Outcomes of laparoscopic transabdominal preperitoneal hernia repair in the elderly population: a retrospective cohort study by Dawid Golik, Krzysztof Jędras, Przemysław Sroczyński, Grzegorz Dobkowski, Michał R. Janik

“…In the face of rising life expectancy, adequate hernia management in older adults is crucial. …”
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Role of sirtuins in epigenetic regulation and aging control by E. M. Samoilova, S. E. Romanov, D.  A. Chudakova, P. P. Laktionov

“…Additionally, experimental data obtained in animal models, as well as data from population genomic studies, suggest a SIRT effect on life expectancy. At the same time, the diversity of sirtuin functions and biochemical substrates makes it extremely complicated to identify cause­and­effect relationships and the direct role of SIRT in controlling the functional state of the body. …”
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Feasibility of Cognitive Training in Combination With Transcranial Direct Current Stimulation in a Home-Based Context (TrainStim-Home): study protocol for a randomised controlled t... by Ulrike Grittner, Agnes Flöel, Rafal Nowak, Friederike Thams, Daria Antonenko, Merle Rocke, Robert Malinowski

“…Introduction With the worldwide increase of life expectancy leading to a higher proportion of older adults experiencing age-associated deterioration of cognitive abilities, the development of effective and widely accessible prevention and therapeutic measures has become a priority and challenge for modern medicine. …”
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PREVENTION OF ONCOLOGICAL DISEASES AS THE BASIS OF INTERACTION OF ONCOLOGICAL SERVICE WITH PRIMARY LINK OF HEALTH CARE by L. M. Aleksandrova, V. V. Starinsky, A. D. Kaprin, Yu. V. Samsonov

“…More than half of the working age population of deaths in Russia falls on the disease from the group of preventable death, and a third — to preventable causes, depending on the primary and secondary prevention, quality of care, along with a high prevalence of behavioral risk factors (RF), demographic characteristics, marked medical and social reasons for the high mortality rate of the MN: late uptake of the population for health care, lack of alertness in oncology healthcare professionals, patients defects in routing.The leading factor in increasing life expectancy is prevention. Today, prevention is regarded as active method of strengthening and preservation of health, and the currently existing approaches in promoting healthy life mostly only directed at the prevention of behavioral risk factors: tobacco use, poor diet, physical inactivity and harmful use of alcohol. …”
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A Qualitative Study Exploring Facilitators for Improved Health Behaviors and Health Behavior Programs: Mental Health Service Users’ Perspectives by Candida Graham, Crystal Rollings, Sarah de Leeuw, Lesley Anderson, Brenda Griffiths, Nansi Long

“…Mental health service users experience high rates of cardiometabolic disorders and have a 20–25% shorter life expectancy than the general population from such disorders. …”
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Types of Complications and Associated Factors in Patients Undergoing Permanent Cardiac Pacemaker Implantation: A Systematic Review by Sugiharto F, Asmara AD, Sari WP, Freitas LA, Ramdani D, Anna A, Nuraeni A, Trisyani Y, Purnomo Y

“…Although PPM has been proven to improve quality of life and prolong life expectancy in patients with cardiac conduction disorders, post implantation complications still often occur.Purpose: This study aimed to identify types of complications and associated predictors in patients undergoing PPM implantation.Methods: This review used a systematic review design and follows the guidelines of the Cochrane Handbook for Systematic Reviews and the Preferred Reporting Item for Systematic Reviews and Meta-analysis (PRISMA). …”
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A cost-utility analysis of adding SGLT2 inhibitors for the management of type 2 diabetes with chronic kidney disease in Thailand by Natthakan Chitpim, Pattara Leelahavarong, Juthamas Prawjaeng, Sakditat Ittiphisit, Varalak Srinonprasert, Tanawan Kongmalai

“…Adding SGLT2i increased life expectancy (0.42-0.52 years) and QALYs (3.83- 3.91 vs. 3.50 with SoCT alone), but also increased lifetime costs ($1,275–$1,903). …”
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Changes in the transcriptome of the prefrontal cortex of OXYS rats as the signs of Alzheimer’s disease development by N. A. Stefanova, E. E. Korbolina, N. I. Ershov, E. I. Rogaev, N. G. Kolosova

“…The incidence of AD is increasing with increasing life expectancy and gradual aging of the population in developed countries. …”
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Normative Values for Londrina ADL Protocol in Healthy Individuals in Age Group of 40–60 Years among Indian Population: A Cross-Sectional Study by Uttanoor Sreedevi, Gopala Krishna Alaparthi, Shyam krishnan, Kalyana Chakravarthy Bairapareddy, R. Anand, Vishak Acharya

“…Due to increase in the life expectancy and changes related to aging, it is important to assess ADL (activities of daily living) in older adults. …”
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Dental profiling in the archaeological sample of the Illyrian population in Southern Dalmatia, Croatia by Marina Marić, Jelena Dumančić, Marin Vodanović, Igor Borzić, Dinko Radić, Davorka Radovčić, Hrvoje Brkić

“…The average lifespan of the population corresponds to the typical life expectancy during the Late Iron Age.…”
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Caroli Disease (Clinical Observation) by I. G. Nikitin, A. A. Karabinenko, A. E. Nikitin, E. I. Dedov, D. G. Zhukova, E. D. Presnova, S. A. Korvyakov, R. H. Azimov, E. V. Reznik

“…An early diagnosis of Caroli disease is important for preventing complications, improving the quality of life and increasing the life expectancy of patients suffering from this rare disease.…”
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Thresholds for clinical practice that directly link handgrip strength to remaining years of life: estimates based on longitudinal observational data by Sergei Scherbov, Sonja Spitzer, Nadia Steiber

“…This study provides standardised thresholds that directly link HGS to remaining life expectancy (RLE), thus enabling practitioners to detect patients with an increased mortality risk early on.Design Relying on representative observational data from the Health and Retirement Study, the HGS of survey participants was z-standardised by gender, age and body height. …”
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Nano-XRF of lung fibrotic tissue reveals unexplored Ca, Zn, S and Fe metabolism: a novel approach to chronic lung diseases by Bryan Falcones, Maik Kahnt, Ulf Johansson, Barbora Svobodová, Karin A. von Wachenfelt, Charlott Brunmark, Göran Dellgren, Linda Elowsson, Karina Thånell, Gunilla Westergren-Thorsson

“…In the context of Idiopathic Pulmonary Fibrosis (IPF), a debilitating lung condition associated with respiratory complications and reduced life expectancy, nano-XRF presents a promising avenue for understanding the disease’s intricate pathology. …”
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PROMETHEUS: Long-Term Exacerbation and Mortality Benefits of Implementing Single-Inhaler Triple Therapy in the US COPD Population by Gerard Criner, Fernando Martinez, Hitesh Gandhi, Norbert Feigler, Bruce Pyenson, Matthew Emery, Umang Gupta, Muthiah Vaduganathan

“…Applying mean improvements reported in ETHOS for SITT would extend average patient life expectancy 2.2 years for ETHOS-Eligible patients and 1.7 years for Expanded ETHOS-Eligible patients. …”
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One-stop endovenous laser ablation leads to superior outcomes for varicose veins and iliac vein compression by Hong Chen, Chuang Wang, Shenglin Ye, Lulu Wang, Xiaoqiang Li, Lingshang Kong, Xian Zhu, Xiaolong Du, Nan Hu

“…The two-staged BA procedure is recommended for patients with longer life expectancy.…”
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The natural course of cystic pancreatic neuroendocrine tumours in MEN1 by Eline N M van Vliembergen, Carolina R C Pieterman, Annenienke C van de Ven, Arthur J A T Braat, Gerlof D Valk, Joanne M de Laat

“…Pancreatic neuroendocrine tumours (PanNETs) significantly impact life expectancy in multiple endocrine neoplasia type 1 (MEN1). …”
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Prevalence of root caries in relation to various risk factors in a sample of subjects aged (25-64) years in Erbil city: A cross sectional study by Tara Kamal Talib, Vian Omer Majeed

“… Backgrounds: Root surface caries is a significant oral public health problem among humans' due to improvements in health care, long life expectancy, and increasing demand to maintain oral health. …”
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Determinants of Under-Five Child Mortality in Ethiopia: Analysis Using Ethiopian Demographic Health Survey, 2016 by Addisalem Tebeje Zewudie, Abebaw Addis Gelagay, Engidaw Fentahun Enyew

“…Under-five mortality rate is a leading indicator of the level of child health and the overall development in countries which indicate the quality of life of a given population, as measured by life expectancy. Objectives. To identify and analyze factors that may have a significant influence on under-five mortality in Ethiopia. …”
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Family Self-Support in Managing Down Syndrome Children: A Qualitative Study by Farzaneh Noroozi, Zohreh Farrar, Tayebeh Gharibi, Roqayeh Gashmard

“…Also, health policymakers in Iran can take action to increase life expectancy and reduce deaths caused by DS by improving the equitable distribution of health resources and services. …”
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Depression in Patients Diagnosed with Type 2 Diabetes Mellitus by Dinorah Janet Torres Lugo, Iván Castillo Ledo, Iriam Rojas Díaz, Antonio Masot Rangel, Silvia Janet Masot Torres, Pedro González López

“…<strong>Background:</strong> during the evolution of diabetes mellitus, chronic complications may appear that affect life expectancy and health-related quality of life, thus harming the physical and mental health of patients. …”
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