Pathway Of Low Anterior Resection syndrome (LARS) relief after Surgery (POLARiS): protocol for an international, open-label, multi-arm, phase 3 randomised superiority trial within... by Deborah D Stocken, Charles H Knowles, Jared Torkington, David Jayne, Julie Hepburn, Laura Knight, Neil Corrigan, Julie Cornish, Katie Gordon, Ashley Douglas, Kate Wilson, Megan Dale, Julie Croft, Christina Lloydwin, Alexandra Harriet Coxon-Meggy, Judith White, Alun Meggy, Aaron Quyn, Emily Farrow, Kheng-Seong Ng, Hannah Mather, Huey Yi Chong, Betty Tan, Ralph Powell, Andrea Warwick

“…LARS has a significant adverse impact on quality of life (QoL) and symptoms are present in up to 75% of patients in the first year after surgery. …”
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Gaps in U.S. livestock data are a barrier to effective environmental and disease management by Rebecca Logsdon Muenich, Sanskriti Aryal, Amanda J Ashworth, Michelle L Bell, Melanie R Boudreau, Stephanie A Cunningham, K Colton Flynn, Kerry A Hamilton, Ting Liu, Michael L Mashtare, Natalie G Nelson, Barira Rashid, Arghajeet Saha, Danica Schaffer-Smith, Callie Showalter, Aureliane Tchamdja, Jada Thompson

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Long-term real-world evidence of CPX-351 of high-risk patients with AML identified high rate of negative MRD and prolonged OS by Thomas Cluzeau, Fabio Guolo, Edmond Chiche, Paola Minetto, Ramy Rahme, Sarah Bertoli, Luana Fianchi, Jean-Baptiste Micol, Michele Gottardi, Pierre Peterlin, Sara Galimberti, Xavier Thomas, Giuliana Rizzuto, Olivier Legrand, Michela Rondoni, Emmanuel Raffoux, Giambattista Bertani, Alexis Caulier, Michelina D’Argenio, Caroline Bonmati, Atto Billio, Caroline Lejeune, Barbara Scappini, Arnaud Pigneux, Patrizia Zappasodi, Christan Recher, Francesco Grimaldi, Lionel Ades, Roberto M. Lemoli

“…No extensive data are available on measurable residual disease (MRD) and long-term clinical outcome using CPX-351 in AML in real life. We retrospectively collected data from 168 patients in 36 centers in France and Italy who had received 1 or 2 cycles of induction with CPX-351. …”
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Genome-wide linkage mapping of Fusarium crown rot in common wheat (Triticum aestivum L.) by Faji Li, Can Guo, Qi Zhao, Weie Wen, Shengnan Zhai, Xinyou Cao, Cheng Liu, Dungong Cheng, Jun Guo, Yan Zi, Aifeng Liu, Jianmin Song, Jianjun Liu, Jindong Liu, Haosheng Li

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A patient-derived HCC spheroid system to model the tumor microenvironment and treatment response by Emilie Crouchet, Nuno Almeida, Sarah C. Durand, Marie Parnot, Marine A. Oudot, Fabio Giannone, Cloé Gadenne, Natascha Roehlen, Antonio Saviano, Emanuele Felli, Patrick Pessaux, Hong Tuan Duong, Hideki Ohdan, Hiroshi Aikata, Kazuaki Chayama, Thomas F. Baumert, Catherine Schuster

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HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals by Elie Azoulay, Nancy Kentish Barnes, Sheila Nainan Myatra, Maria-Cruz Martin Delgado, Yaseen Arabi, Carole Boulanger, Giovanni Mistraletti, Maria Theodorakopoulou, Vernon Van Heerden, José-Artur Paiva, Oktay Demirkýran, Gabriel Heras La Calle, Abdulrahman Al Fares, Gaston Burghi, Guy Francois, Anita Barth, Jan De Waele, Samir Jaber, Michael Darmon, Maurizio Cecconi

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The bile acid chenodeoxycholic acid associates with reduced stroke in humans and mice by Vera F. Monteiro-Cardoso, Xin Yi Yeo, Han-Gyu Bae, David Castano Mayan, Mariam Wehbe, Sejin Lee, Kumar Krishna-K, Seung Hyun Baek, Leon F. Palomera, Lik Hang Wu, Leroy S. Pakkiri, Sangeetha Shanmugam, Kai Ping Sem, Mun Geok Yew, Matthew P. Parsons, Michael R. Hayden, Leonard L.L. Yeo, Vijay K. Sharma, Chester Drum, Elisa A. Liehn, Sreedharan Sajikumar, Svend Davanger, Dong-Gyu Jo, Mark Y.Y. Chan, Benjamin Y.Q. Tan, Sangyong Jung, Roshni R. Singaraja

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Editorial by Pieter Vanhuysse, Antony Mason, Jörg Tremmel, Markus Rutsche, Maria Lenk

“…The article shows that indicators of sustainability are based all too often on ad hoc partitioning of the life cycle, exemplified by the standard practice of letting adulthood start at 15 or 18, and old age at 65. …”
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Bio-impedancemetry an essential tool in the obesity screening of patients with chronic renal failure [La bio-impédancemétrie un outil indispensable dans le dépistage de l’obésité c... by Samia BOUDANI, Faiza ZERDOUMI, Naouel FZ. BOUMANSOUR, Abbou KADDOUS, Bachir M. GUELLIL

“…Hence the importance of accurate assess-ment of nutritional status in order to preserve not only the renal function of these patients but also their quality of life on dialysis. Objectives. To establish the prevalence of obesity in patients with CKD, before starting extra-renal purification, based on two anthropometric methods: body mass index (BMI) and bioelectrical impedance. …”
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Perspectives from the 2nd International Post-Tuberculosis Symposium: mobilising advocacy and research for improved outcomes by B.W. Allwood, R. Nightingale, G. Agbota, S. Auld, G.P. Bisson, A. Byrne, R. Dunn, D. Evans, G. Hoddinott, G. Günther, Z. Islam, J.C. Johnston, G. Kalyatanda, C. Khosa, S. Marais, G. Makanda, O.M. Mashedi, J. Meghji, C. Mitnick, C. Mulder, E. Nkereuwem, O. Nkereuwem, O.B. Ozoh, A. Rachow, K. Romanowski, J.A. Seddon, I. Schoeman, F. Thienemann, N.F. Walker, D.T. Wademan, R. Wallis, M.M. van der Zalm

“…We aimed to update knowledge on post-TB life and illness, identify research priorities, build research collaborations and highlight the need to embed lung health outcomes in clinical TB trials and programmatic TB care services. …”
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Health and associated economic benefits of reduced air pollution and increased physical activity from climate change policies in the UK by Heather Walton, David Dajnak, Mike Holland, Dimitris Evangelopoulos, Dylan Wood, Christian Brand, Nosha Assareh, Gregor Stewart, Andrew Beddows, Shawn YC Lee, Daniela Fecht, Yunzhe Liu, Bethan Davies, Anna Goodman, Tuan Vu, Sean Beevers

“…Monetary values were applied to the results.The BNZP policy compared with BAU gave 4.9 (95 % confidence interval 1.0–9.0) million life-years gained (LYG) (UK population, to 2154), including 1.1 (0.7–1.6) million LYG from active travel improvements. …”
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Exome sequencing of UK birth cohorts [version 2; peer review: 2 approved, 1 approved with reservations] by Petr Danecek, Amy Hough, John Wright, Karen Ho, Nicholas J. Timpson, Sarah J. Lindsay, Davide Bonfanti, Daniel S. Malawsky, Rafaq Azad, Deborah Plowman, Sara Widaa, Gemma Shireby, Emla Fitzsimons, David Bann, Matthew E. Hurles, Hilary C. Martin, Susan M. Ring, Dan Mason, Michael A. Quail, Wei Huang, Vivek Iyer, Mahmoud Koko, Iaroslav Popov, Laurie Fabian, Gennadii Zakharov, Ruth Y. Eberhardt, Emma E. Wade, Qin Qin Huang

“…They collect information useful for a wide range of life course research domains, and biological samples which can be used to derive data from an increasing collection of omic technologies. …”
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Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024 by --- Various Authors

“…MOVEMENT-DEPENDENT MODULATION OF MULTISENSORY INTEGRATION EARLY IN LIFE: THE DEVELOPMENTAL CONTEXT OF A SPATIAL BODILY-SELF REPRESENTATION • C. …”
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Factors influencing trust in algorithmic decision-making: an indirect scenario-based experiment by Fernando Marmolejo-Ramos, Rebecca Marrone, Malgorzata Korolkiewicz, Florence Gabriel, George Siemens, Srecko Joksimovic, Yuki Yamada, Yuki Mori, Talal Rahwan, Maria Sahakyan, Belona Sonna, Assylbek Meirmanov, Aidos Bolatov, Bidisha Som, Izuchukwu Ndukaihe, Nwadiogo C. Arinze, Josef Kundrát, Lenka Skanderová, Van-Giang Ngo, Giang Nguyen, Michelle Lacia, Chun-Chia Kung, Meiselina Irmayanti, Meiselina Irmayanti, Abdul Muktadir, Fransiska Timoria Samosir, Marco Tullio Liuzza, Roberto Giorgini, Omid Khatin-Zadeh, Hassan Banaruee, Asil Ali Özdoğru, Kris Ariyabuddhiphongs, Wachirawit Rakchai, Natalia Trujillo, Stella Maris Valencia, Armina Janyan, Armina Janyan, Kiril Kostov, Pedro R. Montoro, Jose Hinojosa, Jose Hinojosa, Kelsey Medeiros, Thomas E. Hunt, Julian Posada, Raquel Meister Ko Freitag, Julian Tejada

“…We conclude that having statistical literacy enables individuals to critically evaluate the decisions made by algorithms, data and AI, and consider them alongside other factors before making significant life decisions. This ensures that individuals are not solely relying on algorithms that may not fully capture the complexity and nuances of human behavior and decision-making. …”
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Comparative analysis of C-Reactive protein levels among Non-comorbid, Comorbid, and Multimorbid Hospitalized COVID-19 patients by Maria Shoukat, Haseeb Khan, Moona Nazish, Abdur Rehman, Sheharyar Raashid, Saad Ahmed, Wajid Munir, Abdulwahed Fahad Alrefaei, Massab Umair, Muhammad Osama Bin Abid, Nasim Akhtar, Wajid Zaman, Malik Badshah

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Estimates and trends in death and disability from atrial fibrillation/atrial flutter due to high sodium intake, China, 1990 to 2019 by Qingwen Yu, Lijun Zhao, Ting Tang, Ziyi Xin, Lanlan Feng, Xiyun Rao, Yongmin Shi, Xuhan Tong, Siqi Hu, Yao You, Shenghui Zhang, Jiake Tang, Yongran Cheng, Xingwei Zhang, Mingwei Wang, Ximin Li

“…Results In 2019, the number of AF/AFL deaths and disability-adjusted life years attributable to high sodium intake were 4209.944 (95% UI: [1250.690-8718.238]) and 235484.586 (95% UI: [89136.783-428566.694]), with males comprising 44.81% and 51.95% of cases, respectively. …”
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De l’agglomération antique de Cassinomagus au village de Chassenon (Charente) : un bilan des connaissances by Lucie Carpentier, Sandra Sicard

“…In this context, the Chenevières sanctuary, spanning an area of 7 ha, was to play an essential role in community life as a gathering place, but also as a place of expression of the power of men and gods. …”
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Biofabrication of brain-like living tissue: structure to intelligence by Ling Wang, Sen Wang, Yingjie Liu, Bowen Zhang, Zhaoyu Pan, Luge Bai, Siqi Yao, Chenrui Zhang, Huangfan Xie, Jiankang He, Dichen Li

“…Brain diseases are among the leading threats to human life, yet our understanding of their pathogenic mechanisms and drug development remains limited, largely due to the lack of accurate brain-like tissue models that replicate its complex structure and functions. …”
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Comparative Effectiveness of Rosuvastatin Versus Atorvastatin in Acute Ischemic Stroke Treatment by Joon‐Tae Kim, Ji Sung Lee, Hyunsoo Kim, Beom Joon Kim, Jihoon Kang, Keon‐Joo Lee, Jong‐Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae‐Kwan Cha, Dae‐Hyun Kim, Tai Hwan Park, Kyungbok Lee, Jun Lee, Keun‐Sik Hong, Yong‐Jin Cho, Hong‐Kyun Park, Byung‐Chul Lee, Kyung‐Ho Yu, Mi Sun Oh, Dong‐Eog Kim, Jay Chol Choi, Jee‐Hyun Kwon, Wook‐Joo Kim, Dong‐Ick Shin, Kyu Sun Yum, Sung Il Sohn, Jeong‐Ho Hong, Sang‐Hwa Lee, Man‐Seok Park, Wi‐Sun Ryu, Kwang‐Yeol Park, Juneyoung Lee, Jeffrey L. Saver, Hee‐Joon Bae

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Nonacademic predictors of China medical licensing examination by Jie Sun, Yingying Xie, Ningnannan Zhang, Jingliang Cheng, Meiyun Wang, Bing Zhang, Wenzhen Zhu, Hui Zhang, Shijun Qiu, Xiaojun Xu, Yongqiang Yu, Tong Han, Zuojun Geng, Weihua Liao, Bo Gao, Wen Qin, Feng Liu, Meng Liang, Qiang Xu, Jilian Fu, Jiayuan Xu, Mengge Liu, Peng Zhang, Wei Li, Dapeng Shi, Caihong Wang, Xi-Nian Zuo, Quan Zhang, Feng Chen, Jiance Li, Zhihan Yan, Wen Shen, Yanwei Miao, Junfang Xian, Longjiang Zhang, Kai Xu, Zhaoxiang Ye, Jing Zhang, Guangbin Cui, Chunshui Yu, for the CHIMGEN Consortium

“…Methods In 1202 medical students, we conducted the deletion-substitution-addition (DSA) and structural equation model (SEM) analyses to identify nonacademic predictors of GMKT performance from 98 candidate variables including early life events, physical conditions, psychological and personality assessments, cognitive abilities, and socioeconomic conditions. …”
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