Long-term trends and patterns in ultra-processed food consumption among Korean adults from 1998 to 2022 by Hyeseung Lee, Yesol Yim, Yerin Cho, Jiyeon Oh, Soeun Kim, Yejun Son, Hyesu Jo, Seohyun Hong, Masoud Rahmati, Hanseul Cho, Jiyoung Hwang, Dong Keon Yon

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A Native LH1–RC–HiPIP Supercomplex from an Extremophilic Phototroph by Kazutoshi Tani, Ryo Kanno, Kenji V. P. Nagashima, Mai Kawakami, Naho Hiwatashi, Kazuna Nakata, Sakiko Nagashima, Kazuhito Inoue, Shinichi Takaichi, Endang R. Purba, Malgorzata Hall, Long-Jiang Yu, Michael T. Madigan, Akira Mizoguchi, Bruno M. Humbel, Yukihiro Kimura, Zheng-Yu Wang-Otomo

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Variables associated with cognitive function: an exposome-wide and mendelian randomization analysis by Yong-Li Zhao, Yi-Ning Hao, Yi-Jun Ge, Yi Zhang, Lang-Yu Huang, Yan Fu, Dan-Dan Zhang, Ya-Nan Ou, Xi-Peng Cao, Jian-Feng Feng, Wei Cheng, Lan Tan, Jin-Tai Yu

“…Subsequently, our multivariable analyses identified 41 variables that were significantly associated with at least one cognitive function, spanning categories such as education, socioeconomic status, lifestyle factors, body measurements, mental health, medical conditions, early life factors, and household characteristics. Among these 41 variables, 12 were associated with more than one cognitive domain, and were further identified in all subgroup analyses. …”
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Harnessing new mHealth technologies to Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART trial): a protocol for a randomised controlled trial by Ben J Marais, Joel Negin, James Johnston, Virginia Wiseman, Greg J Fox, Thu Anh Nguyen, Binh Hoa Nguyen, Viet Nhung Nguyen, Justin Beardsley, Guy Barrington Marks, Kavindhran Velen, Tho Dang, Hoang Anh Nguyen, Dinh Hoa Vu, Thu Thuong Do, Cuong Pham Duc, Huu Lan Nguyen, Huu Thuong Pham, Warwick Britton

“…Cost-effectiveness will be presented as an incremental cost per patient successfully treated and an incremental cost per quality-adjusted life-year gained.Ethics Ethical approval for the study was granted by The University of Sydney Human Research Ethics Committee (2019/676).Dissemination Study findings will be disseminated to participants and published in peer-reviewed journals and conference proceedings.Trial registration number ACTRN12620000681954.…”
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Comparing the emotional impact of the UK COVID-19 lockdown in very preterm and full-term born children: a longitudinal study by Zeyuan Sun, Zeyuan Sun, Laila Hadaya, Laila Hadaya, Marguerite Leoni, Marguerite Leoni, Paola Dazzan, Emily Simonoff, Serena J. Counsell, A. David Edwards, Chiara Nosarti, Chiara Nosarti, Lucy Vanes

“…Further rigorous studies are therefore needed to assess the severity of increased risks for this particularly vulnerable group in the context of potentially stressful life changes and adjustments.…”
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Histopathological Characterization and Whole Exome Sequencing of Ectopic Thyroid: Fetal Architecture in a Functional Ectopic Gland from Adult Patient by Rosalinda Yasato Camargo, Cristina Takami Kanamura, Celso Ubirajara Friguglietti, Célia Regina Nogueira, Sonia Iorcansky, Alfio José Tincani, Ana Karina Bezerra, Ester Brust, Fernanda Christtanini Koyama, Anamaria Aranha Camargo, Fernanda Orpinelli R. Rego, Pedro Alexandre Favoretto Galante, Geraldo Medeiros-Neto, Ileana Gabriela Sanchez Rubio

“…Despite the ability of all ectopic thyroids to synthetize specific thyroid proteins and T4, at some point in life, it may be insufficient to support body growth leading to hypothyroidism, as observed in some of the patients.…”
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T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy by Linghua Wang, Siqing Fu, Aung Naing, Funda Meric-Bernstam, Carl Morrison, Joud Hajjar, Mingxuan Xu, Anas Alshawa, Bettzy Stephen, Ying Yuan, Jordi Rodon Ahnert, Abdulrazzak Zarifa, Shrutii Sarda, Timothy Looney, Sapna P Patel, Geoffrey M Lowman, Dzifa Yawa Duose, Jeffrey M Conroy, Evan Kwiatkowski

“…However, they are associated with a unique spectrum of side effects, called immune-related adverse events (irAEs), which can cause significant morbidity and quickly progress to severe or life-threatening events if not treated promptly. …”
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Nature and prevalence of long-term conditions in people with intellectual disability: retrospective longitudinal population-based study by Ashley Akbari, Navjot Kaur, Rania Kousovista, Gemma Lewin, Emeka Abakasanga, Rishika Shivamurthy, Georgina Cosma, Gyuchan Jun, Satheesh Gangadharan

“…Conditions which may usually be expected to emerge later in life are present in younger age groups, such as diabetes, hypertension and chronic arthritis. …”
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Locking compression plate as a sequential external fixator following the distraction phase for the treatment of tibial bone defects caused by fracture-related infection: experience... by Xiriaili Kadier, Kai Liu, Aierbanjiang Shali, Yimurang Hamiti, Sulong Wang, Xin Yang, Alimu Keremu, Aihemaitijiang Yusufu

“…Furthermore, this combined technique could be more beneficial in alleviating psychological burdens, supporting patients’ engagement in rehabilitation, and facilitating a return to normal life. Clinical trial number Not applicable.…”
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Five-Year Prospective Follow-Up of Patients with Hepatitis C Virus Infection Treated with Direct-Acting Antiviral Agents by Zhang Y, Xia H, Fan L, Jiang L, Yang B, Wang F

“…Yaping Zhang,1,2,* Huan Xia,3,* Luchang Fan,1 Lu Jiang,4 Bin Yang,2 Fengmei Wang4,5 1The Third Central Clinical College of Tianjin Medical University, Tianjin Medical University, Tianjin, 300170, People’s Republic of China; 2Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Institute of Hepatobiliary Disease, Nankai University Affiliated Third Central Hospital, Tianjin, 300072, People’s Republic of China; 3Department of Infectious Diseases, Tianjin Second People’s Hospital, Tianjin, 300192, People’s Republic of China; 4Department of Hepatology and Gastroenterology, Tianjin First Central Hospital, Tianjin, 300192, People’s Republic of China; 5Tianjin Key Laboratory of Molecular Diagnosis and Treatment of Liver Cancer, Tianjin First Central Hospitial, Tianjin, 300192, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fengmei Wang; Bin Yang, Email wangfengmeitj@126.com; bioyang@126.comPurpose: The research intended to present prospective data on the long-term prognosis of individuals with hepatitis C virus (HCV) infection who received direct-acting antiviral agent (DAA) treatment.Patients and Methods: Patients who received DAA treatment at Tianjin Third Central Hospital and Tianjin Second People’s Hospital were prospectively enrolled and subsequently underwent a longitudinal follow-up. …”
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The development of a food-group, tree classification method and its use in exploring dietary associations with metabolic dysfunction-associated Steatotic liver disease (MASLD) and... by Amina A. Alawadi, Amrita Vijay, Jane I. Grove, Moira A. Taylor, Guruprasad P. Aithal

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Active Retrograde Extra Backup with a Mother-and-Child Catheter to Facilitate Retrograde Microcatheter Collateral Channel Tracking in Recanalization of Coronary Chronic Total Occlu... by Yong Wang, Xiao-Jiao Zhang, Hong-Wei Zhao, Cheng-Fu Wang, De-Feng Luo, Qing-Kun Meng, Yu Zhu, Jie Tao, Bao-Jun Chen, Yi Li, Ai-Jie Hou, Bo Luan

“…The radiation dose (223.6 ± 112.7 vs. 295.2 ± 129.3, p=0.028), fluoroscopy time (50.6 ± 21.3 vs 62.3 ± 32.1, p=0.030), and contrast volume (301.8 ± 146.7 vs 352.2 ± 179.5, p=0.032) in the ARB group were significantly lower than that in the non-ARB group. There were no life-threatening procedural complications in either group. …”
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Abnormalities in mitochondrial energy metabolism induced by cryopreservation negatively affect goat sperm motility by Shengqin Zang, Shuqi Zou, Xiangyi Chen, Bo Pan, Ao Ning, Jianpeng Qin, Yaozong Wei, Kunlin Du, Jiangfeng Ye, Qiuxia Liang, Yi Fang, Qiongla, Cirenlamu, Tianzeng Song, Tianzeng Song, Guangbin Zhou

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Additifs alimentaires : Inventaire des substances ajoutées aux denrées alimentaires de large consommation dans l’Ouest algérien by Zakaria Lotfi Guaouar, Fatima Zahra Besseguir, Mira Gharbi, Imane Kecir

“… Abstract Introduction- Food additives are used to extend the shelf life of prepared foods or to sweeten a beverage, for example. …”
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mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae by Ting Huang, Siyou Che, Zheng Lv, Danrui Hao, Runyu Wang, Qinxuan Yi, Ling Mei, Yang Yuan, Hang Zou, Yidong Guo, Xinrong Wang, Yiwen Chu, Kelei Zhao

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Community-based HPV self-collection versus visual inspection with acetic acid in Uganda: a cost-effectiveness analysis of the ASPIRE trial by Joel Singer, Angeli Rawat, Heather Armstrong, Josaphat Byamugisha, Gina S Ogilvie, Alex K Mezei, Heather N Pedersen, Stephen Sy, Catherine Regan, Sheona M Mitchell-Foster, Musa Sekikubo, Jane J Kim, Nicole G Campos

“…The model was used to assess the cost-effectiveness of each arm of ASPIRE, as well as an HPV screen-and-treat strategy (‘HPV-ST’) involving community-based self-collected HPV testing followed by treatment for all HPV-positive women at the clinic.Outcome measures The primary outcomes were reductions in cervical cancer risk and incremental cost-effectiveness ratios (ICERs), expressed in dollars per year of life saved (YLS).Results HPV-ST was the most effective and cost-effective screening strategy, reducing the lifetime absolute risk of cervical cancer from 4.2% (range: 3.8%–4.7%) to 3.5% (range: 3.2%–4%), 2.8% (range: 2.4%–3.1%) and 2.4% (range: 2.1%–2.7%) with ICERs of US$130 (US$110–US$150) per YLS, US$240 (US$210–US$280) per YLS, and US$470 (US$410–US$550) per YLS when performed one, three and five times per lifetime, respectively. …”
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Air pollution and health in Eastern India: Findings from a primary survey conducted in West Bengal and Jharkhand by Arup Halder, Aditi Kundu, Arunava Ghoshal

“…Introduction: Exposure to air pollution has long been associated with mortality and shortened life expectancy and has been acknowledged as one of the growing risk factors that affect human health. …”
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HOTSED: A new integrated model for assessing potential hotspots of sediment sources and related sediment dynamics at watershed scale by Manuel La Licata, Alberto Bosino, Seyed Hamidreza Sadeghi, Mattia De Amicis, Andrea Mandarino, Andrea Terret, Michael Maerker

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Preimplantation genetic testing for aneuploidy in severe male factor infertility: protocol for a multicenter randomised controlled trial by Li Wang, Li Jin, Yao Lu, Chen Zhang, He-Feng Huang, Yun Sun, Xian-hua Lin, Meng-xi Guo, Dan-dan Wu, Jian-lin Zhang, Cheng-liang Zhou, Chen-ming Xu, Song-chang Chen, Song-ying Zhang, Xiao-xi Sun, Yan-ting Wu

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An aquaria set‐up for long‐term, multiple‐stressor research in marine organisms by Cristina Gutiérrez‐Zárate, Alfredo Veiga, Andrea Gori, Fabián Gerpe, Leo Domínguez, Alberto Rodríguez, Noelia Arias, Marta Álvarez, Rubén Acerbi, Lucía Vázquez, Juancho Movilla, Marta M. Varela, Rodrigo Alba‐Salgueiro, Joaquín Valencia‐Vila, Covadonga Orejas

“…Here, we present an experimental set‐up suitable to run long‐term experiments, composed of a life support system, a cost‐effective aquaria set‐up and an open‐source controller based on the use of a Raspberry Pi. …”
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