Multi-cancer early detection tests for general population screening: a systematic literature review by Ros Wade, Sarah Nevitt, Yiwen Liu, Melissa Harden, Claire Khouja, Gary Raine, Rachel Churchill, Sofia Dias

“…No meaningful results were reported relating to patient-relevant outcomes, such as mortality, potential harms, health-related quality of life, acceptability or satisfaction. Conclusions All currently available multi-cancer early-detection tests reported high specificity (> 96%). …”
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Risk factors for thromboembolic and bleeding events in anticoagulated patients with atrial fibrillation: the prospective, multicentre observational PREvention oF thromboembolic eve... by Raffaele De Caterina, Kurt Huber, Richard Schilling, Miklos Rohla, Thomas W Weiss, Ladislav Pecen, Giuseppe Patti, Jolanta M Siller-Matula, Renate B Schnabel, Dipak Kotecha, Markus Lucerna, Paulus Kirchhof

“…Objectives We identified factors associated with thromboembolic and bleeding events in two contemporary cohorts of anticoagulated patients with atrial fibrillation (AF), treated with either vitamin K antagonists (VKA) or non-VKA oral anticoagulants (NOACs).Design Prospective, multicentre observational study.Setting 461 centres in seven European countries.Participants 5310 patients receiving a VKA (PREvention oF thromboembolic events - European Registry in Atrial Fibrillation (PREFER in AF), derivation cohort) and 3156 patients receiving a NOAC (PREFER in AF Prolongation, validation cohort) for stroke prevention in AF.Outcome measures Risk factors for thromboembolic events (ischaemic stroke, systemic embolism) and major bleeding (gastrointestinal bleeding, intracerebral haemorrhage and other life-threatening bleeding).Results The mean age of patients enrolled in the PREFER in AF registry was 72±10 years, 40% were female and the mean CHA2DS2-VASc Score was 3.5±1.7. …”
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Patients with MAC Lung Disease Have a Low Visceral Fat Area and Low Nutrient Intake by Kentaro Wakamatsu, Nobuhiko Nagata, Sanae Maki, Hisamitsu Omori, Hiroyuki Kumazoe, Kayoko Ueno, Yuko Matsunaga, Makiko Hara, Koji Takakura, Nagisa Fukumoto, Nobuhisa Ando, Mami Morishige, Takashi Akasaki, Ichiro Inoshima, Shinji Ise, Miiru Izumi, Masayuki Kawasaki

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Perbedaan Kadar Hemoglobin dan Hematokrit Bayi Baru Lahir Akibat Perbedaan Waktu Penjepitan Tali Pusat by Nuriah Arma, Yanwirasti ., Lisma Evareny Evareny

“…This volume supply 40 to 50 mg/kg of extra iron to have 75 mg/kg of body iron baby full-term that can prevent iron deficiency in the first year of life. Therefore, cutting the umbilical cord too soon after birth will reduce the iron of content about 15 to 30%, whereas when delayed 3 minute its can increase the volume red blood cells about 58%. …”
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Detection and Phylogenetic Analysis of Alphacoronaviruses in Bat Populations of Rostov and Novosibirsk Regions of Russia, 2021–2023 by Olesia V. Ohlopkova, Igor V. Popov, Ilia V. Popov, Kristina A. Stolbunova, Marina A. Stepanyuk, Alexey D. Moshkin, Aleksei A. Maslov, Ivan A. Sobolev, Aleksey V. Malinovkin, Elizaveta V. Tkacheva, Daria A. Bogdanova, Ekaterina A. Lukbanova, Alexey M. Ermakov, Alexander Y. Alekseev, Svetoslav D. Todorov, Alexander M. Shestopalov

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Long-Term Effects of Ozone Treatment in Patients with Persistent Numbness and Tingling Secondary to Chemotherapy-Induced Peripheral Neuropathy. A Retrospective Study by Bernardino Clavo MD, PhD, Delvys Rodríguez-Abreu MD, PhD, Saray Galván-Ruiz MD, Mario Federico MD, PhD, Angeles Cánovas-Molina RN, Yolanda Ramallo-Fariña MSc, Carla Antonilli MD, Gretel Benítez MD, Himar Fabelo BEng MSc, PhD, Carla García-Lourve RN, MRes, Damián González-Beltrán CNS, MSc, Ignacio J. Jorge MD, PhD, Francisco Rodríguez-Esparragón BSc, PhD, Gustavo M. Callico MEng, PhD

“…Background: Numbness and tingling secondary to chemotherapy-induced peripheral neuropathy (CIPN) are frequent side effects that limit chemotherapy treatment and quality of life. Successful treatments for CIPN are limited. …”
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Preliminary effectiveness of social prescription and virtual patient information in increasing tertiary prevention among cancer patients (ESPRIT): protocol for a single-centre, ran... by Karen Steindorf, Michael Koller, Michael Leitzmann, Wolfgang Herr, Daniel Heudobler, Lisa Boyer, Anne Herrmann, Tobias Pukrop, Christine Bernardi, Sabine Einhell

“…Introduction Tertiary prevention through physical activity and psychosocial support can positively impact patient outcomes, such as physical function and quality of life (QoL). However, more research is required on the effectiveness of strategies designed to increase the uptake of tertiary prevention programmes among cancer patients. …”
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VCP regulates early tau seed amplification via specific cofactors by Sushobhna Batra, Jaime Vaquer-Alicea, Clarissa Valdez, Skyler P. Taylor, Victor A. Manon, Anthony R. Vega, Omar M. Kashmer, Sourav Kolay, Andrew Lemoff, Nigel J. Cairns, Charles L. White, Marc I. Diamond

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Polityka w dziedzinie edukacji i kształcenia zawodowego by Ryszard Jurkowski

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Edible Alginate–Fungal Chitosan Coatings as Carriers for <i>Lacticaseibacillus casei</i> LC03 and Their Impact on Quality Parameters of Strawberries During Cold Storage by Camila Vilela da Silva Simões, Thayza Christina Montenegro Stamford, Lúcia Raquel Ramos Berger, Alessandra Silva Araújo, José Alberto da Costa Medeiros, Mariane Cajubá de Britto Lira Nogueira, Maria Manuela Estevez Pintado, Silvana Magalhães Salgado, Marcos Antonio Barbosa de Lima

“…This study investigated the efficacy of an innovative edible coating, composed of fungal chitosan and alginate, functionalized with <i>Lacticaseibacillus casei</i> LC03, in both free and microencapsulated forms, to extend the shelf life and enhance the nutritional value of strawberries. …”
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Association Between Surgeon Sex and Days Alive at Home Following Surgery: A Population-Based Cohort Study by Kiyan Heybati, BHSc, Raj Satkunasivam, MD, MS, Khatereh Aminoltejari, MD, MSc, FRCSC, Hannah S. Thomas, MBChB, MS, Arghavan Salles, MD, PhD, Natalie Coburn, MD, MPH, Frances C. Wright, MD, Med, FRCSC, Lesley Gotlib Conn, PhD, Amy N. Luckenbaugh, MD, Sanjana Ranganathan, MD, Carlos Riveros, MD, Colin McCartney, MBChB, PhD, FRCA, FFARCSI, FRCPC, Kathleen Armstrong, MD, MSc, FRCSC, Barbara Bass, MD, Allan S. Detsky, MD, PhD, CM, Angela Jerath, MD, MSc, Christopher J. D. Wallis, MD, PhD

“…More time spent at home after surgery may in turn lower costs of care, resource utilization, and potentially improve quality of life. Further studies are needed to examine these findings across other care contexts.…”
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Thulium laser enucleation of the prostate plus thulium fiber laser therapy for benign prostatic hyperplasia combined with bladder stones by Chen Wang, Yuanwei Li, Yongjun Yang, Junjie Chen, Zhuo Li, Guangqing Song, Jia Chen, Liu Zhe, Yili Teng, Qiang Lu

“…Data collection involved assessing differences in the International Prostate Symptom Score (IPSS), hemoglobin (Hb) levels, maximum urinary flow rate (Qmax), and quality of life (QoL) before and after surgery, along with follow-up results. …”
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Genomic detection of Panton-Valentine Leucocidins encoding genes, virulence factors and distribution of antiseptic resistance determinants among Methicillin-resistant S. aureus iso... by Masoud A. Juma, Tolbert Sonda, Boaz Wadugu, Davis Kuchaka, Mariana Shayo, Petro Paulo, Patrick Kimu, Livin E. Kanje, Melkiory Beti, Marco Van Zwetselaar, Blandina Mmbaga, Happiness Kumburu

“…Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) is a formidable public scourge causing worldwide mild to severe life-threatening infections. The ability of this strain to swiftly spread, evolve, and acquire resistance genes and virulence factors such as pvl genes has further rendered this strain difficult to treat. …”
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Narratives of swiss football players about talent - and positive youth development: The role of social agents and agency. by Philipp Koch, Bryan Charbonnet, Noora Ronkainen

“…Interviews will be analyzed using a narrative life story approach. Results Preliminary findings will be presented, showcasing the diverse and individualized developmental pathways of swiss football players. …”
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Effectiveness of the entomopathogenic fungus Alternaria murispora and the predatory ladybird Harmonia convergens in controlling Phenacoccus solenopsis (Tinsley) by Mohamed El Aalaoui, Said Rammali, Said Rammali, Fatima Zahra Kamal, Fatima Zahra Kamal, Gabriela Calin, Viorica Rarinca, Viorica Rarinca, Viorica Rarinca, Luminita Diana Hritcu, Alin Ciobică, Alin Ciobică, Alin Ciobică, Alin Ciobică, Mohamed Sbaghi

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O perspectivă inedită asupra romanului latin by Carmen-Nicola Jumara

“…Organizing their rich material by following certain patterns, starting from a well-defined intrigue, the Latin writers succeed into creating unitary works, inside which life is to be seen in all its complexity. The Latin novels also make us feel rhythm, conceived as repetition plus variation, by means of which a special effect is achieved: the reader is less interested in the outline. …”
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IMA Genome – F19 by Janneke Aylward, Andi M. Wilson, Cobus M. Visagie, Joseph Spraker, Irene Barnes, Carla Buitendag, Callin Ceriani, Lina Del Mar Angel, Deanné du Plessis, Taygen Fuchs, Katharina Gasser, Daniella Krämer, WenWen Li, Kiara Munsamy, Anja Piso, Jenna-Lee Price, Byron Sonnekus, Chanel Thomas, Ariska van der Nest, Alida van Dijk, Alishia van Heerden, Nicole van Vuuren, Neriman Yilmaz, Tuan A. Duong, Nicolaas A. van der Merwe, Michael J. Wingfield, Brenda D. Wingfield

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In Vivo Chemoprotective Activity of Bovine Dialyzable Leukocyte Extract in Mouse Bone Marrow Cells against Damage Induced by 5-Fluorouracil by Erika Evangelina Coronado-Cerda, Moisés Armides Franco-Molina, Edgar Mendoza-Gamboa, Heriberto Prado-García, Lydia Guadalupe Rivera-Morales, Pablo Zapata-Benavides, María del Carmen Rodríguez-Salazar, Diana Caballero-Hernandez, Reyes Silvestre Tamez-Guerra, Cristina Rodríguez-Padilla

“…Chemotherapy treatments induce a number of side effects, such as leukopenia neutropenia, peripheral erythropenia, and thrombocytopenia, affecting the quality of life for cancer patients. 5-Fluorouracil (5-FU) is wieldy used as myeloablative model in mice. …”
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Does semaglutide reduce alcohol intake in Danish patients with alcohol use disorder and comorbid obesity? Trial protocol of a randomised, double-blinded, placebo-controlled clinica... by Jens Juul Holst, Tina Vilsbøll, Claus Thorn Ekstrøm, Helene Benveniste, Nora D Volkow, Anders Fink-Jensen, Gitte M Knudsen, Mette Kruse Klausen, Tugba Kuzey, Julie Niemann Pedersen, Signe Keller Justesen, Line Rasmussen, Ulla B Knorr, Graeme Mason, George Koob

“…Secondary endpoints include changes from baseline to week 26 in alcohol consumption, smoking status, quality of life, fibrosis-4 score, plasma concentration of phosphatidylethanol, brain gamma-aminobutyric acid (GABA) levels, alcohol cue reactivity, functional connectivity and white matter tract integrity.Status Recruitment started in June 2023.Ethics and dissemination The study is approved by the Ethics Committee of the Capital Region of Denmark, the Danish Board of Health and the Danish Data Protection Agency. …”
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The additional impact of metabolic syndrome on left ventricular deformation and myocardial energetic efficiency impairment in ischemia with nonobstructive coronary arteries patient... by Chen-Yan Min, Yue Gao, Yuan Li, Yi-Ning Jiang, Ying-Kun Guo, Hua-Yan Xu, Rong Xu, Xi Liu, Li-Ting Shen, Zhi-Gang Yang

“…Background Ischemia with nonobstructive coronary arteries (INOCA) has high morbidity, mortality, and poor quality of life. Metabolic syndrome (MetS) is a complex of multiple cardiac metabolic risk factors, significantly increasing the risk of major adverse cardiovascular events in INOCA patients. …”
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