatic hydrocarbons to endogenous compounds. …”
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Improving the charge transport of perovskite nanocrystal light-emitting-diodes through Benzylammonium ligand exchange by Minsik Gong, Dong Gyu Lee, Gwang Yong Shin, Yun Seop Shin, Donghwan Yun, Yunhye Jeong, Sang Wook Park, Chan Beom Park, Yung Jin Yoon, Sung Yong Bae, Yun-Hi Kim, Jin Young Kim, Tae Kyung Lee, Gi-Hwan Kim

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Synthesis and Optical Characterization of Mixed Ligands Beryllium Complexes for Display Device Applications by Vandna Nishal, Devender Singh, Raman Kumar Saini, Vijeta Tanwar, Shri Bhagwan, Sonika Kadyan, Ishwar Singh, Pratap Singh Kadyan

“…Synthesis and photoluminescent behaviour of mixed ligand based beryllium complexes with 2-(2-hydroxyphenyl)benzoxazole (HPB) and 5-chloro-8-hydroxyquinoline (Clq) or 5,7-dichloro-8-hydroxyquinoline (Cl2q) or 2-methyl-8-hydroxyquinoline (Meq) or 8-hydroxyquinoline (q) are reported in this work. …”
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Tetrazenyl-, Imido-, and Azidoaluminate Derivatives of a Sterically Demanding Bis-Silazide Ligand by Han-Ying Liu, Ryan J. Schwamm, Jakub Kenar, Mary F. Mahon, Michael S. Hill

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A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation by Zhishuai Ye, Shanfeng Zhang, Yubo Liu, Shujing Wang, Jianing Zhang, Rongchong Huang

“…Here, we investigated the efficacy of a novel peptide analogue of selectin ligands IELLQAR in atherosclerosis. Methods and Results. …”
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Association of FAS and FAS Ligand Genes Polymorphism and Risk of Systemic Lupus Erythematosus by Bita Moudi, Saeedeh Salimi, Farzaneh Farajian Mashhadi, Mahnaz Sandoughi, Zahra Zakeri

“…FAS/FASL pathway plays a critical role in maintaining peripheral immune tolerance; therefore, the apoptosis genes, Fas and Fas ligand (FasL), could be suitable candidate genes in human SLE susceptibility. …”
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Editorial: Beyond PD-1: novel checkpoint receptors and ligands as targets for immunotherapy by Jesse Haramati, Fabiola Solorzano-Ibarra, Fabiola Solorzano-Ibarra, Dallas B. Flies

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The Key to Unlocking the Chemotherapeutic Potential of PPARγ Ligands: Having the Right Combination by Graham Skelhorne-Gross, Christopher J. B. Nicol

“…Despite extensive preclinical evidence that peroxisome proliferator-activated receptor (PPAR)γ activation protects against tumourigenesis, results from a few clinical trials using PPARγ ligands as monotherapy show modest success. In spite of this, several groups reported exciting results with therapeutic regimens that combine PPARγ ligands with other compounds: chemotherapeutic agents, retinoid x receptor (RXR)α agonists, statins, or cell-to-cell signaling molecules in preclinical cancer models and human trials. …”
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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF RUTHENIUM NITROSYL COMPLEXES CONTAINING POLYPYRIDYL LIGANDS by Dayana P. S. Penha, Thuanny M. de Sousa, Dayane C. de Oliveira, Maria R. H. da Silva, Verônica da S. Oliveira, Daniel de L. Pontes, Ana C. F. de B. Pontes, Tércio de F. Paulo, Francisco O. N. da Silva

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Tailoring PbTe quantum dot Size and morphology via ligand composition by Svetlana Lyssenko, Michal Amar, Alina Sermiagin, Ayan Barbora, Refael Minnes

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CTLA-4 and PD-1 Ligand Gene Expression in Epithelial Thyroid Cancers by Chiara Tuccilli, Enke Baldini, Salvatore Sorrenti, Antonio Catania, Alessandro Antonelli, Poupak Fallahi, Francesco Tartaglia, Susi Barollo, Caterina Mian, Andrea Palmieri, Giovanni Carbotta, Stefano Arcieri, Daniele Pironi, Massimo Vergine, Massimo Monti, Salvatore Ulisse

“…The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. …”
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Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases by Ajit A. Kulkarni, Collynn F. Woeller, Thomas H. Thatcher, Sesquile Ramon, Richard P. Phipps, Patricia J. Sime

“…These ligands modulate multiple cellular pathways via both PPARγ-dependent and PPARγ-independent mechanisms. …”
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