Pelvic Floor Muscle Training vs. Vaginal Vibration Cone Therapy for Postpartum Dyspareunia and Vaginal Laxity by Federico Villani, Izabella Petre, Florina Buleu, Stela Iurciuc, Luciana Marc, Adrian Apostol, Chiara Valentini, Elisabetta Donati, Tommaso Simoncini, Ion Petre, Cristian Furau

“…<i>Background and Objectives:</i> Pelvic floor dysfunction and sexual health issues are common postpartum due to weakened pelvic muscles, significantly impacting women’s quality of life (QoL). Pelvic floor muscle training (PFMT) is a widely used approach to address these issues. …”
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Respiratory and Rehabilitation Expert Consensus on Full-cycle Rehabilitation Assessment and Treatment for Elderly Patients with Chronic Obstructive Pulmonary Disease by CHEN Xin, JIA Jie, DING Yipeng, YE Xujun, DONG Anqin, HE Jing, LIAO Weijing, ZHENG Jieqiao, YU Binbin, CHEN Zuobing, FANG Yuan, YAO Liqing, ZHU Yiping, FU Jianghong, WANG Siyuan, ZHANG Yangxian

“…Through adequate nutritional support, elderly COPD patients can improve their nutritional status, enhance physical strength and quality of life, better manage the disease, and promote rehabilitation (low to moderate-level evidence). …”
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Oxidative Stress and Cardiovascular Complications in Type 2 Diabetes: From Pathophysiology to Lifestyle Modifications by Alfredo Caturano, Maria Rocco, Giuseppina Tagliaferri, Alessia Piacevole, Davide Nilo, Giovanni Di Lorenzo, Ilaria Iadicicco, Mariarosaria Donnarumma, Raffaele Galiero, Carlo Acierno, Celestino Sardu, Vincenzo Russo, Erica Vetrano, Caterina Conte, Raffaele Marfella, Luca Rinaldi, Ferdinando Carlo Sasso

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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

“…The parasite has a highly adaptable life cycle comprising successive rounds of asexual replication in a vertebrate host and sexual maturation in the mosquito vector Anopheles. …”
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Evolution of sub-ice-shelf channels reveals changes in ocean-driven melt in West Antarctica by Karen E. Alley, Richard B. Alley, Alex D. Crawford, Naomi Ochwat, Christian T. Wild, Juliana Marson, Tasha Snow, Atsuhiro Muto, Erin C. Pettit, Sarah F. Child, Martin Truffer, Gabriela Collao-Barrios, Ted A. Scambos

“…We observe examples of channel growth, interactions with ice-shelf features, and systematic changes in sinuosity that give insight into the life cycles of basal channels. We use the last two decades of the record, combined with contemporary ice-flow velocity datasets, to separate channel-path evolution into components related to advection by ice flow and those controlled by other forcings, such as ocean melt or surface accumulation. …”
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Aluminium adjuvants versus placebo or no intervention in vaccine randomised clinical trials: a systematic review with meta-analysis and Trial Sequential Analysis by Christian Gluud, Marija Barbateskovic, Sara Russo Krauss, Janus C Jakobsen, Sesilje Bondo Petersen, Sarah Louise Klingenberg, Snezana Djurisic, Mette Kenfelt, De Zhao Kong

“…No trial reported on quality of life. Aluminium adjuvants versus placebo or no intervention may increase adverse events (RR 1.13, 95% CI 1.07 to 1.20; very low certainty). …”
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Classification of Wheezing Children in Rural Bangladesh by Intensity of Ascaris Infection, Total and Specific IgE Levels, History of Pneumonia, and Other Risk Factors by Haruko Takeuchi, Md Alfazal Khan, Khalequz Zaman, Sayaka Takanashi, S. M. Tafsir Hasan, Mohammad Yunus, Tsutomu Iwata

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Burden of brain and other central nervous system cancer in China, 1990–2019: a systematic analysis of observational data from the global burden of disease study 2019 by Peng Yin, Maigeng Zhou, Fan Zhang, E Wang, Xinran Hou, Zongbin Song, Zhuoyi Liu, Wenyong Long, Zheng Long, Maoen Zhu

“…Objective To evaluate the trends in disease burden and the epidemiological features of central nervous system (CNS) cancer in China from 1990 to 2019.Design A population-based observational study.Setting The incidence, prevalence, death and disability-adjusted life years (DALYs) due to CNS cancer in China, stratified by sex, age and provincial region, were collected from the Global Burden of Disease Study 2019.Participants Data were publicly available and individuals were not involved.Results In 2019, the incident cases of CNS cancer in China were 347 992 (95% UI 262 084–388 896), and the age-standardised rate (ASR) of incidence was 5.69 (95% UI 4.36–6.78) per 100 000 person-years increased by 27.9% compared with that in 1990; meanwhile, CNS cancer caused 63 527 (95% UI 47 793–76 948) deaths in China in 2019, and the ASR of death was 3.5 (95% UI 2.62–4.21) per 100 000 person-years decreased by 9.6%. …”
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Exploring public perceptions and awareness of Parkinson's disease: A scoping review. by Sophie Crooks, Gillian Carter, Christine Brown Wilson, Lisa Wynne, Patrick Stark, Michail Doumas, Matthew Rodger, Emma O'Shea, Gary Mitchell

“…As the disease progresses, individuals living with the disease are likely to lose their independence and autonomy, subsequently affecting their quality of life. People with PD should be supported to live well within their communities but there has been limited research regarding what the public know about PD. …”
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Empirical Analysis of the Impact of the Internet on Social Trust in Chinese Provinces during 2016-2020 by Li Zhengrong, Guo Mengyao, Wang Fang

“…The Internet, one of the hallmarks of information technology, has had a profound impact on social life, enriching public social activities while simultaneously altering traditional patterns of social trust formation. …”
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Analysis on nursing culture and connotation in Shiji Yaoyu (《侍疾要语》中护理文化及内涵探析) by ZHENG Liping (郑莉萍), GUO Hailing (郭海玲), TIAN Runxi (田润溪), WANG Fang (王芳), GAO Ning (高宁), Liu Hongxin (刘红鑫)

“…This article discusses the modern nursing ideology of Shiji Yaoyu from four aspects, including psychological care, life care, disease observation, drug care and nurse competency, in order to enrich the modern nursing thought and promote Chinese medicine nursing culture excavation, inheritance and development. …”
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Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment by Annie S Anderson, Ronan E O’Carroll, Martine Stead, Robert J C Steele, Mary Wells, Maureen Macleod, Anna Campbell, Jacqui A Sugden, Jackie Rodger, Jennifer McKell

“…It was delivered in three face-to-face counselling sessions (plus nine phone calls) by lifestyle coaches over three phases (1: presurgery, 2: surgical recovery and 3: post-treatment recovery).Primary outcome Feasibility measures (recruitment, retention, programme implementation, achieved measures, fidelity, factors affecting protocol adherence and acceptability).Secondary outcomes Measured changes in body weight, waist circumference, walking and self-reported physical activity, diet, smoking, alcohol intake, fatigue, bowel function and quality of life.Results Of 84 patients diagnosed, 22 (26%) were recruited and 15 (18%) completed the study. …”
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Clastic facies classification using machine learning-based algorithms: A case study from Rawat Basin, Sudan by Anas Mohamed Abaker Babai, Olugbenga Ajayi Ehinola, Omer.I.M. Fadul Abul Gebbayin, Mohammed Abdalla Elsharif Ibrahim

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Resveratrol-Based Carbamates as Selective Butyrylcholinesterase Inhibitors: Design, Synthesis, Computational Study and Biometal Complexation Capability by Maja Sviben, Ilijana Odak, Danijela Barić, Milena Mlakić, Ottó Horváth, Lajos Fodor, Sunčica Roca, Ivana Šagud, Irena Škorić

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In vivo brain delivery of BBB-enabled iduronate 2-sulfatase in rats by Will J. Costain, Arsalan S. Haqqani, Greg Hussack, Henk van Faassen, Etienne Lessard, Binbing Ling, Eric Brunette, Dao Ly, Hung Fang, Jennyfer Bultinck, Steven Geysens, Gwenda Pynaert, Kathleen Piens, Stefan Ryckaert, Franck Fudalej, Wouter Vervecken, Danica Stanimirovic

“…IDS and IGF1R3H5-IDS exhibited very short (< 10 min) serum half-life (t1/2α), while constructs containing either HSA or anti-serum albumin sdAbs (R28 or M79) showed 8–11 fold increases in the area under the curve (AUC) in serum. …”
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Preparation and Anti-fatigue Function of Weizmannia coagulans BC99 Emergency Energy Bar by Haodan GUO, Ying WU, Yuqiong WEI, Li CAO, Zhouya BAI, Qiuxia FAN, Nan PENG, Shaobin GU

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Diagnosing glaucoma in optometry practice by A.V. Korneeva, I.N. Isakov, A.V. Kuroyedov, O.N. Onufriichuk

“…The evolving role of optometry personnel in the public health system is underpinned by the increasing number of patients with eye diseases and the growing demand for primary ophthalmic care due to a higher life expectancy of the population. So far, the optometry practice is not always considered as a part of the public health system, but it plays an important role in protecting the vision, as it often helps to identify patients with early stages of refractive disorders and other ophthalmic diseases. …”
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Benefits of physical exercise through multivariate analysis in sedentary adults and elderly: An analysis of physical fitness, health and anthropometrics by Guilherme da Silva Rodrigues, Andressa Crystine da Silva Sobrinho, Gabriel Peinado Costa, Leonardo Santos Lopes da Silva, João Gabriel Ribeiro de Lima, Leonardo da Silva Gonçalves, Larissa Chacon Finzeto, Carlos Roberto Bueno Júnior

“…Using multivariate analysis, we were able to highlight the importance of incorporating regular exercise into daily life to promote active and healthy aging. Furthermore, agility emerged as the most significant intermediate variable after the intervention. …”
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Report on the Academic Symposium: Youth Quotas − The Answer to Changes in Age Demographics? by Igor Dimitrijoski

“…Some speakers challenged the analogy of youth quotas to quotas for women or ethnic minorities, because women and ethnic minorities can’t change their status whereas today’s young people, in the normal course of life, will be old in the future. This means that the disadvantage of a person in his or her young age is just temporal. …”
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Despicable role of epithelial–mesenchymal transition in breast cancer metastasis: Exhibiting de novo restorative regimens by Paras Famta, Saurabh Shah, Biswajit Dey, Kondasingh Charan Kumar, Deepkumar Bagasariya, Ganesh Vambhurkar, Giriraj Pandey, Anamika Sharma, Dadi A. Srinivasarao, Rahul Kumar, Santosh Kumar Guru, Rajeev Singh Raghuvanshi, Saurabh Srivastava

“…Anti-cancer advancements have enabled the killing of BC cells through various therapies; however, cancer relapse is still a major limitation and decreases patient survival and quality of life. Epithelial-to-mesenchymal transition (EMT) is responsible for tumor relapse in several cancers. …”
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